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Chapter 10
Chapter 10

... encephalitis, and Colorado tick fever are common to the United States. These are all RNA viruses. Colorado tick fever is the most common tickborne viral fever in the United States. Humans do not serve as reservoirs; these viruses cycle between wild animals (primarily birds) and mosquitoes; humans an ...
Bacteria and Viruses
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... are “infectious proteins”  They are normal body proteins that get converted into an alternate configuration by contact with other prion proteins  They have no DNA or RNA The main protein involved in human and mammalian prion diseases is called “PrP” copyright cmassengale ...
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... Mareks disease herpesvirus, which causes lym- antigen over a period of several weeks. We phomas in chickens, is highly cell-associated. purposely included tissues from which virus Keratinized cells surrounding the feather shafts in could gain access to the environment, since the skin were found to b ...
12 Chapter 38 Rodent - University of Northern Colorado
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... Lassa, Nigeria Reservoir is Mastomys spp. rodents Epidemiology About 200,000 cases per year About 5,000 fatalities per year Some evidence of person-to-person transmission Lassa Fever (hemorrhagic fever) Body aches, chest pain, vomiting, cough, fatigue Hypotension, pleural effusions, proteinuria, hea ...
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... A deadly and highly contagious disease can reach epidemic proportions more quickly than it can be combatted if proper steps are not taken. Derek Gatherer of the Journal of General Virology warns, “[t]he case fatality rate in [Ebola virus disease] is so high, approaching 90% in some outbreaks… that m ...
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... • Infectious virus present at all times • Disease may be present or absent • Best example is Hepatitis Type B virus – Carriers produce virus detected in blood, saliva, and semen – Unique replication of dsDNA ...
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... programme  to  support  the  development,  manufacturing  and  deployment  of  the  vaccine   regimen.  In  September  2015,  Crucell  Holland  B.V.,  one  of  the  Janssen  Pharmaceutical   Companies,  was  awarded  $28.5  million  from  Th ...
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Modeling the SARS Outbreak in Toronto, Canada

... Spread of SARS • Travels in water droplets spread by coughing/sneezing • Droplets can be infectious for up to 6 hours • Household disinfectants like bleach are effective at killing the virus ...
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Ebola virus disease



Ebola virus disease (EVD; also Ebola hemorrhagic fever, or EHF), or simply Ebola, is a disease of humans and other primates caused by ebolaviruses. Signs and symptoms typically start between two days and three weeks after contracting the virus with a fever, sore throat, muscular pain, and headaches. Then, vomiting, diarrhea and rash usually follow, along with decreased function of the liver and kidneys. At this time some people begin to bleed both internally and externally. The disease has a high risk of death, killing between 25 and 90 percent of those infected, with an average of about 50 percent. This is often due to low blood pressure from fluid loss, and typically follows six to sixteen days after symptoms appear.The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals. This may also occur through contact with an item recently contaminated with bodily fluids. Spread of the disease through the air between primates, including humans, has not been documented in either laboratory or natural conditions. Semen or breast milk of a person after recovery from EVD may still carry the virus for several weeks to months. Fruit bats are believed to be the normal carrier in nature, able to spread the virus without being affected by it. Other diseases such as malaria, cholera, typhoid fever, meningitis and other viral hemorrhagic fevers may resemble EVD. Blood samples are tested for viral RNA, viral antibodies or for the virus itself to confirm the diagnosis.Control of outbreaks requires coordinated medical services, alongside a certain level of community engagement. The medical services include rapid detection of cases of disease, contact tracing of those who have come into contact with infected individuals, quick access to laboratory services, proper healthcare for those who are infected, and proper disposal of the dead through cremation or burial. Samples of body fluids and tissues from people with the disease should be handled with special caution. Prevention includes limiting the spread of disease from infected animals to humans. This may be done by handling potentially infected bush meat only while wearing protective clothing and by thoroughly cooking it before eating it. It also includes wearing proper protective clothing and washing hands when around a person with the disease. No specific treatment or vaccine for the virus is available, although a number of potential treatments are being studied. Supportive efforts, however, improve outcomes. This includes either oral rehydration therapy (drinking slightly sweetened and salty water) or giving intravenous fluids as well as treating symptoms.The disease was first identified in 1976 in two simultaneous outbreaks, one in Nzara, and the other in Yambuku, a village near the Ebola River from which the disease takes its name. EVD outbreaks occur intermittently in tropical regions of sub-Saharan Africa. Between 1976 and 2013, the World Health Organization reports a total of 24 outbreaks involving 1,716 cases. The largest outbreak is the ongoing epidemic in West Africa, still affecting Guinea and Sierra Leone. {{#section:Ebola virus epidemic in West Africa|casesasof}}, this outbreak has {{#section:Ebola virus epidemic in West Africa|cases}} reported cases resulting in {{#section:Ebola virus epidemic in West Africa|deaths}} deaths.{{#section:Ebola virus epidemic in West Africa|caserefs}}
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