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Executive Director Hunterdon Drug Awareness Program, Inc.
Executive Director Hunterdon Drug Awareness Program, Inc.

... Because of the emerging nature of these drugs, most specifically MDPV to the US marketplace, there seems to be confusion regarding MDPV and other drugs such as Mephedrone (4-MMC) being used in bath salts. Mephedrone, also known as 4-methylmethcathinone (4-MMC), or 4methylephedrone, is a synthetic st ...
Respiratory-pharmacology
Respiratory-pharmacology

... Loading dose of 6 mg/kg IV infusion over 20 minutes Loading dose of 1 mg/kg IV infusion over 20 minutes if the patient has had theophylline products in the last 35 ...
Determining the subjective and physiological effects
Determining the subjective and physiological effects

... 250 mg with one preparation offering 500 mg per dose. In New Zealand, party pills were marketed under many brand names and were readily available from a variety of sources such as specific party pill shops and liquor stores in addition to being widely sold over the Internet. BZP and related compound ...
Anxiety Disorders Formulary Guidance [v1.1]
Anxiety Disorders Formulary Guidance [v1.1]

...  Use low initial doses of antidepressant and titrate up slowly, Higher doses may be necessary if standard doses are ineffective.  There may be an initial exacerbation of anxiety and panic symptoms.  It can take several weeks before the effects of antidepressants are evident.  When new medication ...
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... • Mechanism of action unclear but may inhibit cyclooxygenase in the CNS • Acetaminophen can cause liver damage if dose exceeds 4 grams a day • Risk of hepatic injury is increased in patients having pre-existing liver damage (alcoholism, hepatitis) • Acetaminophen has also been shown to cause renal d ...
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... formation in uveitis (inflammation of the middle layer of the eye ) and iritis. The longer-lasting preparations, especially homatropine, are valuable for this indication ...
(neuroleptics, tranquillisers, sedative, lithium salts)
(neuroleptics, tranquillisers, sedative, lithium salts)

... tioxanten, butyrophenon – they cause disorders of extrapyramidal system function ...
Nasalox Insert
Nasalox Insert

... If a dose missed then take it as soon as possible. However, if it is almost time for next dose, skip the missed dose and go back to regular dosing schedule. Do not take double doses. Contraindications Contraindicated in patients with hypersensivity to Oxymetazoline Hydrochloride. Side Effects When t ...
SuperTarget goes quantitative: update on drug–target interactions
SuperTarget goes quantitative: update on drug–target interactions

... inhibitors of VEGFR-2, which do not affect the other receptor subtype VEGFR-1. A general idea about the specificity of an inhibitor is provided by its IC50 value. This refers to the compound concentration, which is needed for a half-maximum inhibition of the corresponding biological process. Thus, po ...
Hallucinogenic Drugs
Hallucinogenic Drugs

... mushrooms first appear in recorded history when European explorers came into contact with Central American tribes in the sixteenth century. In their writings there is the description of participants at the coronation of Montezuma II consuming ‘inebriating mushrooms’ and having heavenly visions. These ...


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A 35 Year-Old Woman with Spontaneous Iliac Artery Rupture
A 35 Year-Old Woman with Spontaneous Iliac Artery Rupture

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Perphenazine Fact Sheet - The Main Line Center for the Family
Perphenazine Fact Sheet - The Main Line Center for the Family

... Perphenazine may enhance ultraviolet light absorption in the skin—a reaction known as photosensitivity—and predispose the person to sunburn. Patients should avoid prolonged exposure to sunlight, use sunscreen, and wear protective clothing until tolerance is developed to the medication. Under very ho ...
OTC Drugs Monograph - Thai Self Medication Industry Association
OTC Drugs Monograph - Thai Self Medication Industry Association

... Over-the-Counter Drugs(1)  Used by the public as self-medication  Properly decided by the public on selection of indication, dose, compliance with dose, prevention of side effects, or treatment • Dosage forms that have high possibility of misuse and abuse, or of less or no safety and efficacy unl ...
Pain and Progress: Is it Possible to Make a Nonaddictive Opioid
Pain and Progress: Is it Possible to Make a Nonaddictive Opioid

... Why start from scratch? Some companies are reformulating approved drugs to make them more difficult to snort and inject. Recognizing that getting a new medication on the market is a monumental and expensive task, some pain researchers argue that a more promising solution to the opioid problem is to ...
Consciousness - Ashton Southard
Consciousness - Ashton Southard

... stimulants and memory-enhancing drugs to boost cognitive performance in adults  But the most common altered state people experience is sleep ...
Adverse Drug Reactions to Antibiotics and Major Antibiotic Drug
Adverse Drug Reactions to Antibiotics and Major Antibiotic Drug

... of pharmacotherapy A thorough knowledge of how the adverse reactions and drug in­ teractions occur will aid in our ability to provide the best patient care possible Adverse drug reactions and drug interactions are defined and mechanisms of their occurrence are discussed, ways to identify, assess, ma ...
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... Typical diseases The search for pharmaceutical drugs used to be rather straight forward until recent times: A wealth of information about the disease, its causes, and the clinical symptoms were readily available. Thus the starting point for the pharmacological therapy was known. Example: inhibition ...
EFFECTS OF COFFEE ON THE CENTRAL NERVOUS SYSTEM
EFFECTS OF COFFEE ON THE CENTRAL NERVOUS SYSTEM

... Avicenne, an Arab living in the 11 century. Then, Prosper Albin, an Italian botanist and medical doctor studied coffee during a trip to Egypt in 1580 and mentioned that .Arabs and Egyptians use it to make a kind of infusion that is popular and that they drink in place of wine.. The first citations o ...
Characterization of the Effects of the Partial Dopamine Agonist
Characterization of the Effects of the Partial Dopamine Agonist

... Latin-square design. The drug was prepared in a vehicle solution of 0.9% physiological saline with a drop of 1 N HCl and injected in a volume of 1.0 ml/kg of body weight. At least two days of baseline self-administration separated drug testing days. The total number of reinforcers earned during the ...
Information Sheet AMT - Scottish Drugs Forum
Information Sheet AMT - Scottish Drugs Forum

... orally, it is not uncommon for users to re-dose in error thinking they have not taken enough initially. Users generally advise waiting at least 2.5 hours before re-dosing to avoid unwanted effects, or over-dosing. When smoked, the onset is significantly quicker at 10-30 seconds with typical duration ...
Inappropriate Drug Use in the Elderly
Inappropriate Drug Use in the Elderly

... James W. Cooper, RPh, PhD, BCPS, CGP, FASCP, FASHP, Emeritus Professor of Pharmacy Care and Consultant Pharmacist, College of Pharmacy, University of Georgia, ...
Medications Used to Treat Restless Legs Syndrome
Medications Used to Treat Restless Legs Syndrome

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PRINCIBLES OF DRUG USE İN PREGNANCY
PRINCIBLES OF DRUG USE İN PREGNANCY

... to improper technique and/or activity of inhibitors such as dopamine. ...
PHL 313 practical
PHL 313 practical

... • Catecholamines have a half- life of a few minutes when circulating in blood. • They are degraded by COMT or MAO. • Amphetamines and MAOIs bind to MAO in order to inhibit its action of breaking down catecholamines. • This is the primary reason why the effects of amphetamines have a longer lifspan t ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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