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Slide 1
Slide 1

... burden of 1.7 billion cases worldwide [One-third of worlds population is now estimated to be infected with this potentially devastating infection] • In 1993, the World Health Organization declared tuberculosis as public health emergency, as 3 million patients were expected to die annually due to com ...
Migration and HIV
Migration and HIV

... ‘those entering the UK through the immigration system would require [sic] to have such tests at the point of application and to pay for them, whilst those seeking asylum would be detained until it was clear the criteria had been met’ ...
Transmissiion and pathogenesis of Tuberculosis
Transmissiion and pathogenesis of Tuberculosis

... • 7-21 days after initial infection – mycobact tuberculosis multiplies within macrophages until the macrophages burst. • Then: – T cells become activated and liberate cytokines, including gamma interferon – the individual becomes tuberculin-positive – activated macrophages may release lytic enzymes ...
Group A Streptococcus: Commonly Asked Questions
Group A Streptococcus: Commonly Asked Questions

... highest when a person is ill, such as when people have "strep throat" or an infected wound. People who carry the bacteria but have no symptoms are much less able to spread the bacteria. Treatment of an infected person with an appropriate antibiotic for 24 hours or longer removes their ability to spr ...
Chapter 18 - Environmental Hazards and Human
Chapter 18 - Environmental Hazards and Human

... Worldwide, infectious disease is the number one killer. (This includes TB, HIV, malaria, flu, measles, cholera, and yellow fever.) ...
Left tender Cervical Mass
Left tender Cervical Mass

... – The lymph node number, location, size, shape, consistency, tenderness, mobility, and color should be recorded. • "Reactive" lymph nodes are usually discrete, mobile, feel rubbery, and are minimally tender. • Infected lymph nodes are usually isolated, asymmetric, tender, warm, and erythematous; the ...
Invasive Group A Streptococcal (iGAS) Disease
Invasive Group A Streptococcal (iGAS) Disease

... Group A Strep is spread through direct contact with the nose or mouth secretions of an infected person, for example, through open mouth kissing, mouth-to-mouth resuscitation or through direct contact with infected sores on the skin. ...
Occupational Infection
Occupational Infection

3201-notes on STIS File
3201-notes on STIS File

... -Stage A (~1 year):  No symptoms, but can still infect other people -Stage B (~6-8 years):  Lymph nodes swell  Weight loss  Night sweats  Fatigue  Fever  Diarrhea  Recurring infections (ex: herpes and thrush) -Stage C (Full blown AIDS)  Patient begins suffering from nervous disorders  Oppo ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

... foreign-born individuals will be of major importance in meeting the goals for eliminating tuberculosis in U.S.[9].Tuberculosis remains tremendous problem outside United States. It is estimated that one-third of the world’s population, almost 2 billion persons, is infected with M.tuberculosis.For thi ...
Infectious Mononucleosis Fever Sore Throat
Infectious Mononucleosis Fever Sore Throat

... in signaling lymphocytic activation moleculeassociated protein  Characterized by  Nodular ...
Streptococcus equi
Streptococcus equi

... • All infected horses and their in-contacts should remain in strict isolation. • Horses should not enter an affected premises unless can be isolated ...
List 5 ways can students minimize the spread of pathogens at school?
List 5 ways can students minimize the spread of pathogens at school?

... nodes, headache, and fever. People can become infected with the bacteria that cause Lyme disease when they are bitten by an infected tick. Symptoms include a rash at the site of the bite. Bacterial meningitis is an infection of the fluid surrounding the spinal cord and the brain. Symptoms include he ...
Epidemiology of Emerging Infectious Diseases: Global Threats to
Epidemiology of Emerging Infectious Diseases: Global Threats to

... Estimated 15 million Americans with latent infections  Minorities affected disproportionately [as is the case with many other infectious diseases] – 54% active M. Tuberculosis cases (1995) reported among African American and Hispanic populations – An additional 17.5% among Asians  In some U.S. sec ...
Sexually Transmitted Infections
Sexually Transmitted Infections

... vaccine, so women who receive it still need Pap tests.) It is estimated that as many as one in five Americans have genital herpes, a lifelong (but manageable) infection, yet up to 90 percent of those with herpes are unaware they have it. With more than 50 million adults in the US with genital herpes ...
Heart disease: the greatest `risk`
Heart disease: the greatest `risk`

