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adderall xr - Shire Canada
adderall xr - Shire Canada

... heart problems. Although some serious heart problems alone carry an increased risk of sudden death, ADDERALL XR (mixed salts amphetamine extended-release capsules) generally should not be used in children/adolescents with known serious structural cardiac abnormalities or other serious heart problems ...
Eltor (pseudoephedrine hydrochloride)
Eltor (pseudoephedrine hydrochloride)

... In the anesthetized dog, Patil et al,4 found that pseudoephedrine possessed only 20% of the relative pressor potency of ephedrine although the duration of blood pressure elevation was approximately doubled. An increase in heart rate paralleled these blood pressure effects. The rate of development of ...
Chapter 34 Antihypertension Drugs
Chapter 34 Antihypertension Drugs

... the patient, the severity of organ damage (if any) due to high blood pressure, and the presence of cardiovascular risk factors must all be considered. ------Begin the drug treatment or not. ...
307.
307.

... 3 of the most commonly prescribed PIMs (opioids, antidepressants, and orthostatic drugs) were often appropriate for condition Risk factors for PIMs did not predict AIMs We should (move beyond) labeling medicines as ...
酸枣仁油软胶囊的新药开发研究
酸枣仁油软胶囊的新药开发研究

... Symptomatic treatment remission of symptoms or suffering of disease. (for instance, analgesia, sedation…) ...
3/2009 - Repatriation Medical Authority
3/2009 - Repatriation Medical Authority

... "death from drug dependence or drug abuse" in relation to a person includes death from a terminal event or condition that was contributed to by the person’s drug dependence or drug abuse; "drug" (as referred to in the definition of "drug dependence" or "drug abuse" and as derived from DSM-IV-TR) mea ...
Calculating equivalent doses of oral benzodiazepines
Calculating equivalent doses of oral benzodiazepines

... Switching benzodiazepines may be advantageous for a variety of reasons, e.g. to a drug with a different half-life pre-discontinuation (4) or in the event of non-availability of a specific benzodiazepine. With relatively short-acting benzodiazepines such as alprazolam and lorazepam, it is not possibl ...
Therapeutic applications of ricin and some alkaloids
Therapeutic applications of ricin and some alkaloids

... cells within a tumor. Engert and Thorpe [7] prepared immunotoxins by linking ricin A-chain to several moAbs that recognize different markers on Hodgkin/Reed-Sternberg (H-RS) cells, tested their antitumor activity successfully in vitro and also in mice Hodgkin’s tumor models. Therefore, they advocate ...
Putting it all together
Putting it all together

... • In addition to reducing inflammation, glucocorticosteroids decrease airway mucus production, increase the number of bronchial b2 receptors and their responsiveness to b2 agonists ...
Pediatric Psychopharmacology
Pediatric Psychopharmacology

... Remember, most meds are reversibly bound to albumin, and only the free unbound portion is active and available for tissue distribution. different sites for acidic drugs (globulin) and basic drugs (a-1 glycoprotein) b/c a-1 glycoprotein is an acute phase reactant, its increased presence during inf ...
VISTARIL® (hydroxyzine pamoate) Capsules and Oral
VISTARIL® (hydroxyzine pamoate) Capsules and Oral

... atopic and contact dermatoses, and in histamine-mediated pruritus: in adults, 25 mg t.i.d. or q.i.d.; children under 6 years, 50 mg daily in divided doses; and over 6 years, 50-100 mg daily in ...
Neurochemical Neutralization of Methamphetamine With High
Neurochemical Neutralization of Methamphetamine With High

... The major finding reported here is that indatraline, a reuptake inhibitor with high affinity for NE, DA, and 5-HT transporters (Hyttel and Larsen, 1985), blocks the ability of METH and MDMA to release these neurotransmitters. The results demonstrate that an indatraline, or a similarly acting agent, ...
Drug abuse and kidney
Drug abuse and kidney

