Mechanisms of common and important adverse drug reactions
... adverse events with medicines in nl doses • Adverse Drug Reactions – noxious and unintended; at normal therapeutic doses – Affect 2 million / yr in US; 100,000 deaths / yr ...
... adverse events with medicines in nl doses • Adverse Drug Reactions – noxious and unintended; at normal therapeutic doses – Affect 2 million / yr in US; 100,000 deaths / yr ...
Common Drugs Cocaine - Cuyahoga County Medical Examiner
... stimulant methamphetamine and the hallucinogen mescaline. MDMA is an illegal drug that acts as both a stimulant and psychedelic, producing an energizing effect, as well as distortions in time and perception and enhanced enjoyment from tactile experiences. Adolescents and young adults use it to promo ...
... stimulant methamphetamine and the hallucinogen mescaline. MDMA is an illegal drug that acts as both a stimulant and psychedelic, producing an energizing effect, as well as distortions in time and perception and enhanced enjoyment from tactile experiences. Adolescents and young adults use it to promo ...
Tina said you all learned ALOT last week
... – As repeated doses of a drug are administered its plasma concentration builds up and reaches what is known as a steady state. This is when the amount of drug in the plasma has built up to a concentration level that is therapeutically effective and as long as regular doses are administered to balanc ...
... – As repeated doses of a drug are administered its plasma concentration builds up and reaches what is known as a steady state. This is when the amount of drug in the plasma has built up to a concentration level that is therapeutically effective and as long as regular doses are administered to balanc ...
Cocaine and Amphetamines
... Acute and Chronic Effects of Amphetamines Amphetamines’ effects are similar, but not identical, to those of cocaine Stimulate CA release, block reuptake Acute effects general arousal antidepressant appetite suppressant keeps people awake for long periods of time. ...
... Acute and Chronic Effects of Amphetamines Amphetamines’ effects are similar, but not identical, to those of cocaine Stimulate CA release, block reuptake Acute effects general arousal antidepressant appetite suppressant keeps people awake for long periods of time. ...
February 2007 Toxtidbits
... controlled substances). Cases presenting to EMS providers and emergency departments with adulterated drugs are problematic in that signs and symptoms don’t correlate with the history. In many cases, toxscreens won’t confirm the presence or absence of the drugs involved. The Maryland Poison Center (M ...
... controlled substances). Cases presenting to EMS providers and emergency departments with adulterated drugs are problematic in that signs and symptoms don’t correlate with the history. In many cases, toxscreens won’t confirm the presence or absence of the drugs involved. The Maryland Poison Center (M ...
Respiratory Drugs
... enhance receptor response. NOT useful for immediate attacks b/c have NO effect on IgE stimulation pathways; work slowly and are better at preventing attacks, however if pt doesn’t respond to bronchodilators with acute attack, must give high dose corticosteroids ...
... enhance receptor response. NOT useful for immediate attacks b/c have NO effect on IgE stimulation pathways; work slowly and are better at preventing attacks, however if pt doesn’t respond to bronchodilators with acute attack, must give high dose corticosteroids ...
Ethnopharmacology Handout
... Adverse effects occur at much lower dosages. There have been few ethno-pharmacologic studies on SSRIs so it is not possible to state if they are tolerated better than SSRIs in people of Asian ancestry. Lithium Non whites require lower doses and report more lethargy and dizziness (even when blood l ...
... Adverse effects occur at much lower dosages. There have been few ethno-pharmacologic studies on SSRIs so it is not possible to state if they are tolerated better than SSRIs in people of Asian ancestry. Lithium Non whites require lower doses and report more lethargy and dizziness (even when blood l ...
Noradrenergic Transmission
... Indirect & direct acting on & receptors. - Similar to epinephrine but less potent. - Not a catecholamine drug. ...
... Indirect & direct acting on & receptors. - Similar to epinephrine but less potent. - Not a catecholamine drug. ...
Durand and Barlow Chapter 10: Substance-Related Disorders
... – Produce short lived sensations of elation, vigor, reduce fatigue – Cocaine use in the United States has declined over the last decade – Effects result from blocking the reuptake of dopamine – Cocaine is highly addictive, but addiction develops slowly ...
... – Produce short lived sensations of elation, vigor, reduce fatigue – Cocaine use in the United States has declined over the last decade – Effects result from blocking the reuptake of dopamine – Cocaine is highly addictive, but addiction develops slowly ...
CHRONOLAB AG , Zug, Switzerland, [email protected]
... provoke withdrawal symptoms, sometimes accompanied by aggressive behaviour. This may result in self-discharge against medical advice, but there is a risk of recurrent toxicity, as naloxone is much shorter acting than almost all abused opioids. Care is also needed to avoid excessive doses of naloxone ...
... provoke withdrawal symptoms, sometimes accompanied by aggressive behaviour. This may result in self-discharge against medical advice, but there is a risk of recurrent toxicity, as naloxone is much shorter acting than almost all abused opioids. Care is also needed to avoid excessive doses of naloxone ...
How to spot illicit drug abuse in your patients
... An LSD "trip" typically lasts 6 to 18 hours. The effects of psilocybin and mescaline mimic those of endogenous serotonin and can last 8 to 12 hours (1). All of these agents may produce highly variable effects, depending on the dose taken as well as the mood and environment of the user at the time of ...
