• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Color Atlas of Neurology
Color Atlas of Neurology

... Reflexes are involuntary and relatively stereotyped responses to specific stimuli. Afferent nerve fibers conduct the impulses generated by activated receptors to neurons in the central nervous system, which fire impulses that are then transmitted through efferent nerve fibers to the cells, muscles, ...
brain movement and disorder
brain movement and disorder

... Without this supraspinal innervation, such as after acute stroke, there is not enough background excitation of alpha motor neurons to sustain a reflex. Ultimately the 1A fibers sprout more synaptic knobs so alpha motor neurons are excited by stretch alone ...
A compensatory subpopulation of motor neurons in a mouse model
A compensatory subpopulation of motor neurons in a mouse model

... Amyotrophic lateral sclerosis is a fatal paralytic disease that targets motor neurons, leading to motor neuron death and widespread denervation atrophy of muscle. Previous electrophysiological data have shown that some motor axon branches attempt to compensate for loss of innervation, resulting in e ...
The Nervous System
The Nervous System

... • The cerebrum -- which is just Latin for "brain" -- is the newest (evolutionarily) and largest part of the brain as a whole. It is here that things like perception, imagination, thought, judgment, and decision occur. • The surface of the cerebrum -- the cerebral cortex -- is composed of six thin l ...
1. The diagram shows a cell organelle. (a) Identify the parts labelled
1. The diagram shows a cell organelle. (a) Identify the parts labelled

... she is able to see very little, but after a few minutes her vision improves, and continues to do so for 20 to 30 minutes. The graph shows the changes in the sensitivity of her retina over this period. ...
File
File

...  chemical messengers that traverse the synaptic gaps between neurons  when released by the sending neuron, neurotransmitters travel across the synapse and bind to receptor sites on the receiving neuron, thereby influencing whether it will generate a neural impulse ...
PDF here
PDF here

... The spinal cord was fixed in situ with 4% buffered paraformaldehyde for 48 h. The entire lumbar enlargement was then dissected, embedded in paraffin wax, and exhaustively cross-sectioned at 8 AM, six sections to a slide (123 F 12 slides or 5.90 F 0.58 mm of tissue per specimen). Tissue was deparaffi ...
Table 14.2 - (www.ramsey.k12.nj.us).
Table 14.2 - (www.ramsey.k12.nj.us).

... Motor axons innervate skeletal muscles • Neuromuscular junctions (motor end plates) Similar to synapses between neurons Acetylcholine diffuses across the synaptic cleft • Binds with molecules on the sarcolemma Motor axons branch to innervate muscle fibers Motor unit – a motor neuron and all the musc ...
Nervous System - Napa Valley College
Nervous System - Napa Valley College

... a great enough stimulation the channels won’t open. The level of the action potential is always the same.  The direction is always one way down the axon. The sodium channels are inactivated for awhile after the action potential passes = refractory period. ...
The Cerebral Cortex and Higher Intellectual
The Cerebral Cortex and Higher Intellectual

... Neuropathology of Parkinson’s disease • nigro-striatal pathway degeneration • leading to a depletion of striatal dopamine • some degeneration of other dopamine pathways too ...
vollllllkkks_1
vollllllkkks_1

... endings are derived from thin myelinated and unmyelinated C fibers and are unlike any other cutaneous area in the body.8 The nerve fibers from the receptors converge to form bundles of the dorsal nerve of the penis, which joins other nerves to become the pudendal nerve. Activation of these sensory r ...
this worksheet - (canvas.brown.edu).
this worksheet - (canvas.brown.edu).

Neuroscience 7b – Cortical Motor Function
Neuroscience 7b – Cortical Motor Function

... movement unless the stimuli is very intense (much more so than in M1). This are of the brain prepares M1 for the motor act. It does this by facilitating multiple columns in M1. These neurones are more easily stimulated by impulses from other parts of the brain and are close to the threshold level ne ...
NERVOUS SYSTEM1.ppt [Recovered]
NERVOUS SYSTEM1.ppt [Recovered]

... understand what was really taking place at the membrane of the neurons. The presence of ion channels needed to be studied experimentally and this technique provided the technology. Using a suction electrode (glass micropipette in top right) to suck onto a piece of membrane, which by gentle pulling b ...
document
document

... movement. Discharge continued until after the monkey had subsequently received a separate triggering signal (TS, which occurred at three different time intervals after the IS) and performed the movement. During the delay between IS and TS, while the monkey did not move, the discharge of the neuron e ...
Motor Systems II Loops and Tracts
Motor Systems II Loops and Tracts

... Two major cortical loops: • one through the basal ganglia and secondary motor cortex that selects and initiates action; • one through the cerebellum and primary motor cortex that modulates and sequences muscle contractions while a movement is in progress. Four major descending pathways (mainly from ...
Unit Four Essential Questions
Unit Four Essential Questions

The vertebrate nervous system is regionally specialized
The vertebrate nervous system is regionally specialized

... In an electrical synapse, electrical current flows directly from one cell to another via a gap junction. In a chemical synapse, depolarization of the synaptic terminal causes synaptic vesicles to fuse with the terminal membrane and to release neurotransmitter into the synaptic cleft. Direct synaptic ...
Ascending tracts
Ascending tracts

... lower motor neurons ( LMN ) motor neurons that innervate the voluntary muscles • in anterior gray column of spinal cord / • motor nuclei of brainstem – innervate skeletal muscles ...
Cerebellar system and diseases
Cerebellar system and diseases

... • It receives proprioceptive input from the spinocerebellar tract and from visual and auditory systems. • It sends fibres to deep cerebellar nuclei that, in turn, project to both the cerebral cortex and the brain stem, thus providing modulation of descending motor systems; POSTURE, MUSCLE TONE. ...
MS Word doc here
MS Word doc here

... in the Adelta range (15-30m/sec). Almost half of the unmyelinated axons of peripheral nerve respond well not only to intense mechanical stimuli, but also to heat and noxious chemicals. Axons of these polymodal nociceptors make up the majority of very slowly conducting (1m/s) C fibers in a peripheral ...
Chapt13 Lecture 13ed Pt 1
Chapt13 Lecture 13ed Pt 1

... anions inside the axon. Separation of charges polarizes the cell and causes the resting potential. ...
Lecture 2 Membrane Transport Membrane Transport Unassisted
Lecture 2 Membrane Transport Membrane Transport Unassisted

... and release of neurotransmitter Neurotransmitter diffuses across the synaptic cleft to the subsynaptic membrane and binds to specific receptors Binding triggers opening of ion channels ...
Motor System: Reflexes, Pyramidal Tract and Basal Ganglia
Motor System: Reflexes, Pyramidal Tract and Basal Ganglia

... in velocity and amplitude of movement): inappropriate activity in antagonist muscles ...
Sample Chapter
Sample Chapter

... Then, if it is a sufficiently strong stimulus, an action potential will occur. ...
< 1 ... 81 82 83 84 85 86 87 88 89 ... 209 >

Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report