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CYTOARCHITECTURE OF CEREBRAL CORTEX
CYTOARCHITECTURE OF CEREBRAL CORTEX

... • Axon: initial segment; arbor trajectory; terminal shape; branch metrics; boutons; synaptic targets; other • Connections: chemical and electrical; source; location and distribution; other Molecular features •Transcription factors • Neurotransmitters or their synthesizing enzymes • Neuropeptides • C ...
Neuroanatomical Background to Understanding the Brain of the
Neuroanatomical Background to Understanding the Brain of the

... at warp speed through the issue of Descartes’ Error2 to a thesis published recently in arguably one of the top two scientific journals in the world that the universe itself is all at once immaterial, mental, and spiritual,3 and a place where the physics of the material universe falls disappointingly ...
The amygdala, a part of the brain known for its role in fear, also
The amygdala, a part of the brain known for its role in fear, also

... the amygdala links actions and rewards, suggesting that the amygdala plays a role in goal-directed behavior. Still others are finding out how neural circuits in the highly connected human amygdala work with other brain structures to recognize good things and find ways to get them. Such studies may h ...
Brain Mechanisms of Memory and Cognition
Brain Mechanisms of Memory and Cognition

... TEO and TE comprise inferior temporal cortex (called IT). Here, there is less of a retinotopic representation. Subsequently, information passes forward again to the temporal pole and perirhinal cortex (Brodmann’s area 36). These regions are connected to the hippocampal formation in the medial tempor ...
Brain Plasticity and Emotional Regulation
Brain Plasticity and Emotional Regulation

... person is unable to inhibit the expression of the latent fear associations.  This may be associated with pathology in the prefrontalamygdala system. Specifically, inhibition of the amygdala by the vmPFC has been associated with anxiety and mood disorders.  These individuals also show impairments i ...
Neural Correlates of Human Virtue Judgment
Neural Correlates of Human Virtue Judgment

... This study has demonstrated that the brain activations during evaluation of positive deviance from the moral standard, moral beauty, showed different patterns from those of negative deviance, moral depravity. In line with previous reports, moral depravity conditions relative to neutral condition pro ...
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LGN

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Specialized Elements of Orbitofrontal Cortex in Primates
Specialized Elements of Orbitofrontal Cortex in Primates

... ABSTRACT: The orbitofrontal cortex is associated with encoding the significance of stimuli within an emotional context, and its connections can be understood in this light. This large cortical region is architectonically heterogeneous, but its connections and functions can be summarized by a broad g ...
Heart-brain communication Veen, Frederik Martin van der
Heart-brain communication Veen, Frederik Martin van der

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Interactions between Motivation, Emotion and Attention: From
Interactions between Motivation, Emotion and Attention: From

... cells in cortex to be tuned to the specific properties of the stimulus. This effect is enhanced if the presentation is combined with an emotional reaction. Weinberger (1995) has shown that the cortical area representing a stimulus increases in size when it takes part in emotional conditioning. This ...
Interactions between Motivation, Emotion and Attention: From
Interactions between Motivation, Emotion and Attention: From

... cells in cortex to be tuned to the specific properties of the stimulus. This effect is enhanced if the presentation is combined with an emotional reaction. Weinberger (1995) has shown that the cortical area representing a stimulus increases in size when it takes part in emotional conditioning. This ...
15-CEREBRUM
15-CEREBRUM

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Tourette Syndrome - neuropsych
Tourette Syndrome - neuropsych

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Tourette - neuro - neuropsych
Tourette - neuro - neuropsych

... Frey, Kirk, A., Albin, Roger, L. (2006). Neuroimaging of tourette syndrome. Journal of Child Neurology, 21, 672-677 Brain Imaging of control in the first row Brain Imaging of Tourette patient in middle row Comparison in bottom row Looking at the basal ganglia ...
Lecture 9B
Lecture 9B

