2-GENERAL PRINCIPLES FINAL
... regulatorymolecules, to stimulate or inhibit physiologic processes. ...
... regulatorymolecules, to stimulate or inhibit physiologic processes. ...
general pharmacology
... Advantages Rapid action (emergency) High bioavailability No food-drug interaction No first pass metabolism No gastric irritation Suitable for Vomiting &unconscious Irritant & Bad taste drugs. ...
... Advantages Rapid action (emergency) High bioavailability No food-drug interaction No first pass metabolism No gastric irritation Suitable for Vomiting &unconscious Irritant & Bad taste drugs. ...
Guidance regarding Psychoactive Substances
... NPS must not be brought on to Trust premises by either the service user or their visitors, and they must not be used during the course of treatment as they may prolong the illness or make it worse, or prevent other therapies from working. ...
... NPS must not be brought on to Trust premises by either the service user or their visitors, and they must not be used during the course of treatment as they may prolong the illness or make it worse, or prevent other therapies from working. ...
Introduction to Pharmacology
... – Pharmacy - the art and science of compounding and dispensing - and, increasingly, drug information... – Clinical pharmacology - the art and science of evaluating and optimizing the use of drugs in humans ...
... – Pharmacy - the art and science of compounding and dispensing - and, increasingly, drug information... – Clinical pharmacology - the art and science of evaluating and optimizing the use of drugs in humans ...
Practice slide 8 tafreeg 2
... Sometimes we may have a delay between PD interaction (displacement) and PD interaction (response) Interactions of phenytoin and warfarin: Phenytoin will displace the warfarin increase conc of warfarin (PK interaction) and this increase the PD interaction but we won't see this interaction because ...
... Sometimes we may have a delay between PD interaction (displacement) and PD interaction (response) Interactions of phenytoin and warfarin: Phenytoin will displace the warfarin increase conc of warfarin (PK interaction) and this increase the PD interaction but we won't see this interaction because ...
SUBSTANCE ABUSE AND ADDICTION BASIC INFORMATION
... • Disulfiram (Antabuse) for alcoholism. This drug produces severe illness when alcohol is consumed. • Naltrexone, which blocks the effect of opiates. • Methadone for narcotic abuse. This drug is a less potent narcotic that is used to decrease the severity of physical withdrawal symptoms or allows a ...
... • Disulfiram (Antabuse) for alcoholism. This drug produces severe illness when alcohol is consumed. • Naltrexone, which blocks the effect of opiates. • Methadone for narcotic abuse. This drug is a less potent narcotic that is used to decrease the severity of physical withdrawal symptoms or allows a ...
Drug Discovery Process
... • Patient feels better even if on placebo – Often seen with antidepressants, antianxiety meds ...
... • Patient feels better even if on placebo – Often seen with antidepressants, antianxiety meds ...
Slide 1 - AccessPharmacy
... This diagram illustrates the way in which two pharmacokinetic parameters (hepatic extraction ratio and percent plasma protein binding) are used to assign a drug into one of three classes of hepatic clearance (flow limited; capacity limited, binding sensitive; and capacity limited, binding insensitiv ...
... This diagram illustrates the way in which two pharmacokinetic parameters (hepatic extraction ratio and percent plasma protein binding) are used to assign a drug into one of three classes of hepatic clearance (flow limited; capacity limited, binding sensitive; and capacity limited, binding insensitiv ...
Study guide for Unit I - People Server at UNCW
... 4. What are the major routes of drug administration? Consider the advantages and disadvantages of each? 5. How are drugs absorbed? Define bioavailability. 6. How are drugs distributed to sites of action? What factors influence this? 7. How are drugs eliminated from the body? Define half-life. How lo ...
... 4. What are the major routes of drug administration? Consider the advantages and disadvantages of each? 5. How are drugs absorbed? Define bioavailability. 6. How are drugs distributed to sites of action? What factors influence this? 7. How are drugs eliminated from the body? Define half-life. How lo ...
specific indications
... by retail pharmacies, which may qualify as Part B drugs and those which may qualify as Part D drugs. At this time, Part B covers the oral anti-cancer, oral anti-emetic, and immunosuppressive drugs listed below under certain circumstances. This does not represent an exhaustive list of Part B covered ...
