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Opioid painkillers: How they work and why they can be risky
Opioid painkillers: How they work and why they can be risky

... Franklin, Gary M., Enass A. Rahman, Judith A. Turner, William E. Daniell, and Deborah Fulton– Kehoe. 2009. “Opioid Use for Chronic Low Back Pain: A Prospective, Population-Based Study Among Injured Workers in Washington State, 2002–05.” Clinical Journal of Pain 25(9):743–51. Gelfand, Stephen G. N.d. ...
TB lecture - Mayo Clinic Center for Tuberculosis
TB lecture - Mayo Clinic Center for Tuberculosis

... HIV-infected patients have serum concentrations lower than healthy volunteers, but still respond well to standard treatment regimens ...
dagga - SANCA Bloemfontein
dagga - SANCA Bloemfontein

... • Illegal drugs e.g. dagga, mandrax, LSD, heroin, ...
Antiparkinsonian Drugs
Antiparkinsonian Drugs

... inhibitory control, aspects of attention, and planning latency) It also improves task saliency and performance on tedious tasks that require a high degree of effort. Eugeroics (armodafinil and modafinil) – wakefulness promoting agents; They are clinically prescribed for narcolepsy, shift work sleep ...
Alpha Receptors, Beta Receptors, Kappa Receptors
Alpha Receptors, Beta Receptors, Kappa Receptors

... Possible new treatment, not yet FDA approved: Memantine (Namenda) for migraines • Females have a lower threshold for a phenomenon called cortical spreading depression (CSD)—bursts of intense electrical activity across the cortex resulting in migraines • Memantine (Namenda) blocks CSD • Clinical tri ...
Respiratory drugs-nursing
Respiratory drugs-nursing

... - Inhibit release of inflammatory mediator or broncho constricting substances from mast cells. - Inhibit microvasculature leakage - Increase mucociliary transport a. Non-selective β- agonists - Cause more cardiac stimulation (mediated by a β1 receptor), they should be reserved for special situation. ...
03 Motor Symptoms PD SLIDES
03 Motor Symptoms PD SLIDES

... • Aim of treatment of motor symptoms is to restore dopamine levels • Treatment choice will depend on age, symptoms, comorbidities and patient wishes • As disease progresses the number of medications and adjustments required will increase • It is extremely important that medications are managed well ...
Cardiovascular System Drugs – Summary
Cardiovascular System Drugs – Summary

... o GTN – well absorbed from the gut but undergoes extensive first pass metabolism in liver producing inactive metabolites o To increase bioavailability GTN is given via three methods:  Sub lingual: Tablet placed under tongues for rapid absorption, half life of 1-2 hours, onset of action is 5 minutes ...
Other Popular Dietary Supplements
Other Popular Dietary Supplements

... Long used in a manner similar to ginseng, i.e. as a “tonic” and “adaptogen” •Chemistry steroidal glycosides termed eleutherosides are present in the root •Pharmacology animal studies indicate some interesting pharmacological activities. •Use: high or low blood pressure, atherosclerosis, pyelonephrit ...
States of Consciousness
States of Consciousness

... • Suffer from sleeplessness and may fall asleep at unpredictable or inappropriate times. • Directly into REM sleep • Less than .001 % of population. ...
Attention Deficit Hyperactivity Disorder
Attention Deficit Hyperactivity Disorder

... Side Effects of ADHD Drugs • Rarely, medications for ADHD can cause more serious side effects. • For instance, some stimulants are associated with an increased risk of cardiovascular problems and sudden death. • They may also exacerbate psychiatric conditions like depression or anxiety. ...
Mechanism of Actions of Antidepressants: Beyond the Receptors
Mechanism of Actions of Antidepressants: Beyond the Receptors

... little affinity for other neuroreceptors including serotonin, dopamine, histamine, muscarinergic and alpha adrenergic sites. NE depletion studies suggest that while NE reuptake inhibition may improve all core symptoms of depression, NE regulation may be most closely correlated with patient’s improve ...
Restless legs syndrome
Restless legs syndrome

