Predicting Adaptive Phenotypes From Multilocus Genotypes in Sitka
... regression-like models that take all single-nucleotide polymorphisms (SNPs) as predictor variables simultaneously. This approach is most frequently applied to mapping populations generated by controlled crosses for the purposes of selecting germplasm for deployment or further crosses in breeding pr ...
... regression-like models that take all single-nucleotide polymorphisms (SNPs) as predictor variables simultaneously. This approach is most frequently applied to mapping populations generated by controlled crosses for the purposes of selecting germplasm for deployment or further crosses in breeding pr ...
Molecular evolutionary analysis of the American pika
... Any particular evolutionary change within a population occurs with only certain probability (Nei 1987). A mutant allele caused by nucleotide substitution may spread through the population by genetic drift and/or natural selection (Hartl and Clark 1997). It is thus important to consider the relative ...
... Any particular evolutionary change within a population occurs with only certain probability (Nei 1987). A mutant allele caused by nucleotide substitution may spread through the population by genetic drift and/or natural selection (Hartl and Clark 1997). It is thus important to consider the relative ...
DNA METHODS FOR HLA TYPING A WORKBOOK FOR - ASHI-U
... Hematopoietic stem cells found in the bone marrow differentiate to become blood cells. These cells play important roles in fighting infection (white blood cells or lymphocytes), in transporting oxygen to the tissues (red blood cells), and in causing blood clotting (platelets). Certain types of cance ...
... Hematopoietic stem cells found in the bone marrow differentiate to become blood cells. These cells play important roles in fighting infection (white blood cells or lymphocytes), in transporting oxygen to the tissues (red blood cells), and in causing blood clotting (platelets). Certain types of cance ...
The enhancement of ribosomal transcription by the recycling of RNA
... (VI), and the deletion mutant, pXl^NSlc, (ANSI), as well as the positions of the deletion mutations in pXl^ESlc, (AES1) and pXl^ESXlc, (AESX1). Shading indicates sequence homologies and the known functional sequences, such as the spacer termination s i t e "T", the spacer promoters "SpPr I" and "SpP ...
... (VI), and the deletion mutant, pXl^NSlc, (ANSI), as well as the positions of the deletion mutations in pXl^ESlc, (AES1) and pXl^ESXlc, (AESX1). Shading indicates sequence homologies and the known functional sequences, such as the spacer termination s i t e "T", the spacer promoters "SpPr I" and "SpP ...
$doc.title
... § MAC review public comments & respond ▪ Discretion to involve CAC, extend comment period § MAC publish final rule within 45 days § LCD effective when published DV & Associates, Inc. ...
... § MAC review public comments & respond ▪ Discretion to involve CAC, extend comment period § MAC publish final rule within 45 days § LCD effective when published DV & Associates, Inc. ...
Gene interactions in the evolution of genomic imprinting
... alternative mechanisms (because it ensures that exactly one allelic copy will be expressed), and the theory of imprinting should not have the burden of explaining the existence of certain types of genetic variation. We therefore present this underdominant model as a simple but imperfect theory, and ...
... alternative mechanisms (because it ensures that exactly one allelic copy will be expressed), and the theory of imprinting should not have the burden of explaining the existence of certain types of genetic variation. We therefore present this underdominant model as a simple but imperfect theory, and ...
Shelef, Katie: A Critical Analysis of Degenerate Primer Design Programs
... reaction (PCR) has revolutionized the biological sciences. PCR can be used as a diagnostic tool in pathogen detection, genotyping, screening genes for mutations and identification of single nucleotide polymorphisms (SNPs), determining molecularly-defined evolutionary relationships among organisms, a ...
... reaction (PCR) has revolutionized the biological sciences. PCR can be used as a diagnostic tool in pathogen detection, genotyping, screening genes for mutations and identification of single nucleotide polymorphisms (SNPs), determining molecularly-defined evolutionary relationships among organisms, a ...
zChap07_140901 - Online Open Genetics
... is relatively rare). If meiosis results in recombination, the products are said to have a recombinant genotype. On the other hand, if no recombination occurs during meiosis, the products have their original combinations and are said to have a nonrecombinant, or parental genotype. Recombination is im ...
