Adrenergic_antagonis..
... It freely passes BBB & reaches CNS then it is converted to α– methylenorepinephrine which acts as an agonist at central α2 – adrenoreceptors. ...
... It freely passes BBB & reaches CNS then it is converted to α– methylenorepinephrine which acts as an agonist at central α2 – adrenoreceptors. ...
THE CHIRAL SWITCH: THE DEVELOPMENT OF SINGLE
... Obviously potential difficulties may arise if the sponsor of the single enantiomer was not responsible for the original submission [25]. These investigations should include a comparison of the pharmacokinetic profile of the single enantiomer following administration as such and as a component of the ...
... Obviously potential difficulties may arise if the sponsor of the single enantiomer was not responsible for the original submission [25]. These investigations should include a comparison of the pharmacokinetic profile of the single enantiomer following administration as such and as a component of the ...
Drug Tolerance
... Cannabis sativa – common hemp plant THC – primary psychoactive constituent – although over 80 others are present Endogenous transmitter is anandamide High doses impair short-term memory and interfere with tasks involving multiple steps Addiction potential is low Negative effects of long-term use are ...
... Cannabis sativa – common hemp plant THC – primary psychoactive constituent – although over 80 others are present Endogenous transmitter is anandamide High doses impair short-term memory and interfere with tasks involving multiple steps Addiction potential is low Negative effects of long-term use are ...
Ganglionic Blocking Drugs and Nicotine
... produced by ganglionic blocking drugs depends largely on the quantity and relative proportion of the total autonomic input coming from sympathetic and parasympathetic nerves at the time of drug administration (Table 14.2). For example, if cardiac vagal tone is high at the time ganglion blockade is i ...
... produced by ganglionic blocking drugs depends largely on the quantity and relative proportion of the total autonomic input coming from sympathetic and parasympathetic nerves at the time of drug administration (Table 14.2). For example, if cardiac vagal tone is high at the time ganglion blockade is i ...
Anticholinergic drugs used in Parkinson`s disease: An
... 1 in 1000 people (1). It has been estimated that in persons aged 65 years and older, the incidence is approximately 1% (2). From a biochemical perspective, Parkinson's is thought to be caused by degeneration of dopaminergic neurons in the neostriatum, a region of the basal ganglia in the brain impor ...
... 1 in 1000 people (1). It has been estimated that in persons aged 65 years and older, the incidence is approximately 1% (2). From a biochemical perspective, Parkinson's is thought to be caused by degeneration of dopaminergic neurons in the neostriatum, a region of the basal ganglia in the brain impor ...
Panic Disorder
... symptoms of peripheral autonomic hyperactivity including: Tremulousness, palpitations, and hyperventilation According to the noradrenergic model: The autonomic nervous system of patients with anxiety disorders becomes oversensitive to various stimuli, responding with: ...
... symptoms of peripheral autonomic hyperactivity including: Tremulousness, palpitations, and hyperventilation According to the noradrenergic model: The autonomic nervous system of patients with anxiety disorders becomes oversensitive to various stimuli, responding with: ...
THE EFFECTS OF CAFFEINE AND PIRACETAM ON Mus musculus
... metabolism throughout the brain, but at the same time decreases cerebral blood flow, which results in a relative state of brain hypoperfusion. Caffeine also activates noradrenaline neurons and seems to affect the local release of dopamine, which may have a minor stimulatory effect, but not likely en ...
... metabolism throughout the brain, but at the same time decreases cerebral blood flow, which results in a relative state of brain hypoperfusion. Caffeine also activates noradrenaline neurons and seems to affect the local release of dopamine, which may have a minor stimulatory effect, but not likely en ...
HIVTRI workshop: Treatment information for doctors and
... • timeline for newer drugs • timeline for new strategies ...
... • timeline for newer drugs • timeline for new strategies ...
Document
... introduced into or absorbed by a living organism. • Scientifically, a poison is any substance taken into the body by ingestion, inhalation, injection, or absorption that interferes with normal physiological functions. • Virtually any substance can be poisonous if consumed in sufficient quantity; the ...
