Tuberculosis Chemotherapy
... • 1st line essential drugs– most effective & basic components of anti tubercular treatment. • 1st linesupplemental drugs– are quite effective & posseses an acceptable limit of toxicity. These are kept as reserved drugs & used in special settings. • 2nd line drugs—these drugs are used if there is re ...
... • 1st line essential drugs– most effective & basic components of anti tubercular treatment. • 1st linesupplemental drugs– are quite effective & posseses an acceptable limit of toxicity. These are kept as reserved drugs & used in special settings. • 2nd line drugs—these drugs are used if there is re ...
Regulation of Over-The-Counter Drugs - Power
... essence these other products are subject to the same restrictions that the FDA may place on traditional tobacco cigarettes. In contrast, conventional products specifically intended for smoking cessation are generally subject to the FDA’s usual drug approval process for therapeutic agents. In enactin ...
... essence these other products are subject to the same restrictions that the FDA may place on traditional tobacco cigarettes. In contrast, conventional products specifically intended for smoking cessation are generally subject to the FDA’s usual drug approval process for therapeutic agents. In enactin ...
ARRx_Notification_20150209
... these point-of-sale (POS) prior authorization criteria edits. If the prescriber believes that a non-preferred product is medically necessary or the patient does not meet applicable point-of-sale edits, the prescriber must contact the EBRx PDL Prior Authorization (PA) Call Center at (Local) 501-526-4 ...
... these point-of-sale (POS) prior authorization criteria edits. If the prescriber believes that a non-preferred product is medically necessary or the patient does not meet applicable point-of-sale edits, the prescriber must contact the EBRx PDL Prior Authorization (PA) Call Center at (Local) 501-526-4 ...
Chapter 2-3 PPT
... b. they can twist and fold into many different and complex structures. c. they contain nitrogen as well as carbon, hydrogen, and oxygen. d. their R groups can be either acidic or basic. ...
... b. they can twist and fold into many different and complex structures. c. they contain nitrogen as well as carbon, hydrogen, and oxygen. d. their R groups can be either acidic or basic. ...
2013_Adverse effects..
... pregnant women have demonstrated a risk to the fetus. • However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective. • Phenytoin, cancer ...
... pregnant women have demonstrated a risk to the fetus. • However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective. • Phenytoin, cancer ...
state burn reversible physical melt irreversible different particles
... If you heat ice it will ____ into water. This is a _________ change. Physical changes often involve a change of _____. They are __________ which means they can be easily undone. In a physical change, no new material is formed. If you heat bread it will _____ and become toast. Burning is a ________ c ...
... If you heat ice it will ____ into water. This is a _________ change. Physical changes often involve a change of _____. They are __________ which means they can be easily undone. In a physical change, no new material is formed. If you heat bread it will _____ and become toast. Burning is a ________ c ...
DRUGS FINAL2
... suppression. Compared to morphine, codeine produces less analgesia, sedation, and respiratory depression, and is usually taken orally. It is made into tablets either alone (Schedule II) or in combination with aspirin or acetaminophen (i.e., Tylenol with Codeine, Schedule III). As a cough suppressant ...
... suppression. Compared to morphine, codeine produces less analgesia, sedation, and respiratory depression, and is usually taken orally. It is made into tablets either alone (Schedule II) or in combination with aspirin or acetaminophen (i.e., Tylenol with Codeine, Schedule III). As a cough suppressant ...
II. Classification of Matter
... Scientific (natural) _____________: a general statement based on the observed behavior of matter to which no exceptions are known. __________________: a broad generalization that explains a body of facts or phenomena. Quantitative vs. qualitative data Quantitative: numerical (_______________________ ...
... Scientific (natural) _____________: a general statement based on the observed behavior of matter to which no exceptions are known. __________________: a broad generalization that explains a body of facts or phenomena. Quantitative vs. qualitative data Quantitative: numerical (_______________________ ...
Potentially inappropriate drug use and hip
... not safer than traditional alternatives with regard to hip fractures Non-pharmacological treatment options Be aware of fall risk and possible effects on bone tissue Haney 2010, Bondesson 2013, Dalleur 2014 Follow-up ...
