Back_to_basics_pharmacology 1, 2, 3 and 4 Dr Riachi 2012
... Fluconazole is considered a moderate inhibitor of CYP3A4 and so less clinically important drug interactions. Strong CYP2C9, 2C19 inhibitor. QT prolongation with amiodarone, clarithromycin, TCA’s. Bioavailability of PO similar to IV; use PO if possible. ...
... Fluconazole is considered a moderate inhibitor of CYP3A4 and so less clinically important drug interactions. Strong CYP2C9, 2C19 inhibitor. QT prolongation with amiodarone, clarithromycin, TCA’s. Bioavailability of PO similar to IV; use PO if possible. ...
Pharmacology/Therapeutics I Block 2 Lectures 12. Drug Actions in
... mechanisms, (e.g., the action of monoamines: serotonin, norepinephrine and dopamine, are terminated by re-uptake into the pre-synaptic cell, while acetylcholine is degraded in the synaptic cleft). 2. Therapeutic examples: Targets of dopaminergic and adrenergic neurotransmission – dopaminergic, norad ...
... mechanisms, (e.g., the action of monoamines: serotonin, norepinephrine and dopamine, are terminated by re-uptake into the pre-synaptic cell, while acetylcholine is degraded in the synaptic cleft). 2. Therapeutic examples: Targets of dopaminergic and adrenergic neurotransmission – dopaminergic, norad ...
cHAPTER 7 The specificity of different selective and non
... mediation of pathologic anxiety states [2-5]. Benzodiazepines, which bind to the benzodiazepine gaba receptor, are highly effective therapeutic agents for the treatment of anxiety [1]. The introduction of the benzodiazepines in the 1960s was considered a significant improvement in the treatment of an ...
... mediation of pathologic anxiety states [2-5]. Benzodiazepines, which bind to the benzodiazepine gaba receptor, are highly effective therapeutic agents for the treatment of anxiety [1]. The introduction of the benzodiazepines in the 1960s was considered a significant improvement in the treatment of an ...
direct-to-consumer advertising
... This study determines how often and to what degree “imprecise frequency descriptors” are used in direct-to-consumer prescription drug advertisements that appear in consumer magazines targeted at readers over age 65. Much attention has been paid in recent years to the graying of America. Jewler and D ...
... This study determines how often and to what degree “imprecise frequency descriptors” are used in direct-to-consumer prescription drug advertisements that appear in consumer magazines targeted at readers over age 65. Much attention has been paid in recent years to the graying of America. Jewler and D ...
Altered Behavioral Response to Dopamine D3 Receptor Agonists 7
... Behavioral sensitization, the progressive and enduring enhancement of certain behaviors following repetitive drug use, is mediated in part by dopaminergic pathways. Increased locomotor response to drug treatment, a sensitizable behavior, is modulated by an opposing balance of dopamine receptor subty ...
... Behavioral sensitization, the progressive and enduring enhancement of certain behaviors following repetitive drug use, is mediated in part by dopaminergic pathways. Increased locomotor response to drug treatment, a sensitizable behavior, is modulated by an opposing balance of dopamine receptor subty ...
Afghanistan Synthetic Drugs Situation Assessment
... purity and, in addition to methamphetamine, may contain a variety of other substances. Crystalline methamphetamine is usually of a much higher purity than the tablet form. Presently, methamphetamine might be sold under various street names in Afghanistan (see Table 1, Chapter 1). New psychoactive s ...
... purity and, in addition to methamphetamine, may contain a variety of other substances. Crystalline methamphetamine is usually of a much higher purity than the tablet form. Presently, methamphetamine might be sold under various street names in Afghanistan (see Table 1, Chapter 1). New psychoactive s ...
Oral Drug Therapy Guidelines in Surgical Patients
... A patient may be ‘Nil-by-mouth’ for several reasons, e.g. non-functional gut, lack of swallowing reflex, patient unconscious or prior to surgery. Nausea or vomiting may also inhibit the use of oral medicines. Surgery is not an indication to stop the majority of medications a patient may be taking on ...
... A patient may be ‘Nil-by-mouth’ for several reasons, e.g. non-functional gut, lack of swallowing reflex, patient unconscious or prior to surgery. Nausea or vomiting may also inhibit the use of oral medicines. Surgery is not an indication to stop the majority of medications a patient may be taking on ...
Morphine Sulphate MOR Drugs
... known before morphine is administered. Morphine, when given IV takes a minimum of 2-3 minutes to begin to work, with the peak effect not being achieved for 10-20 minutes. Due to the variable absorption rate of morphine when given IM, particularly in the cardiac and trauma patient, this route should ...
