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Functional Photonics for Single Bioentities a biophotonics Platform
Functional Photonics for Single Bioentities a biophotonics Platform

... • Current DNA probe applications overcome this problem by employing polymerase chain reaction (PCR). – PCR amplifies target DNA molecules more than one million fold. Amplified PCR product can then be detected by conventional DNA probes. ...
Bacterial transformation
Bacterial transformation

... the presence of the antibiotic ampicillin. However, the bacteria that have taken up the plasmid (transformed) and express the ampicillin resistance gene product from the plasmid will be able to grow on media containing ampicillin while all the other bacteria will die; a powerful technique called sel ...
Data Acquisition Tools & Techniques
Data Acquisition Tools & Techniques

... includes extragenic material as well as genes. In eukaryotes, genomic DNA contains introns • cDNA is reverse-transcribed from mRNA and corresponds only to the expressed parts of the genome. It does not contain introns • Recombinant DNA comes from the laboratory and comprises artificial DNA molecules ...
ISTANBUL MEDIPOL UNIVERSITY Course Learning Outcomes of
ISTANBUL MEDIPOL UNIVERSITY Course Learning Outcomes of

... cell biology (metabolism and genetic), define nutrient and other physical needs of microorganisms, to teach basic laboratory techniques of working with microorganisms (culture techniques, Gram stain, Acid fast stain, spore stain) with practical sessions in laboratory. 1.Describe Scope and History of ...
Polyploid Genomics
Polyploid Genomics

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Lesson

... when they extend their tongue from their mouth. This ability to roll the tongue is due to a dominant allele (R). Those who have the two recessive alleles (rr) can only curve their tongue slightly. Hitchhiker's thumb: (See Fig. 3) People with two recessive alleles (tt) for hitchhiker's thumb can bend ...
Homologous Recombination (Introductory Concepts
Homologous Recombination (Introductory Concepts

... purposes). How can recombination occur in this case? Replication can produce two sister copies of the  chromosome,  but  exchange  between  them  cannot  generate  new  gene  combinations  as  the  two  chromosome  copies  are  identical  (unless  mistakes  in  replication  has  generated  mutation ...
Annotation Practice Activity [Based on materials from the GEP
Annotation Practice Activity [Based on materials from the GEP

Standard 1: The Cell—Cells are the fundamental unit
Standard 1: The Cell—Cells are the fundamental unit

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F215: Control, Genome and the Environment

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03-131 Genes, Drugs, and Disease Problem Set

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Topic Definition 3` Refers to the third carbon of the nucleic acid

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Exploring Nitrogen Fixing, Chemo heterotrophic Oligophiles from
Exploring Nitrogen Fixing, Chemo heterotrophic Oligophiles from

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... from the DNA, carries the message that will be translated to form a protein. – Ribosomal RNA (rRNA) forms part of ribosomes where proteins are made. – Transfer RNA (tRNA) brings amino acids from the cytoplasm to a ribosome. ...
Chapter 21: Genomics I: Analysis of DNA and Transposable Elements
Chapter 21: Genomics I: Analysis of DNA and Transposable Elements

... A sequence of DNA that is amplified by a single set of DNA primers. A genetic segment that is identical among all members of the population. ...
Recombinant DNA and Research with Animals
Recombinant DNA and Research with Animals

... ƒ The deliberate transfer of a drug resistance trait to microorganisms that are not known to acquire the trait naturally, if such acquisition could compromise the use of the drug to control disease agents in humans, veterinary medicine, or agriculture ...
Modern molecular biology techniques allow us to
Modern molecular biology techniques allow us to

Rapid DNA Extraction from Plant Seeds for PCR
Rapid DNA Extraction from Plant Seeds for PCR

... storage carbohydrates and polyphenols can interfere with successful amplification of DNA prepared from seeds. Until now, cumbersome preparation steps were needed to purify analytical amounts of seed DNA. EPICENTRE’s new QuickExtract™ Seed DNA Extraction Solution facilitates the extraction of PCR-rea ...
Epigenetics
Epigenetics

... Common pattern in many cancers  Loss of H4K16 acetylation and H4K20 tri-methylation When tumor suppressor genes are down-regulated by hypermethylation, oncogenes may be stimulated by acetylation or hypomethylation  Example: hypermethylation of H3K79 promotes leukemogenesis Tumor-specific epigeneti ...
Designer Babies and 21st Century Cures
Designer Babies and 21st Century Cures

... stem-cell science in order to find cures for the world’s most devastating genetic diseases and disorders, such as Parkinson’s and Hodgkin’s diseases. On a conceptual level, the process of cloning is really not very complicated. DNA is harvested from an adult cell (a mammary cell in the case of Dolly ...
ppt - eweb.furman.edu
ppt - eweb.furman.edu

Chapter 4: DNA, RNA, and the Flow of Genetic Information
Chapter 4: DNA, RNA, and the Flow of Genetic Information

... synthesized proteins to intracellular compartments and extracellular destinations. 6. Micro RNA (miRNA) is a class of small (about 21 nucleotides) noncoding RNAs that bind to complementary mRNA molecules and inhibit their translation. 7. Small interfering RNA (siRNA) is a class of small RNA molecule ...
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Molecular cloning



Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word cloning refers to the fact that the method involves the replication of one molecule to produce a population of cells with identical DNA molecules. Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine.In a conventional molecular cloning experiment, the DNA to be cloned is obtained from an organism of interest, then treated with enzymes in the test tube to generate smaller DNA fragments. Subsequently, these fragments are then combined with vector DNA to generate recombinant DNA molecules. The recombinant DNA is then introduced into a host organism (typically an easy-to-grow, benign, laboratory strain of E. coli bacteria). This will generate a population of organisms in which recombinant DNA molecules are replicated along with the host DNA. Because they contain foreign DNA fragments, these are transgenic or genetically modified microorganisms (GMO). This process takes advantage of the fact that a single bacterial cell can be induced to take up and replicate a single recombinant DNA molecule. This single cell can then be expanded exponentially to generate a large amount of bacteria, each of which contain copies of the original recombinant molecule. Thus, both the resulting bacterial population, and the recombinant DNA molecule, are commonly referred to as ""clones"". Strictly speaking, recombinant DNA refers to DNA molecules, while molecular cloning refers to the experimental methods used to assemble them.
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