4.4 Special warnings and precautions for use
... analogues and bromocriptine may increase the availability of bromocriptine. ▪ Concomitant administration of bradycardia inducing drugs (e.g. beta blockers) may have an additive effect on the slight reduction of heart rate associated with lanreotide. Dose adjustments of such concomitant medications m ...
... analogues and bromocriptine may increase the availability of bromocriptine. ▪ Concomitant administration of bradycardia inducing drugs (e.g. beta blockers) may have an additive effect on the slight reduction of heart rate associated with lanreotide. Dose adjustments of such concomitant medications m ...
Course Syllabus
... C.1-Be able to distinguish one or two prototype drug(s) of each pharmacological group especially those of clinical importance. C.2-Acquire a comprehensive description of the major group of drugs as applied to medical practice and be sufficiently prepared to gather information on new drugs. C.3-Ident ...
... C.1-Be able to distinguish one or two prototype drug(s) of each pharmacological group especially those of clinical importance. C.2-Acquire a comprehensive description of the major group of drugs as applied to medical practice and be sufficiently prepared to gather information on new drugs. C.3-Ident ...
PowerPoint Sunusu
... Antagonists produce no effect by themselves. Competetive antagonists Non-competetive (irreversible) antagonists Competetive antagonists: both the antagonist and agonist bind to the ...
... Antagonists produce no effect by themselves. Competetive antagonists Non-competetive (irreversible) antagonists Competetive antagonists: both the antagonist and agonist bind to the ...
A Healthy Prognosis For Some Stocks: Drugs and Robots
... disease. There are some promising therapies being tested, including a sickle-cell anemia drug from bluebird bio [BLUE] and a hemophilia treatment from BioMarin Pharmaceutical [BMRN]. There are also a handful of public companies working on technology known as Crispr, which involves cutting away bad g ...
... disease. There are some promising therapies being tested, including a sickle-cell anemia drug from bluebird bio [BLUE] and a hemophilia treatment from BioMarin Pharmaceutical [BMRN]. There are also a handful of public companies working on technology known as Crispr, which involves cutting away bad g ...
Autonomic Nervous System
... decreased sympathetic outflow inhibiting cardioacceleration and vasoconstriction centers. Prevents pain signal transmission to the CNS by stimulating alpha-adrenergic receptors in the spinal cord. Therapeutic Effects: decreased blood ...
... decreased sympathetic outflow inhibiting cardioacceleration and vasoconstriction centers. Prevents pain signal transmission to the CNS by stimulating alpha-adrenergic receptors in the spinal cord. Therapeutic Effects: decreased blood ...
December 2016
... the deaths of Heath Ledger, Michael Jackson and Whitney Houston. One of the problems with these drugs is that the body quickly builds a tolerance to them, meaning that more of the drug must be taken to get the same effect, even after just a few weeks. This buildup of tolerance can occur again and ag ...
... the deaths of Heath Ledger, Michael Jackson and Whitney Houston. One of the problems with these drugs is that the body quickly builds a tolerance to them, meaning that more of the drug must be taken to get the same effect, even after just a few weeks. This buildup of tolerance can occur again and ag ...
Neurobiology of Drug Addiction - National Center for State Courts
... involved in the rewarding effects of drugs of abuse. Composed of central nucleus of the amygdala, bed nucleus of the stria terminalis, and a transition zone in the medial part of the nucleus accumbens Corticotropin-Releasing Factor — “brain stress” neurotransmitter, 41 amino acid polypeptide that co ...
... involved in the rewarding effects of drugs of abuse. Composed of central nucleus of the amygdala, bed nucleus of the stria terminalis, and a transition zone in the medial part of the nucleus accumbens Corticotropin-Releasing Factor — “brain stress” neurotransmitter, 41 amino acid polypeptide that co ...
Mechanisms of drug action
... β1 receptors are a sub group of adrenoceptors. Endogenous adrenaline and nor adrenaline act on these receptors in heart and increase heart rate and cardiac contractility there by increasing the cardiac work load and the blood pressure. Propranolol is a β receptor antagonist. It binds to β1 receptors ...
... β1 receptors are a sub group of adrenoceptors. Endogenous adrenaline and nor adrenaline act on these receptors in heart and increase heart rate and cardiac contractility there by increasing the cardiac work load and the blood pressure. Propranolol is a β receptor antagonist. It binds to β1 receptors ...
The Pharmacological Management of Hypertension
... If treatment is necessary, getting the pressure down is more important than worrying too much about which drug to use Thiazides are first choice for most people, CCB’s probably less so, doxazosin (α-blocker) first choice for almost no one! ...
... If treatment is necessary, getting the pressure down is more important than worrying too much about which drug to use Thiazides are first choice for most people, CCB’s probably less so, doxazosin (α-blocker) first choice for almost no one! ...