... not safer than traditional alternatives with regard to hip fractures Non-pharmacological treatment options Be aware of fall risk and possible effects on bone tissue Haney 2010, Bondesson 2013, Dalleur 2014 Follow-up ...
Medicine and Drugs Notes Using Drugs Drugs are used to ______
... lungs and passed through tiny blood vessels into the bloodstream. ALL smoke contains poisonous substances. It can cause lung cancer, lung disease, emphysema, and much more. Inhaling Drugs: People who have asthma use an inhaler to breath in the drug. Each time the inhaler is pumped, a _________ amoun ...
... lungs and passed through tiny blood vessels into the bloodstream. ALL smoke contains poisonous substances. It can cause lung cancer, lung disease, emphysema, and much more. Inhaling Drugs: People who have asthma use an inhaler to breath in the drug. Each time the inhaler is pumped, a _________ amoun ...
ONE-COMPARTMENT OPEN MODEL: INTRAVENOUS BOLUS
... the cumulative drug excreted versus time will yield a curve that approaches an asymptote at "infinite" time (∞). In practice, approximately seven elimination half-lives are needed for 99% of the drug to be eliminated. 5. Variations in urinary pH and volume may cause significant variation in urinary ...
... the cumulative drug excreted versus time will yield a curve that approaches an asymptote at "infinite" time (∞). In practice, approximately seven elimination half-lives are needed for 99% of the drug to be eliminated. 5. Variations in urinary pH and volume may cause significant variation in urinary ...
Salomon Z
... assume that such strategies would yield novel compounds with useful therapeutic properties, and hopefully, with fewer side effects because the pharmacological responses of pre-synaptic drugs are gradual and moderate while an effect originating postsynaptically may be of greater biological significan ...
... assume that such strategies would yield novel compounds with useful therapeutic properties, and hopefully, with fewer side effects because the pharmacological responses of pre-synaptic drugs are gradual and moderate while an effect originating postsynaptically may be of greater biological significan ...
drug elimination ii
... and excretion of drugs • Anatomically, the intra hepatic bile ducts join outside the liver to form the common hepatic duct. The bile that enters the gall bladder becomes highly concentrated • The hepatic duct, containing hepatic bile, join the cystic duct that drains the gallbladders to form the com ...
... and excretion of drugs • Anatomically, the intra hepatic bile ducts join outside the liver to form the common hepatic duct. The bile that enters the gall bladder becomes highly concentrated • The hepatic duct, containing hepatic bile, join the cystic duct that drains the gallbladders to form the com ...
NURS 1011-Pharmacology I Online Syllabus
... I can’t figure out what is important, so I try to write down everything said. I have a class that is mostly discussion-no idea what to write in my notes. I leave important information out of my notes and it often shows up on tests. One of my instructors jumps all over the place and I can’t follow wh ...
... I can’t figure out what is important, so I try to write down everything said. I have a class that is mostly discussion-no idea what to write in my notes. I leave important information out of my notes and it often shows up on tests. One of my instructors jumps all over the place and I can’t follow wh ...
metoprolol succinate - McGraw-Hill
... ● Tell patient that extended-release tablets are scored and can be divided, but that he should swallow tablets or half-tablets whole and not crush or chew them. 2Advise patients with heart failure to report signs or symptoms of worsening condition, including weight gain and increasing shortness of b ...
... ● Tell patient that extended-release tablets are scored and can be divided, but that he should swallow tablets or half-tablets whole and not crush or chew them. 2Advise patients with heart failure to report signs or symptoms of worsening condition, including weight gain and increasing shortness of b ...
Bacteria and mycobacteria
... Antibiotics that Affect Protein Synthesis • A protein synthesis inhibitor is a substance that stops or slows the growth or proliferation of cells by disrupting the processes that lead directly to the generation of new proteins in the cell. • It usually refers to antibiotics that act at the ribosome ...
... Antibiotics that Affect Protein Synthesis • A protein synthesis inhibitor is a substance that stops or slows the growth or proliferation of cells by disrupting the processes that lead directly to the generation of new proteins in the cell. • It usually refers to antibiotics that act at the ribosome ...
Drug Nomenclature
... and molecular structure • Generic name — assigned by the manufacturer that first develops the drug • Official name — name by which it is identified in official publications USP and NF • Trade name — brand name copyrighted by the company that sells the drug ...
