Pharmacokinetics
... Two Drug Agonists Attach to the Receptor Site. The drug agonist that has an exact fit is a strong agonist and is more biologically active than the weak agonist. ...
... Two Drug Agonists Attach to the Receptor Site. The drug agonist that has an exact fit is a strong agonist and is more biologically active than the weak agonist. ...
Uppers, Downers, All Arounders, 7th Edition
... This chapter surveys the various stimulants, their history, effects and side effects, and the social context of their use. General Effects Uppers are stimulants that initially increase energy and alertness. These are the world’s most widely used psychoactive drugs. Some give an intense rush while ot ...
... This chapter surveys the various stimulants, their history, effects and side effects, and the social context of their use. General Effects Uppers are stimulants that initially increase energy and alertness. These are the world’s most widely used psychoactive drugs. Some give an intense rush while ot ...
Dopamine Theory of Schizophrenia
... Dopamine Theory of Schizophrenia Schizophrenia is caused by too much dopamine (DA) DA antagonists are effective neuroleptics (antischizoprenic drugs) – Chlorpromazine – Reserpine ...
... Dopamine Theory of Schizophrenia Schizophrenia is caused by too much dopamine (DA) DA antagonists are effective neuroleptics (antischizoprenic drugs) – Chlorpromazine – Reserpine ...
Bertha K. Madras, PhD
... Journal of Substance Use, Advance online publication (doi:10.3109/14659891.2013.770571), 2013. For more information, contact Dr. Stogner at [email protected]. ...
... Journal of Substance Use, Advance online publication (doi:10.3109/14659891.2013.770571), 2013. For more information, contact Dr. Stogner at [email protected]. ...
Detoxification/Withdrawal
... What happens with alcohol overdose? Increasing BAC leads to increasing sedating ...
... What happens with alcohol overdose? Increasing BAC leads to increasing sedating ...
Suntheanine FS - Doctor`s Best Vitamins
... face of induced oxidative stress. In one such experiment, cultured rat neurons were exposed to glutamic acid, resulting in significant cellular death. When these cells were simultaneously exposed to L-theanine, the cell death was suppressed4. This antioxidant effect may yield a partial glimpse into ...
... face of induced oxidative stress. In one such experiment, cultured rat neurons were exposed to glutamic acid, resulting in significant cellular death. When these cells were simultaneously exposed to L-theanine, the cell death was suppressed4. This antioxidant effect may yield a partial glimpse into ...
It`s official: high potency ecstasy makes a comeback
... ecstasy pills recovered, in 25 separate seizures, contained high levels of MDMA more common in pills made in the 1980s and 1990s. “It is rare these days to get ecstasy pills that contain MDMA, but this year we were surprised because most of the pills did,” Bunt said. The findings back up mounting an ...
... ecstasy pills recovered, in 25 separate seizures, contained high levels of MDMA more common in pills made in the 1980s and 1990s. “It is rare these days to get ecstasy pills that contain MDMA, but this year we were surprised because most of the pills did,” Bunt said. The findings back up mounting an ...
DRUG A - University of Kentucky
... • Excretion – Glomular filtration rate varies with body weight ...
... • Excretion – Glomular filtration rate varies with body weight ...
Antidepressant Drugs
... Phenelzine and isocarboxazide (no longer marketing), they bound irreversibly to MAO (A and B) with prolonged duration of action . Tranylcypromine which bound reversibly to MAO(A and B) with long duration of action. B-Selective inhibitors of MAO: -Selegiline is selective for MAO-B at low doses, but a ...
... Phenelzine and isocarboxazide (no longer marketing), they bound irreversibly to MAO (A and B) with prolonged duration of action . Tranylcypromine which bound reversibly to MAO(A and B) with long duration of action. B-Selective inhibitors of MAO: -Selegiline is selective for MAO-B at low doses, but a ...
Drugs of Abuse 2 CEUs
... Treatment is largely supportive with airway and respiratory protection being paramount. Sedative intoxication can cause peripheral vasodilatation as well. Blood pressure and heart rate need to be closely monitored. IV fluids may be necessary. This is especially true in the case of alcohol, which cau ...
... Treatment is largely supportive with airway and respiratory protection being paramount. Sedative intoxication can cause peripheral vasodilatation as well. Blood pressure and heart rate need to be closely monitored. IV fluids may be necessary. This is especially true in the case of alcohol, which cau ...
Are You Drug Smart? - Do It Now Foundation
... 1. “Special K” is a PCP-like drug that can cause users to believe they’ve been contacted by extraterrestrials. ...
... 1. “Special K” is a PCP-like drug that can cause users to believe they’ve been contacted by extraterrestrials. ...
AmphetAmines (speed, ice)
... In the short term, cocaine can produce increased heart rate, paranoia, agitation, dilated pupils,hallucinations, tremors, muscle twitches, nausea and vomiting. The immediate effects of the drug can intensify when it’s taken in larger quantities, and can produce an irregular heartbeat, chest pain, hy ...
... In the short term, cocaine can produce increased heart rate, paranoia, agitation, dilated pupils,hallucinations, tremors, muscle twitches, nausea and vomiting. The immediate effects of the drug can intensify when it’s taken in larger quantities, and can produce an irregular heartbeat, chest pain, hy ...
