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PCR OrientaCon
PCR OrientaCon

... a. Imagine that the test tube was cooled to about 60°C, a temperature at which hydrogen bonds quickly re-form. Green, blue and black molecules can bind in two disKnct ways. Given that there are many, many short green and blue molecules: Which of these two bindings is more likely? ...
PDF
PDF

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Taster Lab Student Doc PDF
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Slide 1

... The entire human genome comprises over 3 billion base pairs. Here’s just the beginning. CGCAAATTTGCCGGATTTCCTTTGCTGTTCCTGCATGTAGTTTAAACGAGATTGCCA GCACCGGGTATCATTCACCATTTTTCTTTTCGTTAACTTGCCGTCAGCCTTTTCTTTGA CCTCTTCTTTCTGTTCATGTGTATTTGCTGTCTCTTAGCCCAGACTTCCCGTGTCCTTT CCACCGGGCCTTTGAGAGGTCACAGGGTCTTGA ...
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AP Biology
AP Biology

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M3 Multiplex Master Mix – PCR (2x)
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... MgCl2 concentrations are required, prepare a 25 mM MgCl2 stock solution (or request us to ship an aliquot along with your order) and add an appropriate amount to the reaction. Adding 1 μl of a 25 mM MgCl2 solution to a total reaction volume of 50 μl will add 25 nmol MgCl2 and thus increase total MgC ...
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Microsatellite



A microsatellite is a tract of repetitive DNA in which certain DNA motifs (ranging in length from 2–5 base pairs) are repeated, typically 5-50 times. Microsatellites occur at thousands of locations in the human genome and they are notable for their high mutation rate and high diversity in the population. Microsatellites and their longer cousins, the minisatellites, together are classified as VNTR (variable number of tandem repeats) DNA. The name ""satellite"" refers to the early observation that centrifugation of genomic DNA in a test tube separates a prominent layer of bulk DNA from accompanying ""satellite"" layers of repetitive DNA. Microsatellites are often referred to as short tandem repeats (STRs) by forensic geneticists, or as simple sequence repeats (SSRs) by plant geneticists.They are widely used for DNA profiling in kinship analysis and in forensic identification. They are also used in genetic linkage analysis/marker assisted selection to locate a gene or a mutation responsible for a given trait or disease.
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