Palladium(II)-Catalyzed Oxidative Cyclization Strategies Andreas K. Å. Persson
... The use of transition metal catalysts has proven to be one of the most diverse tools for the mild and selective formation of carbon-carbon bonds. In particular palladium-catalyzed cross-coupling reactions have revolutionized the field. The main focus of this thesis has been directed towards preparat ...
... The use of transition metal catalysts has proven to be one of the most diverse tools for the mild and selective formation of carbon-carbon bonds. In particular palladium-catalyzed cross-coupling reactions have revolutionized the field. The main focus of this thesis has been directed towards preparat ...
Enol esters: Versatile substrates in synthesis of fine and specialty
... 2. Asymmetric hydroformylation of enol esters ................................................................................. 6 2.2. AHF/ Wittig tandem process involving enol esters ................................................................. 7 3. Asymmetric epoxidation of (Z)-enol esters ... ...
... 2. Asymmetric hydroformylation of enol esters ................................................................................. 6 2.2. AHF/ Wittig tandem process involving enol esters ................................................................. 7 3. Asymmetric epoxidation of (Z)-enol esters ... ...
Full-Text PDF
... mol % of tetrakis(acetonitrile)copper(I) triflate was able to efficiently catalyze the transformation of phenol 1 to the corresponding phenyl acetate 2 in 3 min and in quantitative yield. the model substrate and acetic anhydride (4 equivalents) as the acetylation agent, we found that 1 the model ...
... mol % of tetrakis(acetonitrile)copper(I) triflate was able to efficiently catalyze the transformation of phenol 1 to the corresponding phenyl acetate 2 in 3 min and in quantitative yield. the model substrate and acetic anhydride (4 equivalents) as the acetylation agent, we found that 1 the model ...
Organic Chemistry II Introduction
... Thiols do not form H-bonds (EN of S is low) Alcohols and phenols are weakly basic Alcohols and phenols are weakly acidic Phenols and Thiols are more acidic than water ...
... Thiols do not form H-bonds (EN of S is low) Alcohols and phenols are weakly basic Alcohols and phenols are weakly acidic Phenols and Thiols are more acidic than water ...
Graphene-Catalyzed Direct Friedel–Crafts Alkylation Reactions
... slightly acidic nature of the GO carbocatalyst, and no changes in the acidity after the reaction.48 (5) EDXS analysis (energydispersive X-ray spectroscopy) of the GO material before the reaction showed C/O atomic ratio of 1.95, which increased to C/O atomic ratio of 3.46 after the reaction, indicati ...
... slightly acidic nature of the GO carbocatalyst, and no changes in the acidity after the reaction.48 (5) EDXS analysis (energydispersive X-ray spectroscopy) of the GO material before the reaction showed C/O atomic ratio of 1.95, which increased to C/O atomic ratio of 3.46 after the reaction, indicati ...
Recent advances in homogeneous nickel catalysis
... have been disclosed. Benzylic cross-coupling Another mode of bond activation that has come to prominence, at least in part thanks to nickel catalysis, is the activation of benzylic C–O bonds37. Benzylic ethers, esters, carbonates, carbamates and, in some instances, even free alcohols (via the corre ...
... have been disclosed. Benzylic cross-coupling Another mode of bond activation that has come to prominence, at least in part thanks to nickel catalysis, is the activation of benzylic C–O bonds37. Benzylic ethers, esters, carbonates, carbamates and, in some instances, even free alcohols (via the corre ...
An efficient acetylation of dextran using in situ activated acetic
... the DS can be controlled. This observation is obvious from the results given in Table I. The products were obtained with excellent yields. The results significantly indicated that this method is highly efficient for the synthesis of dextran acetates as samples 4–6 were obtained with almost complete ...
... the DS can be controlled. This observation is obvious from the results given in Table I. The products were obtained with excellent yields. The results significantly indicated that this method is highly efficient for the synthesis of dextran acetates as samples 4–6 were obtained with almost complete ...
Boron and Metal Catalyzed CC and CH Bond Formation
... dialkynylation of aryl aldehydes using dialkynylboron chloride. Numerous applications of these novel reactions have been developed. These include alternate routes to diphenylmethanes and 1,4-diynes from easily prepared dialkynylboron chlorides. In addition, E and Z alkenyl halides can now be prepare ...
... dialkynylation of aryl aldehydes using dialkynylboron chloride. Numerous applications of these novel reactions have been developed. These include alternate routes to diphenylmethanes and 1,4-diynes from easily prepared dialkynylboron chlorides. In addition, E and Z alkenyl halides can now be prepare ...
