Applied Microbiology and Biotechnology
... generated from DB5 when the same primers and conditions were used. For DB5, three individual PCR products of 0.35, 1.35 and 1.5 kb were used to determine the sequence of the 16S rRNA gene. The available information covers the first 700 nucleotides from the 5′-end of the gene, followed by a gap of 14 ...
... generated from DB5 when the same primers and conditions were used. For DB5, three individual PCR products of 0.35, 1.35 and 1.5 kb were used to determine the sequence of the 16S rRNA gene. The available information covers the first 700 nucleotides from the 5′-end of the gene, followed by a gap of 14 ...
origins debate intro
... are the reagents for the start of the next chemical reactions. In this way, the network is self-sustaining. This hypothesis also proposes how complex organic molecules could have built up in large quantity in a small area over time. ...
... are the reagents for the start of the next chemical reactions. In this way, the network is self-sustaining. This hypothesis also proposes how complex organic molecules could have built up in large quantity in a small area over time. ...
pentose phosphate pathway
... • The new reactions provide for a spontaneous pathway (DG negative in the direction of sugar synthesis), and they provide new mechanisms of ...
... • The new reactions provide for a spontaneous pathway (DG negative in the direction of sugar synthesis), and they provide new mechanisms of ...
Computational protein design enables a novel one
... chemicals from common feedstocks, such as glucose, have been constructed in organisms that lack one-carbon anabolic pathways, such as Escherichia coli or Saccharomyces cerevisiae (1–3); however, despite considerable effort, it has been difficult to introduce heterologous one-carbon fixing pathways i ...
... chemicals from common feedstocks, such as glucose, have been constructed in organisms that lack one-carbon anabolic pathways, such as Escherichia coli or Saccharomyces cerevisiae (1–3); however, despite considerable effort, it has been difficult to introduce heterologous one-carbon fixing pathways i ...
Brucella Quorum Sensing: much more than
... (iii) given the enclosed vacuolar space of the intracellular niche of Brucella, the bacteria would not need to produce a large amount of AHL and could control its synthesis and/or stability (see below “the AHL degrading enzymes). 2.2. The AHL-synthase 2.2.1. The LuxI, LuxM/AinS and HdtS families Thr ...
... (iii) given the enclosed vacuolar space of the intracellular niche of Brucella, the bacteria would not need to produce a large amount of AHL and could control its synthesis and/or stability (see below “the AHL degrading enzymes). 2.2. The AHL-synthase 2.2.1. The LuxI, LuxM/AinS and HdtS families Thr ...
della protein function during differential growth - RiuNet
... The plant hormones gibberellins (GAs) regulate multiple processes of plant development, such as seed germination, photomorphogenesis, vegetative growth, and flower and fruit development. Most of this regulation occurs at the transcriptional level, through the activity of the DELLAs, which are nucl ...
... The plant hormones gibberellins (GAs) regulate multiple processes of plant development, such as seed germination, photomorphogenesis, vegetative growth, and flower and fruit development. Most of this regulation occurs at the transcriptional level, through the activity of the DELLAs, which are nucl ...
Gene Section CDC25A (cell division cycle 25A) Atlas of Genetics and Cytogenetics
... The other reported isoform CDC25A2, consists of 484 amino acids with a molecular weight of 54.4 kDa. Both the isoforms have the same N- and C-terminal end, thus expected to have similar catalytic activity. The Nterminal regulatory domain contains several phosphorylation sites and show low sequence h ...
... The other reported isoform CDC25A2, consists of 484 amino acids with a molecular weight of 54.4 kDa. Both the isoforms have the same N- and C-terminal end, thus expected to have similar catalytic activity. The Nterminal regulatory domain contains several phosphorylation sites and show low sequence h ...
Cfe Higher Biology Metabolism and Survival
... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
Bioinformatics information resources and networks
... Ulf Schmitz, Bioinformatics Information Resources and Networks ...
... Ulf Schmitz, Bioinformatics Information Resources and Networks ...
Cfe Higher Biology Metabolism and Survival
... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
... pass through the membrane, for example, a protein channel found in the plasma membrane allows chloride ions (Cl - ) to cross the membrane. • Carrier (pump) proteins - as the name suggests, carrier proteins bind to specific molecules or ions temporarily, enabling them to cross the membrane. This invo ...