... An LSD "trip" typically lasts 6 to 18 hours. The effects of psilocybin and mescaline mimic those of endogenous serotonin and can last 8 to 12 hours (1). All of these agents may produce highly variable effects, depending on the dose taken as well as the mood and environment of the user at the time of ...
Pharm Test 2 - Glory Cubed Productions
... They work almost instantaneously because of the enormous surface area of the bronchioles and alveoli and the rich blood supply to them. 1. Aerosol – suspension of minute liquid droplets or fine solid particles suspended in a gas for an immediate onset of action. 2. Nebulizer – small machine that vap ...
... They work almost instantaneously because of the enormous surface area of the bronchioles and alveoli and the rich blood supply to them. 1. Aerosol – suspension of minute liquid droplets or fine solid particles suspended in a gas for an immediate onset of action. 2. Nebulizer – small machine that vap ...
What do you know about ECSTASY?
... –plants used in religious ceremonies and as part of indian rituals –LSD discovered in 1938; Hoffman absorbed it –became widely recognized and used in 1960s –e.g., cultish subculture: T. Leary--turn on, tune in, drop out –reemergence of LSD in rave subculture in 1990s –uses of LSD, X in psychotherapy ...
... –plants used in religious ceremonies and as part of indian rituals –LSD discovered in 1938; Hoffman absorbed it –became widely recognized and used in 1960s –e.g., cultish subculture: T. Leary--turn on, tune in, drop out –reemergence of LSD in rave subculture in 1990s –uses of LSD, X in psychotherapy ...
e355f9743c0c09557df86918e6a1c93b - Health
... cramps, insomnia, diarrhoea, and vomiting. In large doses, heroin toxicity (overdose) may occur due to the depressant action of heroin on the CNS, which may lead to coma and potentially, death. The risk of overdosing increases with the concurrent use of other CNS depressants (such as alcohol), great ...
... cramps, insomnia, diarrhoea, and vomiting. In large doses, heroin toxicity (overdose) may occur due to the depressant action of heroin on the CNS, which may lead to coma and potentially, death. The risk of overdosing increases with the concurrent use of other CNS depressants (such as alcohol), great ...
drug use and abuse - North Allegheny School District
... that includes visual distortions and a lost sense of time, sense and identity. Profound physical and mental problems including delirium, amnesia, impaired motor function and potentially fatal problems Special K is a powder that is usually snorted but is sometimes sprinkled on tobacco or marijuana an ...
... that includes visual distortions and a lost sense of time, sense and identity. Profound physical and mental problems including delirium, amnesia, impaired motor function and potentially fatal problems Special K is a powder that is usually snorted but is sometimes sprinkled on tobacco or marijuana an ...
Antidepressants and Anxiolytics
... – Newer: long term or lifelong therapy – Distinguish: situational/transient depression ...
... – Newer: long term or lifelong therapy – Distinguish: situational/transient depression ...
Psychoactive Drugs Notes
... How do they work? drugs change the way our neurotransmitters work neurotransmitter: chemicals that neurons use to communicate with each other ...
... How do they work? drugs change the way our neurotransmitters work neurotransmitter: chemicals that neurons use to communicate with each other ...
Dr. Keith Baker - Designer (Dirty) Drugs
... analogue of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while at the same time avoiding being classified as illegal, and/or avoid detection on standard drug test” ...
... analogue of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while at the same time avoiding being classified as illegal, and/or avoid detection on standard drug test” ...
substance abuse - Molloy College
... feels he has gotten involved with the “wrong crowed” and she can no longer reach him. Jake does not see any problems and is annoyed with his mother. He denies drug use but acknowledges that his peers are involved with “some stuff” but can not or will not explain further. ...
... feels he has gotten involved with the “wrong crowed” and she can no longer reach him. Jake does not see any problems and is annoyed with his mother. He denies drug use but acknowledges that his peers are involved with “some stuff” but can not or will not explain further. ...
drug abuse - Leduc Victim Services
... Flunitrazepam (Rohypnol): Is ingested orally usually with alcohol or other drugs. Commonly called the rape pill, roofies and the forget pill. The drug’s effects begin within 30 minutes, peak within 2 hours and may last up to 8 hours or more. Side effects include decreased blood pressure, memory impa ...
... Flunitrazepam (Rohypnol): Is ingested orally usually with alcohol or other drugs. Commonly called the rape pill, roofies and the forget pill. The drug’s effects begin within 30 minutes, peak within 2 hours and may last up to 8 hours or more. Side effects include decreased blood pressure, memory impa ...
Drug development
... isomers, pKa, stability, solubility, salts, assay • BIOLOGICAL; acute pharmacological profile LD50, ED50, binding data for many receptors, dose-effect relationships, open field tests, particular tests for different activities (e.g. CVS, CNS, GI tract) Both positive and negative information is useful ...
... isomers, pKa, stability, solubility, salts, assay • BIOLOGICAL; acute pharmacological profile LD50, ED50, binding data for many receptors, dose-effect relationships, open field tests, particular tests for different activities (e.g. CVS, CNS, GI tract) Both positive and negative information is useful ...
medication administration
... The therapeutic effect of the drug is the intended use of the drug, that is , its desired effect. E.g. Panadol for a headache, the therapeutic effect is pain relief. ...
... The therapeutic effect of the drug is the intended use of the drug, that is , its desired effect. E.g. Panadol for a headache, the therapeutic effect is pain relief. ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.