Synthesis of Nitrogen-, Oxygen- and Sulphur
... 41.3, 28.5, 13.2. IR (CH2Cl2) νmax 2975, 2932, 1694, 1455, 1414, 1174 cm-1. HRMS (FAB+) m/z calcd for C30H51N3O6. H2O [M+H2O]+ 567.3884. Found: 567.4115. 1,3,5-Tris [(N-tert-butoxycarbonyl-N-isopropyl) aminomethyl]benzene (6d) The general procedure was followed using 1.11 g (7.0 mmol) of 5d, 0.27 g ...
... 41.3, 28.5, 13.2. IR (CH2Cl2) νmax 2975, 2932, 1694, 1455, 1414, 1174 cm-1. HRMS (FAB+) m/z calcd for C30H51N3O6. H2O [M+H2O]+ 567.3884. Found: 567.4115. 1,3,5-Tris [(N-tert-butoxycarbonyl-N-isopropyl) aminomethyl]benzene (6d) The general procedure was followed using 1.11 g (7.0 mmol) of 5d, 0.27 g ...
Chemistry 360 - Athabasca University
... your Lab Write-up. When appropriate, write out any chemical reactions. 3. Introduction Briefly state how the objectives of the experiment will be achieved and provide the relevant background information. 4. Procedure Refer to the lab manual and only note any modifications or changes. Fill out the Ta ...
... your Lab Write-up. When appropriate, write out any chemical reactions. 3. Introduction Briefly state how the objectives of the experiment will be achieved and provide the relevant background information. 4. Procedure Refer to the lab manual and only note any modifications or changes. Fill out the Ta ...
Reactions You Should Know When You Begin Organic II
... Addition of asymmetrical agents follows Markovnikov's Rule except for addition of HBr in the presence of peroxides which adds anti-Markovnikov (only works with HBr). ...
... Addition of asymmetrical agents follows Markovnikov's Rule except for addition of HBr in the presence of peroxides which adds anti-Markovnikov (only works with HBr). ...
Efficient and Convenient Procedure for Protection of Hydroxyl
... processes whereby the protecting groups may be obtained under milder conditions. Results and Discussion Room temperature ionic liquids (RTILs) could be suitable and environmentally safer replacements for the volatile, toxic and flammable organic solvents currently used in synthetic and catalytic rea ...
... processes whereby the protecting groups may be obtained under milder conditions. Results and Discussion Room temperature ionic liquids (RTILs) could be suitable and environmentally safer replacements for the volatile, toxic and flammable organic solvents currently used in synthetic and catalytic rea ...
A Simple and Advantageous Protocol for the Oxidation of Alcohols
... between solvents are their stability to IBX and the slight solubility (or lack thereof) of the IBX-derived byproducts. We regard EtOAc and DCE as the solvents of choice because they are inert and all byproducts are insoluble at room temperature, such that no purification is required beyond simple fi ...
... between solvents are their stability to IBX and the slight solubility (or lack thereof) of the IBX-derived byproducts. We regard EtOAc and DCE as the solvents of choice because they are inert and all byproducts are insoluble at room temperature, such that no purification is required beyond simple fi ...
dr.ebtehal Lec3
... Oxidation is the beginning of the deterioration process. Think of how a slice of apple turns brown when exposed to air. Oxidation leads to the formation of free radicals which are unstable molecules in the body that have one unpaired electron. They can cause oxidation and damage to the cells. This ...
... Oxidation is the beginning of the deterioration process. Think of how a slice of apple turns brown when exposed to air. Oxidation leads to the formation of free radicals which are unstable molecules in the body that have one unpaired electron. They can cause oxidation and damage to the cells. This ...
lec-3- 211( Elim+ Re..
... Oxidation is the beginning of the deterioration process. Think of how a slice of apple turns brown when exposed to air. Oxidation leads to the formation of free radicals which are unstable molecules in the body that have one unpaired electron. They can cause oxidation and damage to the cells. This ...
... Oxidation is the beginning of the deterioration process. Think of how a slice of apple turns brown when exposed to air. Oxidation leads to the formation of free radicals which are unstable molecules in the body that have one unpaired electron. They can cause oxidation and damage to the cells. This ...
R - Evans - Harvard University
... if effective electrophilic aminating agents could be developed. The simple strategy that was envisioned (Scheme 11) held the potential for a useful collection of desirable features, making it complementary to existing methodologies. First, the required starting materials would be the corresponding c ...
... if effective electrophilic aminating agents could be developed. The simple strategy that was envisioned (Scheme 11) held the potential for a useful collection of desirable features, making it complementary to existing methodologies. First, the required starting materials would be the corresponding c ...
Mock Exam One
... b.) In general, aldehydes are more reactive than ketones. c.) Nucleophilic addition to carbonyl groups can be catalyzed by acid or base. d.) Addition of a nucleophile to a carbonyl group changes the hybridization of the carbonyl carbon from sp3 to sp2. ...