... is relatively rare). If meiosis results in recombination, the products are said to have a recombinant genotype. On the other hand, if no recombination occurs during meiosis, the products have their original combinations and are said to have a nonrecombinant, or parental genotype. Recombination is im ...
Document
... • Hybrids are phenotypically intermediate between parents • Most common outcome of hybridization due to the large number of genes typically involved in quantitative traits ...
... • Hybrids are phenotypically intermediate between parents • Most common outcome of hybridization due to the large number of genes typically involved in quantitative traits ...
The first page should show the paper title, names and addresses of
... differences in centromere positions, the gene order identified by FISH on CCO4 was the same as the gene order on GGA4 (Galkina et al. 2006). Thus, the high-resolution mapping did not confirm the pericentric inversion proposed earlier based on G-banding analysis and comparative FISH-mapping on metaph ...
... differences in centromere positions, the gene order identified by FISH on CCO4 was the same as the gene order on GGA4 (Galkina et al. 2006). Thus, the high-resolution mapping did not confirm the pericentric inversion proposed earlier based on G-banding analysis and comparative FISH-mapping on metaph ...
Pourcel et al., Microbiology 2005
... CRISPRs are present in both archaea and bacteria, in association with genes involved in DNA recombination and repair. In the Yersinia pestis genome, three such elements are found at three distinct loci, one of them being highly polymorphic. The authors have sequenced a total of 109 alleles of the th ...
... CRISPRs are present in both archaea and bacteria, in association with genes involved in DNA recombination and repair. In the Yersinia pestis genome, three such elements are found at three distinct loci, one of them being highly polymorphic. The authors have sequenced a total of 109 alleles of the th ...
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... cell division and proves lethal to foetus. We report a couple wherein wife had Recurrent Early Pregnancy Loss (REPL) due to loss of fetal cardiac activity and husband with oligoasthenospermia. The cytogenetic analysis of the wife showed 46,XX,9qh+ karyotype and that of husband revealed 47,XY,+mar ka ...
... cell division and proves lethal to foetus. We report a couple wherein wife had Recurrent Early Pregnancy Loss (REPL) due to loss of fetal cardiac activity and husband with oligoasthenospermia. The cytogenetic analysis of the wife showed 46,XX,9qh+ karyotype and that of husband revealed 47,XY,+mar ka ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... To determine whether inhibition of Merc gene expression affected development of non-mutant embryos, a sense or antisense oligodeoxynucleotide that spanned the predicted Merc translational initiation site was injected into fertilized 1-cell embryos obtained from superovulated FVB/N or C57BL/6J mice. ...
... To determine whether inhibition of Merc gene expression affected development of non-mutant embryos, a sense or antisense oligodeoxynucleotide that spanned the predicted Merc translational initiation site was injected into fertilized 1-cell embryos obtained from superovulated FVB/N or C57BL/6J mice. ...
TaqMan® Drug Metabolism Genotyping Assays
... using only this amount of product for the purchaser’s own internal research. Separate purchase of an Authorized 5' Nuclease Core Kit would convey rights under the applicable claims of US patents, and corresponding patent claims outside the United States, which claim 5’ nuclease methods. No right und ...
... using only this amount of product for the purchaser’s own internal research. Separate purchase of an Authorized 5' Nuclease Core Kit would convey rights under the applicable claims of US patents, and corresponding patent claims outside the United States, which claim 5’ nuclease methods. No right und ...
Divergent selection and heterogeneous genomic
... Levels of genetic differentiation between populations can be highly variable across the genome, with divergent selection contributing to such heterogeneous genomic divergence. For example, loci under divergent selection and those tightly physically linked to them may exhibit stronger differentiation ...
... Levels of genetic differentiation between populations can be highly variable across the genome, with divergent selection contributing to such heterogeneous genomic divergence. For example, loci under divergent selection and those tightly physically linked to them may exhibit stronger differentiation ...
