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Unit 1: Cells - Loudoun County Public Schools
Unit 1: Cells - Loudoun County Public Schools

... 5. You should be able to define and utilize the following important terminology of genetics a) gene- section of DNA that carries a trait b) allele- as a form of a gene. c)dominant- a trait, that when present will be seen d) recessive- a trait that will only be seen when it is the only one present e ...
DNA Structure and Replication
DNA Structure and Replication

... • DNA molecule separates at its bases • Forms split, or replication fork • Each strand acts as a template ...
ICSB3: DRPM Measures
ICSB3: DRPM Measures

... 46*23*N * 6 * 67* 5 = > 2M combinations , 750 bp, >1E10 cells Roth DB et al Mol Cell Biol. 1989 9:3049 N (1-13): 14 22 13 15 10 4 5 4 2 2 3 2 1 ...
Sequencing a genome - Information Services and Technology
Sequencing a genome - Information Services and Technology

... Elements of a solution • Automation – over the past decade, the amount of hand-labor in the ‘reads’ has been steadily and dramatically reduced • Assembly of the reads into sequences is an algorithmic and computational problem ...
Genetics
Genetics

... Relate the concept of the gene to the sequences of nucleotides in DNA Sequence the steps involving protein synthesis Categorize the different kinds of mutations that can occur in DNA Compare the effects of different kinds of mutations on cells and organisms. ...
Lecture 6
Lecture 6

... • Statistical analysis of the rates of homologous recombination of several different genes could determine their order on a certain chromosome, and information from many such experiments could be combined to create a genetic map specifying the rough location of known genes relative to each other. • ...
Biology 102
Biology 102

... 7. ______________, guanine (G), cytosine (C), and thymine (T) are the 4 ______________________ in DNA. 8. In DNA, ____________________________ always forms hydrogen bonds with guanine (G). 9. The sequence of ____________________________ carries the genetic information of an organism. 10. Chargaff's ...
Comp 5c-2 Packet
Comp 5c-2 Packet

... Point mutations: Bases are ________  Harmful when:  Not harmful when: Correct DNA ...
homologous recombination
homologous recombination

... different alleles (both functional and non-functional ones), different genes or reporter genes (e.g. antibiotic resistance or green fluorescent protein). Regardless of what you want to insert, you must include some flanking DNA that is identical in sequence to the targeted locus ...
Bacterial genetics - Comenius University
Bacterial genetics - Comenius University

... - insertion sequences - genetic information for their own transfer - complex trasposons - genes for various kind of resistances, part of R plasmids resistance transfer factor - phage-associated transposons - ...
DNA Lecture #1: DNA Structure and Proof That DNA Controls Traits
DNA Lecture #1: DNA Structure and Proof That DNA Controls Traits

... attached to DNA entered the bacteria. The genetic material of viruses is DNA ...
GENETICS 603 Outline and Key Topics for Lecture 1 DNA
GENETICS 603 Outline and Key Topics for Lecture 1 DNA

... (They took advantage of radioisotopes to differentially label DNA and protein. ) 1956 Fraenkel-Conrat showed that the RNA present in TMV, not the protein coat, determined the type of progeny produced. The structure of DNA 1947 Chargaff showed that different species have different amounts of the4 nuc ...
Bacterial genetics
Bacterial genetics

... - insertion sequences - genetic information for their own transfer - complex trasposons - genes for various kind of resistances, part of R plasmids resistance transfer factor - phage-associated transposons - ...
Using DNA Subway in the Classroom Red Line Lesson
Using DNA Subway in the Classroom Red Line Lesson

... - It has to do with chromosomes (locus) - Its made from bases of DNA (composition) - It is a set of instructions or contains information (qualia) We should start answering more advanced questions about what composes a gene. ...
slides available - The National Academies of Sciences, Engineering
slides available - The National Academies of Sciences, Engineering

... • 1961-1968: The genetic triplet code and its translation into the amino acid sequence of proteins (the “Central Dogma”). Control of gene expression. • Since 1972: Recombinant DNA technology, mapping and sequencing of genes and genomes. Transgenesis. • 1984-2003: The Human Genome Project ...
George Church
George Church

... 3 paths to 10X error correction Tian et al. Nature. 432:1050 ...
Unit-1-Match-Up - Lesmahagow High School
Unit-1-Match-Up - Lesmahagow High School

... C. Sugar found in milk. D. This is when the shape of the active site ensures that multiple substrates are held together to allow a reaction to take place. E. Substance that binds to the repressor and prevents it from binding to the operator gene. F. Term used to describe that each enzyme only works ...
BioSc 231 Exam 5 2003
BioSc 231 Exam 5 2003

... _____ Differing sizes of restriction fragments produced from the alleles of a gene constitute A. a southern blot B. an allozyme C. identification of a gene D. a restriction fragment length polymorphism _____ Which of the following is NOT necessary in order for a population to maintain Hardy-Weinberg ...
M. K. Smith and J. K. Knight 3 SI Figure S2 Examples of formative
M. K. Smith and J. K. Knight 3 SI Figure S2 Examples of formative

... DNA sequence? A. nucleotides were deleted B. additional nucleotides were added C. one nucleotide was changed D. without additional information, any of the above are possible Homework question: Mutations in the adenomatous polyposis of the colon (APC) gene predisposes a person to colorectal cancer. B ...
Practicing Protein Synthesis
Practicing Protein Synthesis

... Below are two partial sequences of DNA bases. Sequence 1 is from a human and sequence 2 is from a cow. In both humans and cows, the sequence contains the gene to make the protein insulin. Insulin is necessary for the uptake of sugar from the blood. Without insulin, a person (or a cow) cannot digest ...
Deoxyribonucleic Acid (DNA)
Deoxyribonucleic Acid (DNA)

... Each DNA strand is made of combinations of four chemical units, called nucleotide bases, which comprise the genetic "alphabet." The bases are adenine (A), thymine (T), guanine (G), and cytosine (C). Bases on opposite strands pair specifically: A’s always pair with T’s, and C’s always pair with G’s. ...
Unit 7a * Structure of DNA
Unit 7a * Structure of DNA

... • He used two forms: the S form (deadly) and the R form (not deadly). • A transforming material passed from dead S bacteria to live R bacteria, making them deadly. • His results? Genetic material can transfer to other organisms ...
ZNF232: structure and expression analysis of a novel human C2H2
ZNF232: structure and expression analysis of a novel human C2H2

... cellular localization of the ZNF232 polypeptide and the functional role of the predicted NLS, we proceeded in transient expression of a green £uorescent proteinZNF232 chimera, in african green monkey COS-7 cells. The construct, pEGFP/ZNF232, contained the enhanced green £uorescent protein (GFP) open ...
Deoxyribonucleic Acid (DNA)
Deoxyribonucleic Acid (DNA)

... Each DNA strand is made of combinations of four chemical units, called nucleotide bases, which comprise the genetic "alphabet." The bases are adenine (A), thymine (T), guanine (G), and cytosine (C). Bases on opposite strands pair specifically: A’s always pair with T’s, and C’s always pair with G’s. ...
Name: Date: Chapter 3 Directed Reading (Section 1) Directions
Name: Date: Chapter 3 Directed Reading (Section 1) Directions

... 3.The subunits that make up DNA are called a. phosphates. c. amino acids. b. nucleotides. d. bases. 4. What two things must DNA be able to do? ...
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Zinc finger nuclease

Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes. By taking advantage of endogenous DNA repair machinery, these reagents can be used to precisely alter the genomes of higher organisms.
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