... b.) In general, aldehydes are more reactive than ketones. c.) Nucleophilic addition to carbonyl groups can be catalyzed by acid or base. d.) Addition of a nucleophile to a carbonyl group changes the hybridization of the carbonyl carbon from sp3 to sp2. ...
hydrogen peroxide disproportionation and organic
... The reactivity of olefins with hydroxyl radicals.11 .....................................................7 ...
... The reactivity of olefins with hydroxyl radicals.11 .....................................................7 ...
Atmospheric Formation_TELTEK
... 2.2 (CH3)2NH Atkinson et al.19 studied the kinetics of the OH radical reaction with (CH3)2NH over the temperature range 299 – 426 K and reported a negative Arrhenius activation energy, kOH(T) = 2.89×10-11 × exp{(245 ± 150)K/T} and kOH = (6.54 ± 0.66) × 10-11 cm3 molecule-1 s-1 at 298 K. Carl and Cro ...
... 2.2 (CH3)2NH Atkinson et al.19 studied the kinetics of the OH radical reaction with (CH3)2NH over the temperature range 299 – 426 K and reported a negative Arrhenius activation energy, kOH(T) = 2.89×10-11 × exp{(245 ± 150)K/T} and kOH = (6.54 ± 0.66) × 10-11 cm3 molecule-1 s-1 at 298 K. Carl and Cro ...
Improved Synthesis, Separation, Transition Metal Coordination and
... The 6-10.5 ppm region of the 1H NMR spectra: sample from reaction with 1-hexene, meso-(et,ph-P4) in acetone-d6/ D2O under N2, 24 hours (blue spectrum), same as above recorded 1.5 hours after exposure to O2(red spectrum).......................................................... 68 ...
... The 6-10.5 ppm region of the 1H NMR spectra: sample from reaction with 1-hexene, meso-(et,ph-P4) in acetone-d6/ D2O under N2, 24 hours (blue spectrum), same as above recorded 1.5 hours after exposure to O2(red spectrum).......................................................... 68 ...
Hydrogenation, Transfer Hydrogenat- ion and Hydrogen Transfer Reactions
... Rhodium, ruthenium and iridium catalysts have achieved great success in stereoselective homogeneous hydrogenation.10 The study of homogeneous iridium catalysis was initiated in the 1960s with IrCl(CO)(PPh3)2 (Vaska’s complex) by Lauri Vaska.11 Under hydrogen pressure, it formed the dihydride comple ...
... Rhodium, ruthenium and iridium catalysts have achieved great success in stereoselective homogeneous hydrogenation.10 The study of homogeneous iridium catalysis was initiated in the 1960s with IrCl(CO)(PPh3)2 (Vaska’s complex) by Lauri Vaska.11 Under hydrogen pressure, it formed the dihydride comple ...
boehm_rl
... ethyl methylchloroacetate, ethyl phenylchloroacetate, and ethyl diphenylchloroacetate from the corresponding alcohols. Bissinger and Kung (32) studied the effects of varying experimental conditions upon the reactions of propyl alcohols and thionyl chloride . In order to prepare unstable propyl sulfi ...
... ethyl methylchloroacetate, ethyl phenylchloroacetate, and ethyl diphenylchloroacetate from the corresponding alcohols. Bissinger and Kung (32) studied the effects of varying experimental conditions upon the reactions of propyl alcohols and thionyl chloride . In order to prepare unstable propyl sulfi ...
Scope and Limitations - Organic Reactions Wiki
... Osmium tetroxide has since established itself as the reagent of choice for the syndihydroxylation of olefins, primarily because of its inertness toward other functional groups and lack of over-oxidation products.4 Researchers from the UpJohn company reported a convenient and reliable procedure for ...
... Osmium tetroxide has since established itself as the reagent of choice for the syndihydroxylation of olefins, primarily because of its inertness toward other functional groups and lack of over-oxidation products.4 Researchers from the UpJohn company reported a convenient and reliable procedure for ...
Hofmann–Löffler reaction
The Hofmann–Löffler reaction (also referred to as Hofmann–Löffler–Freytag reaction, Löffler–Freytag reaction, Löffler–Hofmann reaction, as well as Löffler's method) is an organic reaction in which a cyclic amine 2 (pyrrolidine or, in some cases, piperidine) is generated by thermal or photochemical decomposition of N-halogenated amine 1 in the presence of a strong acid (concentrated sulfuric acid or concentrated CF3CO2H). The Hofmann–Löffler–Freytag reaction proceeds via an intramolecular hydrogen atom transfer to a nitrogen-centered radical and is an example of a remote intramolecular free radical C–H functionalization.