phytopharmacological aspects of chlorophytum borivilianum
... used in the treatment of many clinical conditions in India. It is an important drug commonly known as 'Safed Musli'. It has many therapeutic applications in Ayurvedic, Unani, Homeopathic and Allopathic system of medicine. In the Ayurvedic literature, Safed Musli is celebrated as a Divya Aushad with ...
... used in the treatment of many clinical conditions in India. It is an important drug commonly known as 'Safed Musli'. It has many therapeutic applications in Ayurvedic, Unani, Homeopathic and Allopathic system of medicine. In the Ayurvedic literature, Safed Musli is celebrated as a Divya Aushad with ...
Drugs and the Elderly: Practical Considerations
... Average prescription drug cost for an older person is $500/year, but highly variable Nonprescription drugs and herbals can be quite expensive Many Medicare Managed Care Plans have dropped or severely limited drug coverage Drugs cost more in US than any other country New drugs cost more UCSF Division ...
... Average prescription drug cost for an older person is $500/year, but highly variable Nonprescription drugs and herbals can be quite expensive Many Medicare Managed Care Plans have dropped or severely limited drug coverage Drugs cost more in US than any other country New drugs cost more UCSF Division ...
WIPO IPC: Internet Publication
... o Non-metals: H, B, C, Si, N, P, O, S, Se, Te, noble gases, halogens o Metals: elements other than non-metals o Transition elements: elements with atomic numbers 21 to 30 inclusive, 39 to 48 inclusive, 57 to 80 inclusive, 89 upwards Section C covers : o pure chemistry, which covers inorganic compoun ...
... o Non-metals: H, B, C, Si, N, P, O, S, Se, Te, noble gases, halogens o Metals: elements other than non-metals o Transition elements: elements with atomic numbers 21 to 30 inclusive, 39 to 48 inclusive, 57 to 80 inclusive, 89 upwards Section C covers : o pure chemistry, which covers inorganic compoun ...
Pharmacological Effects of Rutaecarpine, an Alkaloid Isolated from
... by accidents. Currently available cerebral metabolic activators and cerebrovasodilators used for the treatment of disorders following cerebral infarction and cerebral hemorrhage, as well as cerebral arteriosclerosis, are recognized as having antianoxic action (24). Brain tissue has a very high oxyge ...
... by accidents. Currently available cerebral metabolic activators and cerebrovasodilators used for the treatment of disorders following cerebral infarction and cerebral hemorrhage, as well as cerebral arteriosclerosis, are recognized as having antianoxic action (24). Brain tissue has a very high oxyge ...
Fluoroquinolone resistance in mycobacterium tuberculosis strains
... ciprofloxacin (CIP)2. The first three of these drugs are commonly known as anti-pneumococcal fluoroquinolones used in community-acquired pneumonia. MTB clinical isolates that demonstrate highlevel phenotypic resistance to fluoroquinolones, which appears to be predominantly due to gyrA mutations, exh ...
... ciprofloxacin (CIP)2. The first three of these drugs are commonly known as anti-pneumococcal fluoroquinolones used in community-acquired pneumonia. MTB clinical isolates that demonstrate highlevel phenotypic resistance to fluoroquinolones, which appears to be predominantly due to gyrA mutations, exh ...
Quick guide to drugs and alcohol
... » Motivational enhancement is an approach used by the therapist to help the client to decide for themselves that they really need to change their behaviour. This can help maintain commitment in people who might otherwise leave treatment before it can be effective. » Cognitive behavioural therapy see ...
... » Motivational enhancement is an approach used by the therapist to help the client to decide for themselves that they really need to change their behaviour. This can help maintain commitment in people who might otherwise leave treatment before it can be effective. » Cognitive behavioural therapy see ...
Urine Drug Screening: Practical Guide for Clinicians
... Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common method for analysis because of ease of sampling. The simplicity of use and access to rapid results have increased demand for and us ...
... Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common method for analysis because of ease of sampling. The simplicity of use and access to rapid results have increased demand for and us ...
The Drug Regimen Review
... The facility is expected to have a proactive, systematic and effective approach to monitoring, reporting, and acting upon the effects, risks, and adverse consequences of medications. The pharmacist may need to conduct the medication regimen review more frequently (for example weekly), depending on t ...
... The facility is expected to have a proactive, systematic and effective approach to monitoring, reporting, and acting upon the effects, risks, and adverse consequences of medications. The pharmacist may need to conduct the medication regimen review more frequently (for example weekly), depending on t ...
IOSR Journal of Pharmacy and Biological Sciences (IOSRJPBS)
... synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such asautolysins; it is possible that flucloxacillin interferes with an autolysin inhibitor.. Literature survey revealed that FLUCLOXACILLIN was estimated either individually or in presence of amoxicillin trihydrate by ...
... synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such asautolysins; it is possible that flucloxacillin interferes with an autolysin inhibitor.. Literature survey revealed that FLUCLOXACILLIN was estimated either individually or in presence of amoxicillin trihydrate by ...