Arylalkylamine Drugs of Abuse: An Overview of Drug
... which arylalkylamines produce a common effect. To this extent we employed the drug discrimination paradigm, with animals trained to a suitable training drug, to determine which agents produce stimulus effects similar to those of a known hallucinogen. However, the question immediately arises as to wh ...
... which arylalkylamines produce a common effect. To this extent we employed the drug discrimination paradigm, with animals trained to a suitable training drug, to determine which agents produce stimulus effects similar to those of a known hallucinogen. However, the question immediately arises as to wh ...
drug abuse - Rocky and District Victim Services
... Mental Hazards: Some drugs can cause shortterm confusion, anxiety or even severe mental disturbance which can result in personality changes and loss of memory. Physical Dependence: Without the drug, the user may experience a variety of symptoms ranging from mild discomfort to convulsions, some of wh ...
... Mental Hazards: Some drugs can cause shortterm confusion, anxiety or even severe mental disturbance which can result in personality changes and loss of memory. Physical Dependence: Without the drug, the user may experience a variety of symptoms ranging from mild discomfort to convulsions, some of wh ...
STIMULANTS: Amphetamines, Cocaine (p.1) 1. History of
... vasoconstriction --- decreased placental blood flow --- decreased O2 to fetus increased risk for placental detachment, preterm labor, stillborns, decreased birth weight, microcephaly, cardiovascular damage to fetus teratogenic effects & fetotoxic effects are noted question – would fetus have reduced ...
... vasoconstriction --- decreased placental blood flow --- decreased O2 to fetus increased risk for placental detachment, preterm labor, stillborns, decreased birth weight, microcephaly, cardiovascular damage to fetus teratogenic effects & fetotoxic effects are noted question – would fetus have reduced ...
Not my Kid Powerpoint - Chardon Local Schools
... overdose will be the leading cause of death by accident. ...
... overdose will be the leading cause of death by accident. ...
History of psychopharmacology
... Psychopharmacology originated in the early nineteenth century with the recreational and experimental human use of organic drugs and medicines (Muller, Fletcher, & Steinberg, 2006). Plant-derivatives such as tea and opium were freely accessible in the oriental region; tobacco and coffee in America an ...
... Psychopharmacology originated in the early nineteenth century with the recreational and experimental human use of organic drugs and medicines (Muller, Fletcher, & Steinberg, 2006). Plant-derivatives such as tea and opium were freely accessible in the oriental region; tobacco and coffee in America an ...
Drugs Affecting the Central Nervous System #1
... • The precursor of DA that is taken orally and converted into DA in the basal ganglia • Administered in combination with carbidopa that increases the amount of DA that enters the brain • Levodopa and carbidopa drug combination known as Sinemet • Levodopa is considered the most effective drug for the ...
... • The precursor of DA that is taken orally and converted into DA in the basal ganglia • Administered in combination with carbidopa that increases the amount of DA that enters the brain • Levodopa and carbidopa drug combination known as Sinemet • Levodopa is considered the most effective drug for the ...
3 Amphetamines in the Treatment of Attention
... most frequently prescribed agents for this disorder, and highlight the new extended release product which offers the convenience of oncedaily dosing, Mechanism of Action Like methylphenidate, the mechanism of action for amphetamines in patients with ADHD is not known. Amphetamines are sympathomimeti ...
... most frequently prescribed agents for this disorder, and highlight the new extended release product which offers the convenience of oncedaily dosing, Mechanism of Action Like methylphenidate, the mechanism of action for amphetamines in patients with ADHD is not known. Amphetamines are sympathomimeti ...
Depressants
... or decrease anxiety. This drug is injected or swallowed in a pill form. Tranquilizers depress the effectiveness of the central nervous system which in turn slows the body down. ...
... or decrease anxiety. This drug is injected or swallowed in a pill form. Tranquilizers depress the effectiveness of the central nervous system which in turn slows the body down. ...
Are Stimulants Appropriate in the Elderly?
... • Mr. C. would be a good candidate for psychostimulant treatment of his depressive symptoms based on the information presented. He had no obvious contraindications to the use of stimulants, and he would most likely have benefited from their rapid onset of action. This rapid effect would have been pa ...
... • Mr. C. would be a good candidate for psychostimulant treatment of his depressive symptoms based on the information presented. He had no obvious contraindications to the use of stimulants, and he would most likely have benefited from their rapid onset of action. This rapid effect would have been pa ...
Midodrine Information Leaflet
... The dose should be increased at intervals of 3 – 5 days until the optimal response is obtained. Most patients are controlled on doses at or below 30mg daily in divided doses Doses should be taken in the morning, at noon and evening. The last dose should be taken at least four hours before be ...
... The dose should be increased at intervals of 3 – 5 days until the optimal response is obtained. Most patients are controlled on doses at or below 30mg daily in divided doses Doses should be taken in the morning, at noon and evening. The last dose should be taken at least four hours before be ...
Basic Neuroanatomy
... Inhibits reuptake of serotonin, norepinephrine, and (to some extent) dopamine Used as an anti-obesity drug with modest results Rapidly metabolized in the liver to active metabolites that are responsible for its pharmacologic action (prodrug) Metabolites reach a peak at 3-4 hours in plasma Half-life ...
... Inhibits reuptake of serotonin, norepinephrine, and (to some extent) dopamine Used as an anti-obesity drug with modest results Rapidly metabolized in the liver to active metabolites that are responsible for its pharmacologic action (prodrug) Metabolites reach a peak at 3-4 hours in plasma Half-life ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.