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Motor “Binding:” Do Functional Assemblies in Primary Motor Cortex
Motor “Binding:” Do Functional Assemblies in Primary Motor Cortex

... The main finding from Jackson et al. is that CM cells with overlapping muscle fields exhibited greater neural synchronization than CM cells without overlapping muscle fields. Consistent with the finding between CM cellpair synchrony and overlapping muscle fields was a corollary finding of diminished ...
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Magnetic muscle stimulation produces fatigue without effort
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lmmunohistochemical Localization of Neuronal Nicotinic Receptors
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Chapter 13 - apsubiology.org
Chapter 13 - apsubiology.org

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Optical Control of Muscle Function by Transplantation of Stem Cell

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... PN could be afferent, sensory fibers enter the spinal cord via the dorsal roots, or efferent, motor fibers leave the spinal cord via the ventral roots. One nerve fiber consists of an axon and its nerve sheath. Each axon in the peripheral nervous system is surrounded by a sheath of Schwann cells. An ...
Build a neuron - Wake Forest University
Build a neuron - Wake Forest University

PDF file - University of Kentucky
PDF file - University of Kentucky

... (Houk and Henneman 1967; Houk and Simon, 1967). This is indicative the animals need to use this information for more than just protecting the muscle or tendons from the damage that could occur with extreme development of force. Perhaps the responses from tension reception aids in proprioception of t ...
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Neuromuscular junction



A neuromuscular junction (sometimes called a myoneural junction) is a junction between nerve and muscle; it is a chemical synapse formed by the contact between the presynaptic terminal of a motor neuron and the postsynaptic membrane of a muscle fiber. It is at the neuromuscular junction that a motor neuron is able to transmit a signal to the muscle fiber, causing muscle contraction.Muscles require innervation to function—and even just to maintain muscle tone, avoiding atrophy. Synaptic transmission at the neuromuscular junction begins when an action potential reaches the presynaptic terminal of a motor neuron, which activates voltage-dependent calcium channels to allow calcium ions to enter the neuron. Calcium ions bind to sensor proteins (synaptotagmin) on synaptic vesicles, triggering vesicle fusion with the cell membrane and subsequent neurotransmitter release from the motor neuron into the synaptic cleft. In vertebrates, motor neurons release acetylcholine (ACh), a small molecule neurotransmitter, which diffuses across the synaptic cleft and binds to nicotinic acetylcholine receptors (nAChRs) on the cell membrane of the muscle fiber, also known as the sarcolemma. nAChRs are ionotropic receptors, meaning they serve as ligand-gated ion channels. The binding of ACh to the receptor can depolarize the muscle fiber, causing a cascade that eventually results in muscle contraction.Neuromuscular junction diseases can be of genetic and autoimmune origin. Genetic disorders, such as Duchenne muscular dystrophy, can arise from mutated structural proteins that comprise the neuromuscular junction, whereas autoimmune diseases, such as myasthenia gravis, occur when antibodies are produced against nicotinic acetylcholine receptors on the sarcolemma.
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