A Road Map for HCV Genotyping
... 30% nucleotide identity within the envelope region and viruses within a clade vary by around 15%. • HCV genetic diversity is classified on three levels. – level 1 defines genotypes which differ by >35 % in nucleotide sequence over the whole 9.5kb genome (Genotype 1-7) – level 2 divides genotypes int ...
... 30% nucleotide identity within the envelope region and viruses within a clade vary by around 15%. • HCV genetic diversity is classified on three levels. – level 1 defines genotypes which differ by >35 % in nucleotide sequence over the whole 9.5kb genome (Genotype 1-7) – level 2 divides genotypes int ...
Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference
... added to the reference gene data set, we increment the value of NN, which is the relative position of the base in the reference gene sequence. Two separated reference gene sequences may contain the same bases, but their NN may be different, whereas P will be constant, allowing us to later determine ...
... added to the reference gene data set, we increment the value of NN, which is the relative position of the base in the reference gene sequence. Two separated reference gene sequences may contain the same bases, but their NN may be different, whereas P will be constant, allowing us to later determine ...
DIFFERENTIAL GENE RESPONSE TO MUTAGENS IN
... test if the paternal X has been affected by the treatment so as to carry: 1 ) an induced “visible” allelomorphic to the marker or 2) an induced “visible” as above together with a lethal somewhere else on the chromosome or 3 ) a deficiency or deletion (in itself a lethal) covering the locus of the ma ...
... test if the paternal X has been affected by the treatment so as to carry: 1 ) an induced “visible” allelomorphic to the marker or 2) an induced “visible” as above together with a lethal somewhere else on the chromosome or 3 ) a deficiency or deletion (in itself a lethal) covering the locus of the ma ...
chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
thymine dimers - Glen Research
... the preparation of proteins with variations at specific sites. This protein engineering technique uses oligonucleotides of mixed sequences to generate libraries of proteins for screening potential improvements in specific biological function. It is certainly possible to produce the mixed oligonucleo ...
... the preparation of proteins with variations at specific sites. This protein engineering technique uses oligonucleotides of mixed sequences to generate libraries of proteins for screening potential improvements in specific biological function. It is certainly possible to produce the mixed oligonucleo ...
Genetic diversity and epidemiology of infectious hematopoietic
... 6 or 7 d post-inoculation. Infected cells and media for each virus isolate were centrifuged and 1.0 m1 aliquots of supernatant were frozen at -7O0C. These served as the virus stock used in the study. The reference virus strain, RB1, isolated in 1975 from steelhead Oncorhynchus mykiss at the Round Bu ...
... 6 or 7 d post-inoculation. Infected cells and media for each virus isolate were centrifuged and 1.0 m1 aliquots of supernatant were frozen at -7O0C. These served as the virus stock used in the study. The reference virus strain, RB1, isolated in 1975 from steelhead Oncorhynchus mykiss at the Round Bu ...
Molecular Inversion Probe
Molecular Inversion Probe (MIP) belongs to the class of Capture by Circularization molecular techniques for performing genomic partitioning, a process through which one captures and enriches specific regions of the genome. Probes used in this technique are single stranded DNA molecules and, similar to other genomic partitioning techniques, contain sequences that are complementary to the target in the genome; these probes hybridize to and capture the genomic target. MIP stands unique from other genomic partitioning strategies in that MIP probes share the common design of two genomic target complementary segments separated by a linker region. With this design, when the probe hybridizes to the target, it undergoes an inversion in configuration (as suggested by the name of the technique) and circularizes. Specifically, the two target complementary regions at the 5’ and 3’ ends of the probe become adjacent to one another while the internal linker region forms a free hanging loop. The technology has been used extensively in the HapMap project for large-scale SNP genotyping as well as for studying gene copy alterationsand characteristics of specific genomic loci to identify biomarkers for different diseases such as cancer. Key strengths of the MIP technology include its high specificity to the target and its scalability for high-throughput, multiplexed analyses where tens of thousands of genomic loci are assayed simultaneously.