Research Report Series
... What are the medical complications of chronic heroin use? No matter how they ingest the drug, chronic heroin users experience a variety of medical complications including insomnia and constipation. Lung complications (including various types of pneumonia and tuberculosis) may result from the poor h ...
... What are the medical complications of chronic heroin use? No matter how they ingest the drug, chronic heroin users experience a variety of medical complications including insomnia and constipation. Lung complications (including various types of pneumonia and tuberculosis) may result from the poor h ...
Section II. Autonomic Drugs Chapter 6. Introduction to Autonomic
... (independent) in that its activities are not under direct conscious control. It is concerned primarily with visceral functions—cardiac output, blood flow to various organs, digestion, etc—that are necessary for life. The somatic division is largely concerned with consciously controlled functions suc ...
... (independent) in that its activities are not under direct conscious control. It is concerned primarily with visceral functions—cardiac output, blood flow to various organs, digestion, etc—that are necessary for life. The somatic division is largely concerned with consciously controlled functions suc ...
The Most Dangerous Drug
... public, would refuse to license it. The ingestion of aspirin carries significant risks, and there are The Most Dangerous Drug ...
... public, would refuse to license it. The ingestion of aspirin carries significant risks, and there are The Most Dangerous Drug ...
a review on: sustained release technology
... a) Aqueous solubility and pKa A drug to be absorbed it must be dissolved in the aqueous phase surrounding the site of administration and then partition into the absorbing membrane. Two of the most important physicochemical properties of a drug that influence its absorptive behavior are its aqueous s ...
... a) Aqueous solubility and pKa A drug to be absorbed it must be dissolved in the aqueous phase surrounding the site of administration and then partition into the absorbing membrane. Two of the most important physicochemical properties of a drug that influence its absorptive behavior are its aqueous s ...
opioid receptor gene variants: lack of association with
... effect sizes at a nominal significance level of P = 0.05,27 where the effect size of the variant ALDH2*2 allele is 0.32 for DSM-III alcohol dependence.28 At this effect size, all our samples have complete power to detect association of OPRM1 variation to alcohol dependence. These results do not rule ...
... effect sizes at a nominal significance level of P = 0.05,27 where the effect size of the variant ALDH2*2 allele is 0.32 for DSM-III alcohol dependence.28 At this effect size, all our samples have complete power to detect association of OPRM1 variation to alcohol dependence. These results do not rule ...
Medication Supported Recovery
... treating the pain with buprenorphine alone. The total daily dose of buprenorphine can be increased (to a maximum of 32 mg sublingual/day); it should be given in divided doses every 6-8 hours. • Another option is to continue buprenorphine and use short-acting opioid agonists at high enough doses to o ...
... treating the pain with buprenorphine alone. The total daily dose of buprenorphine can be increased (to a maximum of 32 mg sublingual/day); it should be given in divided doses every 6-8 hours. • Another option is to continue buprenorphine and use short-acting opioid agonists at high enough doses to o ...
ALDEN, an Algorithm for Assessment of Drug Causality in Stevens
... method. Results of ALDEN scores were strongly correlated with those of the EuroSCAR case–control analysis for drugs associated with EN (r = 0.90, P < 0.0001), with probable causality being reported in 218/329 exposures. ALDEN excluded causality in 321 drugs that the case–control analysis had describ ...
... method. Results of ALDEN scores were strongly correlated with those of the EuroSCAR case–control analysis for drugs associated with EN (r = 0.90, P < 0.0001), with probable causality being reported in 218/329 exposures. ALDEN excluded causality in 321 drugs that the case–control analysis had describ ...
View the article - Jefferson Digital Commons
... hereditary etiologies), fetal growth retardation, and prematurity. These clinical problems occur commonly in the general population and, therefore, environmental causes are not always easy to corroborate (Table 15.1). Severe congenital malformations occur in 3 % of births; according to the Center fo ...
... hereditary etiologies), fetal growth retardation, and prematurity. These clinical problems occur commonly in the general population and, therefore, environmental causes are not always easy to corroborate (Table 15.1). Severe congenital malformations occur in 3 % of births; according to the Center fo ...