... and molecular structure • Generic name — assigned by the manufacturer that first develops the drug • Official name — name by which it is identified in official publications USP and NF • Trade name — brand name copyrighted by the company that sells the drug ...
Chapter 14 Ionic and Covalent Compounds/ Organic compounds
... chemical activities, _________ and ______ materials, build and repair body structures, and regulate processes. -_ _________ Acids -The largest molecules made by living organisms are nucleic acids. Nucleic acids are bio-chemicals made up of ___________. Nucleotides are molecules made of carbon, hydro ...
... chemical activities, _________ and ______ materials, build and repair body structures, and regulate processes. -_ _________ Acids -The largest molecules made by living organisms are nucleic acids. Nucleic acids are bio-chemicals made up of ___________. Nucleotides are molecules made of carbon, hydro ...
General Principles - My Illinois State
... drug dose: the patient needs more drug to produce the same effect. ...
... drug dose: the patient needs more drug to produce the same effect. ...
CHEM 125 - CSB/SJU
... CHEM 125 is the introductory chemistry course. Students study atoms and their electron configuration, building a progressive and linked understanding of bonding, ionic and molecular geometry. Since chemical properties are dependent on electron distribution, students develop an understanding of molec ...
... CHEM 125 is the introductory chemistry course. Students study atoms and their electron configuration, building a progressive and linked understanding of bonding, ionic and molecular geometry. Since chemical properties are dependent on electron distribution, students develop an understanding of molec ...
Chemical Reactions - Mr. Brown`s Science Town
... Single Elements – write the symbol for element w/o a subscript. Example: Aluminum metal Al(s) b. Diatomic Element (7) - Write symbol for element w/ a subscript of 2; Hydrogen, Nitrogen, Oxygen, Fluorine, Chlorine, Bromine and Iodine Example: Chlorine gas Cl2(g) a. ...
... Single Elements – write the symbol for element w/o a subscript. Example: Aluminum metal Al(s) b. Diatomic Element (7) - Write symbol for element w/ a subscript of 2; Hydrogen, Nitrogen, Oxygen, Fluorine, Chlorine, Bromine and Iodine Example: Chlorine gas Cl2(g) a. ...
Conformational aspects of drug-DNA interactions: Studies on
... perhaps for compound V, which exhibits a planar moiety of only two condensed rings and is therefore expected to overlap less efficiently with the DNA base-pairs. Incidentally, it shows very poor, if any, biological activity (Antonello et al., 1979). Enhancement in specific viscosity of sonicated rod ...
... perhaps for compound V, which exhibits a planar moiety of only two condensed rings and is therefore expected to overlap less efficiently with the DNA base-pairs. Incidentally, it shows very poor, if any, biological activity (Antonello et al., 1979). Enhancement in specific viscosity of sonicated rod ...
Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Later chemical libraries of synthetic small molecules, natural products or extracts were screened in intact cells or whole organisms to identify substances that have a desirable therapeutic effect in a process known as classical pharmacology. Since sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease modifying in a process known as reverse pharmacology. Hits from these screens are then tested in cells and then in animals for efficacy.Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability. Once a compound that fulfills all of these requirements has been identified, it will begin the process of drug development prior to clinical trials. One or more of these steps may, but not necessarily, involve computer-aided drug design. Modern drug discovery is thus usually a capital-intensive process that involves large investments by pharmaceutical industry corporations as well as national governments (who provide grants and loan guarantees). Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, ""expensive, difficult, and inefficient process"" with low rate of new therapeutic discovery. In 2010, the research and development cost of each new molecular entity (NME) was approximately US$1.8 billion. Drug discovery is done by pharmaceutical companies, with research assistance from universities. The ""final product"" of drug discovery is a patent on the potential drug. The drug requires very expensive Phase I, II and III clinical trials, and most of them fail. Small companies have a critical role, often then selling the rights to larger companies that have the resources to run the clinical trials.Discovering drugs that may be a commercial success, or a public health success, involves a complex interaction between investors, industry, academia, patent laws, regulatory exclusivity, marketing and the need to balance secrecy with communication. Meanwhile, for disorders whose rarity means that no large commercial success or public health effect can be expected, the orphan drug funding process ensures that people who experience those disorders can have some hope of pharmacotherapeutic advances.