DNA Specificity of the Bicoid Activator Protein Is Determined by
... “helix swap” experiments showed that Bicoid’s DNA specificity is determined by recognition helix amino acid 9. Our results also suggest that for Antp class and other closely related homeoproteins, DNA specificity inheres in residue 9. Results DNA-Bound Bicoid Activates Gene Expression We tested whet ...
... “helix swap” experiments showed that Bicoid’s DNA specificity is determined by recognition helix amino acid 9. Our results also suggest that for Antp class and other closely related homeoproteins, DNA specificity inheres in residue 9. Results DNA-Bound Bicoid Activates Gene Expression We tested whet ...
Molecular Abnormality of Erythrocyte Pyruvate
... final osmolarity to 290 mOsm/kg, in the presence or absence of the indicated additive. Values shown are the negative In of the calculated intracellular K+ concentration as a function of time. ...
... final osmolarity to 290 mOsm/kg, in the presence or absence of the indicated additive. Values shown are the negative In of the calculated intracellular K+ concentration as a function of time. ...
University of Groningen Structure and mechanism of the ECF
... Vitamin transport in Gram-positive prokaryotes Although a number of reports on vitamin transport by prokaryotes have been published in the past fifty years, detailed biochemical- and mechanistic studies are scarce. Much of this work for Gram-positive bacteria has been performed by Gary Henderson et ...
... Vitamin transport in Gram-positive prokaryotes Although a number of reports on vitamin transport by prokaryotes have been published in the past fifty years, detailed biochemical- and mechanistic studies are scarce. Much of this work for Gram-positive bacteria has been performed by Gary Henderson et ...
Presentation
... • Although the steady state of the tissue cells is disturbed, there is still a lot of cell loss. – Cancer stem cells exist that may be a small minority of the population. They may not be the targeted by the chosen therapy. Rapid tumor regression may not mean much if it represents loss of the non-ste ...
... • Although the steady state of the tissue cells is disturbed, there is still a lot of cell loss. – Cancer stem cells exist that may be a small minority of the population. They may not be the targeted by the chosen therapy. Rapid tumor regression may not mean much if it represents loss of the non-ste ...
Text Book of Molecular Biology
... P129 fig 11-6 D 2. The ‘beads on a string’ structure is organized into chromatin/chromosome 3. The mitotic chromosome has one centromere and two telomeres. P129 fig 6-12 The ends of the linear chromosomal DNA are protected from degradation and gradual shortening by the telomeres. The telomere consi ...
... P129 fig 11-6 D 2. The ‘beads on a string’ structure is organized into chromatin/chromosome 3. The mitotic chromosome has one centromere and two telomeres. P129 fig 6-12 The ends of the linear chromosomal DNA are protected from degradation and gradual shortening by the telomeres. The telomere consi ...
Resistance to the Pseudomonas syringae Effector
... 2004) for mutants susceptible to DC3000(hopA1) (see “Materials and Methods”). We screened approximately 25,000 M2 plants representing 1,100 M1 plants from 67 different pools by dip inoculation with DC3000(hopA1). Of 138 M2 individuals that were scored as susceptible after the first screen, we identi ...
... 2004) for mutants susceptible to DC3000(hopA1) (see “Materials and Methods”). We screened approximately 25,000 M2 plants representing 1,100 M1 plants from 67 different pools by dip inoculation with DC3000(hopA1). Of 138 M2 individuals that were scored as susceptible after the first screen, we identi ...
Green Fluorescent Protein (GFP) Purification Kit
... Is Finding a Needle in a Hay Stack Easier When it Glows? This laboratory activity is designed to follow Biotechnology Explorer Kit 1, “Bacterial Transformation—the pGLO System” (catalog number 166-0003-EDU). Students begin this activity with the bacteria they genetically transformed using the plasm ...
... Is Finding a Needle in a Hay Stack Easier When it Glows? This laboratory activity is designed to follow Biotechnology Explorer Kit 1, “Bacterial Transformation—the pGLO System” (catalog number 166-0003-EDU). Students begin this activity with the bacteria they genetically transformed using the plasm ...
A. Introduction
... This is the portion of the fundamental niche actually used by an organism and is determined by physical factors and interactions with other organisms. 3. Resource Partitioning If two similar species are living in the same area, then their niches are expected to be different in some way. These specie ...
... This is the portion of the fundamental niche actually used by an organism and is determined by physical factors and interactions with other organisms. 3. Resource Partitioning If two similar species are living in the same area, then their niches are expected to be different in some way. These specie ...
1. INTRODUCTION 1.1 THE ARACHIDONIC ACID - diss.fu
... hydroperoxide tone (Ochi et al., 1983; Weitzel and Wendel, 1993). The 15-LOX requires calcium for the translocation of the enzyme to membranes, however, the activity is calciumindependent (Watson and Doherty, 1994; Brinckmann et al., 1998; Hoffman et al., 1988). The 15-LOX activity is dependent on t ...
