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Review - people.stfx.ca
Review - people.stfx.ca

... excitotoxicity (Lipton and Rosenberg, 1994). In addition, NMDA receptor involvement in memory processing might be rather complex. For instance, NMDA receptors may be required for acquiring memories of novel types of information, but not for memories for which some components have been previously lea ...
Pharmacokinetics and doses of anti-TB drugs in children
Pharmacokinetics and doses of anti-TB drugs in children

... • To rapidly kill most bacilli in order to: - prevent disease progression - prevent transmission of infection - prevent development of drug resistance Continuation phase • To effect cure and prevent relapse (eliminate dormant bacilli) ...
Herbal drugs and drug interactions
Herbal drugs and drug interactions

... In a recent study in rats, it has been demonstrated that combined use of fresh garlic homogenate with captopril had synergistic effects in lowering the blood pressure, and also that captopril increased the antihyperlipidemic activity of garlic (2931). In another study in rats, garlic was observed to ...
substanceabuse
substanceabuse

... • Kudzu (Radix puerariae) has been used in ...
JAMA - Medscape
JAMA - Medscape

... second drug from one of the classes in recommendation 6 (thiazide-type diuretic, CCB, ACEI, or ARB). The clinician should continue to assess BP and adjust the treatment regimen until goal BP is reached. If goal BP cannot be reached with 2 drugs, add and titrate a third drug from the list provided. D ...
EpilEpsy BoARD REviEw MAnuAl Antiepilepsy Drugs: Mechanisms
EpilEpsy BoARD REviEw MAnuAl Antiepilepsy Drugs: Mechanisms

... be estimated with a variety of formulas using serum creatinine levels, including the Modification of Diet in Renal Disease study equation (MDRD), the Cockcroft-Gault equation, and most recently, the Chronic Kidney Disease Epidemiology Collaboration equation (CKD-Epi).10 The MDRD and CKD-Epi are used ...
Adverse event - BioMed Central
Adverse event - BioMed Central

... Adverse events were to be recorded regardless of whether they were thought to be associated with the study or the drug under investigation. An adverse event was considered to be related to use of a study drug if, in the opinion of the investigator, there was a reasonable possibility that the event m ...
Lesson 1: Consciousness
Lesson 1: Consciousness

... Definiton of Hypnosis Hypnosis is an altered state of consciousness that is characterized by increased ...
New (and emerging) Psychoactive Substances (NPS)
New (and emerging) Psychoactive Substances (NPS)

... that are relatively new to recreational drug markets. This term captures all NPS as well as drugs that may not be newly invented, but have recently experienced a resurgence of or increase in use (e.g. 2C-B, DMT). The NPS market has grown rapidly over the past decade and currently encompasses hundred ...
Spironolactone is a drug used to treat excessive hair growth
Spironolactone is a drug used to treat excessive hair growth

... This drug should not be used without an adequate form of birth control. It can cause birth defects (principally feminization of a male fetus) if a woman conceives when she is taking this medication. Allergic reactions, such as rash or itching, can also occur. If you experience any problems or have a ...
Xatral (alfuzosin hydrochloride)
Xatral (alfuzosin hydrochloride)

... Care should be taken when XATRAL is administered to patients with symptomatic orthostatic hypotension, in patients who have had a pronounced hypotensive response to another alpha1blocker or in patients on anti-hypertensive medication or nitrates. As with all alpha1-blockers, alfuzosin has been obser ...
Lipid Excipients in Self Emulsifying Drug
Lipid Excipients in Self Emulsifying Drug

... Use of self emulsifying formulations is limited by their drug loading and limited level of surfactants and cosolvents that can be used with no concern about safety. This may depend on the log P of the drug, and to what extent the surfactant was contributing to its solubilisation within the formulati ...
Hyperkalemia Due to Drug Interactions
Hyperkalemia Due to Drug Interactions

... would also be expected to increase the risk of hyperkalemia. Indeed, life-threatening and fatal hyperkalemia have been reported with these combinations in predisposed patients. It is also important to consider angiotensin II receptor blockers as similar to ACE inhibitors in that they both tend to in ...
An alpha-adrenergic agonist, clonidine functions as an antagonist at
An alpha-adrenergic agonist, clonidine functions as an antagonist at

... BACKGROUND: An alpha-adrenergic agonist, clonidine functions as an antagonist at receptors on cells of the locus ceruleus (found in the primitive pons) and is widely used to treat explosive symptoms in children,1 is effective in the treatment of combat-related post-traumatic stress disorder 2 and is ...
Solutions: October 2011: Addiction by Prescription — For All Ages
Solutions: October 2011: Addiction by Prescription — For All Ages