... introduced into or absorbed by a living organism. • Scientifically, a poison is any substance taken into the body by ingestion, inhalation, injection, or absorption that interferes with normal physiological functions. • Virtually any substance can be poisonous if consumed in sufficient quantity; the ...
Slide 1
... • Most of the actions of GH are mediated by IGF-1 ( insulinlike growth factor 1) “somatomedins” - the peptides produced in the liver and cartilage. • The somatomedins stimulate skeletal growth, amino acid transport, protein synthesis, nucleic acid synthesis and cell proliferation. ...
... • Most of the actions of GH are mediated by IGF-1 ( insulinlike growth factor 1) “somatomedins” - the peptides produced in the liver and cartilage. • The somatomedins stimulate skeletal growth, amino acid transport, protein synthesis, nucleic acid synthesis and cell proliferation. ...
Anabolic_Steroids-2
... body and cover multiple body systems. • The chemicals added to steroid derivatives may be to blame for the majority of the health side effects. • The dose and how often it is taken (stacking, pyramid) can lead to more extreme side effects or even possible long term effects. ...
... body and cover multiple body systems. • The chemicals added to steroid derivatives may be to blame for the majority of the health side effects. • The dose and how often it is taken (stacking, pyramid) can lead to more extreme side effects or even possible long term effects. ...
Cathartics/purgatives
... Diphenylyl methane Derivatives: Bisacodyl: Mechanism of Action: This agent is hydrolyzed in gut through deacetylation and converted to active form which produces low grade inflammation as a result of which motility and secretions are increased. Adverse Effects: Abdominal pain/discomfort, few allerg ...
... Diphenylyl methane Derivatives: Bisacodyl: Mechanism of Action: This agent is hydrolyzed in gut through deacetylation and converted to active form which produces low grade inflammation as a result of which motility and secretions are increased. Adverse Effects: Abdominal pain/discomfort, few allerg ...
Drug Excretion and Clearance
... GFR is reduced in : newborns, the elderly, patients with kidney and heart disease. Reduced GFR: lower drug dose, increase dose interval or both. ...
... GFR is reduced in : newborns, the elderly, patients with kidney and heart disease. Reduced GFR: lower drug dose, increase dose interval or both. ...
Chapter 5 Drug Toxicity
... changes in receptor number). All such changes can lead to an increase in the effective concentration of the drug and thus to an increased biological response. An important class of on-target adverse effects may occur because the drug, or one of its metabolites, interacts with the appropriate recepto ...
... changes in receptor number). All such changes can lead to an increase in the effective concentration of the drug and thus to an increased biological response. An important class of on-target adverse effects may occur because the drug, or one of its metabolites, interacts with the appropriate recepto ...
The amino acid Tyrosine
... pseudoephedrine are banned from the Sport activities ,classified as a Doping agent (The use of performance-enhancing drugs in human sport is commonly referred to by the term doping ) In fact, until the late 70's ,ephedra preparations were widely used in weightreducing tablets;due to their activity o ...
... pseudoephedrine are banned from the Sport activities ,classified as a Doping agent (The use of performance-enhancing drugs in human sport is commonly referred to by the term doping ) In fact, until the late 70's ,ephedra preparations were widely used in weightreducing tablets;due to their activity o ...
Study of the Side effects profile of different antihypertensive drugs
... fact that the patients attending outpatient department are mostly due to problems related with either uncontrolled blood pressure or side effects of drugs. The side effects experienced with atenolol were bradycardia (14.3%, n=1), palpitation (14.3%, n=1) and insomnia (14.3%, n=1).Atenolol is a cardi ...
... fact that the patients attending outpatient department are mostly due to problems related with either uncontrolled blood pressure or side effects of drugs. The side effects experienced with atenolol were bradycardia (14.3%, n=1), palpitation (14.3%, n=1) and insomnia (14.3%, n=1).Atenolol is a cardi ...