... Drug treatment (about 20% of people need drug treatment). Consider only if non-drug treatment and iron supplements do not improve symptoms. The licenced agents are all non-ergot derived dopamine agonists: ropinirole, pramipexole and rotigotine. There is insufficient evidence to recommend one over an ...
Department of Pharmacology
Department of Pharmacology

... the Final Exam, shall be the basis for calculation the final grade from the pharmacology course, as follows: FINAL grade= final exam grade x 0.6 + seminars mean grade x 0.4  The Final Exam must be passed to qualify for pharmacology course completion.  If a student fails to pass the Final Exam, the ...
File - JALC PSY 132
File - JALC PSY 132

... IX. UPPERS A. Amphetamines – synthetic stimulants  -were once widely prescribed for weight loss or depression; today: narcolepsy, childhood hyperactivity, and overdoses of depressant drugs. ...
Drug Discovery and Development
Drug Discovery and Development

... • Under this law, companies who develop such a drug are entitled to market it without competition for seven years. • This is considered a significant benefit, since the standards for patent protection are much more stringent. ...
Is a Drug Polar or Non-polar (and why does this matter?)
Is a Drug Polar or Non-polar (and why does this matter?)

... Intrathecal Injection •An intrathecal injection (often simply called "intrathecal") is an injection into the spinal canal (intrathecal space surrounding the spinal cord), as in a spinal anaesthesia or in chemotherapy or pain ...
Abstract
Abstract

... the presence of angiotensin II and is reduced in the presence of non-selective AII receptor antagonists that block both AT1 and AT2 receptor subtypes (eg saralasin). AT1-selective antagonists have also been studied in this model, at pharmacologically relevant doses. The AT1 blocker eprosartan reduce ...
Appetite Stimulants - Nicole Parello, Nutritionist
Appetite Stimulants - Nicole Parello, Nutritionist

... more than 12 weeks (Rudolph, 2010); no control studies were done on Dronabinol (Marinol) so should not be recommended (Uptodat, 2013) Some evidence shows Megestrol (Megace) may be of benefit; however its use is not without risks and has not been studied for long term periods of time (greater than 6 ...
Appropriate Drug Prescribing in Older Adults
Appropriate Drug Prescribing in Older Adults

...  23 million prescriptions filled and sales that year of $291 million ...
States of Consciousness PowerPoint
States of Consciousness PowerPoint

... • Suffer from sleeplessness and may fall asleep at unpredictable or inappropriate times. • Directly into REM sleep • Less than .001 % of population. ...
Document
Document

... • Class I: Inhibitors of Na+ influx (voltage sensitive Na)- subdivided into Ia, Ib and Ic • Class II: ß-adrenoceptor antagonists • Class III: Drugs that substantially prolong the cardiac action potential • Class IV: Calcium antagonists ...
PHYS
PHYS

... 2014 study found 10 million people drove in the last year while using illicit drugs1 “A 2010 nationwide study of fatal crashes found:  46.5 % of drivers who tested positive for drugs had used a Rx  The most common prescription drugs found were: drug,  “alprazolam (Xanax®) 12.1%  hydrocodone (Vic ...
Modafinil - North East Sleep Society
Modafinil - North East Sleep Society

... Hanson LR , Taheri M, Kamsheh L, et al. Intranasal administration of hypocretin 1 (orexin A) bypasses the blood-brain barrier and target the brain: a new strategy for the treatment of narcolepsy. . Drug Deliv Tech 2004;4:1-10. Born J, Lange T, Kern W, et al.. Sniffing neuropeptides: a transnasal app ...
Polypharmacy and Medication-Related Challenges in the Geriatric
Polypharmacy and Medication-Related Challenges in the Geriatric

... to ARS—describes anticholinergic and sedative drug burden  Higher DBI associated with reduced physical and cognitive function  Potential to be incorporated into DUR software, but not readily available to most clinicians  Need studies to determine if improving DBI score results in better outcomes ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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