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Computational cognitive neuroscience: 10. Prefrontal Cortex (PFC)
Computational cognitive neuroscience: 10. Prefrontal Cortex (PFC)

... • Working memory, a core executive function, is a cognitive memory buffer that is responsible for the transient holding, processing, and manipulation of information. • Distinction from the short-term memory: – working memory is a short-term memory buffer that allows for the manipulation of stored in ...
rapid eye movement sleep deprivation induces acetylcholinesterase
rapid eye movement sleep deprivation induces acetylcholinesterase

... Using the flower-pot method, adult male albino rats were deprived of REM sleep for a period of72, 96, and 120 h and perfused brains were then sectioned with a vibratome and stained histochemically for AchE. In comparison to control animals, marked positive AchE ...
The role of metabotropic glutamate receptors in Alzheimer`s disease
The role of metabotropic glutamate receptors in Alzheimer`s disease

... Glutamate receptors mediate most of the excitatory neurotransmission in the mammalian central nervous system and also participate in plastic changes in the efficacy of synaptic transmission underlying memory and learning, and the formation of neural networks during development (Mayer and Westbrook 1 ...
Data Supplement
Data Supplement

... Catwalk). This test was evaluated in a prior study (Pollak and Buckwalter, unpublished data), and limb swing speed and stride length were pre-specified variables for this study based on their high correlation with stroke size in the prior study. Mice were trained once a week for three weeks prior to ...
Spinal cord
Spinal cord

... Tube of neural tissue continuous w/ the medulla at the base of the brain and extends about 17” to just below the last rib. (Ends at L1) Majority of the SC has the diameter of your thumb Thicker at the neck and end of the cord (cervical and lumbar enlargements) b/c of the large group of nerves connec ...
Olfactory Bulb Simulation
Olfactory Bulb Simulation

... 1. Odors are first received on olfactory epithelium, where 1000 different types of receptors are present ...
Reply: The cuneiform nucleus may be involved in the regulation of
Reply: The cuneiform nucleus may be involved in the regulation of

... the pedunculopontine tegmental area pars dissipata in rats resulted in motor deEcits, which is consistent with the hypothesis that the anterior pedunculopontine nucleus (the homologue to the pedunculopontine tegmental area pars dissipata in rodents), has functions related primarily to motor control, ...
The Somatosensory System
The Somatosensory System

... • Deep gray matter structure part of the diencephalon • Convey different types of input to the cortex ...
THE SYNAPSE
THE SYNAPSE

... apposition at the synapse but not in direct contact. The pre- and postsynaptic membranes are separated by a gap, the synaptic cleft. Chemical transmitters bridge this gap by diffusing from release sites on the presynaptic side to receptors on the postsynaptic side. A variety of ultrastructural speci ...
CHAPTER 3 Neuroscience and Behavior
CHAPTER 3 Neuroscience and Behavior

... positively charged ions to rush in at rates as high as 100 million ions per second. The sudden arrival of these positive ions causes the charge within the nearby part of the cell to change momentarily from negative to positive. When the positive charge reaches a critical level, the “trigger” is pull ...
Evolution of the Size and Functional Areas of the Human Brain
Evolution of the Size and Functional Areas of the Human Brain

... The evolution of the human brain has been one of the most significant events in the evolution of life. Although the outline of how and why this happened is being filled in, many fundamental questions remain to be answered. The fossil record, in concert with a comparative neuroanatomical analysis of cl ...
Exam 5 Study Guide
Exam 5 Study Guide

... Understand how the makeup of the spinal cord changes from the superior to inferior ends. Understand what makes white and gray matter. Identify the meninges within the spinal cord and identify the epidural space on a diagram or on a model. Identify rootlets and roots. Distinguish the function of ante ...
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... et al., 2012). Since most electrophysiological and imaging studies of cell body layers (like hippocampal pyramidal cells) are performed in this region, the results may be biased by the inclusion of these injured cells, thus reflecting pathological rather than physiological processes. Indeed, slicing ...
Central Emotional Integration
Central Emotional Integration

