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The cDNA-deduced Amino Acid Sequence for
The cDNA-deduced Amino Acid Sequence for

... within the inner root sheath of hair follicles and is similar, or identical, to a protein present in the hair medulla. In situ hybridization studies have shown that trichohyalin is a very early differentiation marker in both tissues and that in each case the trichohyalin mRNA is expressed from the s ...
Diapositive 1 - International QSAR Foundation
Diapositive 1 - International QSAR Foundation

...  in case of reparation of oxidative DNA damage : escape to the genotoxicity screening  some events not directly related to DNA damage may occur before reparation : ...
How to use KAIKObase: An integrated silkworm genome database
How to use KAIKObase: An integrated silkworm genome database

... The top page provides access to silkworm genome information. 1)  Chromosome select: Two choices are available for the genome maps – the PGmap can be accessed by clicking the chromosome number after clicking PGmap (colored pink) and the UnifiedMap by clicking the chromosome number after clicking Unif ...
Gene Section SRXN1 (sulfiredoxin 1) Atlas of Genetics and Cytogenetics
Gene Section SRXN1 (sulfiredoxin 1) Atlas of Genetics and Cytogenetics

... In adult, Srx protein was found in internal organs such as mouse liver and kidney. Expression pattern of Srx in embryonic development is not clear. Transcriptional regulation of Srx expression is mainly mediated through AP-1 and/or Nrf-2 activation (Jeong et al., 2012). In yeast, it may also be nega ...
Exam - Vcaa
Exam - Vcaa

... A. Ribonuclease has the effect of turning on the casein gene. B. Casein is a repressor protein for milk production in mammals. C. The hormone prolactin allows for the expression of the casein gene. D. Mammals produce milk only in the absence of the hormone prolactin. Question 25 Plasmids of bacteria ...
Slide
Slide

... How we obtain the sequence of nucleotides of a species ...
Speaker: Dr. Arnob Dutta Title: Multiple mechanisms to regulate the
Speaker: Dr. Arnob Dutta Title: Multiple mechanisms to regulate the

... Title: Multiple mechanisms to regulate the Swi/Snf chromatin remodeler Abstract: The Swi/Snf chromatin remodeling complex functions to alter nucleosome positions by either sliding nucleosomes on DNA or the eviction of histones. The presence of histone acetylation and activator dependent recruitment ...
Folie 1 - uni
Folie 1 - uni

... • methods are available for efficient analysis of transcription patterns of multiple genes • because proteins ‘turn over’ at different rates, it is also necessary to measure proteins directly • the distribution of expressed protein levels is a kinetic balance between rates of protein synthesis and d ...
The Old World monkey DAZ (Deleted in
The Old World monkey DAZ (Deleted in

... The cynDAZ cDNA shares high homology with the cynDAZL1 cDNA, but is much larger and has a more complex structure. It covers 4490 nucleotides with 13 nucleotides for the 5′-UTR and 2032 nucleotides forming the 3′-UTR. Inspection of the ORF, extending from +1 to 2454, revealed the presence of a struct ...
HEMOGLOBINOPATHY412 KB
HEMOGLOBINOPATHY412 KB

... HEMOGLOBINOPATHY • Mutations in the genes that encode the α or β subunits of Hb potentially can affect its biological function • More than 800 known mutant human Hbs are both extremely rare and benign, with no clinical abnormalities • When a mutation compromises bilogic function hemoglobinopathy ...
Variation in biological properties of cauliflower mosaic virus clones
Variation in biological properties of cauliflower mosaic virus clones

... 60 bp. Most CaMV clones studied remained biologically stable producing similar symptoms during subsequent passages. However, one clone (11/3-7) produced two new biotypes during its first passage suggesting that it was relatively unstable. Our results show that wild-type populations of CaMV contain a ...
gmod-arthrobase-07dec - IUBio Archive for Biology
gmod-arthrobase-07dec - IUBio Archive for Biology

... • CV: Controlled vocabularies and ontologies • Sequence: Biological sequences and objects which can be localized on them • Companalysis: Adjunct to sequence module for insilico analysis • Map: Adjunct to sequence module for non-sequence localization ...
Shedding Light on the Bioluminescence “Paradox”
Shedding Light on the Bioluminescence “Paradox”

... is often argued that luciferase has a higher affinity for oxygen than respiration does, and therefore might be useful in decreasing ambient O2. However this is based on assumptions that V. fischeri possesses a low-O2-affinity CyoABCDtype terminal oxidase and on measurements of respiration in cells g ...
Choreography of Transcriptomes and Lipidomes of
Choreography of Transcriptomes and Lipidomes of