Unit 2 - eduBuzz.org
... A catabolic reaction releases energy through the breakdown of a large molecule into smaller units (cellular respiration is a good example of this). An anabolic reaction uses energy to build small molecules into large ones, such as the synthesis of a protein from amino acids. Many of the pathways are ...
... A catabolic reaction releases energy through the breakdown of a large molecule into smaller units (cellular respiration is a good example of this). An anabolic reaction uses energy to build small molecules into large ones, such as the synthesis of a protein from amino acids. Many of the pathways are ...
Yeast Nutrients Make Fermentations Better
... yeast cell. A yeast cell can be thought of as a “bag of enzymes”. Each enzyme catalyzes a different chemical reaction. Each enzyme also has specific mineral requirements for optimum performance. These chemical reactions produce alcohol, flavor compounds, energy for growth, cell wall compounds, and s ...
... yeast cell. A yeast cell can be thought of as a “bag of enzymes”. Each enzyme catalyzes a different chemical reaction. Each enzyme also has specific mineral requirements for optimum performance. These chemical reactions produce alcohol, flavor compounds, energy for growth, cell wall compounds, and s ...
UNIT – I: NUCLEIC ACID AND PROTEIN SYNTHESIS AND
... used in the development and functioning of all known living organisms. The main role of DNA molecules is the long-term storage of information and DNA is often compared to a set of blueprints, since it contains the instructions needed to construct other components of cells, such as proteins and RNA m ...
... used in the development and functioning of all known living organisms. The main role of DNA molecules is the long-term storage of information and DNA is often compared to a set of blueprints, since it contains the instructions needed to construct other components of cells, such as proteins and RNA m ...
Biochemical and Molecular Characterization of the Chicken
... Biosystems Ltd., Kent, UK). The column was washed with '~100 ml of buffer B-10; the 23-kD protein was collected in the non-adsorbed column fractions. Ammonium sulfate was added to the non-adsorbed fractions enriched in the 23-kD protein to a final concentration of 20% saturation and mixed briefly, T ...
... Biosystems Ltd., Kent, UK). The column was washed with '~100 ml of buffer B-10; the 23-kD protein was collected in the non-adsorbed column fractions. Ammonium sulfate was added to the non-adsorbed fractions enriched in the 23-kD protein to a final concentration of 20% saturation and mixed briefly, T ...
Threading-based Protein Structure Prediction
... from non-coding DNA • Search-by-homology: find genes by homology (after translation) to proteins • State-of-the-art systems for gene finding ...
... from non-coding DNA • Search-by-homology: find genes by homology (after translation) to proteins • State-of-the-art systems for gene finding ...
BIOINFORMATICS ORIGINAL PAPER Going from where to why—interpretable prediction of protein subcellular localization
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
local copy pdf
... Creation scientist. Jack Szostak is working to recreate a recipe that transformed chemistry into biology. ...
... Creation scientist. Jack Szostak is working to recreate a recipe that transformed chemistry into biology. ...
regulation of mammalian acetyl
... The isolation and characterization of the various phosphopeptides of ACC-α that can be phosphorylated by different protein kinases in vitro and in vivo (32, 35, 67) made it possible to identify the phosphorylation sites for specific protein kinases that control ACC activity under different physiolog ...
... The isolation and characterization of the various phosphopeptides of ACC-α that can be phosphorylated by different protein kinases in vitro and in vivo (32, 35, 67) made it possible to identify the phosphorylation sites for specific protein kinases that control ACC activity under different physiolog ...
Metabolic decision making by protein-metabolite - ETH E
... (chapters 5 to 7) enzyme regulation. In chapter 2, we review our current understanding of the role of transcription in regulating microbial fluxes, focusing on central metabolism. We highlight recent works that investigated the impact of altering enzyme abundance, for example th ...
... (chapters 5 to 7) enzyme regulation. In chapter 2, we review our current understanding of the role of transcription in regulating microbial fluxes, focusing on central metabolism. We highlight recent works that investigated the impact of altering enzyme abundance, for example th ...
Streptococcus pneumoniae Senses a Human-like Sialic Acid
... shown that, after Sia uptake, Neu5Ac and Neu5Gc are metabo310 Cell Host & Microbe 20, 307–317, September 14, 2016 ...
... shown that, after Sia uptake, Neu5Ac and Neu5Gc are metabo310 Cell Host & Microbe 20, 307–317, September 14, 2016 ...