B. Drug-receptor interactions
... molecule and an electron acceptor in another. Electron donors such as alkenes, alkynes and aromatic ring bearing an electron donating group, and atoms having pairs of non-bonded electrons such as O, N and S Electron acceptors such as aromatic ring bearing an ...
... molecule and an electron acceptor in another. Electron donors such as alkenes, alkynes and aromatic ring bearing an electron donating group, and atoms having pairs of non-bonded electrons such as O, N and S Electron acceptors such as aromatic ring bearing an ...
An Efficient Reward System for Pharmaceutical Innovation
... • Vertex needs the revenues to support its on-going program of research into drugs for CF and other diseases. – This puts the normal way of funding research on its head. Firms don’t have a right to get a boatload of cash just because they are going to do research. They get paid money because they de ...
... • Vertex needs the revenues to support its on-going program of research into drugs for CF and other diseases. – This puts the normal way of funding research on its head. Firms don’t have a right to get a boatload of cash just because they are going to do research. They get paid money because they de ...
Fraud Control Issues After The Start of Medicare Part D
... Regional variations in programs Physicians, Pharmacies dealing with multiple contractors and data systems ...
... Regional variations in programs Physicians, Pharmacies dealing with multiple contractors and data systems ...
Document
... • Bronchiolar smooth muscle is relaxed by beta2 adrenergic receptor stimulation • Bronchiolar smooth muscle is contracted by cholinergic receptor stimulation • Respiratory secretions are increased by cholinergic stimulation • Drugs that increase intracellular levels of cyclic AMP produce bronchodila ...
... • Bronchiolar smooth muscle is relaxed by beta2 adrenergic receptor stimulation • Bronchiolar smooth muscle is contracted by cholinergic receptor stimulation • Respiratory secretions are increased by cholinergic stimulation • Drugs that increase intracellular levels of cyclic AMP produce bronchodila ...
Chapter 36 Drugs for Viral Infections HIV-AIDS
... – Administration of drugs via the Respiratory System provides a direct method of delivery for inhaled medications. The large surface area of the alveoli and bronchioles and extensive pulmonary capillary bed with its rich blood supply supports a localized, rapid onset of drug action. This local respo ...
... – Administration of drugs via the Respiratory System provides a direct method of delivery for inhaled medications. The large surface area of the alveoli and bronchioles and extensive pulmonary capillary bed with its rich blood supply supports a localized, rapid onset of drug action. This local respo ...
New antimicrobial drugs
... their outer layer; or even by pumping drugs out once they have entered. Resistant microbes, having a selective advantage over their non-resistant counterparts, will ...
... their outer layer; or even by pumping drugs out once they have entered. Resistant microbes, having a selective advantage over their non-resistant counterparts, will ...
Transdermal Delivery Systems
... 3. List the limitations on the types of drugs which can be administered by first-generation transdermal delivery systems. Explain why much of the drug is wasted, and how this is commercially feasible. 4. Draw the structures of the following drugs and circle the functionalities capable of ionization ...
... 3. List the limitations on the types of drugs which can be administered by first-generation transdermal delivery systems. Explain why much of the drug is wasted, and how this is commercially feasible. 4. Draw the structures of the following drugs and circle the functionalities capable of ionization ...
Link - thejabberwock
... antihypertensive to induce sleep. Over three years, each boy Rx 28 psychotropic drugs. New York Times, 2006 ...
... antihypertensive to induce sleep. Over three years, each boy Rx 28 psychotropic drugs. New York Times, 2006 ...
Hemispheric Drug Strategy - cicad
... that foster social inclusion and a reduction in those vulnerabilities. 3. Policies, measures and interventions to address the world drug problem should take gender issues into account. 4. Member states are responsible for providing the resources required for effective implementation of their nationa ...
... that foster social inclusion and a reduction in those vulnerabilities. 3. Policies, measures and interventions to address the world drug problem should take gender issues into account. 4. Member states are responsible for providing the resources required for effective implementation of their nationa ...
Chapter 21
... • Tissue distribution, metabolism and excretion – Drugs differ in how they are distributed, metabolized and excreted • Important factor for consideration when prescribing ...
... • Tissue distribution, metabolism and excretion – Drugs differ in how they are distributed, metabolized and excreted • Important factor for consideration when prescribing ...
Drugs by Design - Legal Highs? N.P.S overview
... softening or aroma therapeutic purposes. They are manufactured so as to include a central nervous stimulant used as a recreational drug, but in many cases the active chemical is slightly altered so it does avoids being classified as “illegal”. These substances are marketed as “bath salts”, “glass cl ...