... among intravenous users has been described47. This is explained by the improvement of the quality of heroin supplied to addicts, thus exposed to lower doses of potentially nephrotoxic additional substances. Nowadays, nephropathy associated with the virus HIV (HIVAN) is diagnosed more frequently in h ...
Becoming Neurochemical Selves
Becoming Neurochemical Selves

... psychiatric conditions. It is well known that the first widely used psychiatric drug was chlorpromazine, developed from antihistamines by company scientists at the pharmaceutical firm Rhône-Poulenc in the years after the Second World War.2 Two French psychiatrists, Pierre Deniker and Jean Delay, who ...
Side effects
Side effects

... Antitubercular drugs. ...
CLINICAL PHARMACOLOGY Dr. P. Oh Aman Hussain, chapter editor
CLINICAL PHARMACOLOGY Dr. P. Oh Aman Hussain, chapter editor

... • only free drug can distribute into tissues and exert its action, and is subject to metabolism and elimination • affinity of a protein binding site for a drug determines bound/unbound concentrations, and reversibility of interaction • saturation of binding sites may result in a large increase in un ...
Factors affecting drug metabolism
Factors affecting drug metabolism

...  Physiologic factors: including age, hormonal changes, sex differences, pregnancy and nutritional status.  Pharmacodynamic factors: including dose, frequency, route of administration and protein binding.  Environmental factors: this depends on the competition with other drugs for the metabolizing ...
Antidepressants /Antiepileptic drugs
Antidepressants /Antiepileptic drugs

... inhibition of norepinephrine reuptake. Tertiary amines such as amitriptyline and imipramine show more balanced inhibition of norepinephrine and serotonin, but they also have greater anticholinergic side effects. The novel antidepressants venlafaxine and duloxetine have balanced inhibition of seroton ...
Focalin XR
Focalin XR

... with structural cardiac abnormalities or other serious heart problems. Although some serious heart problems alone carry an increased risk of sudden death, stimulant products generally should not be used in children or adolescents with known serious structural cardiac abnormalities, cardiomyopathy, s ...
Pharmacological Treatment of Dependence
Pharmacological Treatment of Dependence

... -Palpitations ...
PDF full-Text - Journal of Investigational Allergology and Clinical
PDF full-Text - Journal of Investigational Allergology and Clinical

... In this sense, there are many studies favourable to all the 2nd generation AH of systemic use [17], using various classic AH as active comparators. The European Union requires medicines marketed in the member countries to be classiÀed in three categories according to their capacity to affect the dri ...
A Review on Benzylpiperazine and Trifluoromethylphenypiperazine
A Review on Benzylpiperazine and Trifluoromethylphenypiperazine

... drugs as more of a cocktail, with TFMPP as the minor component, in a common ratio of 2:1, even though other ratios of combination are mentioned in uncertified sources. A combination of BZP and TFMPP is always advertised as a MDMA substitute, due to the similar effects on the serotonin system, whereb ...
Appendix C: First-Line Antidepressants
Appendix C: First-Line Antidepressants

... Sexual disturbances: libido, impotence, ejaculatory disturbances, anorgasmia. (likely to persist during SSRI therapy) Hyponatremia: can occur. (may cause fatigue or delirium) Serotonin Syndrome: agitation, tachycardia, tremor hyperreflexia. (combination with other serotonergic dugs also increase ris ...
Lecture. PSYCHOTROPIC DRUGS I. NEUROLEPTICS
Lecture. PSYCHOTROPIC DRUGS I. NEUROLEPTICS

... administration develops in 30-90 min; elimination is characterized by two phases (the 1st short phase with distribution of the drug in tissues during 3 hrs and the 2nd long-lasting phase with T½= 48 hrs); is more active than clordiazepoxide, especially in anti-seizure effect; causes decrease in nigh ...
Adrenergic_antagonis..
Adrenergic_antagonis..

... It freely passes BBB & reaches CNS then it is converted to α– methylenorepinephrine which acts as an agonist at central α2 – adrenoreceptors. ...
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Stimulant



Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.
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