... Feeling = conscious sensation mediated by cingulate & frontal cortex. ...
Central Emotional System
Central Emotional System

... Feeling = conscious sensation mediated by cingulate & frontal cortex. ...
Sympathetic - Perkins Science
Sympathetic - Perkins Science

... Both excitatory and inhibitory effects can be produced in different tissues by the same neurotransmitter because different tissues have different receptors. α(alpha) -adrenergic receptors stimulate a rise in cytoplasmic Calcium α1– causes vasoconstriction by increasing Ca2+ α2 – they are activated b ...
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LL2419251928

... Texture analysis refers to a set of processes applied to characterize spatial variations of pixel’s gray levels in an image.Texture analysis which is used to quantify pathological changes that may be undetectable by conventioalMRI techniques,has the potential to detect the subtle changes in tissues ...
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Nervous_system_Tissue_Overview0

...  Anesthesia ****Medical Implication (add to notes): Hard to get antibiotics through BBB so hard to treat brain infections ...
Regulation of Neurosteroid Biosynthesis by Neurotransmitters and
Regulation of Neurosteroid Biosynthesis by Neurotransmitters and

... of sulfated steroids such as ∆5P sulfate (∆5PS) and DHEA sulfate (DHEAS); and sulfatase, which hydrolyzes sulfated steroids to produce unconjugated steroids (Mensah-Nyagan et al. 1999; Mellon and Vaudry 2001). The term neurosteroids has been coined to designate all biologically active steroids synth ...
Inhibitory Neurotransmitters are the nervous system`s “off switches
Inhibitory Neurotransmitters are the nervous system`s “off switches

... and spinal cord. Aspartic acid is the excitatory counterpart to glycine, an inhibitory neurotransmitter. Low levels have been linked to feelings of fatigue and low mood, whereas high levels have been linked to seizures and anxiousness. DOPAC- Dopamine Metabolite After neuronal dopamine is released i ...
Brain Imaging Technologies and Their Applications in Neuroscience
Brain Imaging Technologies and Their Applications in Neuroscience

... produce the signal when exposed to a strong magnetic field. The MRI machine contains the magnet. Structural MRI measures the nuclear magnetic resonance of water protons to create a computerized three-dimensional image of tissues. More specifically, protons in the nuclei of hydrogen atoms in water mo ...
presentation-notes-for-brain-power
presentation-notes-for-brain-power

... Learn the basics of how the brain’s 100 billion nerve cells are born, grow, connect, and function. Neuroanatomy; Cell Communication; Brain Development. ...
Kandel and Schwartz, 4th Edition Principles of Neural Science Chap
Kandel and Schwartz, 4th Edition Principles of Neural Science Chap

... several connected areas of the cortex—where they cause certain populations of cells to discharge. Initially, sensory information is processed in a series of relays, each of which involves more complex information processing than the preceding relay. Sensory fibers project in an orderly pattern from ...
28. Nervous Systems
28. Nervous Systems

... A neuron may receive information from hundreds of other neurons via thousands of synaptic terminals ...
5. Discussion - UvA-DARE - University of Amsterdam
5. Discussion - UvA-DARE - University of Amsterdam

... The last chapter revolved around the question of how a change in brain state, i.e. the difference between wakefulness and being under anesthesia, alters activity patterns of neurons in the primary visual cortex that emerge spontaneously and in response to visual stimuli. Using two-photon calcium ima ...
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Aging brain

Age is a major risk factor for most common neurodegenerative diseases, including Mild cognitive impairment, Alzheimer's disease, cerebrovascular disease, Parkinson's disease and Lou Gehrig's disease. While much research has focused on diseases of aging, there are few informative studies on the molecular biology of the aging brain (usually spelled ageing brain in British English) in the absence of neurodegenerative disease or the neuropsychological profile of healthy older adults. However, research does suggest that the aging process is associated with several structural, chemical, and functional changes in the brain as well as a host of neurocognitive changes. Recent reports in model organisms suggest that as organisms age, there are distinct changes in the expression of genes at the single neuron level. This page is devoted to reviewing the changes associated with healthy aging.
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