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Slide 1
Slide 1

... Delafuente J. Understanding and preventing drug interactions in elderly patients. Critical Reviews in Oncology/Hematology 2003; 48: 133-143. Gurwitz J, Field T, et al. Incidence and Preventability of Adverse Drug Events Among Older Persons in the ...
FREE Sample Here - We can offer most test bank and
FREE Sample Here - We can offer most test bank and

... The liver and kidneys are the organs that are most important for drug metabolism and elimination. A problem that decreases the function of either organ increases active blood drug levels and the length of time a single drug dose remains in the body. Both conditions lead to an increased risk for drug ...
What Clinicians Need to Know - AIDS Education and Training Centers
What Clinicians Need to Know - AIDS Education and Training Centers

...  This compared to 2.1% (95% CI=1.3-2.9) for 2701 nondrug using MSM tested in the same sites ...
Alcoholism and Benzodiazepines
Alcoholism and Benzodiazepines

... Alcohol abuse is the third leading cause of preventable death and is associated with 100,000 deaths per year. Chronic alcohol abuse is also common in hospitalized patients. Among all elderly patients admitted to general hospitals in the United States, 20% to 40% will have alcohol-related disorders; ...
The Medical Letter
The Medical Letter

... Pregnancy – Topiramate has been associated with a 2to 5-fold increased risk of oral clefts when taken in the first trimester of pregnancy. Qsymia is contraindicated for use during pregnancy and is available only through a restricted access program (Qsymia REMS) designed to prevent fetal exposure to ...
Suggestion from clinicians
Suggestion from clinicians

... and that incomplete reporting still makes it difficult for anyone to draw clear conclusions on the comparative effects of these drugs. However, it seems that haloperidol causes more movement disorders than chlorpromazine, while chlorpromazine is significantly more likely to lead to hypotonia. We are ...
in the elderly
in the elderly

... • Chronic diseases requiring long-term treatment become more common. • Atypical presentation of diseases. • Expectations of both the family and the patient (people keep going to see the doctor until they get what they want). • There is no satisfactory doctor-patient relationship in time or in depth ...
antihistamines
antihistamines

... The future of antihistamines • The anti-inflammatory activity of second generation antihistamines, about which little is known, will continue to be researched and possibly lead to an effective alternative to corticosteriods in the treatment of allergic airways conditions. • The action of the H4 rec ...
Antimalarial Drugs
Antimalarial Drugs

... Excretion Infos  Derived from Chinese herbs  Half life of 1-3 hours after oral admin o Artemisia annua  Excreted primarily  Used as antipyretic in the through urine ancient China  Rapidly acting blood schizonticide  Higher sensitivity to Chloroquine-resistant parasite  10-100 times more poten ...
Psychostimulants - Western Australian Therapeutics Advisory Group
Psychostimulants - Western Australian Therapeutics Advisory Group

... Gamma hydroxybutyrate, also known as GHB or sodium oxybate, is an approved treatment for excessive daytime sleepiness and cataplexy associated with narcolepsy in some countries including the United States.15 It promotes wakefulness due to its CNS depressant actions17 on slow-wave sleep, making the p ...
Acids, bases and cocaine addicts
Acids, bases and cocaine addicts

... Research in the fields of drug abuse, pharmacology and psychology indicates that the period of time between the introduction of a drug into the body and its ability to produce euphoria or pleasure is important in the abuse potential of that drug. Cocaine produces its high within seconds when smoked ...
GeriPharmacology_final 4472KB Feb 23 2016 09:38:36 PM
GeriPharmacology_final 4472KB Feb 23 2016 09:38:36 PM

... Gallagher P, O’Mahony D. STOPP (Screening Tool of Older Persons’ potentially inappropriate Prescriptions): application to acutely ill elderly patients and comparison with Beers’ criteria. Age Ageing 2008;37:673-9. Barry PJ, Gallagher P, Ryan C, O’Mahony D. START (screening tool to alert doctors to t ...
Smoking
Smoking

... Smoke affects all people who are exposed to it, but the degree and severity is modified by many susceptibility determinants.(Martin et al2009) ...
Evaluating Hallucinogenic or Psychedelic Drug Intoxication in an
Evaluating Hallucinogenic or Psychedelic Drug Intoxication in an

... metabolite of THC is 11-hydroxy THC; the pri- disappear during infancy and reappear later in mary inactive metabolite is THC carboxylic acid early childhood.24 (Fig 3). Although the plant contains about 60 other resins called cannabinoids, these substances Diagnosis of have very little if any psycho ...
Bedside Teaching Triggers
Bedside Teaching Triggers

... decrease and so does Vd. ii.The decrease in serum albumin seen with aging is usually secondary to disease. Acute phase reactant decreases in albumin are also partially counterbalanced by -1 acid glycoprotein; so total protein binding is not usually effected in the elderly. Aging and digoxin: i. Dig ...
Bedside Teaching Trigger
Bedside Teaching Trigger

... decrease and so does Vd. ii.The decrease in serum albumin seen with aging is usually secondary to disease. Acute phase reactant decreases in albumin are also partially counterbalanced by -1 acid glycoprotein; so total protein binding is not usually effected in the elderly. Aging and digoxin: i. Dig ...
Solutions: October 2011: Addiction by Prescription — For All Ages
Solutions: October 2011: Addiction by Prescription — For All Ages

... Narcotic analgesics. Narcotic analgesics are prescribed because of their pain-relieving properties. Medications that fall within this class include morphine, demerol, codeine and their closely related synthetic cousins. Morphine, one of the most powerful pain relievers available, is used to treat se ...
Intrathecal adjuvants MGMC
Intrathecal adjuvants MGMC

... were compared for vaginal surgeries with bupivacaine anesthesia. • Dexmedetomidine caused significantly longer sensory ...
April 2017
April 2017

... Addiction is also defined many ways. The American Society of Addiction Medicine (ASAM) defines addiction as a primary, chronic, neurobiologic disease of brain motivation, reward, and memory with genetic, psychosocial, and environmental factors influencing its development and manifestations. The Amer ...
1 - Yimg
1 - Yimg

... Hemostasis : 5-HT2 receptors → aggregation and vasoconstriction of platelets • Carcinoid syndrome (tumor of serotonin producing cells) large amounts released leading to diarrhea, bronchoconstriction and edema ...
(Agonist) of Nuclear Receptor
(Agonist) of Nuclear Receptor

... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
Pharmacodynamics
Pharmacodynamics

... AIDS PATIENT-DOCTOR RELATIONSHIP: The patient has more respect for and trust in a therapist who can convey to the patient how the drug is affecting the patient’s body. A patient who understands his/her therapy is more inclined to become an active participant in the management of the patient’s diseas ...
Carbamazepine: Watch for Many Potential Drug Interactions
Carbamazepine: Watch for Many Potential Drug Interactions

... discontinued, the induction will slowly dissipate, and the metabolism of the object drug will return to normal. If the dose of the object drug is not reduced, toxicity may occur. Carbamazepine is an inducer of several potential pathways of drug elimination, including CYPs 1A2, 2C9, and 3A4, as well ...
heart failure pharma team girls - Copy
heart failure pharma team girls - Copy

... Drugs with + inotropic action: *  Agonist: ...
Opioids OD fact sheet
Opioids OD fact sheet

... Heroin: crosses BBB; very short DOA (peak 3mins; last few hours); can cause NCPO (immediately or delayed 24hrs); symptoms <6hr; 60% OD deaths occur in company of others; 15% deaths are sudden death after injecting; ambulance called in only 10% fatal cases; no intervention prior to death in 80% Oxyco ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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