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IOSR Journal of Electrical and Electronics Engineering (IOSR-JEEE) e-ISSN: 2278-1676,p-ISSN: 2320-3331,
IOSR Journal of Electrical and Electronics Engineering (IOSR-JEEE) e-ISSN: 2278-1676,p-ISSN: 2320-3331,

... From fig.4, it is observed that there is an appreciable amount of similarity still our plot is below the plot of the other model. Which signifies that the two models have the same sort of reasoning and logic but addition or removal of some parameter in the final flashover equation gives birth to a b ...
Formulation, Development and Characterization of Emulgel of
Formulation, Development and Characterization of Emulgel of

... Dissimilar formulations were formulated using altering amount of gelling agent and penetration enhancer. The method only differed in the process of making gel in diverse formulations. The formulation of emulsion was same in all the formulations. The gel bases were prepared by dispersing Carbopol 934 ...
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Therapeutic and systemic side effects of ocular beta

Modern Methods in Drug Discovery
Modern Methods in Drug Discovery

... schemes Leaving out one or more descriptors from the derived equation results in the crossvalidated correlation coefficient q2. This value is of course lower than the original r2. q2 being much lower than r2 indicates problems... ...
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Dissolution behavior of poly vinyl alcohol in water and its effect on

... 0.7 and 0.8 before flattening out at 0.9 and 1.0 % w/v respectively. ...
evaluation of the effect of lidocain induced local anaesthesia on
evaluation of the effect of lidocain induced local anaesthesia on

... Lidocain is the well-known local anaesthetic drug frequently used in simple dental treatment. Previous studies have shown that Lidocain is responsible for generation of free radicals and in turn contributing for increase in oxidative stress [1-3]. Meanwhile, simple dental treatment is often consider ...
Print - Arteriosclerosis, Thrombosis, and Vascular Biology
Print - Arteriosclerosis, Thrombosis, and Vascular Biology

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Vitamins, Supplements and Medication Safety

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patient informed consent for appetite suppressants

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Thorough QTc Studies: Patients at Heart...

... pharmacologic effect on cardiac repolarization, as detected by QT/QTc prolongation. The threshold level of regulatory concern is around 5ms as evidenced by an upper bound of the one-sided 95% confidence interval (CI) around the mean effect on baseline and placebo-corrected QTc of 10ms for at least o ...
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King Saud University College Of Pharmacy Department of Clinical Pharmacy

... Convenience for both patients and nurses. Likely on-time administration. A much reduced need for serum aminoglycoside levels (reduced cost). Facilitation of drug administration through home care services (reduce cost). Patients with CLcr < 40 mL/min, the aminoglycoside level may remain significantly ...
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P harmacokinetics in the newborn - TEDDY NoE e

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IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)

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Apr 2015 – Caffeine

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to get the file - Chair of Computational Biology

... • standard deviation (se) of 0.2–0.3 log units corresponds to a typical 2-fold error in experiments („soft data“). This gives rise to an upper limit of • r2 between 0.77–0.88 (for biological systems) → obtained correlations above 0.90 are highly likely to be accidental or due to overfitting (except ...
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PDF - International Journal of Pharma and Bio Sciences

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SYNTHESIS, DOCKING AND BIOLOGICAL STUDIES OF THE LINEAR TETRAPEPTIDE PWPV-A

... radical form, DPPH absorbs at 517 nm, but upon reduction by an antioxidant or a radical species its absorption decreases. Briefly, 1 mL of 0.1 M methanolic solution of DPPH was added to 3ml of the synthesized sample PWFV, at different concentrations in methanol (25, 50, 100µg/mL). The samples were k ...
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Accumulation of phytosterols in food. Evaluation of the adverse

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15 UPK 3_1_ - Asian Journal Of Advanced Basic Sciences

... Angiogenesis, the process that leads to the formation of new blood vessels or neovascularization, which is highly important during development but is largely not observed in the adult, except physiological exceptions in which angiogenesis occurs under tight regulation found in the female reproductiv ...
Systems of Linear Equations
Systems of Linear Equations

... Example 7 for y instead of z, the solution would have had a different form but would have led to the same set of solutions. In that case we would have z arbitrary, and the solution set would be of the form {(–2 + z, 3 – z, z)}. By choosing z = 2, one solution would be (0, 1, 2), which was found abov ...
Size: 841 kB 25th Aug 2014 Pharmacology Basics
Size: 841 kB 25th Aug 2014 Pharmacology Basics

... • Is the process by which a drug is eliminated from the body – by various organs such as the kidney and lungs and found in many biological fluids like: bile, sweat, hair, breast milk, or tears. However, the most common is the urine (excretion of drug) • In order to determine the rate of excretion o ...
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Plateau principle

The plateau principle is a mathematical model or scientific law originally developed to explain the time course of drug action The principle has wide applicability in pharmacology, physiology, nutrition, biochemistry and system dynamics. It applies whenever a drug or nutrient is infused or ingested at a relatively constant rate and when a constant fraction is eliminated during each time interval. Under these conditions, any change in the rate of infusion leads to an exponential increase or decrease until a new level is achieved. This behavior is also called an approach to steady state because rather than causing an indefinite increase or decrease, a natural balance is achieved when the rate of infusion or production is balanced by the rate of loss.An especially important use of the plateau principle is to study the renewal of tissue constituents in the human and animal body. In adults, daily synthesis of tissue constituents is nearly constant, and most constituents are removed with a first order reaction rate. Applicability of the plateau principle was recognized during radiotracer studies of protein turnover in the 1940s by Rudolph Schoenheimer and David Rittenberg. Unlike the case with drugs, the initial amount of tissue or tissue protein is not zero because daily synthesis offsets daily elimination. In this case, the model is also said to approach a steady state with exponential or logarithmic kinetics. Constituents that change in this manner are said to have a biological half-life.A practical application of the plateau principle is that most people have experienced ""plateauing"" during regimens for weight management or training for sports. After a few weeks of progress, one seems unable to continue gaining in ability or losing weight. This outcome results from the same underlying quantitative model. This entry will describe the popular concepts as well as development of the plateau principle as a scientific, mathematical model.In the sciences, the broadest application of the plateau principle is creating realistic time signatures for change in kinetic models (see Mathematical model). One example of this principle is the long time required to effectively change human body composition. Theoretical studies have shown that many months of consistent physical training and food restriction are needed to bring about permanent weight stability in people who were previously overweight.
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