Urine Drug Screening: Practical Guide for Clinicians
... Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common method for analysis because of ease of sampling. The simplicity of use and access to rapid results have increased demand for and us ...
... Drug testing, commonly used in health care, workplace, and criminal settings, has become widespread during the past decade. Urine drug screens have been the most common method for analysis because of ease of sampling. The simplicity of use and access to rapid results have increased demand for and us ...
Drugs to Prevent Bone Fractures in People with Osteoporosis
... Menopausal hormone therapy does not reduce the risk of fractures in women diagnosed with osteoporosis. And it actually increases the risk of stroke, heart disease, and breast cancer, so it’s generally not used solely to treat or prevent osteoporosis. Only a few studies have compared bisphosphonates ...
... Menopausal hormone therapy does not reduce the risk of fractures in women diagnosed with osteoporosis. And it actually increases the risk of stroke, heart disease, and breast cancer, so it’s generally not used solely to treat or prevent osteoporosis. Only a few studies have compared bisphosphonates ...
therapeutics i
... personnel who work in an inpatient setting, while other journals are designed for those who work in an outpatient environment. d. To meet your individual needs, you should become familiar with some frequently used pharmacy journals, the type of information each contains, and the particular group(s) ...
... personnel who work in an inpatient setting, while other journals are designed for those who work in an outpatient environment. d. To meet your individual needs, you should become familiar with some frequently used pharmacy journals, the type of information each contains, and the particular group(s) ...
Simultaneous Spectrophotometric Determination of Drotaverine
... Wankhede et al.: Simultaneous Estimation of Amlodipine, Losartan and Hydrochlorthiazide Two UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazid ...
... Wankhede et al.: Simultaneous Estimation of Amlodipine, Losartan and Hydrochlorthiazide Two UV-spectrophotometric and one reverse phase high performance liquid chromatography methods have been developed for the simultaneous estimation of amlodipine besilate, losartan potassium and hydrochlorothiazid ...
Steroids - Montana Narcotics Officers Association
... Although different types of steroids exist naturally in humans, the drugs commonly known as anabolic steroids are synthetic chemical compounds designed to create certain effects that natural hormones cause in the body. Steroid is the generic name given to compounds having a basic ring structure simi ...
... Although different types of steroids exist naturally in humans, the drugs commonly known as anabolic steroids are synthetic chemical compounds designed to create certain effects that natural hormones cause in the body. Steroid is the generic name given to compounds having a basic ring structure simi ...
PESTICIDE DEGRADATION
... up a layer of mercury in the soil from continual use of mercury have on plant growth? Or more important, since mercury is not readily removed from the human body, what effect is continual exposure having on you? My personal philosophy is that we are in the business of maintaining healthy plants, and ...
... up a layer of mercury in the soil from continual use of mercury have on plant growth? Or more important, since mercury is not readily removed from the human body, what effect is continual exposure having on you? My personal philosophy is that we are in the business of maintaining healthy plants, and ...
Zebrafish as tools for drug discovery
... rone, which remains the definitive antiarrhythmic agent decades after its serendipitous discovery, exhibits activity on multiple ion channels, adrenergic receptors, and possibly even nuclear hormone pathways4. In addition, there is evidence that the acute effects of the intravenous form may be attri ...
... rone, which remains the definitive antiarrhythmic agent decades after its serendipitous discovery, exhibits activity on multiple ion channels, adrenergic receptors, and possibly even nuclear hormone pathways4. In addition, there is evidence that the acute effects of the intravenous form may be attri ...
Detoxification of Metals – Biochelation
... Lead Exposure to lead via inhalation may occur in certain occupational environments. The addition of alkyl lead compounds to gasoline is also a source of lead exposure via inhalation. The general population is mainly exposed to lead from food (either through the food items or through contamination o ...
... Lead Exposure to lead via inhalation may occur in certain occupational environments. The addition of alkyl lead compounds to gasoline is also a source of lead exposure via inhalation. The general population is mainly exposed to lead from food (either through the food items or through contamination o ...
Estimating the “First in human” dose – a revisit with particular
... type of compound in human at the time and a small amount of published data were available before the clinical investigation. Similar clinical trials of antibodies against T cell antigens had already shown toxic effects [14], suggesting that the TGN1412 trial would be a high-risk study. In the TGN141 ...
... type of compound in human at the time and a small amount of published data were available before the clinical investigation. Similar clinical trials of antibodies against T cell antigens had already shown toxic effects [14], suggesting that the TGN1412 trial would be a high-risk study. In the TGN141 ...
ordinary level chemistry syllabus
... 1.2.1. Chemistry and society Chemistry, one of the natural science subjects, is an important discipline that has contributed significantly to the global socio-economic transformation. This level of contribution has been achieved through the range of important life changing discoveries by chemists. T ...
... 1.2.1. Chemistry and society Chemistry, one of the natural science subjects, is an important discipline that has contributed significantly to the global socio-economic transformation. This level of contribution has been achieved through the range of important life changing discoveries by chemists. T ...
