The Art of Multiple Sequence Alignment in R
... metrics in order to accomplish a combination of both structural alignment and evolutionary alignment. The idea is to give the alignment a biological basis even though the molecules that the sequences represent will never meet each other and align under any natural circumstance. The workhorse for seq ...
... metrics in order to accomplish a combination of both structural alignment and evolutionary alignment. The idea is to give the alignment a biological basis even though the molecules that the sequences represent will never meet each other and align under any natural circumstance. The workhorse for seq ...
Transfer of genetic material between the chloroplast and nucleus
... nuclear genome data reported that the plant nuclear genome is in equilibrium between frequent integration and rapid elimination of the chloroplast genome and that the pericentromeric regions play a significant role in facilitating the chloroplast–nuclear DNA flux. This equilibrium between integratio ...
... nuclear genome data reported that the plant nuclear genome is in equilibrium between frequent integration and rapid elimination of the chloroplast genome and that the pericentromeric regions play a significant role in facilitating the chloroplast–nuclear DNA flux. This equilibrium between integratio ...
Regulation of DNA Polymerase Exonucleolytic Proofreading Activity
... proofreading, which removes correct nucleotides in addition to incorrect nucleotides (Muzyczka et al. 1972; Gillin and Nossal, 1976a; reviewed in Goodman et al. 1993). Another potential disadvantage of increased DNA replication accuracy is the possible necessity of a certain minimal mutation rate th ...
... proofreading, which removes correct nucleotides in addition to incorrect nucleotides (Muzyczka et al. 1972; Gillin and Nossal, 1976a; reviewed in Goodman et al. 1993). Another potential disadvantage of increased DNA replication accuracy is the possible necessity of a certain minimal mutation rate th ...
Intelligent Icons: Integrating Lite-Weight Data Mining
... The three files in the example are ASCII text files, each of which contains approximately 16,000 base pairs of mitochondrial DNA. Here we used string edit distance as suggested in [15] to measure the distance between file names, and Euclidean distance to measure the distance between the file icons ( ...
... The three files in the example are ASCII text files, each of which contains approximately 16,000 base pairs of mitochondrial DNA. Here we used string edit distance as suggested in [15] to measure the distance between file names, and Euclidean distance to measure the distance between the file icons ( ...
Open Access version via Utrecht University Repository
... comparison with BUS in cattle, humans, rabbits, horses, mice and rats. It appeared that BUS in dogs had unique features. However, is this still true when the AF3 domain and putative phosphorylation sites are compared with more species? This leads to the following hypothesis: the sequence of the AF3 ...
... comparison with BUS in cattle, humans, rabbits, horses, mice and rats. It appeared that BUS in dogs had unique features. However, is this still true when the AF3 domain and putative phosphorylation sites are compared with more species? This leads to the following hypothesis: the sequence of the AF3 ...
Nucleotide sequence analysis - Bioinformatics Unit
... •Is it contaminated with vector sequences? •Is it an already known gene? •Is it related to any other genes either by having a common ancestor? •Is it similar in function to other genes via convergent evolution? •What could the protein sequence be for this nucleotide fra ...
... •Is it contaminated with vector sequences? •Is it an already known gene? •Is it related to any other genes either by having a common ancestor? •Is it similar in function to other genes via convergent evolution? •What could the protein sequence be for this nucleotide fra ...
Explaining the Likelihood Ratio in DNA Mixture Interpretation
... The likelihood ratio (LR) appears in many fields of biological, information, physical and social science. The LR is a standard measure of information that summarizes in a single number the data support for a hypothesis. It is a way of accounting for all the evidence in favor of or against a particul ...
... The likelihood ratio (LR) appears in many fields of biological, information, physical and social science. The LR is a standard measure of information that summarizes in a single number the data support for a hypothesis. It is a way of accounting for all the evidence in favor of or against a particul ...
Cophylogeny and disparate rates of evolution in sympatric lineages
... the C. merriami species group of the Trans-Mexican Volcanic Belt and Oriental Basin (Fig. 1). The C. merriami species group is parasitized by two louse species complexes in the genus Geomydoecus, the G. coronadoi complex (consisting of two louse species, G. coronadoi and G. veracruzensis) and the G. ...