... hydroperoxide tone (Ochi et al., 1983; Weitzel and Wendel, 1993). The 15-LOX requires calcium for the translocation of the enzyme to membranes, however, the activity is calciumindependent (Watson and Doherty, 1994; Brinckmann et al., 1998; Hoffman et al., 1988). The 15-LOX activity is dependent on t ...
ABC Pumps and Their Role in Active Drug Transport
... restrictive and selective physiological lines of defense of the organism. Although several parameters such as LogP, LogD and Ka have been extensively employed for determining drug bioavailability, the active transports, present in these biological barriers, play an important role for dosing and limi ...
... restrictive and selective physiological lines of defense of the organism. Although several parameters such as LogP, LogD and Ka have been extensively employed for determining drug bioavailability, the active transports, present in these biological barriers, play an important role for dosing and limi ...
Custom RT-qPCR Assays and Panels for any Human, Mouse, or Rat
... 9/8/2015)) and corresponding patent claims outside the United States. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser’s own internal research. The right to use this product ...
... 9/8/2015)) and corresponding patent claims outside the United States. The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser’s own internal research. The right to use this product ...
Complementary DNA Sequence of a Human Cytoplasmic Actin
... muscle tissue. The other two, /3- and y-a&in, are called cytoplasmic actins and are typical of non-muscle tissue (Vandekerckhove & Weber, 19786). In the human genome. there are more than 20 actin genes as estimated by hybridization studies using cloned complementary DNA probes derived from mouse or ...
... muscle tissue. The other two, /3- and y-a&in, are called cytoplasmic actins and are typical of non-muscle tissue (Vandekerckhove & Weber, 19786). In the human genome. there are more than 20 actin genes as estimated by hybridization studies using cloned complementary DNA probes derived from mouse or ...
Primary and secondary metabolism, and post
... represented are discussed in terms of their annotated functional classes. An average of 1.2 proteins per gene was observed, indicating extensive posttranslational regulation. Examples of modification by N-acetylation, adenylylation and proteolytic processing were characterized using mass spectrometr ...
... represented are discussed in terms of their annotated functional classes. An average of 1.2 proteins per gene was observed, indicating extensive posttranslational regulation. Examples of modification by N-acetylation, adenylylation and proteolytic processing were characterized using mass spectrometr ...
En/Spm-LIKE TRANSPOSONS IN POACEAE SPECIES
... a given cereal’s nuclear genome) [1]. From the investigation of the Drosophila genomes, it is known that TE can give rise to significant genomic changes by creating mutations, altering gene expression, conducting telomeric function, and promoting chromosomal aberrations [2-4]. TE was divided into tw ...
... a given cereal’s nuclear genome) [1]. From the investigation of the Drosophila genomes, it is known that TE can give rise to significant genomic changes by creating mutations, altering gene expression, conducting telomeric function, and promoting chromosomal aberrations [2-4]. TE was divided into tw ...
Document
... Protein fingerprinting is a technique used to compare proteins from different species. Species which are closely related have similar protein fingerprints. Samples of protein are extracted from cells, separated by gel electrophoresis, then stained to make each type of protein show up as a band. The ...
... Protein fingerprinting is a technique used to compare proteins from different species. Species which are closely related have similar protein fingerprints. Samples of protein are extracted from cells, separated by gel electrophoresis, then stained to make each type of protein show up as a band. The ...
A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is
... the Rb pathway, RIZ may play an important role in the pathogenesis of human cancer. Interestingly, RIZ produces 2 different gene products, a full-length RIZ1 and a short-form RIZ2 lacking a PR domain at the amino-terminus, which is generated by an alternative transcript derived from an internal prom ...
... the Rb pathway, RIZ may play an important role in the pathogenesis of human cancer. Interestingly, RIZ produces 2 different gene products, a full-length RIZ1 and a short-form RIZ2 lacking a PR domain at the amino-terminus, which is generated by an alternative transcript derived from an internal prom ...
Additional File 1
... HumanNet. Results for matching disjoint KEGG sets and time-split GO sets are shown on the left and right, respectively. ...
... HumanNet. Results for matching disjoint KEGG sets and time-split GO sets are shown on the left and right, respectively. ...
AP Biology Concept Outline
... Enduring understanding 1.D: The origin of living systems is explained by natural processes. The process of evolution explains the diversity and unity of life. A number of experimental investigations have provided evidence that the conditions early in the Earth’s history provided an environment capab ...
... Enduring understanding 1.D: The origin of living systems is explained by natural processes. The process of evolution explains the diversity and unity of life. A number of experimental investigations have provided evidence that the conditions early in the Earth’s history provided an environment capab ...
molecular phylogeny of the haplosporidia based on
... groups to the relative inclusion and exclusion of potentially phylogenetically informative sites. In the first series of analyses, which concerned the relative position of Haplosporidia within Eukaryota, it was noted that there were large inserted regions in the SSU rDNA sequences of some taxa, incl ...
