FUN2: 10:00-11:00 Scribe: Joan
... would give them thyroid hormone (or at least a drug that looks like it) so it’ll fit into the receptor and does what thyroid hormone would do. Hyperthyroidism can be combated by an antagonist. Its presence prevents thyroid hormone from binding to its receptor. You block the affect. It is a competiti ...
... would give them thyroid hormone (or at least a drug that looks like it) so it’ll fit into the receptor and does what thyroid hormone would do. Hyperthyroidism can be combated by an antagonist. Its presence prevents thyroid hormone from binding to its receptor. You block the affect. It is a competiti ...
drugs - Mount Psychology
... – 44% were occasional or frequent binge drinkers (5 in a row for men, 4 for women) – Male, white, aged 23 or younger, never married, and belonging to fraternities or sorority houses had higher binge drinking rates – Frequent bingers are more likely to miss a class, fall behind, forget where they wer ...
... – 44% were occasional or frequent binge drinkers (5 in a row for men, 4 for women) – Male, white, aged 23 or younger, never married, and belonging to fraternities or sorority houses had higher binge drinking rates – Frequent bingers are more likely to miss a class, fall behind, forget where they wer ...
Commonly used drugs - British Kidney Patient Association
... Bumetanide Furosemide Metolazone (very strong) Note: if given in too high dosage, these tablets can cause dehydration, low blood pressure and dizziness. Spironolactone can cause the potassium levels in the blood to rise. Drugs that control renal bone disease A) Phosphate binders Aluminium hydroxid ...
... Bumetanide Furosemide Metolazone (very strong) Note: if given in too high dosage, these tablets can cause dehydration, low blood pressure and dizziness. Spironolactone can cause the potassium levels in the blood to rise. Drugs that control renal bone disease A) Phosphate binders Aluminium hydroxid ...
Psychoactive Drugs
... • LSD – Produces hallucinations and delusions similar to a psychotic state – Can result in psychosis, memory loss, paranoia, panic attacks, nightmares and ...
... • LSD – Produces hallucinations and delusions similar to a psychotic state – Can result in psychosis, memory loss, paranoia, panic attacks, nightmares and ...
Evolution of toxic properties of Anti Alzheimer`s Drugs
... a thick layer that is capable of non-covalent interactions with the drug, similarly to that of receptor but with much looser steric requirements. High lipophilicity frequently leads to compounds with high rapid metabolic turnover 13 and low solubility and poor absorption. As lipophilicity (LogP) inc ...
... a thick layer that is capable of non-covalent interactions with the drug, similarly to that of receptor but with much looser steric requirements. High lipophilicity frequently leads to compounds with high rapid metabolic turnover 13 and low solubility and poor absorption. As lipophilicity (LogP) inc ...
Citalopram Hydrobromide - McGraw-Hill
... ● severe renal impairment, hepatic impairment, conditions likely to cause altered metabolism or hemodynamic responses ● history of mania or seizure disorder ● elderly patients ● pregnant patients ● children (safety not established). ...
... ● severe renal impairment, hepatic impairment, conditions likely to cause altered metabolism or hemodynamic responses ● history of mania or seizure disorder ● elderly patients ● pregnant patients ● children (safety not established). ...
Cardiovascular Drugs
... block potassium channels and prolong repolarization. They include sotalol, amiodarone, and bretylium Class IV: drugs block the slow calcium channel and include verapamil, diltiazem. ...
... block potassium channels and prolong repolarization. They include sotalol, amiodarone, and bretylium Class IV: drugs block the slow calcium channel and include verapamil, diltiazem. ...
Factors influencing drug effects in older adults
... How to improve pharmacotherapy in older adults? 1. Withdraw unnecessary drugs or reduce doses if appropriate 2. Determine whether „manifestations of the old age“ such as confusion, urination problems, dizzines, insomnia, etc are not due to drugs 3. In general, begin therapy with low doses 4. If pos ...
... How to improve pharmacotherapy in older adults? 1. Withdraw unnecessary drugs or reduce doses if appropriate 2. Determine whether „manifestations of the old age“ such as confusion, urination problems, dizzines, insomnia, etc are not due to drugs 3. In general, begin therapy with low doses 4. If pos ...
INCOMPATIBILITIES IN PRESCRIPTION Definition of Incompatibility
... particular disease or a particular patient who is allergic to it. ...
... particular disease or a particular patient who is allergic to it. ...
Chronotropic Effects of Select Cardiovascular Drugs on the
... embryonic vertebrate heart rate, and neither should be used in a clinical setting until proper dosage and deleterious effects are further analyzed. Data also strongly suggest that the affect of these drugs on the developing heart depends on the embryo’s stage of development and the strength and dos ...
... embryonic vertebrate heart rate, and neither should be used in a clinical setting until proper dosage and deleterious effects are further analyzed. Data also strongly suggest that the affect of these drugs on the developing heart depends on the embryo’s stage of development and the strength and dos ...
Drugedrug interaction through molecular structure similarity analysis
... Background Drugedrug interactions (DDIs) are responsible for many serious adverse events; their detection is crucial for patient safety but is very challenging. Currently, the US Food and Drug Administration and pharmaceutical companies are showing great interest in the development of improved tools ...
