Centrally Acting Agents
... Methyldopa is incompletely absorbed after oral administration and undergoes extensive hepatic and pre-hepatic metabolism to form metabolites, some of which are active. The elimination halflife of the parent drug is about two hours. Moxonidine has pharmacokinetics very similar to those of clonidine b ...
... Methyldopa is incompletely absorbed after oral administration and undergoes extensive hepatic and pre-hepatic metabolism to form metabolites, some of which are active. The elimination halflife of the parent drug is about two hours. Moxonidine has pharmacokinetics very similar to those of clonidine b ...
Antipsychotic/Neuroleptic Agents and Lithium
... b. Stimulation of these receptors also can cause the depolarization of Glutamate neurons, by which may modulate behaviour of a human being ...
... b. Stimulation of these receptors also can cause the depolarization of Glutamate neurons, by which may modulate behaviour of a human being ...
Composition Each tablet contains: Sennosides 7.5 mg Properties
... Natural Laxative Senna is an anthraquinone laxative which is used to treat constipation & for bowel evacuation before radiological procedures. The active, anthraquinone is liberated into the colon from the glycosides by colonic bacteria & the effect usually occurs 6:12 hours after administration. Me ...
... Natural Laxative Senna is an anthraquinone laxative which is used to treat constipation & for bowel evacuation before radiological procedures. The active, anthraquinone is liberated into the colon from the glycosides by colonic bacteria & the effect usually occurs 6:12 hours after administration. Me ...
Psychotropic Drugs – Critical Thinking - KEY
... 2. Ecstasy or MDMA can be placed into either of two drug categories. Ecstasy increases heart rate and can cause muscle spasms, which is why it can be classified as a _____________ (stimulant) drug but the fact that it causes distorted perceptions makes this also a _____________ (hallucinogen) drug. ...
... 2. Ecstasy or MDMA can be placed into either of two drug categories. Ecstasy increases heart rate and can cause muscle spasms, which is why it can be classified as a _____________ (stimulant) drug but the fact that it causes distorted perceptions makes this also a _____________ (hallucinogen) drug. ...
Cytochrome P450
... Many drugs may increase or decrease the activity of various CYP isozymes in a phenomenon known as enzyme induction and inhibition. This is a major source of adverse drug interactions, since changes in CYP enzyme activity may affect the metabolism and clearance of various drugs. For example, if one d ...
... Many drugs may increase or decrease the activity of various CYP isozymes in a phenomenon known as enzyme induction and inhibition. This is a major source of adverse drug interactions, since changes in CYP enzyme activity may affect the metabolism and clearance of various drugs. For example, if one d ...
PatrickChapter2
... Strongest of the intermolecular bonds (20-40 kJ mol-1) Takes place between groups of opposite charge The strength of the ionic interaction is inversely proportional to the distance between the two charged groups Stronger interactions occur in hydrophobic environments The strength of interaction drop ...
... Strongest of the intermolecular bonds (20-40 kJ mol-1) Takes place between groups of opposite charge The strength of the ionic interaction is inversely proportional to the distance between the two charged groups Stronger interactions occur in hydrophobic environments The strength of interaction drop ...
pharm tech 2016-2017 class 2 ch 7 thru 13
... numbers of prescriptions or quantities O Large number of individuals dropping off prescriptions in someone else’s name O Large increases in controlled substance orders being ...
... numbers of prescriptions or quantities O Large number of individuals dropping off prescriptions in someone else’s name O Large increases in controlled substance orders being ...
1. (U4C3L1:Q1) Study the table and indicate t
... 36. (U4C3L1:G36) What is "Amotivational syndrome," and what drug causes it? A) A syndrome where one is obsessively driven to seek out drugs caused by all illegal drug use B) Apathy and loss of ambition and drive caused by amphetamine use C) Heightened ambition and drive for food caused by marijuana ...
... 36. (U4C3L1:G36) What is "Amotivational syndrome," and what drug causes it? A) A syndrome where one is obsessively driven to seek out drugs caused by all illegal drug use B) Apathy and loss of ambition and drive caused by amphetamine use C) Heightened ambition and drive for food caused by marijuana ...
Hallucinogens
... Note: Oral sedative dose 1-5 mg; subanesthetic dose 7.5 mg. Based on Petersen & Stillman, ...
... Note: Oral sedative dose 1-5 mg; subanesthetic dose 7.5 mg. Based on Petersen & Stillman, ...
Pharmacodynamics
... Strongest of the intermolecular bonds (20-40 kJ mol-1) Takes place between groups of opposite charge The strength of the ionic interaction is inversely proportional to the distance between the two charged groups Stronger interactions occur in hydrophobic environments The strength of interaction drop ...
... Strongest of the intermolecular bonds (20-40 kJ mol-1) Takes place between groups of opposite charge The strength of the ionic interaction is inversely proportional to the distance between the two charged groups Stronger interactions occur in hydrophobic environments The strength of interaction drop ...
Dr. Sitar's presentation
... one of which reduces pain. Some people can convert the inactive form to the active form Acetaminophen will not work well for pain caused by inflammation Caffeine will increase the efficacy of OTC drugs sold to treat pain Different drugs have different durations of action ti For persistent pain, drug ...
... one of which reduces pain. Some people can convert the inactive form to the active form Acetaminophen will not work well for pain caused by inflammation Caffeine will increase the efficacy of OTC drugs sold to treat pain Different drugs have different durations of action ti For persistent pain, drug ...