... groups to the relative inclusion and exclusion of potentially phylogenetically informative sites. In the first series of analyses, which concerned the relative position of Haplosporidia within Eukaryota, it was noted that there were large inserted regions in the SSU rDNA sequences of some taxa, incl ...
Osmoadaptative Strategy and Its Molecular
... compatible solute. Glycerol is one of the cheapest and simplest osmolytes to produce, but is rarely found in other halophiles studied to date, possibly because of its high diffusion rate through standard cell membranes (Oren 1999). Yeasts and Dunaliella have developed mechanisms to increase glycerol ...
... compatible solute. Glycerol is one of the cheapest and simplest osmolytes to produce, but is rarely found in other halophiles studied to date, possibly because of its high diffusion rate through standard cell membranes (Oren 1999). Yeasts and Dunaliella have developed mechanisms to increase glycerol ...
File
... The height of a stack of letters in a logo indicates the predictive power of that stack (determined statistically). If the stack is tall, we can be more confident in predicting what base will be in that position if a new sequence is added to the logo. For example, at position 2, all 10 sequences ha ...
... The height of a stack of letters in a logo indicates the predictive power of that stack (determined statistically). If the stack is tall, we can be more confident in predicting what base will be in that position if a new sequence is added to the logo. For example, at position 2, all 10 sequences ha ...
The Senescence?Related Mitochondrial/Oxidative Stress Pathway
... occur within differentiated somatic cells during aging [29]. Indeed, transcriptome analysis of human skin aging has identified specific alterations in pathways related to mitochondria and oxidative stress [30]. mtDNA undergoes a high rate of mutation, due to elevated ROS levels and the lack of histo ...
... occur within differentiated somatic cells during aging [29]. Indeed, transcriptome analysis of human skin aging has identified specific alterations in pathways related to mitochondria and oxidative stress [30]. mtDNA undergoes a high rate of mutation, due to elevated ROS levels and the lack of histo ...
Transcriptomic analysis reveals metabolic switches and
... others (Table 2 and Table S1). These results suggest the relevance of epigenetic regulation in T. cruzi life cycle. Also amino acid activation (synthesis of aminoacyl-tRNAs) and other proteins related to translation machinery appear to be relevant in driving changes through the cycle (Table S1). Met ...
... others (Table 2 and Table S1). These results suggest the relevance of epigenetic regulation in T. cruzi life cycle. Also amino acid activation (synthesis of aminoacyl-tRNAs) and other proteins related to translation machinery appear to be relevant in driving changes through the cycle (Table S1). Met ...
IOTest CD25-APC-Alexa Fluor 700
... The high affinity IL-2 receptor (IL-2R) is a trimeric complex composed of three polypeptides chains, α (IL-2Rα, Tac, p55, or CD25), β (IL-2Rβ, p75, or CD122), and γ (IL2Rγ or p64). T lymphocytes express an intermediate-affinity IL-2 receptor that comprises β /γ or α/γ chain complex. IL-2Rβ and IL-2R ...
... The high affinity IL-2 receptor (IL-2R) is a trimeric complex composed of three polypeptides chains, α (IL-2Rα, Tac, p55, or CD25), β (IL-2Rβ, p75, or CD122), and γ (IL2Rγ or p64). T lymphocytes express an intermediate-affinity IL-2 receptor that comprises β /γ or α/γ chain complex. IL-2Rβ and IL-2R ...
Cytochrome P450 - Spektrum der Wissenschaft
... Genetically engineered microorganisms are being increasingly used for the industrial production of complicated chemical compounds such as steroids; however, there have been few reports on the use of the fission yeast Schizosaccharomyces pombe for this purpose. Mitochondrial cytochrome P450 enzymes p ...
... Genetically engineered microorganisms are being increasingly used for the industrial production of complicated chemical compounds such as steroids; however, there have been few reports on the use of the fission yeast Schizosaccharomyces pombe for this purpose. Mitochondrial cytochrome P450 enzymes p ...
Endogenous retrovirus
Endogenous retroviruses (ERVs) are endogenous viral elements in the genome that closely resemble and can be derived from retroviruses. They are abundant in the genomes of jawed vertebrates, and they comprise up to 5–8% of the human genome (lower estimates of ~1%). ERVs are a subclass of a type of gene called a transposon, which can be packaged and moved within the genome to serve a vital role in gene expression and in regulation. Researchers have suggested that retroviruses evolved from a type of transposable gene called a retrotransposon, which includes ERVs; these genes can mutate and instead of moving to another location in the genome they can become exogenous or pathogenic. This means that all ERVs may not have originated as an insertion by a retrovirus but that some may have been the source for the genetic information in the retroviruses they resemble.