Jennifer Olson 1 Psychotropic Medication: Magic Bullet to Treat
... There was an important difference between psychotropic drugs and true “magic bullet” medications like insulin and malaria drugs, mainly unlike traditional drugs; psychotropic drugs were created before a disease process was even known.28 In fact, the theories of the etiology of mental illness develop ...
... There was an important difference between psychotropic drugs and true “magic bullet” medications like insulin and malaria drugs, mainly unlike traditional drugs; psychotropic drugs were created before a disease process was even known.28 In fact, the theories of the etiology of mental illness develop ...
Express Results™ Integrated Multi-Drug Screen
... Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamines: epine ...
... Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural catecholamines: epine ...
Review of Principles
... Understand the theoretical basis of drugreceptor interactions. Understand the determinants and types of responses to drug-receptor interactions. Know the four major families of receptors. Define potency and efficacy. Understand how to compare drug potency and efficacy. Understand the consequences of ...
... Understand the theoretical basis of drugreceptor interactions. Understand the determinants and types of responses to drug-receptor interactions. Know the four major families of receptors. Define potency and efficacy. Understand how to compare drug potency and efficacy. Understand the consequences of ...
Chapter 20: Gene Delivery Into The Brain Using Viral Vectors
... The delivery of recombinant genes into the brain is becoming an increasingly important strategy for answering questions about the molecular mechanisms of brain function. Answers to these questions may be applied to many of the disorders that affect the brain. For example, an understanding of the mec ...
... The delivery of recombinant genes into the brain is becoming an increasingly important strategy for answering questions about the molecular mechanisms of brain function. Answers to these questions may be applied to many of the disorders that affect the brain. For example, an understanding of the mec ...
MDMA-assisted psychotherapy - Multidisciplinary Association for
... • MDMA or placebo administered during 8 hour “experimental session” with male and female therapist present • 11 additional non-drug therapy sessions in Stage 1. 9 additional in Stage 2 • Screening and outcome measures by psychologist not involved in treatment ...
... • MDMA or placebo administered during 8 hour “experimental session” with male and female therapist present • 11 additional non-drug therapy sessions in Stage 1. 9 additional in Stage 2 • Screening and outcome measures by psychologist not involved in treatment ...
Final+Draft - EBL
... This medication should be taken 3 times a day, by mouth. It may take a few hours before the full benefit of the drug takes effect. ...
... This medication should be taken 3 times a day, by mouth. It may take a few hours before the full benefit of the drug takes effect. ...
Serotonin research: contributions to understanding psychoses
... and notably also in the pathophysiology of schizophrenia [22]. Because, as discussed later, these hallucinogenic effects seem to be related primarily to agonist actions at serotonin receptors, the long-standing serotonin hypothesis of at least the incipient stages of schizophrenia remains viable tod ...
... and notably also in the pathophysiology of schizophrenia [22]. Because, as discussed later, these hallucinogenic effects seem to be related primarily to agonist actions at serotonin receptors, the long-standing serotonin hypothesis of at least the incipient stages of schizophrenia remains viable tod ...
Behavioral Profiles in Rats Distinguish Among “Ecstasy
... 2007; Karlsen, Spigset, & Slørdal, 2008; Rogers et al., 2009; Wu et al., 2009), which are usually induced in animal models after chronic administration regimens (Green et al., 2003). The latter certainly do not mimic MDMA use by humans (Parrott, 2001), and are associated with essentially different m ...
... 2007; Karlsen, Spigset, & Slørdal, 2008; Rogers et al., 2009; Wu et al., 2009), which are usually induced in animal models after chronic administration regimens (Green et al., 2003). The latter certainly do not mimic MDMA use by humans (Parrott, 2001), and are associated with essentially different m ...
Hydroxyzine-Induced Dystonia
... gastro-intestinal tract with a peak blood-level of about two hours after oral administration [3]. Common adverse-effects of hydroxyzine in children include adverse central nervous system effects, causing sedation, decreased cognitive function and increased subjective somnolence [4]. However a few ca ...
... gastro-intestinal tract with a peak blood-level of about two hours after oral administration [3]. Common adverse-effects of hydroxyzine in children include adverse central nervous system effects, causing sedation, decreased cognitive function and increased subjective somnolence [4]. However a few ca ...
