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encephalitis_Hogan
encephalitis_Hogan

... • 60,000 estimated human deaths annually worldwide • 1-3 deaths per year in U.S. • Dogs in developing countries • Wild animals in developed countries (skunk, raccoon, fox, bat) • Bites, inhalation, transplant • U.S., major source is bat (often no history of a bite) ...
Novel Inflammatory Markers, Clinical Risk Factors and Virus Type
Novel Inflammatory Markers, Clinical Risk Factors and Virus Type

... isolates are divided into 2 major groups, A and B, due to differences in the amino acid sequence of the attachment G protein. The 2 major groups usually circulate simultaneously, but the proportion of infection caused by group A or B viruses differ from season to season9 with type A seasons generall ...
Sore Throat - Cal Maritime Academy
Sore Throat - Cal Maritime Academy

... Sore throats can be due to infectious mononucleosis (i.e., mono). If your provider suspects this he or she may order a blood test. However, sometimes symptoms may have to be present for a week before the test confirms the infection. Mononucleosis is a viral infection caused by a type of herpes virus ...
FIV Feline Immunodeficiency Virus
FIV Feline Immunodeficiency Virus

... the new born kittens ingest infected milk. ...
159 Feline Infectious Peritonitis: Clinical and Anatomopathological
159 Feline Infectious Peritonitis: Clinical and Anatomopathological

... presence of liver nodules, blood vessels swelling were observed. In some cases, in exploratory laparotomy, tumors on the stomach, pancreas, intestine, mesentery, fibrin, ascites fluid were found. In three cases, necropsy was performed, but not immediately after the death of animals, for objective re ...
SART logo
SART logo

... species of both domestic and wild animals can be susceptible to FMD ...
Picornaviruses
Picornaviruses

... for cellular receptors is the major determinant of the target tissue tropism and disease VP1 and “canyon” 80% of rhinoviruses and several serotypes of of coxsackieviruses recognize ICAM-1 ...
Bloodborne Pathogens - Brownfields Toolbox
Bloodborne Pathogens - Brownfields Toolbox

... 3. True. Infected bodily fluids need to directly contact mucous membranes or nonintact skin. 4. True. Although many bodily fluids may be infectious, they must contain blood to carry bloodborne ...
Structures of immature flavivirus particles
Structures of immature flavivirus particles

... Three E monomers per icosahedral asymmetric unit could easily be positioned into the cryoEM density of the immature particle reconstruction (Table I). The organization of the three monomers does not conform to T = 3 quasi-symmetry (Caspar and Klug, 1962) (Figure 3C and D), as is also the case for th ...
What is Dengue?1
What is Dengue?1

... have been made for both African and Indochinese origins and circumstantial evidence for tropical Asian origin is strong. Dengue-like diseases were reported from China as early as 265-420 AD, but the first documented case of the disease was reported by Benjamin Rush from Philadelphia in 1780. Almost ...
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Detection of yellow fever virus: a comparison of

... Yellow fever virus quantitation is performed routinely by cultivation of virus containing samples using susceptible cells. Counting of the resulting plaques provides a marker for the number of infectious particles present in the sample. This assay usually takes up to 5 days before results are obtain ...
Virus and Viroid Plant Pathogens
Virus and Viroid Plant Pathogens

... Healthy cells Proteinaceous crystals increase in number & aggregate with some Potyvirus infections ...
Novel antibody binding determinants on the capsid surface of
Novel antibody binding determinants on the capsid surface of

... none of the mAbs bound to the mutant viruses (Fig. 2a), confirming the abrogation of mAb binding in the mutant viruses. In the ELISA, pooled and individual guinea pig antisera were able to react to varying degrees with the recombinant viruses as well as all the rO1K-wt virus (Fig. 2b), suggesting th ...
Feline Immunodeficiency Virus (FIV) and Feline
Feline Immunodeficiency Virus (FIV) and Feline

... Is there any treatment for FeLV? Unfortunately, there is currently no reliable treatment for FeLV so vets will treat each FeLV-positive cat individually, depending on the signs they develop. Sadly the outlook is likely to be poor. Keeping infected cats indoors and ensuring they are fully vaccinated ...
Feline Immunodeficiency
Feline Immunodeficiency

... is a reliable diagnostic method but is laborious and not used routinely. The preferred initial tests are ELISA or immunochromatographic test, which detect antibodies recognizing viral structural proteins (such as the capsid protein p24 and a gp41 peptide) and offer the advantage of speed and conveni ...
Real time RT-PCR for SFTS virus
Real time RT-PCR for SFTS virus

... detected from the only one serum specimens among 180 specimens of dengue negative (Tables 3 and 4, Figures 2 and 3)  Our results suggest that co-infection of dengue virus with Plasmodium spp. or SFTSV is not generally occurred at least in Korea travelers (Table 3 and 4).  Co-infection of dengue wi ...
Causes of Gizzard Erosion and Proventriculitis in
Causes of Gizzard Erosion and Proventriculitis in

