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1- Systemic antifungals
1- Systemic antifungals

... not been established • Although only excreted in tiny amounts from breast milk, it should only be taken by a breastfeeding mother if essential ...
Drug Metabolism Phcy 172 - University of North Carolina at
Drug Metabolism Phcy 172 - University of North Carolina at

... or antagonistic receptor binding affecting biosynthesis, transport, storage, release, and clearance of hormones • Some pesticides have been identified as endocrine disruptors, in particular the thyroid hormone can be affected by: acetochlor, alachlor, fipronil (Frontline), heptachlor, maneb, methomy ...
H2 antagonists and proton pumb inhibitors (1435 H).
H2 antagonists and proton pumb inhibitors (1435 H).

... responsible for final step in gastric acid secretion from the parietal cells. 24 hr inhibition of basal & meal stimulated-acid secretion (90-98%). ...
Red blood cell microrheological changes and drug transport efficiency
Red blood cell microrheological changes and drug transport efficiency

Caring for adult patients suspected of having concealed illicit drugs
Caring for adult patients suspected of having concealed illicit drugs

... having ingested or concealed illicit drugs in body cavities. It covers our legal responsibilities, interactions with the police and provides clinical guidance. This document provides more detailed guidance for the ED regarding the management of patients who are suspected of having concealed illicit ...
neuro 2009 - addiction education home
neuro 2009 - addiction education home

... The retrieval of a memory places it into a plastic state, the result of which is that the memory can be disrupted or even enhanced by experimental treatment. This phenomenon has been conceptualised within a framework of memories being reactivated and then reconsolidated in repeated rounds of cellula ...
Drug Detoxification revisited
Drug Detoxification revisited

... Blocks only Can be used to maintain abstinence No potential for respiratory depression ...
المحاضره السابعه Liver extraction ratio: The liver extraction ratio (ER
المحاضره السابعه Liver extraction ratio: The liver extraction ratio (ER

...  Because there are many other reasons for a drug to have a reduced F value, the extent of first-pass effects is not very precisely measured from F value.  The liver extraction ratio (ER) provides a direct measurement of drug removal from the liver after oral administration of drug.  For example: ...
dostinex - Pharmaline
dostinex - Pharmaline

... Studies in animal models have not demonstrated any teratogenic effect or effects on overall reproductive performance. However, there are no adequate and well-controlled studies in pregnant women. Dostinex should be used during pregnancy only if clearly needed. If conception occurs during therapy wit ...
EFFECT OF pH ON THE PARTITION CO
EFFECT OF pH ON THE PARTITION CO

... To determine the volume of solvents required to dissolve glucose and caffeine according to the standards of Indian pharmacopoeia PRINCIPLE: The absolute and relative solubility of drugs in aqueous and lipid phases of the body are physical properties of primary importance in providing effective conce ...
753_Module3_KidneyFunction
753_Module3_KidneyFunction

... ** Something important must be going on ! Three primary roles for kidneys 1. Excrete metabolic end products and toxins 2. Control concentrations of body fluid constituents (Na, K, Ca, Mg, Glc, H, HC03, Uric acid, etc) 3. Control volume of body fluids ...
More Dosage calculations 2
More Dosage calculations 2

... 5 ml solution. How many mL should patient received? ______________________ 3. Insulin is usually administered in a syringe (U-50 or U-100) that corresponds to the concentration of the insulin stock solution of 100U / mL (U-100). If an insulin syringe is not available, a tuberculin syringe may be use ...
Biost 536, Spring 2013 Homework #1 September 26, 2013, Page 1
Biost 536, Spring 2013 Homework #1 September 26, 2013, Page 1

... trial (96.7%) and requires a relatively small number of confirmatory trials (n=163). 9. The above exercises considered “drug discovery” with randomized clinical trials. What additional issues have to be considered when we are using observational data to explore and try to confirm risk factors for pa ...
Levsin Injection PI - Meda Pharmaceuticals
Levsin Injection PI - Meda Pharmaceuticals

... 712.85. Chemically, it is benzeneacetic acid, α-(hydroxymethyl)-,8-methyl-8-azabicyclo [3.2.1.] oct-3-yl ester, [3(S)-endo]-, sulfate (2:1), dihydrate with the following structure: ...
Key Elements in Warfarin Patient Education
Key Elements in Warfarin Patient Education

...  Duration of therapy: short term vs. long term.  Frequency of visits and blood testing  Importance of compliance with follow up visits  Notify all health professionals that you are on warfarin  Inform anticoagulation provider prior to any scheduled surgeries or dental procedures.  Fall precaut ...
pharm math
pharm math

... •IV flow rate---speed at which IV solution is delivered, volume per time , in mL •flow rate= volume/time •1L of IV solution over 3 hours. what is flow rate? •1000ml/3hrs=333ml/hr •also this means---time=vol / flow rate •how many hours should 1L of D5W last if run 125ml/hr?----time= 1000ml/125ml=8hrs ...
P h a rmaceutical  industry  is  short ... drugs. Whereas in past decades about 50-60 new
P h a rmaceutical industry is short ... drugs. Whereas in past decades about 50-60 new

... minic drugs became popular as miracle drugs. By serendipity, it was also discovered that dimenhydrinate, the complex of 8-chlorotheophylline with diphenhydramine, is an efficient drug against travel sickness; its “clinical trial” happened in 1947, in a sailing of the ship “General Ballou” from New Y ...
Abnormal Psych Note Taking Guide
Abnormal Psych Note Taking Guide

... What is the DSM-5 and why is diagnostic classification of disorders important to psychology? Describe David Rosenhan’s study of “Being Sane in Insane Places” and explain how it demonstrates the danger of using labels to classify disorders. How does the media typically portray people with mental illn ...
Phases of Drug Metabolism - Thomas Jefferson University
Phases of Drug Metabolism - Thomas Jefferson University

... Effect of increasing daily dose on steady-state drug concentrations for drugs undergoing nonlinear ( ) and linear ( ) kinetics ...
substance abuse drugs - University of the Sciences in Philadelphia
substance abuse drugs - University of the Sciences in Philadelphia

... • Impairs memory and may cause delusions, hallucinations and disorientation. • There is NO documented case worldwide of a fatal overdose from taking marijuana. ...
Marijuana
Marijuana

... heroin than those that had not. Adolescent cannabis use can overstimulate and alter the pleasure and reward structures of the brain (dopaminergic system), thus increasing the risk of addiction for people who start to use heroin. (Ellgren 2006) Correlational, could be from inherent property of mariju ...
diuretics
diuretics

... following would be LEAST harmful in a patient with severe hyperkalemia A. Amiloride ...
Cancer Chemotherapy
Cancer Chemotherapy

... (PGP), can confer resistance to a wide variety of drugs. PGP transports drugs out of the cell, which is a process that requires the presence of two ATP-binding domains. These domains are a defining characteristic of this family of ATP-binding cassette (ABC) transporters. The exact mechanism of drug ...
Severe persistant asthma
Severe persistant asthma

... • oral candidiasis occurs more frequently with higher doses • pharyngitis, nausea and cough ...
Slides - Society for Risk Analysis
Slides - Society for Risk Analysis

... Special Features of Chronic Cumulative Disease Processes • Clinical consequences depend on the number of irreversible steps that have occurred in different people (often little detectable change until a large number of steps have occurred). • Effects occur as shifts in population distributions of f ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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