... For those clusters predominated by unknown genes, the second largest functional category was designated as the primary functional genes for a given cluster (Figure 1B). In cluster C1, 42% genes encoded components of the photosynthetic apparatuses, such as light-harvesting complex and photosystem rea ...
Identification of Plant Virus Movement-Host Protein
Identification of Plant Virus Movement-Host Protein

... plasmodesmata between sieve elements and the vascular parenchyma in minor veins to gain direct access to the phloem, rather then entering the com ­ panion cells. A family of key chaperones was pos­ tulated to be involved in macrom olecular transport in the phloem parenchyma - companion cell sieve el ...
Identification of Plant Virus Movement
Identification of Plant Virus Movement

... plasmodesmata between sieve elements and the vascular parenchyma in minor veins to gain direct access to the phloem, rather then entering the com ­ panion cells. A family of key chaperones was pos­ tulated to be involved in macrom olecular transport in the phloem parenchyma - companion cell sieve el ...
Molecular analysis of extracellular-superoxide dismutase
Molecular analysis of extracellular-superoxide dismutase

... (Karlson et al., 1988; Adachi and Marklund, 1989). In the vascular system, ECSOD binds on the surface of endothelial cells through the heparan sulfate proteoglycan, and eliminates the oxygen radicals from the NADPH dependent oxidative system from the neutrophils. Since the EC-SOD mainly exists on th ...
The arbuscular mycorrhizal fungal protein glomalin is
The arbuscular mycorrhizal fungal protein glomalin is

... and Cryptococcus neoformans. Sequence analysis of the fulllength GiHsp 60 cDNA revealed that it contains an ORF encoding a protein of 590 amino acid length. Use of PCR primers flanking the GiHsp 60 ORF on genomic DNA resulted in the isolation of a genomic fragment, 2047 bp in length, suggesting the ...
Inhibition of the p53 tumor suppressor by MDM2
Inhibition of the p53 tumor suppressor by MDM2

... The p53 tumor suppressor p53 is a highly specialized protein designated with preventing cancerous tumor growth in cells. The P53 protein is classified as a tumor suppressor and is tasked with keeping the genomic stability of cells by inducing apoptosis and cell cycle arrest in cancerous cells (Frum, ...
the cortex adhaerens mosaic of lens fiber cells
the cortex adhaerens mosaic of lens fiber cells

... The physical laws of the vision process require transparency and homogeneity of the lens body. Therefore, the tight package of the lens fibers, with frequent and often regularly spaced interdigitations, as well as the high concentration and homogenous distribution of cytoplasmic proteins, including ...
A Novel Mutation of the VMD2 Gene in a Chinese Family with Best
A Novel Mutation of the VMD2 Gene in a Chinese Family with Best

... acids. The mutations mainly cluster in or near exons 2, 4, 6 and 8, which are the regions of predicted transmembrane domains. This suggests these regions may have an important functional role. Bestrophin, which has an approximate mass of 68 kDa, shares a homology with the C. elegans RFP gene family, ...
Use of Amino Acids as Inducers for High
Use of Amino Acids as Inducers for High

... converted into a bioreactor producing only a single protein of interest by using an ACA-less mRNA for the protein. In this single-protein production (SPP) system, we engineered MazF by replacing two tryptophan residues in positions 14 and 83 with Phe (W14F) and Leu (W83L), respectively. Upon the add ...
Database Searching
Database Searching

... Homology and Analogy The essence of sequence analysis is the inference of homology.  Homology is not a measure of similarity, but an absolute statement that sequences have a divergent rather than a convergent relationship.  Thus, phrases that quantify homology are meaningless. ...
Milestone10
Milestone10

... i.e., yeast microarray data was clustered and these 21 genes clustered in the same group. Again, we extracted the upstream sequences for each of these 21 genes. Download the following file: http://cs.wellesley.edu/~cs303/assignments/M10/ECB.txt You should submit these 21 sequences to the Gibbs Motif ...
Controlling Gene Expression in Bacteria
Controlling Gene Expression in Bacteria

... cells all the time. These continually expressed genes are called constitutive genes.  Other genes are only needed by certain cells or at specific times. The expression of these inducible genes is tightly controlled.  For example, pancreas beta cells make the protein insulin by expressing the insul ...
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Endogenous retrovirus



Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.
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