... Background Drugedrug interactions (DDIs) are responsible for many serious adverse events; their detection is crucial for patient safety but is very challenging. Currently, the US Food and Drug Administration and pharmaceutical companies are showing great interest in the development of improved tools ...
Ocular_Pharmacology_&_Toxicology_Dr._Kharashi
... It is the biological and therapeutic effect of the drug (mechanism of action) Most drugs act by binding to regulatory macromolecules, usually neurotransmitters or hormone receptors or enzymes If the drug is working at the receptor level, it can be agonist or antagonist If the drug is working ...
... It is the biological and therapeutic effect of the drug (mechanism of action) Most drugs act by binding to regulatory macromolecules, usually neurotransmitters or hormone receptors or enzymes If the drug is working at the receptor level, it can be agonist or antagonist If the drug is working ...
about drugs
... symptoms appear unless you take the drug. Addictive drugs also make you crave them - you have an overwhelming urge to continue taking the drug, even after withdrawal symptoms have disappeared. ...
... symptoms appear unless you take the drug. Addictive drugs also make you crave them - you have an overwhelming urge to continue taking the drug, even after withdrawal symptoms have disappeared. ...
Second-line anti
... times weekly during the continuation phase, under close monitoring for adverse effects. ...
... times weekly during the continuation phase, under close monitoring for adverse effects. ...
Drug Induced Liver Disease
... We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this materi ...
... We have reviewed this material in accordance with U.S. Copyright Law and have tried to maximize your ability to use, share, and adapt it. The citation key on the following slide provides information about how you may share and adapt this material. Copyright holders of content included in this materi ...
Exam-Objectives
... 23. 3 models of drug abuse and what treatment options follow from each. Include some variables that explain drug use in the behavioral model. 24. What are at least 2 ways of assaying the reinforcing value of a drug? 25. Siegel’s theory of morphine tolerance. Be able to diagram it to explain toleran ...
... 23. 3 models of drug abuse and what treatment options follow from each. Include some variables that explain drug use in the behavioral model. 24. What are at least 2 ways of assaying the reinforcing value of a drug? 25. Siegel’s theory of morphine tolerance. Be able to diagram it to explain toleran ...
Powerpoint of Dr. Savage`s presentation at
... have not identified because they are minors, were taken into protective custody, he said. As the teens were brought back to the station, Roarick said the police learned that the majority of them had taken multiple doses of Benadryl, an antihistamine, and that four had mixed it with Prozac, an antide ...
... have not identified because they are minors, were taken into protective custody, he said. As the teens were brought back to the station, Roarick said the police learned that the majority of them had taken multiple doses of Benadryl, an antihistamine, and that four had mixed it with Prozac, an antide ...
Grade 2008-2010 final exam-A
... 16. All of the following statements about cimetidine are true except A. An H2-receptor blocker B. used in peptic ulcer C. reduced the secretion of gastric acid D. little adverse reactions E. recurrence is rare after treatment is stopped 17. The patients with bronchial asthma can not be given A. adre ...
... 16. All of the following statements about cimetidine are true except A. An H2-receptor blocker B. used in peptic ulcer C. reduced the secretion of gastric acid D. little adverse reactions E. recurrence is rare after treatment is stopped 17. The patients with bronchial asthma can not be given A. adre ...
The Beginnings: Laboratory and Animal Studies: From Test Tube to
... lower cholesterol production. By the 1970s, scientists had found a possibility. They had isolated a chemical, mevalonic acid, which was an early link in the cholesterol chain, and an enzyme called HMG-CoA reductase, which produced mevalonic acid. What was needed, then, was a drug that could either i ...
... lower cholesterol production. By the 1970s, scientists had found a possibility. They had isolated a chemical, mevalonic acid, which was an early link in the cholesterol chain, and an enzyme called HMG-CoA reductase, which produced mevalonic acid. What was needed, then, was a drug that could either i ...
Basic Principles of Pharmacology
... pharmacokinetics and pharmacodynamics A Phase 0 study gives no data on safety or efficacy, being by definition a dose too low to cause any therapeutic effect. Drug development companies carry out Phase 0 studies to rank drug candidates in order to decide which has the best pharmacokinetic parameters ...
... pharmacokinetics and pharmacodynamics A Phase 0 study gives no data on safety or efficacy, being by definition a dose too low to cause any therapeutic effect. Drug development companies carry out Phase 0 studies to rank drug candidates in order to decide which has the best pharmacokinetic parameters ...
Drugs - PHARMACEUTICAL REVIEW
... A) Renal: Non-volatile drugs and metabolites are excreted in the urine. The clearance of some drugs depends mainly on renal excretion (Little or no metabolism) e.g. Atenolol, Nadolol, Barbitone & Gallamine Caution in Renal patients. Renal excretion is the result of glomerular ...
... A) Renal: Non-volatile drugs and metabolites are excreted in the urine. The clearance of some drugs depends mainly on renal excretion (Little or no metabolism) e.g. Atenolol, Nadolol, Barbitone & Gallamine Caution in Renal patients. Renal excretion is the result of glomerular ...
Chapt13 Lecture 13ed Pt 4
... skeletal muscles and tendons. • Automatic responses are called ________. ...
... skeletal muscles and tendons. • Automatic responses are called ________. ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.