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Clopixol-Acuphase® 50 mg/ml Zuclopenthixol acetate
Clopixol-Acuphase® 50 mg/ml Zuclopenthixol acetate

... In the maintenance therapy, treatment should be continued with oral zuclopenthixol or zuclopenthixol decanoate i.m., after the following guidelines: 1) Change to oral zuclopenthixol 2 to 3 days after the last injection of zuclopenthixol acetate a patient who has been treated with 100 mg zuclope ...
Oxycodone - getuponit.ca
Oxycodone - getuponit.ca

... Oxycodone is in a group of drugs known as opioids or narcotic analgesic pain relievers. It is a drug available in liquid, tablet and capsule form used to medically relieve moderate to severe short term and long term pain. It reduces pain by working on the central nervous system and changing the way ...
Capsicum
Capsicum

... In peripheral nervous system nociceptive nerve endings coil around the cranial blood vessels and are activated when the blood vessels dilate Stimulation of the 5-HT1D receptors inhibits the release of chemicals that cause pain and inflammation, such as substance P and others ...
Allergic Rhinitis
Allergic Rhinitis

... • A drug that reduces or eliminates the effects mediated by the chemical histamine • Histamine is released by our body during an allergic reaction and acts on a specific histamine receptor • True antihistamines are only the agents that produce a therapeutic effect that is mediated by negative modula ...
Inappropriate Medications
Inappropriate Medications

... diazepam produce prolonged sedation (often lasting several days and can worsen if taken daily) and can increase the risk of falls and fractures. ...
Psychopharmacology - Ohio State University
Psychopharmacology - Ohio State University

... observed (Jamaicans think of it as appetite suppressant). • In a study, 9 male subjects were given THC-containing cigarettes either (1) before a private work period, or (2) during access to social periods with other subjects. (1) did not lead to increased food intake (2) did lead to increased food i ...
Antiinflammatory Drugs
Antiinflammatory Drugs

... very little antiinflammatory activity; oxidation by cyp-450 pathway releases a reactive metabolite that causes centrilobular hepatic necrosis, unless it’s detoxified by glutathione Phenacetin -- not used any more because of its toxicities * N-Acetylcysteine can be used to treat acetaminophen poisoni ...
NIDA Research Report - Hallucinogens and
NIDA Research Report - Hallucinogens and

... LSD use also produces tolerance for other hallucinogenic drugs such as psilocybin and mescaline, but not to drugs such as marijuana, amphetamines, and PCP, which do not act directly on the serotonin receptors affected by LSD. Tolerance for LSD is shortlived—it is lost if the user stops taking the dr ...
Postgraduate Course ERS Copenhagen 2005 The side
Postgraduate Course ERS Copenhagen 2005 The side

... without significant side-effects. There is also an opposing view that most patients with TB complete their treatment without serious adverse effects. What is the truth? Modern anti-TB chemotherapy regimens have been in use for >30 years. However, the frequency of severe complications is not well kno ...
Title : Involvement of D1 dopamine receptor in
Title : Involvement of D1 dopamine receptor in

... transferase), Fos, FosB, Egr1 and Egr2 have been previously described (Salzmann et al, 2003; Salzmann et al 2006). Fluorescent PCR reactions were performed on a 7900HT system (Applied Biosytems, France) using the Power SYBR® Green PCR Master mix kit (Applied Biosytems, France). The cDNAs were dilute ...
ABC`s of Drug Testing
ABC`s of Drug Testing

... • d-isomers are CNS active and are abused • l-isomers have 10% of d-isomer activity in CNS, but work better peripherally, so are used in nasal inhalers • Isomers may be differentiated by immunoassays or by chiral-specific methods • Isomeric form is preserved throughout metabolism ...
Colloids
Colloids

... • Refers the the proportion of molecules that  are hydroxyethylated at the C2 vs he C6  position. • A higher C2:C6 ratio results in longer  intravascular half life. ...
Adenosine Pharmacology
Adenosine Pharmacology