The Nursing Process and Drug Therapy
... lists two antiepileptic medications that are due at 0900, but the patient is NPO for a barium study. The nurse’s coworker suggests giving the medications via IV because the patient is NPO. What should the nurse do? 1. Give the medications PO with a small sip of water. 2. Give the medications via the ...
... lists two antiepileptic medications that are due at 0900, but the patient is NPO for a barium study. The nurse’s coworker suggests giving the medications via IV because the patient is NPO. What should the nurse do? 1. Give the medications PO with a small sip of water. 2. Give the medications via the ...
Adverse Effects
... • They also have the potential for more complete inhibition of angiotensin action compared with ACE inhibitors because there are enzymes other than ACE that are capable of generating angiotenin II. The adverse effects are similar to those described for ACE inhibitors, including the hazard of use du ...
... • They also have the potential for more complete inhibition of angiotensin action compared with ACE inhibitors because there are enzymes other than ACE that are capable of generating angiotenin II. The adverse effects are similar to those described for ACE inhibitors, including the hazard of use du ...
antidepressant activity of methanolic extract of passiflora foetida
... Though several drugs are available, all are associated with some limitations and there is an urgent need for alternative medications for these disorders. Despite the widely popular use of Passiflora foetida for treating nervous disorders, there is an absence of ...
... Though several drugs are available, all are associated with some limitations and there is an urgent need for alternative medications for these disorders. Despite the widely popular use of Passiflora foetida for treating nervous disorders, there is an absence of ...
Opioid Pharmacology
... With continued use, progressively more and more opioid is necessary to produce the same effect ...
... With continued use, progressively more and more opioid is necessary to produce the same effect ...
Griffin 460 Mobile GC/MS Analysis of Designer
... products have been linked to hospitalizations, episodes of psychotic behavior, seizures, death, and long term psychosis in the case of bath salts. In an effort to subvert drug laws, laboratories have developed new classes of research chemicals that bear resemblance to hallucinogens and stimulants. T ...
... products have been linked to hospitalizations, episodes of psychotic behavior, seizures, death, and long term psychosis in the case of bath salts. In an effort to subvert drug laws, laboratories have developed new classes of research chemicals that bear resemblance to hallucinogens and stimulants. T ...
IBS
... standard doses. Higher doses have central opioid actions. Used in combination with a sub-therapeutic dose of atropine (to prevent abuse) Contraindications: 1. Children below 2 y (toxicity at lower doses than adults) 2. Obstructive jaundice ...
... standard doses. Higher doses have central opioid actions. Used in combination with a sub-therapeutic dose of atropine (to prevent abuse) Contraindications: 1. Children below 2 y (toxicity at lower doses than adults) 2. Obstructive jaundice ...
OraLine IV sat - American Screening Corp
... In drug analysis, oral fluid drug screening has certain advantages over the screening of other biological fluids such as urine and blood. Oral fluid is readily accessible, and is less likely to be adulterated. With oral fluid tests, the drugs may be detected immediately after ingestion, even before ...
... In drug analysis, oral fluid drug screening has certain advantages over the screening of other biological fluids such as urine and blood. Oral fluid is readily accessible, and is less likely to be adulterated. With oral fluid tests, the drugs may be detected immediately after ingestion, even before ...
File
... – Therapeutic Effect: action for which the drug is prescribed – Local Effect: confined to a specific part of the body – Systemic Effect: generalized, allinclusive effect on entire body ...
... – Therapeutic Effect: action for which the drug is prescribed – Local Effect: confined to a specific part of the body – Systemic Effect: generalized, allinclusive effect on entire body ...
Stimulant
Stimulants (also referred to as psychostimulants) are psychoactive drugs that induce temporary improvements in either mental or physical functions or both. Examples of these kinds of effects may include enhanced alertness, wakefulness, and locomotion, among others. Due to their rendering a characteristic ""up"" feeling, stimulants are also occasionally referred to as ""uppers"". Depressants or ""downers"", which decrease mental and/or physical function, are in stark contrast to stimulants and are considered to be their functional opposites. Stimulants are widely used throughout the world as prescription medicines and without prescription both as legal substances and illicit substances of recreational use or abuse.