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somatic sensation
somatic sensation

... Following tissue damage and nociceptor stimulation, the threshold for subsequent stimulation is decreased and thus, sensitivity to that stimulus is increased. This process is termed “hyperalgesia”. In some cases, hyperalgesia can induce a change in nociceptor sensitivity from unimodal to bimodal, e. ...
Attenuating GABAA Receptor Signaling in Dopamine Neurons
Attenuating GABAA Receptor Signaling in Dopamine Neurons

... How did they do it?  Locomotion ...
01. Sensory
01. Sensory

... construed to be the primary odorants); current consensus recognizes many more, based upon identified anosmias and genes identified that code for olfactory receptors • served by cranial nerve I (olfactory nerve): hair cells synapse within olfactory bulb (table 13 – 2) with afferent neurons which tran ...
Autonomic Nervous System Period 5 Jacquelene Hanein, Karina
Autonomic Nervous System Period 5 Jacquelene Hanein, Karina

... ● CNS + PNS = ANS ● Parasympathetic neurons: sacral region in spinal cord + medulla oblongata, pons, brainstem, midbrain ● Sympathetic neurons: body of spinal cord ...
The Nervous System
The Nervous System

... Sensory receptors are specialized sensory cells that detect changes in blood pressure, strain on ligaments, and smells in the air, among other things. Complex sensory receptors made of many cell & tissue types are called sensory organs. ...
Lack of response suppression follows repeated ventral tegmental
Lack of response suppression follows repeated ventral tegmental

... firing rate. The increases in firing rate and the time to return to basal firing were not significantly different between exposures. Furthermore, the cannabinoid antagonist SR141716A completely prevented the HU210-induced excitation whilst having no effect on its own, thus indicating a CB1-receptor ...
File
File

... on a wide range of bodily functions and also impact emotions. When they act on the brain, they influence our interest in sex, food, and aggression. A special type of hormone called ...
File
File

... transmitters in the brain whereas caffeine causes nerve impulses to be sent ______, thereby _______ reaction time. Serotonin is a neurotransmitter in the central nervous system that is associated with feeling ____. The drug ecstasy blocks the synapses where the serotonin is removed, making the feeli ...
Opium Poppy - thblack.com
Opium Poppy - thblack.com

... these receptors are endorphins and enkephalins (small peptides) These peptides are released at synapses on neurons involved in transmitting pain signals to the brain ...
II Sensory - Washington State University
II Sensory - Washington State University

... there are 2… • 1. Adenyl cyclase pathway: G protein activation leads to activation of adenyl cyclase. Cyclic AMP opens cation channels admitting Na+ and Ca++. The Ca++ then opens a Cl- channel that further depolarizes the cell. • 2. IP3 pathway: The activated G protein activates phospholipase C whic ...
Model Description Sheet
Model Description Sheet

... has the ability to stimulate cellular signaling pathways that makes MOP-based painkillers rewarding. An alternate target that alleviates pain but does not produce reward is the kappa opioid receptor (KOP). Unfortunately, many KOP agonists also activate intracellular signaling pathways that produce h ...
Anatomy and Physiology
Anatomy and Physiology

... Chronic (slow) – Begins after a second or more and increases in intensity; aka burning, throbbing, aching pain. It can be excruciating - Can be in skin, deeper tissues viscera. ...
Excitatory and inhibitory transmission in the superior olivary complex
Excitatory and inhibitory transmission in the superior olivary complex

... Synaptic release of glutamate activates both AMPA and NMDA receptors generating a dual component excitatory postsynaptic current (EPSC) at the MNTB (Barnes-Davies and Forsythe 1995). The fast component is mediated by AMPA receptors while a slow component is mediated NMDA receptors. The NMDA receptor ...
Lecture-08-2013-Bi
Lecture-08-2013-Bi

... The pentameric GABAA and glycine receptors look like ACh receptors; but they are permeable to anions (mostly Cl-, of course) 1. -amino-butyric acid (GABA) is the principal inhibitory transmitter in the brain. 2. Glycine is the dominant inhibitory transmitter in the spinal cord & hindbrain. GABAA r ...
Application Six - Sheila Tooker Impey
Application Six - Sheila Tooker Impey

