FOM 2313 PHARMACOLOGY AND THERAPEUTICS
... Sympatholytic agents: Classification: receptor classification, selective and non selective. Special attributes to AADME and Effects and mechanism of action of @ group • Drugs affecting parasympathetic NS: Synthesis, storage, release of neurotransmitters and receptor systems of the PSNS. Location of ...
... Sympatholytic agents: Classification: receptor classification, selective and non selective. Special attributes to AADME and Effects and mechanism of action of @ group • Drugs affecting parasympathetic NS: Synthesis, storage, release of neurotransmitters and receptor systems of the PSNS. Location of ...
Document
... of therapy may be the cause; • Documentation showing why the resident's age, weight, or other factors would require a unique drug dose or drug duration, indication, or monitoring. ...
... of therapy may be the cause; • Documentation showing why the resident's age, weight, or other factors would require a unique drug dose or drug duration, indication, or monitoring. ...
Treatment Strategies for DWI Offenders
... 2010. Among people 25 to 64 years old, drug overdose caused more deaths than motor vehicle traffic crashes. ...
... 2010. Among people 25 to 64 years old, drug overdose caused more deaths than motor vehicle traffic crashes. ...
Routes of drug administration
... If any is swallowed that portion must be treated as an oral dose and subject to first pass metabolism. Only small doses can be accommodated easily. ...
... If any is swallowed that portion must be treated as an oral dose and subject to first pass metabolism. Only small doses can be accommodated easily. ...
PowerPoint 演示文稿
... drug does the body. That is original action between the drug and the cells of the body. The action of the drug does the body. That is original action between the drug and the cells of the body. ...
... drug does the body. That is original action between the drug and the cells of the body. The action of the drug does the body. That is original action between the drug and the cells of the body. ...
cholinergic agonists - Nursing Pharmacology
... arthritis, oral antidiabetic medications, thyroid replacement hormone, and a beta blocker for blood pressure. What potential adverse effect from the gingko would be of most concern for this patient? A. Stomach upset B. Diarrhea C. Bleeding D. Drowsiness ...
... arthritis, oral antidiabetic medications, thyroid replacement hormone, and a beta blocker for blood pressure. What potential adverse effect from the gingko would be of most concern for this patient? A. Stomach upset B. Diarrhea C. Bleeding D. Drowsiness ...
Frenxit Prescribing Information
... should not be given to patients who have received a MAO inhibitor within two weeks. Not recommended for excitable patient since its activating effect may lead to exaggeration of these characteristics. Precautions If previously the patient has been treated with tranquilizers with sedative effects the ...
... should not be given to patients who have received a MAO inhibitor within two weeks. Not recommended for excitable patient since its activating effect may lead to exaggeration of these characteristics. Precautions If previously the patient has been treated with tranquilizers with sedative effects the ...
Sustained Release Formulations
... release from the dosage form. Zero order release is a release which is independent of the amount of drug present in the dosage form. Usually SRDF’s do not follow zero order release but they try to mimic zero order release by releasing the drug in a slow first order fashion. Pharmacological action ...
... release from the dosage form. Zero order release is a release which is independent of the amount of drug present in the dosage form. Usually SRDF’s do not follow zero order release but they try to mimic zero order release by releasing the drug in a slow first order fashion. Pharmacological action ...
Previous Discussion Section Notes
... c. Monoamino-oxidase d. Presynaptic 2-receptors 13. Tranylcypromine and ephedrine both act through the adrenergic system, albeit through different mechanisms. Describe the differences between how these two drugs act. What side effects can occur from taking both of these drugs? a. Both indirect symp ...
... c. Monoamino-oxidase d. Presynaptic 2-receptors 13. Tranylcypromine and ephedrine both act through the adrenergic system, albeit through different mechanisms. Describe the differences between how these two drugs act. What side effects can occur from taking both of these drugs? a. Both indirect symp ...
No Slide Title
... • Studies carried out in healthy volunteers • Carried out by pharmaceutical companies or major hospitals • In some cases patients with the disease in question may be enrolled (cancer chemotherapy) • Initially small doses (as little as one fiftieth of intended dose) • Toxicity evaluated with routine ...
... • Studies carried out in healthy volunteers • Carried out by pharmaceutical companies or major hospitals • In some cases patients with the disease in question may be enrolled (cancer chemotherapy) • Initially small doses (as little as one fiftieth of intended dose) • Toxicity evaluated with routine ...
Kinetics and dynamics HW exercise
... Distribution: the drug is transported via the circulation to its site of action. Protein binding of drugs can prevent the movement of drugs from the blood to the tissue. Only unbound drug is available to have its effects on the body. The amount of albumin in the blood can modify the availability of ...
... Distribution: the drug is transported via the circulation to its site of action. Protein binding of drugs can prevent the movement of drugs from the blood to the tissue. Only unbound drug is available to have its effects on the body. The amount of albumin in the blood can modify the availability of ...
PowerPoint Template
... Storage conditions Proper container Anticipating interactions when mixing drugs and dosage forms ...
... Storage conditions Proper container Anticipating interactions when mixing drugs and dosage forms ...