A futile metabolic cycle activated in adipocytes by - Zen-Bio
... Obesity and type 2 diabetes are epidemic in industrialized societies1. Metabolic dysregulation is a hallmark of diabetes, but for many years the fat cell was viewed largely as a depository for fuel in the form of fatty acids incorporated into triglyceride (TG)2. More recently, the adipocyte has been ...
... Obesity and type 2 diabetes are epidemic in industrialized societies1. Metabolic dysregulation is a hallmark of diabetes, but for many years the fat cell was viewed largely as a depository for fuel in the form of fatty acids incorporated into triglyceride (TG)2. More recently, the adipocyte has been ...
Going from where to why—interpretable
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
... subcellular localization that addresses these issues. Due to its simple architecture, YLoc can identify the relevant features of a protein sequence contributing to its subcellular localization, e.g. localization signals or motifs relevant to protein sorting. We present several example applications w ...
Biotechnology for Biofuels
... Cellulose is the most abundant renewable feedstock on earth for biofuel production [1]. However, the economic feasibility and sustainability of cellulosic biofuels are limited by the inefficient breakdown of recalcitrant cellulose fibers into sugars [2] and their fermentation into biofuels and other ...
... Cellulose is the most abundant renewable feedstock on earth for biofuel production [1]. However, the economic feasibility and sustainability of cellulosic biofuels are limited by the inefficient breakdown of recalcitrant cellulose fibers into sugars [2] and their fermentation into biofuels and other ...
Authors` version - The Computable Plant
... Systems biology may be broadly defined as the integration of diverse data into useful biological models that allow scientists to easily observe complex cellular behaviors and to predict the outcomes of metabolic and genetic perturbations. As a first step towards the elucidation of the systems biolog ...
... Systems biology may be broadly defined as the integration of diverse data into useful biological models that allow scientists to easily observe complex cellular behaviors and to predict the outcomes of metabolic and genetic perturbations. As a first step towards the elucidation of the systems biolog ...
Gene regulatory network
A gene regulatory network or genetic regulatory network (GRN) is a collection of regulators thatinteract with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins.The regulator can be DNA, RNA, protein and their complex. The interaction can be direct or indirect (through their transcribed RNA or translated protein).In general, each mRNA molecule goes on to make a specific protein (or set of proteins). In some cases this protein will be structural, and will accumulate at the cell membrane or within the cell to give it particular structural properties. In other cases the protein will be an enzyme, i.e., a micro-machine that catalyses a certain reaction, such as the breakdown of a food source or toxin. Some proteins though serve only to activate other genes, and these are the transcription factors that are the main players in regulatory networks or cascades. By binding to the promoter region at the start of other genes they turn them on, initiating the production of another protein, and so on. Some transcription factors are inhibitory.In single-celled organisms, regulatory networks respond to the external environment, optimising the cell at a given time for survival in this environment. Thus a yeast cell, finding itself in a sugar solution, will turn on genes to make enzymes that process the sugar to alcohol. This process, which we associate with wine-making, is how the yeast cell makes its living, gaining energy to multiply, which under normal circumstances would enhance its survival prospects.In multicellular animals the same principle has been put in the service of gene cascades that control body-shape. Each time a cell divides, two cells result which, although they contain the same genome in full, can differ in which genes are turned on and making proteins. Sometimes a 'self-sustaining feedback loop' ensures that a cell maintains its identity and passes it on. Less understood is the mechanism of epigenetics by which chromatin modification may provide cellular memory by blocking or allowing transcription. A major feature of multicellular animals is the use of morphogen gradients, which in effect provide a positioning system that tells a cell where in the body it is, and hence what sort of cell to become. A gene that is turned on in one cell may make a product that leaves the cell and diffuses through adjacent cells, entering them and turning on genes only when it is present above a certain threshold level. These cells are thus induced into a new fate, and may even generate other morphogens that signal back to the original cell. Over longer distances morphogens may use the active process of signal transduction. Such signalling controls embryogenesis, the building of a body plan from scratch through a series of sequential steps. They also control and maintain adult bodies through feedback processes, and the loss of such feedback because of a mutation can be responsible for the cell proliferation that is seen in cancer. In parallel with this process of building structure, the gene cascade turns on genes that make structural proteins that give each cell the physical properties it needs.It has been suggested that, because biological molecular interactions are intrinsically stochastic, gene networks are the result of cellular processes and not their cause (i.e. cellular Darwinism). However, recent experimental evidence has favored the attractor view of cell fates.