... left side of his face, because of the neural damage to the right precentral gyrus which is the location of the primary motor cortex that controls voluntary movement. Most normal functioning neurons receive chemical signals from the axon termini of other neurons (Freeman, 2000). There is then an acti ...
Nervous System - EMTStudyCenter.com
Nervous System - EMTStudyCenter.com

... 4. The portion of the nervous system that is considered involuntary is the somatic nervous system. sensory nervous system. autonomic nervous system. motor nervous system. 5. All of the following are functions of the nervous system EXCEPT senses changes. analyzes changes. ...
Nervous Tissue
Nervous Tissue

... The part of the neuron which immediately surrounds the nucleus Usually used synonymously with neuron or soma ...
Brains, Synapses and Neurotransmitters
Brains, Synapses and Neurotransmitters

... how the nervous system works The nervous system is made up, basically, of two types of cells • Neurons ...
Chapter 10 Somatic and Special Senses
Chapter 10 Somatic and Special Senses

... _____________ pain occurs because of the common nerve pathways leading from skin and internal organs. An example would be a heart attack being felt as pain in the arm or as heartburn. What is the difference between acute and chronic pain? How do their neurons differ? Regulation of pain: A person be ...
Neurotransmitters
Neurotransmitters

... • NMDA receptor channels admit Ca ++ which can have important 2nd messenger effects • GLU is an abundant amino acid in the brain, maybe 30% of which is transmitter • Inactivation = reuptake by glia, conversion to glutamine, return to neuron terminal (where it can be reconverted to Glu) ...
ANS and sympathetic division pharm
ANS and sympathetic division pharm

... of cyclic AMP, activation of PKA, and altered function of numerous cellular proteins as a result of their phosphorylation. In addition, Gs can enhance directly the activation of voltage-sensitive Ca2+ channels in the plasma membrane of skeletal and cardiac muscle. ...
The Special Senses
The Special Senses

... that receives the information • Also depends on the sequence of neurons carrying the information ...
Savage Science AP Biology
Savage Science AP Biology

... Many sensory receptors are very sensitive: they are able to detect the smallest physical unit of stimulus – For example, most light receptors can detect a photon of light ...
Abstract of thesis: Agonist and antagonist interaction with AT1
Abstract of thesis: Agonist and antagonist interaction with AT1

... The octapeptide angiotensin II is the main peptide hormone of the renin-angiotensin system (RAS) and is known to be involved in the physiological and pathological regulation of blood pressure and cardiovascular function by stimulating AT1 receptors. Therapeutic agents that block the production of an ...
Psychopharmacology
Psychopharmacology

... • Consequently it is high carbohydrate and low protein diets that increases brain tryptophan levels – Insulin release is stimulated by high carb diet. – Insulin causes most amino acids to be removed from the blood ...
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Endocannabinoid system

The endocannabinoid system is a group of neuromodulatory lipids and their receptors in the brain that are involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory; it mediates the psychoactive effects of cannabis and, broadly speaking, includes: The endogenous arachidonate-based lipids, anandamide (N-arachidonoylethanolamide, AEA) and 2-arachidonoylglycerol (2-AG); these are known as ""endocannabinoids"" and are physiological ligands for the cannabinoid receptors. Endocannabinoids are all eicosanoids. The enzymes that synthesize and degrade the endocannabinoids, such as fatty acid amide hydrolase or monoacylglycerol lipase. The cannabinoid receptors CB1 and CB2, two G protein-coupled receptors that are located in the central and peripheral nervous systems.The neurons, neural pathways, and other cells where these molecules, enzymes, and one or both cannabinoid receptor types are all colocalized form the endocannabinoid system.The endocannabinoid system has been studied using genetic and pharmacological methods. These studies have revealed that cannabinoids act as neuromodulators for a variety of processes, including motor learning, appetite, and pain sensation, among other cognitive and physical processes. The localization of the CB1 receptor in the endocannabinoid system has a very large degree of overlap with the orexinergic projection system, which mediates many of the same functions, both physical and cognitive. Moreover, CB1 is colocalized on orexin projection neurons in the lateral hypothalamus and many output structures of the orexin system, where the CB1 and orexin receptor 1 (OX1) receptors physically and functionally join together to form the CB1–OX1 receptor heterodimer.
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