The Role of Healthcare Professionals in ADR reporting
... and signifies a scientific way of thinking that requires certainty for action. However, it is unfortunate that this mind-set prevents some from reporting. After all, pharmacovigilance concerns the gathering of data on suspected ADRs. • It is the task of the national reporting centres to establish th ...
... and signifies a scientific way of thinking that requires certainty for action. However, it is unfortunate that this mind-set prevents some from reporting. After all, pharmacovigilance concerns the gathering of data on suspected ADRs. • It is the task of the national reporting centres to establish th ...
JCRC Radio Talk Show Outline
... ART drugs must be taken everyday at certain times each day. This is because the amount of drug in the body must remain at the same level all the time. ...
... ART drugs must be taken everyday at certain times each day. This is because the amount of drug in the body must remain at the same level all the time. ...
Drugs used in the Treatment of Alcohol Abuse/Addiction
... Due to its interaction with the enzyme dopamine-betahydroxylase , which breaks down doapmine, Antabuse adverse affects when combined with drugs affecting the release and re-uptake of dopamine (Such as Ritalin, Adderall, and Cocaine). Metabolism of other drugs may be inhibited by Antabuse (such a ...
... Due to its interaction with the enzyme dopamine-betahydroxylase , which breaks down doapmine, Antabuse adverse affects when combined with drugs affecting the release and re-uptake of dopamine (Such as Ritalin, Adderall, and Cocaine). Metabolism of other drugs may be inhibited by Antabuse (such a ...
Drug Interactions with Hormonal Contraception
... Healthcare professionals advising on and prescribing hormonal contraception should always ask women about their current and previous drug use including prescription, over the counter, herbal, recreational drugs and dietary supplements. Recent reports suggest widespread use of modafinil (an enzyme-in ...
... Healthcare professionals advising on and prescribing hormonal contraception should always ask women about their current and previous drug use including prescription, over the counter, herbal, recreational drugs and dietary supplements. Recent reports suggest widespread use of modafinil (an enzyme-in ...
New Antiepileptic Drugs
... – Very well tolerated – Minimal sedation – Probably safe in pregnancy – Approved for >2 y.o. – Monotherapy ...
... – Very well tolerated – Minimal sedation – Probably safe in pregnancy – Approved for >2 y.o. – Monotherapy ...
Drug Therapy in Pediatric Patients
... • Infants especially sensitive to drugs that affect CNS function • Dosage should also be reduced for drugs used for actions outside the CNS if those drugs are capable of producing CNS toxicity as a side effect – Endogenous compounds compete with drugs for available binding sites • Limited drug/prote ...
... • Infants especially sensitive to drugs that affect CNS function • Dosage should also be reduced for drugs used for actions outside the CNS if those drugs are capable of producing CNS toxicity as a side effect – Endogenous compounds compete with drugs for available binding sites • Limited drug/prote ...
Interpretation of Opiate Urine Drug Screens
... confirmation assay, i.e. below the cutoff. Similarly, the time between the last dose of a drug taken and the collection of the urine specimen may affect if the drug is present at concentrations adequate to produce a positive result. Metabolism - Metabolism is unique to each individual, determined by ...
... confirmation assay, i.e. below the cutoff. Similarly, the time between the last dose of a drug taken and the collection of the urine specimen may affect if the drug is present at concentrations adequate to produce a positive result. Metabolism - Metabolism is unique to each individual, determined by ...
Presentation - Faculty of pain medicine
... They denied suicidal attempt and explained they used amitriptyline in a dosage of 100 to 200 mg per day as a drug of abuse. On the day of admission one patient had increased the dosage to 600 mg which caused an acute intoxication. ...
... They denied suicidal attempt and explained they used amitriptyline in a dosage of 100 to 200 mg per day as a drug of abuse. On the day of admission one patient had increased the dosage to 600 mg which caused an acute intoxication. ...
Value of low dose combination treatment with blood pressure
... channel blockers were strongly dose related; symptoms caused by ACE inhibitors (mainly cough) were not dose related. Angiotensin II receptor antagonists caused no excess of symptoms. The prevalence of symptoms with two drugs in combination was less than additive. Adverse metabolic effects (such as c ...
... channel blockers were strongly dose related; symptoms caused by ACE inhibitors (mainly cough) were not dose related. Angiotensin II receptor antagonists caused no excess of symptoms. The prevalence of symptoms with two drugs in combination was less than additive. Adverse metabolic effects (such as c ...
MIOSHA Fact Sheet Preventing Exposure to Hazardous Drugs
... Are there standards to protect employees? Yes, the following MIOSHA standards apply. Part 92 and 430 Hazard Communication requires that employers maintain Safety Data Sheets (SDS) for hazardous drugs to which their employees are exposed. The drugs must be properly labeled according to the requiremen ...
... Are there standards to protect employees? Yes, the following MIOSHA standards apply. Part 92 and 430 Hazard Communication requires that employers maintain Safety Data Sheets (SDS) for hazardous drugs to which their employees are exposed. The drugs must be properly labeled according to the requiremen ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.