Beta-lactam antibiotics
... of the face, neck and trunk, a reaction which occurs during the infusion, and may be associated with hypotension. Nephrotoxicity and ototoxicity may occur in < 1% of pts especially those receiving other "toxic' drugs like aminoglycosides. A relationship between vancomycin level and nephrotoxicity or ...
... of the face, neck and trunk, a reaction which occurs during the infusion, and may be associated with hypotension. Nephrotoxicity and ototoxicity may occur in < 1% of pts especially those receiving other "toxic' drugs like aminoglycosides. A relationship between vancomycin level and nephrotoxicity or ...
Therapy of peptic ulcer
... The oral dose in peptic ulcer is 300 mg for 4-8 weeks, then, 150 mg daily for 6 months or more as maintenance dose. )Ranitidine doesn’t significantly affect the cytochrome oxidase P-450, thus the subsequent drug interactions are not reported. The risk of untoward antiandrogenic effects and hyperprol ...
... The oral dose in peptic ulcer is 300 mg for 4-8 weeks, then, 150 mg daily for 6 months or more as maintenance dose. )Ranitidine doesn’t significantly affect the cytochrome oxidase P-450, thus the subsequent drug interactions are not reported. The risk of untoward antiandrogenic effects and hyperprol ...
Safer Prescribing of Antidepressants Guidelines
... effectiveness and safety of antidepressant use. It is not intended to be comprehensive in scope. These recommendations are not a substitute for clinical judgment, and decisions about care must carefully consider and incorporate the clinical characteristics and circumstances of each individual. INTRO ...
... effectiveness and safety of antidepressant use. It is not intended to be comprehensive in scope. These recommendations are not a substitute for clinical judgment, and decisions about care must carefully consider and incorporate the clinical characteristics and circumstances of each individual. INTRO ...
Ergogenic Aids
... periods of time, less liver toxicity, and less potency than oral steroids.ll Injectable preparations can be detected for a month after discontinuation, whereas oral doses are detectable up to 14 days after discontinuation. Athletes rely heavily on rumors or anecdotal experiences to guide their dosag ...
... periods of time, less liver toxicity, and less potency than oral steroids.ll Injectable preparations can be detected for a month after discontinuation, whereas oral doses are detectable up to 14 days after discontinuation. Athletes rely heavily on rumors or anecdotal experiences to guide their dosag ...
Product Insert - Drug testing supplies from CLIA waived,Inc, drug tests
... AMPHETAMINE (AMP) Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural cat ...
... AMPHETAMINE (AMP) Amphetamine is a Schedule II controlled substance available by prescription (Dexedrine®) and is also available on the illicit market. Amphetamines are a class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body’s natural cat ...
Medicare Part D and Prescription Drug Utilization
... the past year, how often did you stop taking a prescription medication because of cost?” (never, 1-2 times, 3-4 times, more than 4 times); “In the past year, how often did you skip doses of a prescription medication in order to save money?” (never, 1-2 times, 3-4 times, more than 4 times). The seco ...
... the past year, how often did you stop taking a prescription medication because of cost?” (never, 1-2 times, 3-4 times, more than 4 times); “In the past year, how often did you skip doses of a prescription medication in order to save money?” (never, 1-2 times, 3-4 times, more than 4 times). The seco ...
Indirect cholinomimetics-level I
... • All phosphates are lipid soluble except ecothiophate which is polar. • Some of them are used as pesticides. ...
... • All phosphates are lipid soluble except ecothiophate which is polar. • Some of them are used as pesticides. ...
Discriminative Stimulus Properties of Cocaine
... to discriminate either low or high doses of cocaine from saline, although it has not been reported to antagonize the DS effects of cocaine in rats. It could be that species and/or training conditions are important determinants of the extent that NE is involved in the DS effects of cocaine. Nonethele ...
... to discriminate either low or high doses of cocaine from saline, although it has not been reported to antagonize the DS effects of cocaine in rats. It could be that species and/or training conditions are important determinants of the extent that NE is involved in the DS effects of cocaine. Nonethele ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.