... known before morphine is administered. Morphine, when given IV takes a minimum of 2-3 minutes to begin to work, with the peak effect not being achieved for 10-20 minutes. Due to the variable absorption rate of morphine when given IM, particularly in the cardiac and trauma patient, this route should ...
Read the updated advice - Association of Paediatric Anaesthetists
... Opioids may be required for second line analgesia in cases where the combination of paracetamol and a NSAID are inadequate. This can represent a problem in that dosing after discharge may not be foll ...
... Opioids may be required for second line analgesia in cases where the combination of paracetamol and a NSAID are inadequate. This can represent a problem in that dosing after discharge may not be foll ...
Potentially Harmful Drugs in the Elderly: Beers List
... certain populations.1 New to the 2015 version is a list of potentially harmful drug-drug interactions in seniors, as well as a list of medications that may need to be avoided or their dosage reduced based on renal function.1 This information is not comprehensive; medications and interactions were ch ...
... certain populations.1 New to the 2015 version is a list of potentially harmful drug-drug interactions in seniors, as well as a list of medications that may need to be avoided or their dosage reduced based on renal function.1 This information is not comprehensive; medications and interactions were ch ...
ANTI-INFLAMMATORY EFFECT OF THE SERRATIOPEPTIDASE
... to marketing of the drugs which are not approved. It even serves notices to online marketing websites (17). It is requirement of US FDA to do at least one placebo controlled clinical study to get approval for the marketing. However in India such norms are rarely followed. Its lack of mention of this ...
... to marketing of the drugs which are not approved. It even serves notices to online marketing websites (17). It is requirement of US FDA to do at least one placebo controlled clinical study to get approval for the marketing. However in India such norms are rarely followed. Its lack of mention of this ...
Posters - PsychoGenics
... Male Long-Evans rats (275-300g) were obtained from Harlan Laboratories (Indianapolis, IN). Upon arrival, the rats were assigned unique identification numbers (tail marked). Rats were single-housed in standard or OptiRAT cages and acclimated for 7 days prior to commencing a food-restriction regimen: ...
... Male Long-Evans rats (275-300g) were obtained from Harlan Laboratories (Indianapolis, IN). Upon arrival, the rats were assigned unique identification numbers (tail marked). Rats were single-housed in standard or OptiRAT cages and acclimated for 7 days prior to commencing a food-restriction regimen: ...
How predictive is ocular toxicology?
... layer; GCL ganglion cell layer; NFL neural (optic) fiber layer; and ILM inner limiting membrane. RPE retinal pigmented epithelium B) Optical coherence tomography (OCT) image of the same eye. Retinal layers are visualized as alternating light and dark bands, based on differential light reflectivity f ...
... layer; GCL ganglion cell layer; NFL neural (optic) fiber layer; and ILM inner limiting membrane. RPE retinal pigmented epithelium B) Optical coherence tomography (OCT) image of the same eye. Retinal layers are visualized as alternating light and dark bands, based on differential light reflectivity f ...
Tasers - Paramedic Systems of Wisconsin
... therapeutic drugs Treat for hyperthermia, dehydration, metabolic acidosis and potential ...
... therapeutic drugs Treat for hyperthermia, dehydration, metabolic acidosis and potential ...
Hyperlipidemias
... enterohepatic circulation. This causes hepatocytes to increase conversion of cholesterol to bile acids, resulting in decreasing the intracellular cholesterol concentration which activates an increased hepatic uptake of cholesterolcontaining LDL particles ( by increasing surface LDL receptors), leadi ...
... enterohepatic circulation. This causes hepatocytes to increase conversion of cholesterol to bile acids, resulting in decreasing the intracellular cholesterol concentration which activates an increased hepatic uptake of cholesterolcontaining LDL particles ( by increasing surface LDL receptors), leadi ...
Document name: ANTIDEPRESSANTS FOR THE TREATMENT OF
... ulcers. The risk of gastric bleeding is increased when aspirin, clopidogrel or NSAIDS are co-prescribed. The elderly and those with a previous history of bleeding are at greatest risk. Gastroprotective drugs such as omeprazole or lansoprazole should be considered in patients taking SSRIs with risk f ...
... ulcers. The risk of gastric bleeding is increased when aspirin, clopidogrel or NSAIDS are co-prescribed. The elderly and those with a previous history of bleeding are at greatest risk. Gastroprotective drugs such as omeprazole or lansoprazole should be considered in patients taking SSRIs with risk f ...
