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text - Systems Neuroscience Course, MEDS 371, Univ. Conn. Health
text - Systems Neuroscience Course, MEDS 371, Univ. Conn. Health

... The basal ganglia are a group of nuclei located near the center of each hemisphere. They are part of the forebrain, lie anterior and lateral to the rostral part of the thalamus, and are intimately involved in cortical functions. The basal ganglia operate to solve a basic behavioral problem; we canno ...
Properties of spike train spectra in two parietal reach areas
Properties of spike train spectra in two parietal reach areas

... Abstract In the lateral intraparietal area (LIP), a saccaderelated region of the posterior parietal cortex (PPC), spiking activity recorded during the memory period of an instructed-delay task exhibits temporal structure that is spatially tuned. These results provide evidence for the existence of ‘d ...
Anorexia nervosa during adolescence and young adulthood
Anorexia nervosa during adolescence and young adulthood

... and placental infarction were all significant independent predictors of later occurrences of AN. Shoebridge and Gowers (2000) explored exposure to stress during pregnancy. Bloomfield et al. (2003) noted that moderate maternal food restriction around the time of conception results in an early fetal c ...
The GABAergic system in schizophrenia
The GABAergic system in schizophrenia

... 1999). In-vivo pharmacological manipulation of the GABAergic system indicates that GABAergic function is potentially relevant to the pathophysiology of schizophrenia. For example, blockade of GABA receptors with picrotoxin in the prefrontal cortex of rats impairs sensorimotor gating, an effect that ...
Human Physiology
Human Physiology

... to be crucial for learning and memory Hippocampus contains neural stem cells that continually produce new neurons (neurogenesis) Stress or depression impede learning and cause hippocampus to shrink Stress reduction and antidepressants return size to normal ...
Cerebrospinal fluid nerve growth factor levels in patients with
Cerebrospinal fluid nerve growth factor levels in patients with

... AD exists in a genetically determined form, known as the familial form (with an autosomal dominant character), and a sporadic form. Postmortem studies of brains from AD patients show cortical atrophy with a loss of from 8% to 10% of brain weight every 10 years of disease progression and histopatholo ...
6.12 Dorsal and Ventral Streams in the Sense of Touch
6.12 Dorsal and Ventral Streams in the Sense of Touch

... The ventral stream – transmitted through the inferotemporal cortex – is the putative ‘what’ pathway. These cortical areas analyze the visual signals to derive cognitive information about the size, shape, and color of the stimulus. These intrinsic properties allow us to recognize such stimuli as dist ...
Origins of Behavioral Neuroscience 1.1 Multiple Choice 1) The mind
Origins of Behavioral Neuroscience 1.1 Multiple Choice 1) The mind

... 40) The significance of Galvani's experiment involving stimulation of an isolated frog muscle is that it proved that A) fluid flow along nerves causes muscles to contract. B) the muscles are activated by electrical nerve signals. C) reflexes can be explained using a hydraulic model. D) a reflex is a ...
Cytoarchitecture of the canine perirhinal and postrhinal cortex
Cytoarchitecture of the canine perirhinal and postrhinal cortex

... have shown that the perirhinal cortex has numerous reciprocal connections with a number of cortical areas in the temporal, parietal, occipital and frontal cortex, both sensory and associative in function. Thus, it is a site of polymodal convergence where particular sensory systems can be introduced ...
14. Assessment of the nervous system
14. Assessment of the nervous system

... innervation except the mimic muscles and tongue muscles that have unilateral innervation from the opposite hemisphere The muscles of upper and lower extremities, lower mimic muscles and tongue muscles have unilateral cortical innervation All the other muscles (the muscles of neck, ...
Identification of neural circuits involved in female genital responses
Identification of neural circuits involved in female genital responses

... (57, 70). The MPO is also identified as a crucial area for the mediation of female pacing behavior (25, 102), and activation of the MPO results in increased blood flow to the vagina and increases vaginal wall tension (24). Both the VMN and MPO send descending projections to the PAG (26, 41, 52, 63, ...
2 Brain and Classical Neural Networks
2 Brain and Classical Neural Networks

New insights into the roles of microRNAs in drug addiction and
New insights into the roles of microRNAs in drug addiction and

