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European Respiratory Society Annual Congress 2013
European Respiratory Society Annual Congress 2013

... Body: Background Current international guidelines recommend patients with smear positive pulmonary tuberculosis (TB) have respiratory isolation for 2 weeks after starting treatment. Identifying patients who are more likely to need prolonged periods of respiratory isolation can be used to reduce infe ...
TB and the Mexican Border: BCG, Practices & Complications
TB and the Mexican Border: BCG, Practices & Complications

... developed to address this deficiency, but so far there has been no unequivocal demonstration of the effectiveness of this strategy in reducing transmission of M. tuberculosis. ...
Chapter 19
Chapter 19

... result based on size of wheal and specific population factors ...
Definition Chal•lenge Noun • a call to take part in a contest or
Definition Chal•lenge Noun • a call to take part in a contest or

... Why are we so far from the finish line? “The biggest gap is in the limited messaging about  the failure of the national TB elimination plan. I am  sure that few officials are aware that there is  actually a national plan to eliminate TB in this  country. In fact, the public thinks it has already  ha ...
Thursday, December 7 - American Statistical Association
Thursday, December 7 - American Statistical Association

... 1900, and it has consistently ranked among the 10 leading causes of death throughout the entire century. The other, tuberculosis, was the leading cause of death in 1900, but it has long since fallen from among the 10 leading causes and is now largely controlled. Influenza is a constant and continual ...
EPI Fact Sheet 1: Primary, Secondary, and Tertiary Prevention Fact
EPI Fact Sheet 1: Primary, Secondary, and Tertiary Prevention Fact

... Directly observed therapy (DOT) is suggested for patients with LTBI at high risk of not adhering to the prescribed therapy, and mandatory for those on twice weekly regimens. For DOT, a health care worker or other trained person who is not a family member watches as the patient swallows antituberculo ...
Infection Control in the School Setting
Infection Control in the School Setting

... Is a very durable virus and can survive outside of the body for at least 7 days.  It is very important to clean up any blood or body fluid spills. (Can use a 1:10 bleach solution – which is 1 part household bleach to 9 parts water.) ...
A Deadly Duo: Diabetes and Tuberculosis
A Deadly Duo: Diabetes and Tuberculosis

Official American Thoracic Society/Infectious Diseases
Official American Thoracic Society/Infectious Diseases

... Background.  Individuals infected with Mycobacterium tuberculosis (Mtb) may develop symptoms and signs of disease (tuberculosis disease) or may have no clinical evidence of disease (latent tuberculosis infection [LTBI]). Tuberculosis disease is a leading cause of infectious disease morbidity and mor ...
Childhood contact screening and management [Official Statement
Childhood contact screening and management [Official Statement

... consider IPT for all ages, including those aged 5 years. As with other contacts, active disease should be ruled out, and only HIV-infected children who are healthy should be offered IPT. HIV-infected children who have symptoms should be carefully evaluated for TB, and if found to have TB disease, t ...
Republic of Latvia
Republic of Latvia

... departments of medical treatment institutions; maternity hospitals (departments) and newborn departments if the group illness of patients (two cases and more) caused by the relevant strain of pathogenic staphylococcus acquired in the medical treatment institution has been registered); 4.8. carrying ...
MICROBIOLOGY/INFECTIOUS DISEASES
MICROBIOLOGY/INFECTIOUS DISEASES

... dormant for years, perhaps by being sequestered from CD4(+) T-cells which have been sensitized to MTB b. Can persist at disseminated foci 2° dissemination of organism throughout entire body during initial phases of infection —Certain sites favorable for persistence of organism—lung apices, lymph nod ...
Mycobacterium Tuberculosis and Hepatitis Co
Mycobacterium Tuberculosis and Hepatitis Co

Health and pathogens
Health and pathogens

... • More reproduction within RBCs causes these cells to swell and burst (lysis) • The mosquito feeds on the blood of a non-infected human • Anopheles mosquito ingests a blood meal from an infected human ...
microbe detectives through the ages…
microbe detectives through the ages…

... What is a Microorganism? ...
Disease spectrum - Medical Biostatistics
Disease spectrum - Medical Biostatistics

... and health centers find a sudden rise in cases amongst the patients they attend, epidemic can be safely presumed. Calling slight excess as epidemic and getting a premature alarm is not as bad as being caught unawares for high occurrence. Thus, even a suspicion of increased incidence is good for heal ...
Presentation - LSU School of Medicine
Presentation - LSU School of Medicine

