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... D) the axon releases neurotransmitters that bind to and open potassium channels between the presynaptic and postsynaptic neurons. 35. What are the two types of classes that synapses can be categorized into? A) excitatory and inhibitory B) fast and slow C) complex and simple D) none of these types 36 ...
Lecture 3 Slides
Lecture 3 Slides

Chapter 12 The Nervous System
Chapter 12 The Nervous System

... of the Na+ channels open Na+ ions move into the axon, making the interior more positive than the outside of the neuron. This causes a depolarization in this area of the neuron, causing the polarity to be reversed area of the axon. The sodium rushes in displacing the potassium For a very short time ...
HISTAMINE AND RESTLESS LEGS SYNDROME
HISTAMINE AND RESTLESS LEGS SYNDROME

... and plays a role in wakefulness and in the transition between sleep and wakefulness; in the stomach it stimulates gastric secretion; and in the lungs, it plays a role in airway constriction. These varied functions result from the activation of four types of histamine receptors (labeled H1, H2, H3 an ...
sensory receptor
sensory receptor

...  This is called phantom limb sensation. ...
Sensory, Motor, and Integrative Systems
Sensory, Motor, and Integrative Systems

...  This is called phantom limb sensation. ...
Chapter 12
Chapter 12

... Chemical synapses (Signal transmitted across a gap by chemical neutrotransmitters) Are found in most synapses between neurons and all synapses between neurons and other cells Cells not in direct contact Action potential may or may not be propagated to postsynaptic cell, depending on Amount of neurot ...
Time constants
Time constants

... Typical membrane time constants, measured in this way or in similar ways, are about 15 ms for neocortical pyramidal cells and 20-50 ms for other CNS neurons (Koch et al. 1996, p. 96), which in our notation gives α = 70 s-1 for pyramidal cells and α = 20-50 s-1 for other neurons. The value for pyrami ...
Chapter Two - CogConfluence
Chapter Two - CogConfluence

... membrane or plasma membrane. It separates the extracellular (outside) environment from the cytosol, which is the intracellular (inside) fluid. It is semipermeable, meaning that some things are allowed through while others are not. Anions and cations are among the things that cannot pass a pure plasm ...
Circuits, Circuits
Circuits, Circuits

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Slide 1

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nervous systems
nervous systems

... Ions with opposite charges attract one another; ions with like charges repel. Ion pumps use energy to move ions or other molecules against their concentration gradients. The major ion pump in neuronal membranes is the sodium–potassium pump, which expels Na+ ions from the cell, exchanging them for K+ ...
Nervous System
Nervous System

... Saltatory Conduction • Ions pass through a myelinated axon only at the nodes of Ranvier creating an action potential – due to the large density of voltage-gated Na+ channels creates a large electrical field surrounding the node • causes the cell membrane to reach to threshold at a large distance aw ...
cranial nerve ix: glossopharyngeal nerve
cranial nerve ix: glossopharyngeal nerve

... 1. In this role, the Vagus is "stealing" some of the innervation from the Spinal Accessory (XI). Hence in this case the Vagus is actually innervating striated rather than smooth muscle. 2. VISCERAL MOTOR (GVE): Parasympathetics to the Thoracic and Abdominal viscera. 1. The Vagus serves no Parasympat ...
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... which the concentration and electrical gradients acting on that ion balance out. • The Nernst equation is a formula that converts energy stored in a concentration gradient to the energy stored as an electrical potential. This is calculated independently for each ion. ...
Physiology and Ecology Review
Physiology and Ecology Review

... Question 10: All of the following statements concerning characteristics of predator-prey relationships are correct EXCEPT: A. A rise in the population of prey is often followed by a rise in the population of predators. B. A rise in the population of predators is followed by a decrease in the popula ...
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Updating a Research Agenda for Cerebral Palsy Drs. Laura

... function. Volitional strength training, however, may not be optimal for producing strength gains in this population due to reduced voluntary muscle activation.  Neuromuscular electrical stimulation (NMES) activates a greater number of motor units and produces higher firing rates of the active motor ...
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Nervous System

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Sensory Nerves and Receptors

... Each receptor is highly sensitive to a certain type of stimulus which is called the "adequate stimulus" for this receptor (B) EXCITABILITY (THE GENERATOR OR THE RECEPTOR POTENTIAL) ...
Chapter 44 - Sensory Systems
Chapter 44 - Sensory Systems

The Spinal Nerves - White Plains Public Schools
The Spinal Nerves - White Plains Public Schools

... ANS Physiology NE is released by postganglionic sympathetic fibers at the synapses with their effectors. NE releasing fibers are called adrenergic fibers. ...
Understanding the Transmission of Nerve Impulses
Understanding the Transmission of Nerve Impulses

... outside of the cell contains excess sodium ions (Na+); the inside of the  cell contains excess potassium ions (K+). (Ions are atoms of an element  with a positive or negative charge.)  You're  probably  wondering:  How  can  the  charge  inside  the  cell  be  negative if the cell contains positive  ...
Human Physiology/The Nervous System
Human Physiology/The Nervous System

... (The downswing) is caused by the closing of sodium ion channels and the opening of potassium ion channels. Release of positively charged potassium ions (K+) from the nerve cell when potassium gates open. Again, these are opened in response to the positive voltage--they are voltage gated. This expuls ...
Module 4 - Neural and Hormonal Systems
Module 4 - Neural and Hormonal Systems

... recharge itself to fire again. ...
NERVOUS SYSTEMS – FUNCTION AT THE CELLULAR LEVEL
NERVOUS SYSTEMS – FUNCTION AT THE CELLULAR LEVEL

... A graded potential is any electrical change from resting potential - opening of gated channels due to binding of neurotransmitters: ion movement in or out of dendrites or cell body  change in membrane potential of cell body - amount of change varies (graded) depending on how many channels open and ...
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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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