... causing superficial gizzard erosion. The correlation between the presence of biogenic amines and poor results in broilers has been observed in the Southeast of the U.S., including proventricular enlargement and hypertrophy of the papillary glands. In spite of these reports, most scientific papers p ...
Feline Infectious Peritonitis (FIP)
Feline Infectious Peritonitis (FIP)

... At this time the diagnosis of FIP is clinical. This means that there is no positive or negative test; the doctor must look at the sum of several findings. These are some of the findings that are coupled with the physical examination and history findings to come up with a diagnosis of FIP. We have a ...
objective - Mungo Foundation
objective - Mungo Foundation

... then contact, National Health Service direct (0845 4647) and your General Practitioner, who will advise you what to do, this process will be in operation at the outset of the pandemic. You should not return to work unless advised to do so and must also keep your manager informed throughout this proc ...
The Highly Pathogenic Avian Influenza H5N1 – Initial Molecular
The Highly Pathogenic Avian Influenza H5N1 – Initial Molecular

... This virus infected eighteen people, causing the death of six. Analysis of the viral gene indicated that all viruses isolated from patients were the avian influenza virus (H5N1).(1-4) Subsequently, the spread of the virus was temporarily halted but was again transmitted to humans in 2003, spreading ...
Executive Summary Kansas State University Testing
Executive Summary Kansas State University Testing

... pathogenic and infectious isolate is heightened during ongoing outbreaks, which could result in a devastating human-to-human transmissibility. Influenza virus is typically spread via aerosols, large droplets, or contact with infectious secretions or fomites (4). Rapid containment of an outbreak is i ...
CHAPTER 15 Causes and spread of infection
CHAPTER 15 Causes and spread of infection

... The difference between infectious and non-infectious disease is that infectious disease can be spread from person to person. Infection can pass from person to person by cross-contamination (cross-infection, indirect contamination) or by direct contact (direct contamination). Cross-contamination is w ...
Outbreak of West Nile virus infection among
Outbreak of West Nile virus infection among

... indicated that WNV was circulating in nearby countries, suggesting that human cases of WNV infection could be expected in Serbia as well. In 2011, Lupulovic et al. reported the first serological evidence of WNV infection in Serbia as a zoonosis: they showed that 42 (12%) of 349 horses analysed had W ...
Final Report: SIBURIAN - International Society for Infectious Diseases
Final Report: SIBURIAN - International Society for Infectious Diseases

... Padang, specifi cally in Minangkabau ethnic group. Although another study reported that HBV genotype C was also prevalent in the eastern part of Indonesia (Moluccas and Papua), the main subgenotypes in this area were C5 and C6 [4, 10], different with genotype C found in Minangkabau ethnic. In oth ...
CDC and Partner Activities to Explore Community Mitigation
CDC and Partner Activities to Explore Community Mitigation

... of persons ill with infectious disease Quarantine: Restriction of persons who are not ill but presumed exposed, in the home or a designated facility Social Distancing: Measures to increase the space between people and decrease the frequency of contact among people ...
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Ebola virus disease



Ebola virus disease (EVD; also Ebola hemorrhagic fever, or EHF), or simply Ebola, is a disease of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected, with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals. This may also occur through contact with an item recently contaminated with bodily fluids. Spread of the disease through the air between primates, including humans, has not been documented in either laboratory or natural conditions. Semen or breast milk of a person after recovery from EVD may still carry the virus for several weeks to months. Fruit bats are believed to be the normal carrier in nature, able to spread the virus without being affected by it. Other diseases such as malaria, cholera, typhoid fever, meningitis and other viral hemorrhagic fevers may resemble EVD. Blood samples are tested for viral RNA, viral antibodies or for the virus itself to confirm the diagnosis.Control of outbreaks requires coordinated medical services, alongside a certain level of community engagement. The medical services include rapid detection of cases of disease, contact tracing of those who have come into contact with infected individuals, quick access to laboratory services, proper healthcare for those who are infected, and proper disposal of the dead through cremation or burial. Samples of body fluids and tissues from people with the disease should be handled with special caution. Prevention includes limiting the spread of disease from infected animals to humans. This may be done by handling potentially infected bush meat only while wearing protective clothing and by thoroughly cooking it before eating it. It also includes wearing proper protective clothing and washing hands when around a person with the disease. No specific treatment or vaccine for the virus is available, although a number of potential treatments are being studied. Supportive efforts, however, improve outcomes. This includes either oral rehydration therapy (drinking slightly sweetened and salty water) or giving intravenous fluids as well as treating symptoms.The disease was first identified in 1976 in two simultaneous outbreaks, one in Nzara, and the other in Yambuku, a village near the Ebola River from which the disease takes its name. EVD outbreaks occur intermittently in tropical regions of sub-Saharan Africa. Between 1976 and 2013, the World Health Organization reports a total of 24 outbreaks involving 1,716 cases. The largest outbreak is the ongoing epidemic in West Africa, still affecting Guinea and Sierra Leone. {{#section:Ebola virus epidemic in West Africa|casesasof}}, this outbreak has {{#section:Ebola virus epidemic in West Africa|cases}} reported cases resulting in {{#section:Ebola virus epidemic in West Africa|deaths}} deaths.{{#section:Ebola virus epidemic in West Africa|caserefs}}
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