... • If AFB positive, NAA negative and Inhibitors detected, NAA test is of no use • If AFB is negative, NAA negative, Inhibitors negative, use clinical judgment as sensitivity of NAA in smear negative , culture positive cases is ...
continued - Human Kinetics
continued - Human Kinetics

... and nasal congestion. • Distinctive symptom is a dry cough, resulting in coughing bouts that can last for several minutes and that end with a whooping sound. • Can be treated with antibiotics. ...
the importance of contact history in childhood tuberculosis
the importance of contact history in childhood tuberculosis

extended-spectrum beta-lactamase producing bacteria
extended-spectrum beta-lactamase producing bacteria

... What are extended-spectrum beta-lactamase (ESBL) producing bacteria?  ESBLs are enzymes produced by bacteria, such as Klebsiella and Escherichia coli  These enzymes make certain antibiotics ineffective  The extended-spectrum (third generation) antibiotics affected can be Cefotaxime, Ceftazidime o ...
Poster
Poster

... fatal if not treated promptly. 3-dehydroquinate dehydratase (DHQase) is an enzyme that catalyzes the third step of the shikimate pathway, which is essential to M. tuberculosis. The shikimate pathway creates a precursor to the aromatic amino acids phenylalanine, tyrosine, and tryptophan. Inhibition o ...
Chapter 17 Human Health and Environmental Risks
Chapter 17 Human Health and Environmental Risks

... What are some risks of chronic disease in developing countries/ low income? ...
How was bovine tuberculosis detected in Kentucky
How was bovine tuberculosis detected in Kentucky

... bacterium Mycobacterium bovis (M. bovis). Bovine TB primarily affects cattle; however, other animals may become infected. M. Bovis causes a disease that can be transmitted between wildlife populations and food animals (e.g., cattle). Disease due to M. bovis in animals typically presents in the lungs ...
Infection Control Policy
Infection Control Policy

... Children who are unwell with an infectious disease should not be at nursery school. Once they are better they are able to return unless they pose a risk of infection to others. They should not return to nursery school until the risk has passed. ...
Tuberculosis
Tuberculosis

... Tuberculosis • Mycobacterium tuberculosis – Fastidious, aerobic, acid-fast bacillus ...
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Tuberculosis



Tuberculosis, MTB, or TB (short for tubercle bacillus), in the past also called phthisis, phthisis pulmonalis, or consumption, is a widespread, infectious disease caused by various strains of mycobacteria, usually Mycobacterium tuberculosis. Tuberculosis typically attacks the lungs, but can also affect other parts of the body. It is spread through the air when people who have an active TB infection cough, sneeze, or otherwise transmit respiratory fluids through the air. Most infections do not have symptoms, known as latent tuberculosis. About one in ten latent infections eventually progresses to active disease which, if left untreated, kills more than 50% of those so infected.The classic symptoms of active TB infection are a chronic cough with blood-tinged sputum, fever, night sweats, and weight loss (the last of these giving rise to the formerly common term for the disease, ""consumption""). Infection of other organs causes a wide range of symptoms. Diagnosis of active TB relies on radiology (commonly chest X-rays), as well as microscopic examination and microbiological culture of body fluids. Diagnosis of latent TB relies on the tuberculin skin test (TST) and/or blood tests. Treatment is difficult and requires administration of multiple antibiotics over a long period of time. Household, workplace and social contacts are also screened and treated if necessary. Antibiotic resistance is a growing problem in multiple drug-resistant tuberculosis (MDR-TB) infections. Prevention relies on early detection and treatment of cases and on screening programs and vaccination with the bacillus Calmette-Guérin vaccine.One-third of the world's population is thought to have been infected with M. tuberculosis, and new infections occur in about 1% of the population each year. In 2007, an estimated 13.7 million chronic cases were active globally, while in 2013, an estimated 9 million new cases occurred. In 2013 there were between 1.3 and 1.5 million associated deaths, most of which occurred in developing countries. The total number of tuberculosis cases has been decreasing since 2006, and new cases have decreased since 2002. The rate of tuberculosis in different areas varies across the globe; about 80% of the population in many Asian and African countries tests positive in tuberculin tests, while only 5–10% of the United States population tests positive. More people in the developing world contract tuberculosis because of a poor immune system, largely due to high rates of HIV infection and the corresponding development of AIDS.
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