... by retail pharmacies, which may qualify as Part B drugs and those which may qualify as Part D drugs. At this time, Part B covers the oral anti-cancer, oral anti-emetic, and immunosuppressive drugs listed below under certain circumstances. This does not represent an exhaustive list of Part B covered ...
Using Drugs to Promote Health - Garnet Valley School District
... Drugs and the cells of the body are like keys and locks. ...
... Drugs and the cells of the body are like keys and locks. ...
Lecture Resource ()
... Distribution coefficient: the ratio of the amount dissolving in 1-octanol to the amount dissolving in water Compounds with a lower distribution coefficient cannot penetrate the cell membrane Compounds with a higher distribution coefficient cannot cross the aqueous phase ...
... Distribution coefficient: the ratio of the amount dissolving in 1-octanol to the amount dissolving in water Compounds with a lower distribution coefficient cannot penetrate the cell membrane Compounds with a higher distribution coefficient cannot cross the aqueous phase ...
W A R N I N G! - Rockytop Boxers
... for air or car travel. I would strongly recommend that Boxer owners avoid the use of this drug, especially when the dog will be unattended and/or unable to receive emergency medical care if it is needed. Submitted by Wendy Wallner, DVM July, 1997 If your vet needs more than your word that you do NOT ...
... for air or car travel. I would strongly recommend that Boxer owners avoid the use of this drug, especially when the dog will be unattended and/or unable to receive emergency medical care if it is needed. Submitted by Wendy Wallner, DVM July, 1997 If your vet needs more than your word that you do NOT ...
Designer and look
... • Designer drugs refers to the compounds produced in underground laboratories • Designer drugs refers to the alterations of existing drugs whose chemical structure is modified to mimic the effect of the parent drug. • Designer drugs are also called analogues or variations of hallucinogenic drugs. ...
... • Designer drugs refers to the compounds produced in underground laboratories • Designer drugs refers to the alterations of existing drugs whose chemical structure is modified to mimic the effect of the parent drug. • Designer drugs are also called analogues or variations of hallucinogenic drugs. ...
Internal Medicine Morning Report
... – Arthritis – Gastrointestinal disorders – Bladder dysfunction ...
... – Arthritis – Gastrointestinal disorders – Bladder dysfunction ...
Smoking & Drinking
... a few days earlier, enabling the blood to carry more oxygen – it is banned as it's a form of cheating as well as potentially causing kidney and heart failure • Beta blockers are banned in archery and shooting as they keep the ...
... a few days earlier, enabling the blood to carry more oxygen – it is banned as it's a form of cheating as well as potentially causing kidney and heart failure • Beta blockers are banned in archery and shooting as they keep the ...
Psychopharmacology and Other Biologic Treatments
... blood brain barrier (then, can also pass through placenta) ...
... blood brain barrier (then, can also pass through placenta) ...
Legal Highs - Dual Diagnosis Leeds
... death with other sympathomimetics. Potentiated by MAOIs. Combined amphetamine and beta blockers may cause alpha adrenergic overactivity – hypertension. Interactions are rare. Psychosis may occur with disulfiram or SSRIs. Enzyme induction reduces plasma levels of theophylline and propranalol. Stimula ...
... death with other sympathomimetics. Potentiated by MAOIs. Combined amphetamine and beta blockers may cause alpha adrenergic overactivity – hypertension. Interactions are rare. Psychosis may occur with disulfiram or SSRIs. Enzyme induction reduces plasma levels of theophylline and propranalol. Stimula ...
Prescribing in the Elderly - Benton Franklin County Medical Society
... on weight in an attempt to conserve supplies Shortage of IV sulfamethoxazole/ trimethoprim) led to refractory cases of pneumocystis pneumonia from alternative treatment with clindamycin and primaquine ...
... on weight in an attempt to conserve supplies Shortage of IV sulfamethoxazole/ trimethoprim) led to refractory cases of pneumocystis pneumonia from alternative treatment with clindamycin and primaquine ...
FOOD-Drug Interactions (FDI)
... Role of pharmacist in preventing food-drug interaction Vigilant in monitoring for potential drug-food interactions Advising patients regarding foods or beverages to avoid when taking certain medications Pharmacists to keep upto-date on potential drug-food interactions of medications ...
... Role of pharmacist in preventing food-drug interaction Vigilant in monitoring for potential drug-food interactions Advising patients regarding foods or beverages to avoid when taking certain medications Pharmacists to keep upto-date on potential drug-food interactions of medications ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.