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doc - physiologicalcomputing.org
doc - physiologicalcomputing.org

... Molnar-Szakacs & Uddin, 2013; Spreng et al., 2013) and includes: inferior frontal gyrus, premotor cortex, anterior insula, primary sensory and primary motor cortices, superior temporal sulcus and rostral part of the inferior parietal lobule. This network may simulate the mental states of others by e ...
Document
Document

... It was hoped that Parkinson’s might be alleviated by replacing the chemical. It was thought that the tremors of Parkinson’s disease resulted from the death of nerve cells that produced dopamine, and thus the affliction became the first illness attributed to neurotransmitter deficiency. Dr. Carolyn R ...
Chapter 11: Sex differences in spatial intelligence
Chapter 11: Sex differences in spatial intelligence

... Various lines of research support the notion that we have a specialised brain region for processing faces. Neurons in monkeys appear to be selectively responsive to faces, patients with prosopagnosia are unable to recognise familiar faces (but can recognise other objects and can identify features of ...
Memory Cure -- through ‘brain specific nutrients’?
Memory Cure -- through ‘brain specific nutrients’?

... an impression that dovetails with the experimental literature. In view of these observations, it is natural that the public has an interest in supplements that are touted to improve memory, forestall memory decline, or help remedy age-related declines in memory. These supplements are easily availabl ...
Mechanisms for Sensing Fat in Food in the Mouth
Mechanisms for Sensing Fat in Food in the Mouth

... salivary lipase which could release fatty acid from fat in rats to activate such a mechanism, is hardly present in humans (Gilbertson and others 1997; Gilbertson 1998), so that this mechanism may not be important in humans. To the extent that free fatty acids are present in foods, they may impart an ...
Impact of thousand-and-one amino acid 2 kinase
Impact of thousand-and-one amino acid 2 kinase

... The initial experiments were done on cultured mouse cortical neurons using Taok2 shRNA and rTAOK2 constructs. TAOK2 shRNA or short hairpin RNA targeted different coding sequences of TAOK2 to acutely knock down its expression and rTAOK2 or resistant version of TAOK2 cDNA was used to rescue the TAOK2 ...
Human Neural Systems for Face Recognition and Social
Human Neural Systems for Face Recognition and Social

... which brain regions participate in a perceptual or cogntitive function and how their participation is modulated by other processes, such as attention or memory, but imaging data cannot indicate which of these brain regions are critical for the successful performance of a perceptual or cognitive oper ...
THALAMUS
THALAMUS

... 1.Thalamocortical cells and thalamic reticular cells can generate action potentials either as rhythmic bursts or as tonic, single-spike acticvity, depending upon the membrane potential of the cell. Activation of muscarinic, alfa1-adrenergic, H1-histaminergic or metabotropic glutamate receptors (mGl ...
9.14 Questions on chapter 1 of Brain Structure and Its
9.14 Questions on chapter 1 of Brain Structure and Its

... establish the existence of a major pathway taken by visual information to the neocortex? What belief was destroyed by the experiments? 10) What electrophysiological method can be used to verify the existence of a direct axonal pathway from one location to another in the CNS? It was used by Sherringt ...
Neurons
Neurons

...  A strong stimulus can trigger more neurons to fire, and to fire more often, but all action potentials are of the ...
Chapter 4
Chapter 4

... • Like its relative amphetamine, MDMA (popularly called “ecstasy”) causes noradrenergic transporters to run backwards, causing the release of NE and inhibiting its reuptake. • This site of action is apparently responsible for the drug’s excitatory effect. ...
03/14 PPT
03/14 PPT

... in olfactory bulb. The glomeruli serve as modules, and are selectively sensitive to particular odors ...
Rule-Selection and Action-Selection have a Shared
Rule-Selection and Action-Selection have a Shared

... frontal regions in tasks of cognitive control (Duncan and Owen 2000; Duncan 2006); similar properties of parietal and prefrontal neurons in tasks of working memory and cognitive control (Chafee and Goldman-Rakic 1998, 2000; Nieder and Miller 2004; Stoet and Snyder 2004); and the reciprocal interacti ...
Cognitive Science: Emerging Perspectives and Approaches
Cognitive Science: Emerging Perspectives and Approaches

... the ACT-R has a perceptual-motor module that interfaces with the world. All the modules in ACT-R can only be accessed through their buffers. Soar (Newell, 1990) employs searching through a problem space that brings the system gradually closer to and eventually reach a goal state. Soar is based on a ...
Background Presentation
Background Presentation

... – Nogo trial (asterisk): maintain fixation – no saccade ...
Central Nervous System I. Brain - Function A. Hindbrain 1. Medulla
Central Nervous System I. Brain - Function A. Hindbrain 1. Medulla

... The anterior rami of the spinal nerves, except for thoracic nerves T2-T12 do not go directly to the body structures they supply. Instead they form networks or plexuses on each side of the body by joining various neurons from the anterior rami of adjacent spinal nerves. Emerging from the plexuses is ...
How the prefrontal executive got its stripes
How the prefrontal executive got its stripes

... have fewer than six layers (limbic areas), leading to adjacent areas that have six layers (eulaminate) and finally to eulaminate areas with the best delineated layers. Changes in laminar structure are accompanied by differences in cellular features across areas. These changes are exemplified by a hi ...
Age-dependent effect of cholinergic lesion on dendritic morphology
Age-dependent effect of cholinergic lesion on dendritic morphology

... velocity in fibers projecting from basal forebrain cholinergic nuclei to frontal cortex is decreased, apparently due to demyelinization [3], and changes in frontal cortical EEG have also been documented [47]. Age-related increases in glial density [40] and decreases in synaptic density [50] have als ...
The Nervous System
The Nervous System

The Information Processing Mechanism of the Brain
The Information Processing Mechanism of the Brain

... In the brain the combination of several neural networks, together with other Central Nervous System components, produce complex meaningful operations which make up purposeful human behaviour. (The analogy between transistor and network is somewhat stretched but, in essence, the neural network is a u ...
Internal carotid artery
Internal carotid artery

... controlling movement of opposite half of body except lower limb & perineum, also supplies the area of brain responsible for receiving sensations from opposite half of body except lower limb & perineum. It supplies also motor speech area of the brain. 2. Anterior cerebral artery supplies an area know ...
Monkey and humans exhibit similar motion
Monkey and humans exhibit similar motion

... that the underlying motion-sensitive neurons targeted by our adapter stimulus respond differentially to a range of low dot densities, and that their responses saturate at or around 10 dots per deg2. This is consistent with the macaque data (Snowden et al. 1991, 1992), in which an initial rapid incre ...
Timing of Impulses From the Central Amygdala and Bed Nucleus of
Timing of Impulses From the Central Amygdala and Bed Nucleus of

... the stria terminalis (BNST) are thought to subserve distinct functions, with the former mediating rapid fear responses to discrete sensory cues and the latter longer “anxiety-like” states in response to diffuse environmental contingencies. However, these structures are reciprocally connected and the ...
Learning Objectives
Learning Objectives

Emotion and decision-making explained: A prEcis
Emotion and decision-making explained: A prEcis

... involves the combination of many features in a particular spatial relationship (Rolls, 2008; Rolls & Deco, 2002). It may be because there is less sophisticated cortical processing of visual stimuli in this way that other sensory systems are also organized more simply in rodents, with, for example, s ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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