Chapter 4
... Metabolic Tolerance – Increase of alcohol digesting enzyme by the liver Behavioral Tolerance – Brain adapts to amount of drug present. A tolerant person can have a BAC 2x the amount of a nontolerant and act the same Environmental – the same environment over time when drinking increases tolerance. Ch ...
... Metabolic Tolerance – Increase of alcohol digesting enzyme by the liver Behavioral Tolerance – Brain adapts to amount of drug present. A tolerant person can have a BAC 2x the amount of a nontolerant and act the same Environmental – the same environment over time when drinking increases tolerance. Ch ...
Document
... Research indicates that the skills individuals learn through cognitive-behavioral approaches remain after the completion of treatment. In several studies, most people receiving a cognitivebehavioral approach maintained the gains they made in treatment throughout the following year. ((NIDA, 2012) ...
... Research indicates that the skills individuals learn through cognitive-behavioral approaches remain after the completion of treatment. In several studies, most people receiving a cognitivebehavioral approach maintained the gains they made in treatment throughout the following year. ((NIDA, 2012) ...
Prenatal Substance Abuse: Short- and Long
... the developing fetus, directly and indirectly.90 Cocaine’s teratogenic effects most likely result from interference with the neurotrophic roles of monoaminergic transmitters during brain development,91–94 which can significantly affect cortical neuronal development and may lead to morphologic abnorma ...
... the developing fetus, directly and indirectly.90 Cocaine’s teratogenic effects most likely result from interference with the neurotrophic roles of monoaminergic transmitters during brain development,91–94 which can significantly affect cortical neuronal development and may lead to morphologic abnorma ...
Prenatal Substance Abuse
... the developing fetus, directly and indirectly.90 Cocaine’s teratogenic effects most likely result from interference with the neurotrophic roles of monoaminergic transmitters during brain development,91–94 which can significantly affect cortical neuronal development and may lead to morphologic abnorma ...
... the developing fetus, directly and indirectly.90 Cocaine’s teratogenic effects most likely result from interference with the neurotrophic roles of monoaminergic transmitters during brain development,91–94 which can significantly affect cortical neuronal development and may lead to morphologic abnorma ...
Can`t I Just Take a Pill For It?
... airway muscles and reduces apneas. In June 2003 at the 2003 Associated Professional Sleep Societies (APSS) Conference in Chicago*, Carley and Radulovacki reported results of their study on 12 human subjects who had used mirtazapine to reduce sleep apnea. The subjects were given either a placebo or o ...
... airway muscles and reduces apneas. In June 2003 at the 2003 Associated Professional Sleep Societies (APSS) Conference in Chicago*, Carley and Radulovacki reported results of their study on 12 human subjects who had used mirtazapine to reduce sleep apnea. The subjects were given either a placebo or o ...
Cathinone derivatives: A review of their chemistry, pharmacology
... widespread phenomenon later in the decade.[17] Mephedrone (4methylmethcathinone) became commonplace via these outlets in 2007 and 2008. It seems that mephedrone originally became available in Israel, but its production ceased in 2008 when the Israeli government banned it. This was followed by an unp ...
... widespread phenomenon later in the decade.[17] Mephedrone (4methylmethcathinone) became commonplace via these outlets in 2007 and 2008. It seems that mephedrone originally became available in Israel, but its production ceased in 2008 when the Israeli government banned it. This was followed by an unp ...
Print this article - Hospital Chronicles
... dose-response values referenced for the Dopamine data were obtained from the Elkayam et al 2008 study in 13 patients with a history of congestive heart failure (CHF).19 In these patients, CHF was due to left ventricular systolic dysfunction with moderate to severe symptoms (New York Heart Associatio ...
... dose-response values referenced for the Dopamine data were obtained from the Elkayam et al 2008 study in 13 patients with a history of congestive heart failure (CHF).19 In these patients, CHF was due to left ventricular systolic dysfunction with moderate to severe symptoms (New York Heart Associatio ...
INTRODUCTION (586 words)
... depict the dose-effect relationship, shows an apparent ascending and descending limb. The same data are plotted in terms of dose versus intake (Figure 1B) in order to demonstrate that a relatively constant level of cocaine is maintained at the upper-end of the dose range. Although the log-log coordi ...
... depict the dose-effect relationship, shows an apparent ascending and descending limb. The same data are plotted in terms of dose versus intake (Figure 1B) in order to demonstrate that a relatively constant level of cocaine is maintained at the upper-end of the dose range. Although the log-log coordi ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.