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Positional statement on Diclofenac/ ibuprofen switch
Positional statement on Diclofenac/ ibuprofen switch

... orally, ibuprofen is still first line choice for these patients, however diclofenac (short term and at the lowest possible dose) is second line as it is safer in breast feeding than naproxen. Patients who present with renal colic or renal stones and require admission may be treated with oral diclofe ...
Antiepileptic drugs
Antiepileptic drugs

... mainly by two main mechanisms: ...
07 Rhinitis & cough
07 Rhinitis & cough

... • Common effect; Varies with drugs & with patients • Useful as OTC “sleep aid” medication & unsuitable for daytime use. E.g. promethazine, diphenhydramine, doxylamine & pyrilamine. ...
Mechanisms of Therapeutic Actions and Adverse Side Effects
Mechanisms of Therapeutic Actions and Adverse Side Effects

... All antipsychotics (both conventional and atypical) bind to some degree at dopamine D2 receptors. It is believed that D2 antagonism mediates antipsychotics’ ability to reduce positive symptoms of schizophrenia, including hallucinations and delusions. What sets the atypical antipsychotics apart from ...
Atenolol to bisoprolol conversion
Atenolol to bisoprolol conversion

... Timolol Brevibloc Esmolol Cartrol Carteolol Up-to date list of blood pressure lowering medications by classes, including diuretics, ACE inhibitors, Beta-Blockers, Calcium Channel Blockers, Vasodilators, anti. Bisoprolol official prescribing information for healthcare professionals. Includes: indicat ...
NIDA InfoFacts: Steroids (Anabolic-Androgenic)
NIDA InfoFacts: Steroids (Anabolic-Androgenic)

... acute effects of AAS in the brain are substantially different from those of other drugs of abuse. The most important difference is that AAS are not euphorigenic, meaning they do not trigger rapid increases in the neurotransmitter dopamine, which is responsible for the “high” that often drives substa ...
pharmacokinetics-3
pharmacokinetics-3

... Renal Elimination • Glomerular filtration: molecules below 20 kDa pass into filtrate. Drug must be free, not protein bound. • Tubular secretion/reabsorption: Active transport. Followed by passive & active. DP=D + P. As D transported, shift in equilibrium to release more free D. Drugs with high lipi ...
Epinephrine
Epinephrine

... • primary activity: stimulation of the betaadrenoceptors of the heart –  contractility,  cardiac output ...
The Extent and Implications of Poly
The Extent and Implications of Poly

... The World Health Organisation (WHO) defines poly-drug or multiple drug use as, “The use of more than one drug or type of drug by an individual, often at the same time or sequentially, and usually with the intention of enhancing, potentiating, or counteracting the effects of another drug. The term is ...
Kartong - Farmacie Mondiaal
Kartong - Farmacie Mondiaal

... reorganised in cooperation with the two nurses and a second hand Dutch pharmacy drawer cupboard has been installed and put to use. Visits, talks and discussions to and with people at other healthcare clinics (e.g. The Jammeh Foundation for Peace-hospital in Serrakunda and a German sponsored healthca ...
RIFAMPIN
RIFAMPIN

... and low cost. Also, it achieves a high level in all body cells and fluids. Isoniazid is used alone as chemoprophylaxis in the following cases: 1- Very close contact to recent diagnosed cases. 2- Persons converting from negative to positive tuberculin skin test. ...
Drugs and Toxicology - Ms MacCormack`s Science Classes
Drugs and Toxicology - Ms MacCormack`s Science Classes

... Tetrahydrocannabinol, THC, is the chemical found in marijuana that is responsible for the hallucinogenic effects. Use does not cause physical dependency Heavy, long-term use can lead to psychological dependence. ...
Antiinflammatory Drugs
Antiinflammatory Drugs

... - Celecoxib - Rofecoxib ...
Unit I
Unit I

... Drug-Drug: when one drug increases or decreases the effect of another drug or both drugs. (Enzyme induction or enzyme inhibitor) EX: glyburide and alcohol Effect: acute-inhibition of enzymes-hypoglycemia ...
AntiAngiogenics_LauraRoberts
AntiAngiogenics_LauraRoberts

... • Other beneficial properties include reduction of negative symptoms • This is because serotonin receptors are blocked as well as dopamine receptors ...
(mg/L) x CL
(mg/L) x CL

... of one formulation against a second (reference) formulation given by the same route. ...
Document
Document

... • Relieve itching and swelling associated with uncomplicated allergic skin reactions. ...
antidepressants_and_mode_stabilizing_drugs
antidepressants_and_mode_stabilizing_drugs

... suggests changes that depression due to a adaptive (but not theisprimary drug deficiency of monoamines in effect) are responsible at forcertain the sites clinical improvement. the brain, while mania is caused by an overproduction of these neurotransmitters. ...
heart failure
heart failure

...  B-blockers give protection against catecholamine myocyte toxicity.  we should start slowly& then up titrate gradually &watching adverse effects.  B-blockers add only to existing therapy include ACEI &diuretic &(in some studies) digoxin & idealy not ...
T 1/2
T 1/2

... 4 Excretion of drugs drugs are eliminated from the body either unchanged or as metablites. Excretory organs, the lung excluded, eliminate polar compounds more efficiently than substances with high lipid solubility. The kidney is the most important organ for elimination of drugs and their metaboli ...
Pharmacology of the autonomic nervous system for dental students
Pharmacology of the autonomic nervous system for dental students

... A β receptor blockers produce negative cardiac effects (negative chrono-, dromo-, inotropic effects). Accordingly, tachycardia and hypertension (’minute volume’ hypertension) are the main indications. β receptor blocking drugs are also used in angina pectoris (decrease the oxygen demand of the heart ...
Genetic identification of AChE as a positive modulator of addiction to
Genetic identification of AChE as a positive modulator of addiction to

... Received 28 July 2005; accepted 12 October 2005 ...
Day 1- Resting Heart Rate/Recovery Heart Rate/Training Heart Rate
Day 1- Resting Heart Rate/Recovery Heart Rate/Training Heart Rate

... often is seen when the drugs are stopped and may contribute to dependence on anabolic steroids. Researchers report also that users may suffer from paranoid jealousy, extreme irritability, delusions, and impaired judgment stemming from feelings of invincibility. Day 7 –Creatine Creatine is a combinat ...
Clinical Toolkit Benzodiazepines: Use and Taper
Clinical Toolkit Benzodiazepines: Use and Taper

... medical/nonmedical abuse prior to prescribing in all patients. Red-Flags for Abuse or Addiction include: ...
Social brains on drugs: tools for neuromodulation
Social brains on drugs: tools for neuromodulation

... prefrontal cortex (Hall et al., 1994). The consequence of this neuronal architecture is that neuromodulators, when released, can have different effects in different brain regions according to the type of receptor activated. Some pharmacological agents directly stimulate or block neuromodulator recep ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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