... the C. merriami species group of the Trans-Mexican Volcanic Belt and Oriental Basin (Fig. 1). The C. merriami species group is parasitized by two louse species complexes in the genus Geomydoecus, the G. coronadoi complex (consisting of two louse species, G. coronadoi and G. veracruzensis) and the G. ...
ISOLATE II PCR and Gel Kit
... PCR primers from reactions are eliminated while small DNA fragments are still bound and purified with high recovery. The cut-off for small DNA fragments can be shifted from <50bp to several hundred base pairs by diluting Binding Buffer CB to remove primer-dimers from target PCR products. A yellow pH ...
... PCR primers from reactions are eliminated while small DNA fragments are still bound and purified with high recovery. The cut-off for small DNA fragments can be shifted from <50bp to several hundred base pairs by diluting Binding Buffer CB to remove primer-dimers from target PCR products. A yellow pH ...
Developing expressed sequence tag libraries and
... Background: Due to a relatively high level of codominant inheritance and transferability within and among taxonomic groups, simple sequence repeat (SSR) markers are important elements in comparative mapping and delineation of genomic regions associated with traits of economic importance. Expressed s ...
... Background: Due to a relatively high level of codominant inheritance and transferability within and among taxonomic groups, simple sequence repeat (SSR) markers are important elements in comparative mapping and delineation of genomic regions associated with traits of economic importance. Expressed s ...
USB® Thermo Sequenase Cycle Sequencing Kit
... This kit and all enclosed reagents should be stored frozen at -20°C (NOT in a frostfree freezer). Keep all reagents on ice when removed from storage for use. The kit can conveniently be stored at +4°C for periods of up to 3 months with no loss of performance, but this should be avoided if it is expe ...
... This kit and all enclosed reagents should be stored frozen at -20°C (NOT in a frostfree freezer). Keep all reagents on ice when removed from storage for use. The kit can conveniently be stored at +4°C for periods of up to 3 months with no loss of performance, but this should be avoided if it is expe ...
Drug-specific Sites of Topoisomerase II DNA
... intensity patterns in sequencing gels (7—9). In past years, much attention has been focused on chromatin sites of topoisomerase II activity in living cells. This enzyme has been suggestedto regulate chromatin structure by specific interactions with SARs (1, 10—14)and scs regions (elements that d ...
... intensity patterns in sequencing gels (7—9). In past years, much attention has been focused on chromatin sites of topoisomerase II activity in living cells. This enzyme has been suggestedto regulate chromatin structure by specific interactions with SARs (1, 10—14)and scs regions (elements that d ...
Molecular Diagnostics for the Detection and Characterization of
... laboratories with limited personnel and still has a better time to result than traditional methods. It is now possible, with this technology, to provide a definitive species-level identification of microorganisms, such as S. aureus and C. albicans, on the same day that the blood culture bottle indic ...
... laboratories with limited personnel and still has a better time to result than traditional methods. It is now possible, with this technology, to provide a definitive species-level identification of microorganisms, such as S. aureus and C. albicans, on the same day that the blood culture bottle indic ...
Hybrid incompatibility is consistent with a hybrid origin of Heliconius
... H. cydno. Such crosses provide some evidence for genetic homology of pattern elements (Fig. 1; M. Linares, unpubl. data), as if similar phenotypes were independently derived in each species then one might expect some disruption of their development in hybrid individuals. Such breakdown does occur in ...
... H. cydno. Such crosses provide some evidence for genetic homology of pattern elements (Fig. 1; M. Linares, unpubl. data), as if similar phenotypes were independently derived in each species then one might expect some disruption of their development in hybrid individuals. Such breakdown does occur in ...
MacVector 14.0 Getting Started Guide
... Both multiple and pairwise alignments can be displayed in standard MacVector text tabs. Multiple alignments can be displayed as high quality PDF images that can be exported to other applications. A summary of the similarity scores between each pair of sequences can be displayed in tabular form. A co ...
... Both multiple and pairwise alignments can be displayed in standard MacVector text tabs. Multiple alignments can be displayed as high quality PDF images that can be exported to other applications. A summary of the similarity scores between each pair of sequences can be displayed in tabular form. A co ...
