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Chapter 12 Lecture Notes: Metabolism – Enzyme and Gene
Chapter 12 Lecture Notes: Metabolism – Enzyme and Gene

... (1) small molecule (corepressor) has to bind repressor for it to be active (able to repress); if the small molecule is not present then the repressor is inactive (and unable to repress) à TRANSCRIPTION OCCURS (2) typically for anabolic pathways where corepressor is end product 2. positive control = ...
STUDY GUIDE SEMESTER 2 EXAM 4 Dr. Marks Name: Class
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Show DNA to Protein HC
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... – missense mutations no change in amino acid(s) – nonsense mutations changes amino acid and therefore protein • Two types of Point Mutations – Base pair substitutions replacement of nucleotide – Insertions and Deletions -additions or losses of one or more nucleotides • Frameshift mutation - occurs w ...
Poster
Poster

... in the nucleus of all eukaryotic cells and is one of the most important enzymes in our body. Pol II has twelve protein subunits, which also makes it one of the largest molecules. Its function is to surround the DNA, unwind it, separate it into two strands, and use the DNA template strand to create a ...
DNA Replication vs protein synthesis and transcription vs translation
DNA Replication vs protein synthesis and transcription vs translation

... ...
Model Description Sheet
Model Description Sheet

... share a significant genetic commonality. It has been shown that many breast cancer patients test positive for high levels of Estrogen Receptor (ERα), a protein that regulates the differentiation and maintenance of neural, skeletal, cardiovascular, and reproductive tissues in their cells. ERα aids in ...
Chapter 13
Chapter 13

... It is advantageous to have the potential to utilize other sugars (carbon sources), but want to only synthesize the proteins necessary for utilization of these sugars only when glucose is absent & these specific sugars are present. This is accomplished by regulating the transcription of genes that co ...
What is latency? - California State University, Fullerton
What is latency? - California State University, Fullerton

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Gene Section POU6F2 (POU domain, class 6, transcription factor 2)
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PROTEIN SYNTHESIS
PROTEIN SYNTHESIS

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Microbiology Study Guide – Exam #2
Microbiology Study Guide – Exam #2

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Notes (other NGS applications)

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video slide - Greensburg
video slide - Greensburg

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DNA-drug interactions and charge transfer processes in DNA.
DNA-drug interactions and charge transfer processes in DNA.

... http://staff.science.nus.edu.sg/~chmxqh/. ...
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CH 17 CLICKER QUESTIONS
CH 17 CLICKER QUESTIONS

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Chapter 2
Chapter 2

... Aminoacyl-tRNA synthetase is an enzyme whose function is to ___________. To do so, it binds a molecule of amino acid and a molecule of ___________. After dephosphorylation, which two molecules are joined? For the appropriate tRNA to be joined to the amino acid, what must occur? © 2011 Pearson Educat ...
Protein Synthesis
Protein Synthesis

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Lecture Notes

... Zn fingers bind DNA and RNA Zn coordination is via 2 His and 2 Cys in the first class of Zn fingers discovered (C2H2 fingers) C2C2 versions also exist, as do C6 di-Zn2+-binding proteins. Zn fingers are usually modules of larger proteins. Proteins with as many as 37 Zn fingers are known. Their role ...
ppt from class - Pingry School
ppt from class - Pingry School

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Protein Synthesis
Protein Synthesis

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Chapter 17 Presentation
Chapter 17 Presentation

... In prokaryotes transcription proceeds through a DNA sequence that functions as a termination signal causing the polymerase to detach from the DNA. This release of the transcript makes it immediately available for use as mRNA. ...
What is RNA, and How Does it Differ from DNA?
What is RNA, and How Does it Differ from DNA?

... – Change in amino-acid sequence may or may not change function of protein; typically involves changes in shape or charge – Point mutations: change in one base (often random; mutation rates can be increased by mutagens) • If wobble effect, no change in amino acid • Enzymes repair mutations at given r ...
发现次级代谢途径特异性转录调控因子
发现次级代谢途径特异性转录调控因子

... Figure A demonstrates that binding ability relies on the DNA-binding domain, and is independent of the PAS domain. Figure B demonstrates that truncated forms of the protein have significantly higher affinity. ...
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Transcriptional regulation

In molecular biology and genetics, transcriptional regulation is the means by which a cell regulates the conversion of DNA to RNA (transcription), thereby orchestrating gene activity. A single gene can be regulated in a range of ways, from altering the number of copies of RNA that are transcribed, to the temporal control of when the gene is transcribed. This control allows the cell or organism to respond to a variety of intra- and extracellular signals and thus mount a response. Some examples of this include producing the mRNA that encode enzymes to adapt to a change in a food source, producing the gene products involved in cell cycle specific activities, and producing the gene products responsible for cellular differentiation in higher eukaryotes.The regulation of transcription is a vital process in all living organisms. It is orchestrated by transcription factors and other proteins working in concert to finely tune the amount of RNA being produced through a variety of mechanisms. Prokaryotic organisms and eukaryotic organisms have very different strategies of accomplishing control over transcription, but some important features remain conserved between the two. Most importantly is the idea of combinatorial control, which is that any given gene is likely controlled by a specific combination of factors to control transcription. In a hypothetical example, the factors A and B might regulate a distinct set of genes from the combination of factors A and C. This combinatorial nature extends to complexes of far more than two proteins, and allows a very small subset (less than 10%) of the genome to control the transcriptional program of the entire cell.
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