Chapter 2: Atoms, Molecules and Ions
... • The electrostatic forces that hold cations and anions together in an extended array (a lattice) are STRONG! • As a result of these strong attractive forces, ALL ionic compounds are solids at room temperature. (Ionic Compounds have high melting points.) • Solid ionic compounds DO NOT conduct electr ...
... • The electrostatic forces that hold cations and anions together in an extended array (a lattice) are STRONG! • As a result of these strong attractive forces, ALL ionic compounds are solids at room temperature. (Ionic Compounds have high melting points.) • Solid ionic compounds DO NOT conduct electr ...
in for a penny, in for the pounds
... subcutaneously in the shoulder area of cattle, a polymeric PLGA matrix is formed. The biodegradable matrix solidifies in vivo to form an in situ forming gel, which allows a gradual release of eprinomectin from the formulation. The rate-limiting step is diffusion of the drug through the gel matrix. B ...
... subcutaneously in the shoulder area of cattle, a polymeric PLGA matrix is formed. The biodegradable matrix solidifies in vivo to form an in situ forming gel, which allows a gradual release of eprinomectin from the formulation. The rate-limiting step is diffusion of the drug through the gel matrix. B ...
et al. Madhu E. Nicholas* , Shanker Panaganti , L. Prabakaran
... knowledge of the anatomy and physiology of GIT is required. The GI tract is divided into stomach, small intestine and large intestine. In GIT, the large intestine extending from the ileocecal junction to the anus is divided in to three main parts. These are the colon, the rectum and anal canal. The ...
... knowledge of the anatomy and physiology of GIT is required. The GI tract is divided into stomach, small intestine and large intestine. In GIT, the large intestine extending from the ileocecal junction to the anus is divided in to three main parts. These are the colon, the rectum and anal canal. The ...
BACHELOR OF SCIENCE IN CHEMISTRY MINOR IN BUSINESS
... The scope of this course includes the analysis and characterization of the structure of simple and complex monosaccharides, oligosaccharides and polysaccharides, including sequence, linkages, configuration, conformation, functional groups, polymerization, derivatization and degradation. Important pa ...
... The scope of this course includes the analysis and characterization of the structure of simple and complex monosaccharides, oligosaccharides and polysaccharides, including sequence, linkages, configuration, conformation, functional groups, polymerization, derivatization and degradation. Important pa ...
Anti-HIV drugs: 25 compounds approved within 25 years after the
... be foreseen that within 25 years of the virus being discovered we would now, in 2008, have at hand 25 anti-HIV compounds licensed (thus formally approved) for the treatment of AIDS (Table 1). These compounds fall within different categories depending on the target within the HIV replicative cycle th ...
... be foreseen that within 25 years of the virus being discovered we would now, in 2008, have at hand 25 anti-HIV compounds licensed (thus formally approved) for the treatment of AIDS (Table 1). These compounds fall within different categories depending on the target within the HIV replicative cycle th ...
Trends in Retail Prices of Brand Name Prescription Drugs
... TRENDS IN RETAIL PRICES OF BRAND NAME PRESCRIPTION DRUGS WIDELY USED BY OLDER AMERICANS, 2006–2015 ...
... TRENDS IN RETAIL PRICES OF BRAND NAME PRESCRIPTION DRUGS WIDELY USED BY OLDER AMERICANS, 2006–2015 ...
Drug discovery
In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Later chemical libraries of synthetic small molecules, natural products or extracts were screened in intact cells or whole organisms to identify substances that have a desirable therapeutic effect in a process known as classical pharmacology. Since sequencing of the human genome which allowed rapid cloning and synthesis of large quantities of purified proteins, it has become common practice to use high throughput screening of large compounds libraries against isolated biological targets which are hypothesized to be disease modifying in a process known as reverse pharmacology. Hits from these screens are then tested in cells and then in animals for efficacy.Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability. Once a compound that fulfills all of these requirements has been identified, it will begin the process of drug development prior to clinical trials. One or more of these steps may, but not necessarily, involve computer-aided drug design. Modern drug discovery is thus usually a capital-intensive process that involves large investments by pharmaceutical industry corporations as well as national governments (who provide grants and loan guarantees). Despite advances in technology and understanding of biological systems, drug discovery is still a lengthy, ""expensive, difficult, and inefficient process"" with low rate of new therapeutic discovery. In 2010, the research and development cost of each new molecular entity (NME) was approximately US$1.8 billion. Drug discovery is done by pharmaceutical companies, with research assistance from universities. The ""final product"" of drug discovery is a patent on the potential drug. The drug requires very expensive Phase I, II and III clinical trials, and most of them fail. Small companies have a critical role, often then selling the rights to larger companies that have the resources to run the clinical trials.Discovering drugs that may be a commercial success, or a public health success, involves a complex interaction between investors, industry, academia, patent laws, regulatory exclusivity, marketing and the need to balance secrecy with communication. Meanwhile, for disorders whose rarity means that no large commercial success or public health effect can be expected, the orphan drug funding process ensures that people who experience those disorders can have some hope of pharmacotherapeutic advances.