... • Increase heart rate with nicotine. • Higher degrees of heart block in the presence of carbamazepine Guidelines and precautions: Do not confuse this drug with adenosine phosphate, which is used as adjunctive therapy in the treatment of complications associated with varicose veins. Due to the rapid ...
neuromuscular blocking agents and muscle relaxants
neuromuscular blocking agents and muscle relaxants

... It produces a selective block on the peripheral sympathetic nervous system. 1. Pharmacological effects • It is taken up by adrenergic nerve terminals  blocks of the release of NE • It also inhibits the reuptake of NE into the nerve terminal • Initially it produces sympathomimetic effect 2. Therapeu ...
MUSCARINIC RECEPTOR ANTAGONISTS:
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... active metabolite. (genetic polymorphism – 70 % of pop’n are poor metabolizers  Cyp3A4 is the minor p/s  Active N-dealkylation ...
The Cerebral Cortex and Higher Intellectual Functions
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... • The study of the influence of various kinds of drugs has provided us with knowledge about many aspects of neural communication at the synaptic level. • Drugs either facilitate or inhibit activity at the synapse. – Antagonistic drugs block the effects of neurotransmitters (e.g., novacaine, caffeine ...
Adverse Effects
Adverse Effects

... Recap: Pathophysiology of Pituitary Gland  Anterior pituitary gland dysfunction:  Includes growth hormone deficiency and excess.  Posterior pituitary gland dysfunction:  Major disorders are diabetes insipidus (DI) and syndrome of inappropriate antidiuretic hormone (SIADH).  Thyroid gland dysfu ...
Drug and Alcohol Preventation Handbook
Drug and Alcohol Preventation Handbook

... a car safely, increasingly the likelihood that the driver will be involved in an accident. Low to moderate doses of alcohol also increase the incidence of a variety of aggressive acts. Moderate to high doses of alcohol cause marked impairments in higher mental functions severely altering a person’s ...
ANTI-INFLAMMATORY DRUGS Inflammation is the complex
ANTI-INFLAMMATORY DRUGS Inflammation is the complex

... in synovial fluid, and the primary route of excretion for the drug and its metabolites is the kidney. Tolmetin is an effective anti-inflammatory, antipyretic, and analgesic agent with a halflife of 5 hours. It is 99 percent bound to plasma proteins, and metabolites can be found in the urine. Ketorol ...
57591c0c-051f-4ae8-8765
57591c0c-051f-4ae8-8765

... • 6)Salicylate:large dose in mice is teratogenic or can lead to resorption of the embryo.Na salicylate (acute rheumatic fever),the dose used, wt for wt approaches that which is teratogenic in pregnant mice.A study from CANADA reported premature closure of the ductus arteriosis, pulmonary hypertensio ...
Medications - Delaware Association of Home and Community Care
Medications - Delaware Association of Home and Community Care

... • Drug-Drug Interactions-Changes in a drug’s effects when two (or more) drugs are taken at the same time. levothyroxin taken with metformin = effect of metformin = blood sugar ...
Multiple drug interactions modulate P450 activity
Multiple drug interactions modulate P450 activity

... fungal infection) and Triazolam (an antipsychotic also used for insomnia). All three of these drugs bind to CYP3A4. Ketoconazole inhibits CYP3A4 and caused the other two drugs to become overdosed during 6 hr flight (sitting still is a ...
Pharmacokinetic Phase
Pharmacokinetic Phase

... • Function of both the liver and kidneys must be known ...
Drug Testing - ACL Laboratories
Drug Testing - ACL Laboratories

... Note: There are no legal medical uses of PCP or any other substance that can be misidentified as PCP. Drug screen panels and tests are available with the following options: 1. Drug screen panels and tests with order codes beginning with “U” do not require an accompanying Chain of Custody, nor do the ...
Slide 1
Slide 1

... fungal infection) and Triazolam (an antipsychotic also used for insomnia). All three of these drugs bind to CYP3A4. Ketoconazole inhibits CYP3A4 and caused the other two drugs to become overdosed during 6 hr flight (sitting still is a ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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