Candidatus Liberibacter asiaticus - Southwest Florida Research and
... one weak band for M. citri with a much larger size. Our previous study indicated there were more than 10 bacteria associated with citrus, including Bacillus spp., Microbacterium spp., Sphingomonas spp., Hymenobacter spp., Rhodococcus spp., and Pantoea agglomerans. None of the bacteria reacted with t ...
... one weak band for M. citri with a much larger size. Our previous study indicated there were more than 10 bacteria associated with citrus, including Bacillus spp., Microbacterium spp., Sphingomonas spp., Hymenobacter spp., Rhodococcus spp., and Pantoea agglomerans. None of the bacteria reacted with t ...
Intelligent Icons: Integrating Lite-Weight Data Mining
... We can use INTELLIGENT ICONS to solve this problem by arranging the icons in the file browser based on their similarity, rather than the classic options of name, size, date etc. There has been much work on arranging icons (glyphs/photo thumbnails etc) on a screen (see [22] for an excellent overview) ...
... We can use INTELLIGENT ICONS to solve this problem by arranging the icons in the file browser based on their similarity, rather than the classic options of name, size, date etc. There has been much work on arranging icons (glyphs/photo thumbnails etc) on a screen (see [22] for an excellent overview) ...
生物信息学主要英文术语及释义
... state of a hid-den Markov model (representing one column of a multiple sequence alignment of proteins), based on prior distributions found in conserved protein domains (blocks). Distance in sequence analysis(序列距离) The number of observed changes in an optimal alignment of two sequences, usually not c ...
... state of a hid-den Markov model (representing one column of a multiple sequence alignment of proteins), based on prior distributions found in conserved protein domains (blocks). Distance in sequence analysis(序列距离) The number of observed changes in an optimal alignment of two sequences, usually not c ...
Rapid and Quantitative Detection of Toxoplasma Gondii by PCR
... brew” applications for prenatal diagnosis of toxoplasmosis, in particular, making it faster, more sensitive, and decreases morbidity, because it is currently based on amniocentesis alone [4]. However, the main risk concerns false-positive results arising from contamination with previously amplified ...
... brew” applications for prenatal diagnosis of toxoplasmosis, in particular, making it faster, more sensitive, and decreases morbidity, because it is currently based on amniocentesis alone [4]. However, the main risk concerns false-positive results arising from contamination with previously amplified ...
K - Romanian Biotechnological Letters
... time interval and the ramping. Using a computer controlled device, only few parameters must be defined, every cycle consisting of a succession of steps (forward migration, pause, reverse migration, pause) being controlled by computer, according to the chosen ramp and parameters. It is obvious that, ...
... time interval and the ramping. Using a computer controlled device, only few parameters must be defined, every cycle consisting of a succession of steps (forward migration, pause, reverse migration, pause) being controlled by computer, according to the chosen ramp and parameters. It is obvious that, ...
Cleavage of a model DNA replication fork by a Type I restriction
... (REases) recognize a specific DNA sequence and cleave DNA when the sequence is not methylated by the cognate methyltransferase (16). They would cleave incoming or foreign DNA lacking proper methylation, but sometimes they attack their host bacterial chromosome, sensing its lack of methylation. For ex ...
... (REases) recognize a specific DNA sequence and cleave DNA when the sequence is not methylated by the cognate methyltransferase (16). They would cleave incoming or foreign DNA lacking proper methylation, but sometimes they attack their host bacterial chromosome, sensing its lack of methylation. For ex ...
Agarose Gel Electrophoresis
... turns remain (usually between 0.1 to 0.5 µg/ml). As still more ethidium bromide is bound, positive superhelical turns are generated which, like negative supercoils, cause an increase in the electrophoretic mobility of the molecules (i.e., Fig. 2.5A.2D). By running gels at different concentrations of ...
... turns remain (usually between 0.1 to 0.5 µg/ml). As still more ethidium bromide is bound, positive superhelical turns are generated which, like negative supercoils, cause an increase in the electrophoretic mobility of the molecules (i.e., Fig. 2.5A.2D). By running gels at different concentrations of ...