Downers: A New Look at Depressant Drugs
... It’s not just that downers are addictive—they’re all that and more. The worst part of a downer addiction is that they take away personal power and initiative and freedom, and never give it back. To get it back, you have to take it back. If you’re strung out on tranquilizers or other downer drugs, st ...
... It’s not just that downers are addictive—they’re all that and more. The worst part of a downer addiction is that they take away personal power and initiative and freedom, and never give it back. To get it back, you have to take it back. If you’re strung out on tranquilizers or other downer drugs, st ...
... No known interaction with Cytochrome P450 (CYP3A) No known interaction with disease to avoid toxic reactions Efficacy for all nasal symptoms including nasal obstruction Improvement of eye symptoms Improvement of asthma symptoms(short term studies) Reduction of asthma exacerbations(long t ...
PRESENTATION - FINAL - Critical Path to TB Drug Regimens
... with XDR-/TDR-TB at select centers with aim of cure – Potential collaborators: Tibotec, Otsuka, TB Alliance, Pfizer, Sequella – Once collaborators have committed, mouse relapse data of combination(s) to predict duration of treatment – By providing complete regimen, prevent emergence of resistance – ...
... with XDR-/TDR-TB at select centers with aim of cure – Potential collaborators: Tibotec, Otsuka, TB Alliance, Pfizer, Sequella – Once collaborators have committed, mouse relapse data of combination(s) to predict duration of treatment – By providing complete regimen, prevent emergence of resistance – ...
Pharmacology
... inhibit the action of an agonist, but initiate no effect themselves. Sometimes, the inhibition can be overcome by increasing the concentration of the agonist, ultimately achieving the same maximal effect. Examples of pure antagonists are atropine and curare, which inhibit the effects of acetylcholin ...
... inhibit the action of an agonist, but initiate no effect themselves. Sometimes, the inhibition can be overcome by increasing the concentration of the agonist, ultimately achieving the same maximal effect. Examples of pure antagonists are atropine and curare, which inhibit the effects of acetylcholin ...
SCHISTOSOMIASIS_F - King Saud University Medical Student
... • It is rapidly absorbed after oral administration • Carbohydrate diet and cimetidine increases its bioavailability • Corticosteroids and antiepileptics (phenytoin and carbamazepine) reduce its bioavailability. • Bioavailabilty is 80% ...
... • It is rapidly absorbed after oral administration • Carbohydrate diet and cimetidine increases its bioavailability • Corticosteroids and antiepileptics (phenytoin and carbamazepine) reduce its bioavailability. • Bioavailabilty is 80% ...
Common Drugs Cocaine - Cuyahoga County Medical Examiner
... substance for more than 100 years, and coca leaves, the source of cocaine, have been ingested for thousands of years. Pure cocaine was first extracted from the leaf of the Erythroxylon coca bush, which grows primarily in Peru and Bolivia, in the mid-19th century. In the early 1900s, it became the ma ...
... substance for more than 100 years, and coca leaves, the source of cocaine, have been ingested for thousands of years. Pure cocaine was first extracted from the leaf of the Erythroxylon coca bush, which grows primarily in Peru and Bolivia, in the mid-19th century. In the early 1900s, it became the ma ...
Antidepressant Drugs
... Phenelzine and isocarboxazide (no longer marketing), they bound irreversibly to MAO (A and B) with prolonged duration of action . Tranylcypromine which bound reversibly to MAO(A and B) with long duration of action. B-Selective inhibitors of MAO: -Selegiline is selective for MAO-B at low doses, but a ...
... Phenelzine and isocarboxazide (no longer marketing), they bound irreversibly to MAO (A and B) with prolonged duration of action . Tranylcypromine which bound reversibly to MAO(A and B) with long duration of action. B-Selective inhibitors of MAO: -Selegiline is selective for MAO-B at low doses, but a ...
ADMINISTRATION OF MEDICATIONS
... Have different responses to medications due to physiologic changes that accompany aging. Changes include decreased liver and kidney function, which can result in the accumulation of the drug in the ...
... Have different responses to medications due to physiologic changes that accompany aging. Changes include decreased liver and kidney function, which can result in the accumulation of the drug in the ...
AB_tox_07ho
... • most common with penicillins, cephalosporins • also seen with many others e.g. sulfonamides, tetracyclines, aminoglycosides ...
... • most common with penicillins, cephalosporins • also seen with many others e.g. sulfonamides, tetracyclines, aminoglycosides ...
Document
... Alters the activity of chemical messengers, which enable nerve cells in the brain to communicate with one another. It interferes with the body’s ability to control its temperature (severe medical consequences, death). Contains a number of other harmful drugs in it (caffeine, cough suppressants ...
... Alters the activity of chemical messengers, which enable nerve cells in the brain to communicate with one another. It interferes with the body’s ability to control its temperature (severe medical consequences, death). Contains a number of other harmful drugs in it (caffeine, cough suppressants ...
Ocular Pharmacology
... Travaprost, latanoprost, unoprostone, bimatoprost Prodrug is enzymatically hydrolyzed during its passage through the corneal epithelilum and the active form is released in the anterior chamber Cats have different receptors and are not able to metabolize these drugs like dogs or humans Increa ...
... Travaprost, latanoprost, unoprostone, bimatoprost Prodrug is enzymatically hydrolyzed during its passage through the corneal epithelilum and the active form is released in the anterior chamber Cats have different receptors and are not able to metabolize these drugs like dogs or humans Increa ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.