... softening or aroma therapeutic purposes. They are manufactured so as to include a central nervous stimulant used as a recreational drug, but in many cases the active chemical is slightly altered so it does avoids being classified as “illegal”. These substances are marketed as “bath salts”, “glass cl ...
annotated bibliography - Michigan State University
... mouth, dilated pupils and various tingling sensations. Depression or moodiness may follow in the days following ecstasy use as well as general tiredness and hunger. Some women find that their periods become irregular or stop, while other have found that their periods become heavier and longer. Altho ...
... mouth, dilated pupils and various tingling sensations. Depression or moodiness may follow in the days following ecstasy use as well as general tiredness and hunger. Some women find that their periods become irregular or stop, while other have found that their periods become heavier and longer. Altho ...
pharma 16
... bacterial infection caused by Listeria monocytogens that goes inside the cell –intracellular- and cause very serious infection ,its food borne and grow on cold cut meat and vegetables .its very dangerous esp in pregnant ladies since it can be transmitted to the fetus , its lethal in that case that’ ...
... bacterial infection caused by Listeria monocytogens that goes inside the cell –intracellular- and cause very serious infection ,its food borne and grow on cold cut meat and vegetables .its very dangerous esp in pregnant ladies since it can be transmitted to the fetus , its lethal in that case that’ ...
HOW TO USE THIS BOOK
... • A retrospective study of 286 cases of isolated aripiprazole exposures found 55% of patients reported symptoms – somnolence (56%), sinus tachycardia (20%), nausea/vomiting (18%), dystonia (13%), tremor (6%), agitation, dizziness (2%), paresthesias, headache (1%). There were no reports of death, res ...
... • A retrospective study of 286 cases of isolated aripiprazole exposures found 55% of patients reported symptoms – somnolence (56%), sinus tachycardia (20%), nausea/vomiting (18%), dystonia (13%), tremor (6%), agitation, dizziness (2%), paresthesias, headache (1%). There were no reports of death, res ...
Basics Pharmacology Review Part 2 - Dr. Halil
... see: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694580/?tool=pubmed Accessed Apr 25/12. ...
... see: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2694580/?tool=pubmed Accessed Apr 25/12. ...
Drug interaction
A drug interaction is a situation in which a substance (usually another drug) affects the activity of a drug when both are administered together. This action can be synergistic (when the drug's effect is increased) or antagonistic (when the drug's effect is decreased) or a new effect can be produced that neither produces on its own. Typically, interactions between drugs come to mind (drug-drug interaction). However, interactions may also exist between drugs and foods (drug-food interactions), as well as drugs and medicinal plants or herbs (drug-plant interactions). People taking antidepressant drugs such as monoamine oxidase inhibitors should not take food containing tyramine as hypertensive crisis may occur (an example of a drug-food interaction). These interactions may occur out of accidental misuse or due to lack of knowledge about the active ingredients involved in the relevant substances.It is therefore easy to see the importance of these pharmacological interactions in the practice of medicine. If a patient is taking two drugs and one of them increases the effect of the other it is possible that an overdose may occur. The interaction of the two drugs may also increase the risk that side effects will occur. On the other hand, if the action of a drug is reduced it may cease to have any therapeutic use because of under dosage. Notwithstanding the above, on occasion these interactions may be sought in order to obtain an improved therapeutic effect. Examples of this include the use of codeine with paracetamol to increase its analgesic effect. Or the combination of clavulanic acid with amoxicillin in order to overcome bacterial resistance to the antibiotic. It should also be remembered that there are interactions that, from a theoretical standpoint, may occur but in clinical practice have no important repercussions.The pharmaceutical interactions that are of special interest to the practice of medicine are primarily those that have negative effects for an organism. The risk that a pharmacological interaction will appear increases as a function of the number of drugs administered to a patient at the same time.It is possible that an interaction will occur between a drug and another substance present in the organism (i.e. foods or alcohol). Or in certain specific situations a drug may even react with itself, such as occurs with dehydration. In other situations, the interaction does not involve any effect on the drug. In certain cases, the presence of a drug in an individual's blood may affect certain types of laboratory analysis (analytical interference).It is also possible for interactions to occur outside an organism before administration of the drugs has taken place. This can occur when two drugs are mixed, for example, in a saline solution prior to intravenous injection. Some classic examples of this type of interaction include that Thiopentone and Suxamethonium should not be placed in the same syringe and same is true for Benzylpenicillin and Heparin. These situations will all be discussed under the same heading due to their conceptual similarity.Drug interactions may be the result of various processes. These processes may include alterations in the pharmacokinetics of the drug, such as alterations in the absorption, distribution, metabolism, and excretion (ADME) of a drug. Alternatively, drug interactions may be the result of the pharmacodynamic properties of the drug, e.g. the co-administration of a receptor antagonist and an agonist for the same receptor.