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Beyond Spikes: Neural Codes and the Chemical Vocabulary of
Beyond Spikes: Neural Codes and the Chemical Vocabulary of

... research, which we will refer to by the more general term connectionism, does not concern itself too much with biological realism, so the “neuron” states do not have to correspond to anything an actual cell has to deal with. Even in these cases, though, some of the biological language is preserved. ...
Release of chemical transmitters from cell bodies and dendrites of
Release of chemical transmitters from cell bodies and dendrites of

... in the presynaptic membrane [17], the molecular mechanisms for docking and fusion [18,19] and the number of vesicles that release transmitter per impulse [20]. A major advance is that one can observe presynaptic steps in the release mechanism by electron microscopic tomography [21]. Thin sections of ...
The Autonomic Nervous System and Visceral Reflexes
The Autonomic Nervous System and Visceral Reflexes

... have excitatory on some target cells and inhibitory ...
Chapter 15
Chapter 15

... Preganglionic neuron ascends or descends to another ganglion along sympathetic chain before synapsing with postganglionic neuron. An axon may project through a ganglion and synapse with a postglanglionic neuron in one of the prevertebral ganglia. Preganglionic sympathetic fibers synapse on the adren ...
Chapter Two Line Title Here and Chapter Title Here and Here
Chapter Two Line Title Here and Chapter Title Here and Here

... a. Circuits that control locomotion or repetitive motor activity are called central pattern generators (CPGs), consisting of inhibitory and excitatory neurons that produce rhythmic or alternating movements. 2. The projection level has direct control of the spinal cord and acts on direct and indirect ...
Taste & Smell Pre-lab Web questions
Taste & Smell Pre-lab Web questions

... 8.Describe the path odor molecules take from inhalation to behavior. • Odor molecules entering the nose are thought to be recognized by receptors found in cilia of olfactory neurons. • Neurons with specific receptors are arranged randomly within zones in the olfactory lining of the nasal cavity. • ...
Minireview: Role of Glia in Neuroendocrine Function
Minireview: Role of Glia in Neuroendocrine Function

... of synaptic contacts (5). For instance, estradiol reorganizes astrocytic laminin into extracellular fibrillar arrays that facilitate neurite extension (12), although the precise mechanisms of the estrogen effect on laminin have not been established. The hormone also increases expression of TrkA rece ...
Douglas B. Webster and Molly Webster
Douglas B. Webster and Molly Webster

... non-NMDA-type ionotropic receptor for glutamate that mediates fast synaptic transmission in the central nervous system (CNS). Its name is derived from its ability to be activated by the artificial glutamate analog, AMPA. AMPARs are found in many parts of the brain and are the most commonly found rec ...
Physiological role of insulin
Physiological role of insulin

... – Increased lipoprotein metabolism • Lipoprotein lipase – Increased free fatty acids release ...
Sensory Systems
Sensory Systems

... • receptors synapse with –bipolar cells –horizontal cells • bipolar cells synapse with –ganglion cells –amacrine cells • ganglion cell axons form the optic nerve ...
The Autonomic Nervous System
The Autonomic Nervous System

... There is no parasympathetic input to sweat glands, arrector pili muscles, smooth muscle in the walls of blood vessels of the skin or skeletal muscle – these are all sympathetic. Parasympathetic nuclei in the brain stem (=cranial) ...
neurotransmitters
neurotransmitters

... POTENTIALS (Aps).  Only cells with excitable membranes (like muscle cells and neurons) can generate APs. ...
The Physics of the Brain
The Physics of the Brain

... the fall time. Or the even simpler ‘alpha’ function: ...
Chapt13 Lecture 13ed Pt 2
Chapt13 Lecture 13ed Pt 2

... Synaptic integration • Integration is the _____________ of the inhibitory and excitatory signals received by a postsynaptic neuron. • This occurs because a neuron receives many signals. ...
Ominous odors: olfactory control of instinctive fear and aggression in
Ominous odors: olfactory control of instinctive fear and aggression in

... aggressive and fearful responses across individuals without previous experience and learning indicates that the underlying neural correlates are in part genetically determined, which may provide experimental traction. For example, these specialized ligands activate unknown subsets of sensory recepto ...
Nervous System
Nervous System

... Nervous System and Drugs continued 3. Invertebrates do not have myelinated axons. However, some invertebrates, such as squid, have giant nerve fibers with axons up to 1 mm in diameter. Other large diameter axons are found in crayfish and earthworms. Explain why these organisms have large axons. Pred ...
PRESYNAPTIC IONOTROPIC RECEPTORS AND CONTROL OF
PRESYNAPTIC IONOTROPIC RECEPTORS AND CONTROL OF

... action potential. The associated membrane depolarization activates voltage-gated Ca2+-channels (VGCCs) within the terminal, including channels that are strategically placed near vesicle docking sites. Ca2+ entry stimulates release by promoting fusion of synaptic vesicles with the plasma membrane. Ac ...
Psychopharmacology
Psychopharmacology

... two classes of these inverse agonists • Cause extreme anxiety and sense of panic when administered to humans ...
Smell and Taste
Smell and Taste

...  Stimulated by chemicals in solution  Taste has four types of receptors  Smell can differentiate a large range of chemicals ...
neuroloc
neuroloc

... The LSO calculates IID by subtracting the response of the contralateral ear from the response of the ipsilateral ear using inhibition. By adjusting the amount of inhibition delivered by MNTB, can make different LSO neurons respond over different ranges of IIDs. ...
Slide 1 - Elsevier
Slide 1 - Elsevier

... FIGURE 13.5 The vitamin D receptor (VDR). (A) Organization of the VDR chromosomal gene. The human VDR gene is located on chromosome 12q13-14 and spans approximately 60 kilobases of DNA. The gene is composed of at least 5 noncoding exons and 8 coding exons. Alternative splicing results in at least 1 ...
Chapter 48: Neurons, Synapses, and Signaling 48.1: Neuron
Chapter 48: Neurons, Synapses, and Signaling 48.1: Neuron

...  Response depends on kind of receptor expressed by postsynaptic cell  One neurotransmitter can bind to multiple types of receptors  Acetylcholine involved in muscle stimulation, memory formation, learning o Ligand-gated ion channel type functions at neuromuscular junction where motor neurons syna ...
Linear associator
Linear associator

... system. We know if a tone is consistently presented at the same time as food, the dog will eventually become conditioned to respond by salivating to the tone alone. In the previous lab, we hypothesized that this may have been due to neurons of the auditory system forming synapses directly onto the c ...
Principles of Neural Science
Principles of Neural Science

... Electrical synaptic transmission was first described in the giant motor synapse of the crayfish, where the presynaptic fiber is much larger than the postsynaptic fiber (Figure 10-2A). An action potential generated in the presynaptic fiber produces a depolarizing post- synaptic potential that is ofte ...
doc GIT
doc GIT

... 2- Myenteric plexus - b/w the circular and longitudinal muscle Structurally they are different; but for our purposes, the plexuses are considered as 1: ~ enteric plexus/innervation - a functional unit that comprises the submucosal and myenteric plexus. This is b/c there are too many connections b/w ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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