... Narcotic analgesics. Narcotic analgesics are prescribed because of their pain-relieving properties. Medications that fall within this class include morphine, demerol, codeine and their closely related synthetic cousins. Morphine, one of the most powerful pain relievers available, is used to treat se ...
Mechanism of action
Mechanism of action

... death and serious morbidity, which are most likely to benefit from treatment. This accounts for 1-2% of the obstetric population. 2 Current treatment of preterm labour is reactive, with tocolytics only being used once contractions have started. However, it is now well recognised that labour both at ...
Title Page Option 1 (Title Case 38 Points) Presentation subtitle in
Title Page Option 1 (Title Case 38 Points) Presentation subtitle in

... • Substance Abuse and Mental Health Services Administration. Results from the 2010 National Survey on Drug Use and Health: volume 1: summary of national findings. Rockville, MD: Substance Abuse and Mental Health Services Administration, Office of Applied Studies; 2011. Available from URL: http://oas ...
Receptors and Cytochrome P450 Enzymes With Response to
Receptors and Cytochrome P450 Enzymes With Response to

... its results were far from ideal, as only 58% of patients in both treatment groups achieved complete remission after 6 months without prednisone, and only 36% of patients had disease in stable remission throughout the 18 months of follow-up (2). As the medical community moves closer to the goal of tr ...
Pharmacologic Treatment Options for Obesity: What Is Old Is New Again
Pharmacologic Treatment Options for Obesity: What Is Old Is New Again

... and BLOSSOM [25•], enrolled volunteers who were obese or had BMI≥27 kg/m2 with one comorbidity. The third study, BLOOM DM [26•], enrolled diabetic patients with hemoglobin A1C 7–10 % and BMI 27–45 kg/m2. In this study, all patients (including the placebo group) received counseling in diet and physic ...
Successes, Threats, Challenges and Opportunities of Early
Successes, Threats, Challenges and Opportunities of Early

... and intermediate dose levels; a-wave largely unaffected. This revealed the functional deficit was either on transmission between photoreceptors and bipolar cells, or on the bipolar cells. Tolerance developed during repeat-dosing. ...
Open Access Could Transform Drug Discovery
Open Access Could Transform Drug Discovery

... viability of open access on the process of drug translation. This need is addressed within this study. The literature and intellectual property landscapes of the drug candidate JQ1, which was made available on an open access basis when discovered, and conventionally developed equivalents that were n ...
A Brain Adaptation View of Plasticity: Is Synaptic Plasticity An Overly
A Brain Adaptation View of Plasticity: Is Synaptic Plasticity An Overly

... comparable regions of the brain whether or not they were bein An obvious issue remaining is that with which we opened this section: whether activity or learning causes structural changes in the brain. To address this directly, Black et al. (1990) created adult female rat groups that had 1) a substan ...
DESIGN AND EVALUATION OF CONTROLLED RELEASE TABLETS OF LIPID LOWERING
DESIGN AND EVALUATION OF CONTROLLED RELEASE TABLETS OF LIPID LOWERING

... Nicotinic acid (NA) although known since decades, as an lipid lowering agent drug has not become a first-line treatment due to the strong side effect called flushing occurs when given in Immediate release (IR)dosage form. In the present research, an attempt has been made to formulate controlled rele ...
All about gout and treatments
All about gout and treatments

... buttock or a 5–7 day course of oral steroids, usually prednisolone. Side effects with such a short course are usually limited to mild insomnia or flushing but long term treatment with corticosteroids is best avoided as it can result in weight gain, fluid retention, high blood pressure and diabetes, ...
Novel Detoxification from Opiates
Novel Detoxification from Opiates

... Detoxification With Buprenorphine ...
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Neuropharmacology

Neuropharmacology is the study of how drugs affect cellular function in the nervous system, and the neural mechanisms through which they influence behavior. There are two main branches of neuropharmacology: behavioral and molecular. Behavioral neuropharmacology focuses on the study of how drugs affect human behavior (neuropsychopharmacology), including the study of how drug dependence and addiction affect the human brain. Molecular neuropharmacology involves the study of neurons and their neurochemical interactions, with the overall goal of developing drugs that have beneficial effects on neurological function. Both of these fields are closely connected, since both are concerned with the interactions of neurotransmitters, neuropeptides, neurohormones, neuromodulators, enzymes, second messengers, co-transporters, ion channels, and receptor proteins in the central and peripheral nervous systems. Studying these interactions, researchers are developing drugs to treat many different neurological disorders, including pain, neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, psychological disorders, addiction, and many others.
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