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Title
Title

... and therapeutic uses of drugs which act directly on ion channels, for example local anaesthetics, anti-arrhythmic agents, calcium channel blockers and diuretics (3 hours) Drugs acting via receptors and second messengers: an overview of the potential therapeutic uses and adverse effects of drugs whic ...
Slide 1
Slide 1

... used as a medicine for the treatment of disease. • In a larger context: A substance taken because of its biologically active properties. This would include substances such as caffeine, nicotine, alcohol, cannabis, heroin and cocaine. ...
CM 21- Stimulants, Benzo, Barbs, Opiates, Heroin Psychostimulants
CM 21- Stimulants, Benzo, Barbs, Opiates, Heroin Psychostimulants

... Speed, meth, ice crystal, crank, chalk Pseudoephedrine, phenylpropanolamine, and ephedrine Better regulated = decreased manufacture Short term effects = releases dopamine o Increases wakefulness; decreases appetite o Oral or snorting long-lasting high o Injecting gm every 2-3 hours (“run”) o Long la ...
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Drug Dosage and Clinical Responses

... • Potency refers to the amount of drug necessary to produce a certain effect. A drug which produces a certain effect at 5 mg dosage is ten times more potent than a drug which produces the same effect at 50 mg dosage. • Clinical efficacy (or simply efficacy) refers to the maximal clinical response th ...
Pharmacology
Pharmacology

... by interacting with other chemicals in the body is called mechanism of action (MOA).  Pharmacotherapeutics= the study of the effects of drugs  Drugs that have the same MOA belong to the same therapeutic class (Ex- Benadryl and Claritin belong to the class of antihistamines which work by binding to ...
Practice Exam Each question is worth 4 points unless otherwise
Practice Exam Each question is worth 4 points unless otherwise

... 12. At metabotropic synapses, second messengers are activated in postsynaptic neurons by a. electrical currents. b. specific enzymes. c. mitochondria. d. transmitter–receptor combinations. 13. The generation of the action potential depends on ________ ________ _________ channels. 14. Transporter mo ...
What do you know about ECSTASY?
What do you know about ECSTASY?

... –plants used in religious ceremonies and as part of indian rituals –LSD discovered in 1938; Hoffman absorbed it –became widely recognized and used in 1960s –e.g., cultish subculture: T. Leary--turn on, tune in, drop out –reemergence of LSD in rave subculture in 1990s –uses of LSD, X in psychotherapy ...
Legal Highs: Harms and Effects
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... beat). There are also reported circulatory problems from more regular users including cold hands and ‘burning’ feet. Prolonged use can affect your mental capacity. You may become paranoid or delusional or in some extreme cases develop a kind of psychosis. Harms Relatively little is known about the h ...
CNS Depressants/Antianxiety Agents
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FACTORS THAT CHANGE DRUG ACTION

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... The main phases of substance abuse treatment are detoxification/stabilization, rehabilitation and continuing care. The published scientific literature provides evidence of effective treatment components with the length of stay being the clearest predictor of beneficial effects from treatment. Treatm ...
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MLAB 2401: Clinical Chemistry Keri Brophy

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... Caffeine is perhaps the most popular, as well as one of the most ancient, drugs. Nearly everyone ingests this drug every day in the form of coffee, tea, cocoa, soft drinks, or headache remedies. The drug occurs naturally in more than 60 plants and trees that have been cultivated by humans since the ...
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Phychiatric Drugs. Central Nervous System

... eliminated by first-order kinetics. The half-life of caffeine varies widely among individuals according to such factors as age, liver function, pregnancy, some concurrent medications, and the level of enzymes in the liver needed for caffeine metabolism. In healthy adults, caffeine's halflife is appr ...
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Psychoactive Drugs

... Drugs should be tapered to prevent withdrawal symptoms / DT’s  Drugs can store in fat cells and prolong withdrawal symptoms  Dosages ½ to 1/3rd. for elderly  Instruct about risk of addiction /safety from falls ...
Interactions Between Pain Medications And Illicit Street Drugs
Interactions Between Pain Medications And Illicit Street Drugs

... some are decreased (ie, protease inhibitors, various xanthines including theophylline). This may result in additive central nervous system (CNS) depression or sedation, especially when marijuana is used with barbiturates, anticholinergic agents, and alcohol or other CNS depressants. More serious int ...
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Bath Salts and Spice

... Monitoring Centre for Drugs and Drug Addiction. 27 May 2010. Psychonaut WebMapping Research Group (2009). MDPV report. Institute of Psychiatry, King’s College London: London UK. Available at: www.nascsa.org/news/psychonautmdpvreport.pdf. Accessed February 23, 2011. Psychonaut WebMapping Research Gro ...
Motivation - HomePage Server for UT Psychology
Motivation - HomePage Server for UT Psychology

... • Activate the sympathetic nervous system • Interfere with the normal reuptake of dopamine by the releasing neuron • Some stimulants also increase the release of dopamine • Caffeine, cocaine, amphetamines ...
Biol. Psychist. __, No.3, pp.243-246 (1972).
Biol. Psychist. __, No.3, pp.243-246 (1972).

... episodes during the second half of the night. EEG sleep patterns on recovery nights following large doses of tryptophan were not systematically different from baseline nights. These results indicate that the changes in sleep patterns produced by Ltryptophan, presumably acting through 5-hydroxyindole ...
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20.b) SYMPATHETIC NERVOUS SYSTEM, ALFA AND BETA

... b. Pulmonary: Bronchodilation, is less potent than epinephrine or isoproterenol and produces its action more slowly. Therefore used prophylactically in chronic treatment of asthma. c. Skeletal muscle: ↑ contractility and improves motor function in Myasthenia gravis (particularly when used with antic ...
Current and Upcoming Approaches to Medically Supervised
Current and Upcoming Approaches to Medically Supervised

... Tetraethylthiuram - Synthesized by Danish scientists in the 1930’s as an antihelminthic; a non-specific inhibitor of sulfhydryl-containing enzymes ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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