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Microbes in Medicine and Research
Microbes in Medicine and Research

DNA polymerase
DNA polymerase

... When the process is complete, two DNA molecules have been formed identical to each other and to the parent molecule Errors during replication are rare, as each cell contains a family of more than thirty enzymes to ensure the accurate replication of DNA DNA polymerase makes very few errors, and most ...
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Chapter 20
Chapter 20

MCB Lecture 4 – Genes and Chromosomes
MCB Lecture 4 – Genes and Chromosomes

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File - sitdownandlogon

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MHP Lab 6 - Transformation and Transcription

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genetic_testD_key

... Determine the nucleotide sequence of the entire human genome Map the location of every gene on each chromosome in humans by the year 2003. HDP will only tell us the location of every gene not the function. ...
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Transformation (genetics)



In molecular biology, transformation is the genetic alteration of a cell resulting from the direct uptake and incorporation of exogenous genetic material (exogenous DNA) from its surroundings and taken up through the cell membrane(s). Transformation occurs naturally in some species of bacteria, but it can also be effected by artificial means in other cells. For transformation to happen, bacteria must be in a state of competence, which might occur as a time-limited response to environmental conditions such as starvation and cell density.Transformation is one of three processes by which exogenous genetic material may be introduced into a bacterial cell, the other two being conjugation (transfer of genetic material between two bacterial cells in direct contact) and transduction (injection of foreign DNA by a bacteriophage virus into the host bacterium).""Transformation"" may also be used to describe the insertion of new genetic material into nonbacterial cells, including animal and plant cells; however, because ""transformation"" has a special meaning in relation to animal cells, indicating progression to a cancerous state, the term should be avoided for animal cells when describing introduction of exogenous genetic material. Introduction of foreign DNA into eukaryotic cells is often called ""transfection"".
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