... interaction with the mesolimbic dopaminergic system, leading to persistent alterations (neuroplastic, structural and functional) in the reward-related and memoryrelated brain centers. An overview of the pathways involved in miRNA regulation of gene expression in addiction is shown in Figure 1. Long- ...
PDF hosted at the Radboud Repository of the Radboud University Nijmegen
PDF hosted at the Radboud Repository of the Radboud University Nijmegen

... career of this analytic approach we are still lacking an appropriate under­ standing of the brain’s integrative functions: How do all the known compo­ nents interact as a system, how can they develop synergy and be integrated into a functional whole? How do networks of neurons aquire those emergent ...
On the computational architecture of the neocortex
On the computational architecture of the neocortex

... The idea of the present two-part paper is that, at the appropriate level of analysis, there are certain uniformities in the structure of the brain that suggest that some simple general principles of organization must be at work. If this is the case, looking at the tasks performed by the brain from a ...
Glutamatergic activation of anterior cingulate cortex produces
Glutamatergic activation of anterior cingulate cortex produces

... paired with a particular compartment in the place-conditioning apparatus, rats with posttraining r-ACC sham lesions spent less time in the formalin-paired room (i.e., CPA was Figure 1 ACC lesions after training do not affect expression of place aversion. (a) Examples of the largest produced; 389.8 ± ...
The organization of the cortical motor system: new concepts
The organization of the cortical motor system: new concepts

... from various areas belonging to the ‘dorsal visual stream’ (among them areas MST and MT) that are involved in the analysis of optic flow and motion (Maunsell and Van Essen, 1983; Ungerleider and Desimone, 1986; Boussaoud et al., 1990). In addition, VIP receives somatosensory information from areas P ...
prenatal formation of cortical input and development of
prenatal formation of cortical input and development of

... Injection sites. The location and extent of the injection sites were mapped postmortem using microscopic examination of serial sections. In addition, corticothalamic projections and other subcortical terminations were used as a further source of data relevant to defining the injection site. Only cas ...
On the computational architecture of the neocortex
On the computational architecture of the neocortex

... The idea of the present two-part paper is that, at the appropriate level of analysis, there are certain uniformities in the structure of the brain that suggest that some simple general principles of organization must be at work. If this is the case, looking at the tasks performed by the brain from a ...
uncorrected proof - Università degli Studi di Parma
uncorrected proof - Università degli Studi di Parma

... providing ‘‘sufficient basis for agentive understanding’’ (see Pacherie & Dokic, 2006, p. 106), or as playing *by means of motor simulation *a major role in social cognition (Jacob & Jeannerod, 2004). The chimps’ inability to understand others as intentional agents, however, turned out to be only ap ...
Neural mechanisms of the cognitive model of depression
Neural mechanisms of the cognitive model of depression

... dysfunctional attitudes whereby he or she views themself as defective and day-to-day life as rife with struggle, and assumes that their current difficulties or suffering will continue indefinitely 1. The activation of these dysfunctional attitudes increases the likelihood that the depressed person w ...
Impaired associative learning in schizophrenia: behavioral and
Impaired associative learning in schizophrenia: behavioral and

... Primate studies indicate a general separation of the extra-striate visual streams into the dorsal (spatial location, parietal cortex) and ventral (object identity) pathways (Ungerleider 1995). This separation and cooperation between systems is consistent with in vivo imaging studies that suggest rel ...
Review Questions
Review Questions

... 2. Which of the following statements does not describe correctly the ventricular cavity? A. The lateral ventricles are shaped like a butterfly in the forebrain. B. The third ventricle forms a vertical slit between the two thalami. C. The cerebral aqueduct is the narrow opening in the midbrain. D. Th ...
- Philsci
- Philsci

... robotic prostheses is possible. Indeed, after a short learning period, high proficiency in braincontrolling the cursor, both directly and indirectly through robot movements, has been achieved. Interestingly, the monkeys still moved their own limbs at the beginning of the “brain control” phase, even ...
Soltis Autism: a Spectrum of Research Abby Soltis Final Draft Senior
Soltis Autism: a Spectrum of Research Abby Soltis Final Draft Senior

... of 8 autistic brains when compared to 10 control brains (Lee et al, 2002). Decreased levels of binding to the high affinity receptor were also present in the parietal cortex (Perry et al., 2001). Transversely, there was an increase in binding to the low affinity nicotinic receptor, consisting of the ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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