... 5. The amygdala connections to the perirhinal cortex play an important role in establishing fear memory. While the perirhinal cortex is an elongated structure, the small nucleus of the lateral amygdala is isochronically connected with a large portion of the perirhinal cortex (Pelletier JG, 2002). 6. ...
primary cortex - u.arizona.edu
primary cortex - u.arizona.edu

... current thinking is that the posterior parietal cortex performs this function ...
Reward system - Basic Knowledge 101
Reward system - Basic Knowledge 101

... for Clinical Neuroscience (2nd ed.). New York: McGrawHill Medical. pp. 364–375. ISBN 9780071481274. [2] Nestler EJ (December 2013). “Cellular basis of memory ...
20-Limbic
20-Limbic

... in many of our emotions & motivations, particularly those that are related to survival. Such emotions include fear, anger, & emotions related to sexual behavior. ...
Lecture 37 Notes - MIT OpenCourseWare
Lecture 37 Notes - MIT OpenCourseWare

... not to neocortex. How does olfactory information reach the neocortex? • There are projections from olfactory cortex, amygdala, and basal forebrain structures to the mediodorsal nucleus (medial part) of the thalamus • MDm projects to orbitofrontal neocortex. in the portion of this cortex that extends ...
AHD The Telencephalon R. Altman 4-03
AHD The Telencephalon R. Altman 4-03

... almost always involves the hippocampus and amygdala. • Deficits include profound changes in eating and sexual behaviour, a decrease in aggression levels, and deficits in memory function. – Retro and antegrade ...
Essential circuits of cognition: The brain`s basic operations
Essential circuits of cognition: The brain`s basic operations

... the vast majority of the circuitry of the human brain. If this architecture determines the input / output relations among the disparate constituent modules, it may be possible to arrive at initial hypotheses of the architecture’s overall operation. The system changes via statistical modifications at ...
Orbitofrontal Cortex Encodes Willingness to Pay
Orbitofrontal Cortex Encodes Willingness to Pay

... free trials, they were told how much to bid in the forced trials. The forced Task. Figure 1 describes the time structure of the experiment. Subjects bids were drawn uniformly and independently from $0, $1, $2, or $3 on were instructed not to eat for 4 h before the experiment, which increased each tr ...
The neurobiology of play - Interaction Lab | University of
The neurobiology of play - Interaction Lab | University of

... Figure 2. Major brain regions and their corresponding functionality (as depicted in [8]) ...
The Role of Ventromedial Prefrontal Cortex in Decision Making
The Role of Ventromedial Prefrontal Cortex in Decision Making

... ambiguous decisions. Other lines of evidence suggest that this area of the brain represents quite basic information about the relative ‘‘economic’’ value of options, predicting a role for this region in value-based decision making even in the absence of uncertainty. We tested this prediction in huma ...
(Figure 4B) in 12 month old Cln5-/- mice. To survey effects on glial
(Figure 4B) in 12 month old Cln5-/- mice. To survey effects on glial

... reactive phenotype that is more pronounced compared to results from a study in younger Cln5-/- mice. These data emphasize the progressive nature of the NCLs. Consistent with a mouse model of JNCL (Cln3 null mutant), Cln5-/- mice display a profound loss of sensory relay thalamic neurons, yet no loss ...
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Orbitofrontal cortex



The orbitofrontal cortex (OFC) is a prefrontal cortex region in the frontal lobes in the brain which is involved in the cognitive processing of decision-making. In non-human primates it consists of the association cortex areas Brodmann area 11, 12 and 13; in humans it consists of Brodmann area 10, 11 and 47The OFC is considered anatomically synonymous with the ventromedial prefrontal cortex. Therefore the region is distinguished due to the distinct neural connections and the distinct functions it performs. It is defined as the part of the prefrontal cortex that receives projections from the magnocellular, medial nucleus of the mediodorsal thalamus, and is thought to represent emotion and reward in decision making. It gets its name from its position immediately above the orbits in which the eyes are located. Considerable individual variability has been found in the OFC of both humans and non-human primates. A related area is found in rodents.
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