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Steroids: The Brain`s Response
Steroids: The Brain`s Response

... Steroids are able to alter the functioning of many organs, including the liver, kidneys, heart, and brain. They can also have a profound effect on reproductive organs and hormones. Many of the effects of steroids are brought about through their actions in the brain. Once steroids enter the brain, th ...
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... The Somatic Nervous System: Receives sensory information from the sensory organs and controls movements of the skeletal muscles for voluntary and involuntary behavior. The Autonomic Nervous System: The regulation of the smooth muscles, cardiac muscle and glands. The function of the Autonomic Nervous ...
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The Nervous System - Liberty Union High School District
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... Norepinephrine-Serotonin agonists, and, finally SSRIs act as Serotonin (5-HT) agonists. Thus, the monoamine hypothesis has evolved in the same way, so that today one popular theory of depression, the Monoamine Hypothesis, is that depression is the result of underactivity of monoamines, especially 5- ...
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embj201593518-sup-0001

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Modulation of Responses of Feline Ventral Spinocerebellar Tract
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... were tested for the effects of ionophoretically applied monoamines and receptor selective agonists. Extracellularly recorded responses, monosynaptically evoked by group I afferents in a muscle nerve, were compared before, during, and after ionophoresis. They were analyzed with respect to changes in ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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