... approximately 25 million US patients that have none of the risk factors associated with heart disease, yet are at risk for a heart attack. However CRP and elevated sedimentation rate have long been excellent markers of active tuberculosis [22], CRP being present at all times when erythrocyte sedimen ...
Slide 1
Slide 1

... Creation of Redundant entries – Records with repetition of Rv ...
Introduction to infectious diseases
Introduction to infectious diseases

... Incubation period: time from infection to appearance of symptoms Latent period: time from infection to beginning of transmission - called pre-patent period for macroparasites Infectious period: time during which individual can transmit disease - may not be the same as symptomatic period!! Generation ...
Chapter 19 - eacfaculty.org
Chapter 19 - eacfaculty.org

... sputum, fever, anorexia, weight loss, fatigue ...
OXGENATION DEFICITS
OXGENATION DEFICITS

... * A positive test is determined by the size of the area of induration (hardened & raised area) ...
EHS EXERCISE 1 - Global Tuberculosis Institute
EHS EXERCISE 1 - Global Tuberculosis Institute

... Transmission of Mycobacterium tuberculosis in Health-Care Setting, 2005” from Morbidity and Mortality Weekly Report December 30, 2005 / 54(RR17);1-141. Use the information provided in this excerpt to answer the remaining questions in this exercise. Fundamentals of TB Infection Control2 One of the mo ...
Lecture 8
Lecture 8

... - Survive after ingestion by macrophages. ...
Mathematical Analysis Of The Endemic Equilibrium Of
Mathematical Analysis Of The Endemic Equilibrium Of

Management of Hospitalized Patients with Suspected Pulmonary
Management of Hospitalized Patients with Suspected Pulmonary

... development of cellular immunity and tissue hypersensitivity c. TST is recommended yearly for HCW and other high risk groups 1. If TST was done more than 1 year ago in newly hired HCWs, boosting with a second TST is recommended to exclude remote infection in which cellular immunity hypersensitivity ...
Emerging Infections: Perfect Storm of Vulnerability and
Emerging Infections: Perfect Storm of Vulnerability and

... Stop TB Partnership targets ...
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Tuberculosis



Tuberculosis, MTB, or TB (short for tubercle bacillus), in the past also called phthisis, phthisis pulmonalis, or consumption, is a widespread, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis typically attacks the lungs, but can also affect other parts of the body. It is spread through the air when people who have an active TB infection cough, sneeze, or otherwise transmit respiratory fluids through the air. Most infections do not have symptoms, known as latent tuberculosis. About one in ten latent infections eventually progresses to active disease which, if left untreated, kills more than 50% of those so infected.The classic symptoms of active TB infection are a chronic cough with blood-tinged sputum, fever, night sweats, and weight loss (the last of these giving rise to the formerly common term for the disease, ""consumption""). Infection of other organs causes a wide range of symptoms. Diagnosis of active TB relies on radiology (commonly chest X-rays), as well as microscopic examination and microbiological culture of body fluids. Diagnosis of latent TB relies on the tuberculin skin test (TST) and/or blood tests. Treatment is difficult and requires administration of multiple antibiotics over a long period of time. Household, workplace and social contacts are also screened and treated if necessary. Antibiotic resistance is a growing problem in multiple drug-resistant tuberculosis (MDR-TB) infections. Prevention relies on early detection and treatment of cases and on screening programs and vaccination with the bacillus Calmette-Guérin vaccine.One-third of the world's population is thought to have been infected with M. tuberculosis, and new infections occur in about 1% of the population each year. In 2007, an estimated 13.7 million chronic cases were active globally, while in 2013, an estimated 9 million new cases occurred. In 2013 there were between 1.3 and 1.5 million associated deaths, most of which occurred in developing countries. The total number of tuberculosis cases has been decreasing since 2006, and new cases have decreased since 2002. The rate of tuberculosis in different areas varies across the globe; about 80% of the population in many Asian and African countries tests positive in tuberculin tests, while only 5–10% of the United States population tests positive. More people in the developing world contract tuberculosis because of a poor immune system, largely due to high rates of HIV infection and the corresponding development of AIDS.
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