Future Development Plan - sun pharma advanced research company
... © 2011 - Sun Pharma Advanced Research Company Limited (SPARC). All Rights Reserved ...
... © 2011 - Sun Pharma Advanced Research Company Limited (SPARC). All Rights Reserved ...
Discovery Labs Presents Surfaxin and Aerosurf
... are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These forwardlooking statements are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made. Among the factors which could affect ...
... are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These forwardlooking statements are subject to certain risks and uncertainties that could cause actual results to differ materially from the statements made. Among the factors which could affect ...
Drugs that affect the fetus and newborn infant via the placenta or
... during pregnancy can cross the placenta and reach the fetus. Whether knowingly or not, a mother is exposed to several drugs during pregnancy; the number can range from one to as many as six to eight drugs [6 – 8]. The drugs can be prescribed, obtained over the counter, or obtained illicitly (eg, dru ...
... during pregnancy can cross the placenta and reach the fetus. Whether knowingly or not, a mother is exposed to several drugs during pregnancy; the number can range from one to as many as six to eight drugs [6 – 8]. The drugs can be prescribed, obtained over the counter, or obtained illicitly (eg, dru ...
Psychometric assessment of the Hallucinogen Rating Scale Drug Alcohol Depend 137
... elicited by these agents. In this context, new psychometric research tools have been designed to quantify their effects on the central nervous system. By measuring the mood-, perception- and cognition-altering effects that are characteristic of a given drug, these instruments can help characterize t ...
... elicited by these agents. In this context, new psychometric research tools have been designed to quantify their effects on the central nervous system. By measuring the mood-, perception- and cognition-altering effects that are characteristic of a given drug, these instruments can help characterize t ...
Basics of HIV Resistance and Testing
... interactions between mutations Equivalent virologic outcomes in clinical trials to conventional phenotyping Available from many reference labs Rapid turnaround ...
... interactions between mutations Equivalent virologic outcomes in clinical trials to conventional phenotyping Available from many reference labs Rapid turnaround ...
Glyceryl trinitrate - Queensland Ambulance Service
... Service (‘QAS’) Clinical practice manual (‘CPM’) without the priorwritten permission of the Commissioner. The QAS accepts no responsibility for any modification, redistribution or use of the CPM or any part thereof. The CPM is expressly intended for use by QAS paramedics whenperforming duties and de ...
... Service (‘QAS’) Clinical practice manual (‘CPM’) without the priorwritten permission of the Commissioner. The QAS accepts no responsibility for any modification, redistribution or use of the CPM or any part thereof. The CPM is expressly intended for use by QAS paramedics whenperforming duties and de ...
effects of cytochrome p450 enzyme inhibitors and inducers
... treat coexisting diseases making multiple drug therapy common in current clinical practice (Bucsa et al. 2012). However, some combinations may alter the exposure to drug or drugs with consequential undertreatment causing adverse effects. Pharmacokinetic drug-drug or drug-herb interactions can occur ...
... treat coexisting diseases making multiple drug therapy common in current clinical practice (Bucsa et al. 2012). However, some combinations may alter the exposure to drug or drugs with consequential undertreatment causing adverse effects. Pharmacokinetic drug-drug or drug-herb interactions can occur ...
Generics and public health - WHO archives
... Pharmaceutical equivalents: Products that contain the same amount of the same active substance(s) in the same dosage form; meet the same or comparable standards; are intended to be administered by the same route. Pharmaceutical equivalence does not necessarily imply therapeutic equivalence as differ ...
... Pharmaceutical equivalents: Products that contain the same amount of the same active substance(s) in the same dosage form; meet the same or comparable standards; are intended to be administered by the same route. Pharmaceutical equivalence does not necessarily imply therapeutic equivalence as differ ...
Drug Interactions Among HIV Patients Receiving
... HAART. DSPN occurs more frequently with stavudine (8%-52%) than with didanosine (17%-26%).5,6 Certain PIs and NRTIs (eg, saquinavir, ritonavir, and lamivudine) also have been implicated in the development of PN; however, the incidence tends to be lower compared with that seen with didanosine and sta ...
... HAART. DSPN occurs more frequently with stavudine (8%-52%) than with didanosine (17%-26%).5,6 Certain PIs and NRTIs (eg, saquinavir, ritonavir, and lamivudine) also have been implicated in the development of PN; however, the incidence tends to be lower compared with that seen with didanosine and sta ...
medicines control council biostudies
... characteristics of the dosage form containing the active pharmaceutical ingredient (API), should be well defined. Comparison of the therapeutic performances of two pharmaceutical products containing the same API, or active moiety is a critical means of assessing the possibility of using either the i ...
... characteristics of the dosage form containing the active pharmaceutical ingredient (API), should be well defined. Comparison of the therapeutic performances of two pharmaceutical products containing the same API, or active moiety is a critical means of assessing the possibility of using either the i ...
Anticaog_update_R_Maclean
... Summary: Anticoagulation for VTE • Patient choice • Rivaroxaban after a first VTE event (unless contraindicated), if unstable, side effects or contraindications to warfarin • LMWH if cancer, pregnant, interacting drugs with rivaroxaban – Once chemotherapy finished, consider switching from LMWH to a ...
... Summary: Anticoagulation for VTE • Patient choice • Rivaroxaban after a first VTE event (unless contraindicated), if unstable, side effects or contraindications to warfarin • LMWH if cancer, pregnant, interacting drugs with rivaroxaban – Once chemotherapy finished, consider switching from LMWH to a ...
May 2010 – November 2010 Literature Search - Hi
... Design Cross-sectional data was collected across 30 randomly selected Australian communities stratified to represent a range of socio-economic and regional variation. Setting Data were collected during school time from adolescents attending a broad range of schools. Participants The sample consisted ...
... Design Cross-sectional data was collected across 30 randomly selected Australian communities stratified to represent a range of socio-economic and regional variation. Setting Data were collected during school time from adolescents attending a broad range of schools. Participants The sample consisted ...
2009 PDL Standard Group and Carolina Direct
... CuraScript can also arrange convenient delivery directly to your home or your physician’s office and provide you with drug education, refill reminders, and even the necessary supplies, if applicable. Ask your physician to contact CuraScript at (888) 773-7376 to order these medications for you, or ca ...
... CuraScript can also arrange convenient delivery directly to your home or your physician’s office and provide you with drug education, refill reminders, and even the necessary supplies, if applicable. Ask your physician to contact CuraScript at (888) 773-7376 to order these medications for you, or ca ...
Drugs in Pregnancy: the Effects on Mother and Her
... continue to expose not only themselves but also their fetuses to the danger. Drugs during pregnancy can lead to insufficient nutrition of both mother and fetus. In addition, the risk of infection and sexually transmitted diseases increases in the case of non-sterile needle use. More frequent occurre ...
... continue to expose not only themselves but also their fetuses to the danger. Drugs during pregnancy can lead to insufficient nutrition of both mother and fetus. In addition, the risk of infection and sexually transmitted diseases increases in the case of non-sterile needle use. More frequent occurre ...
Amendments to the PM(NOC) Regulations
... Patented Medicines (Notice of Compliance) Regulations Eligibility for Protection under the Old Regulations Timing: the Canadian filing date of the patent must precede the date of the drug submission (priority filing does not count) The patent must contain a claim for the medicine itself or its ...
... Patented Medicines (Notice of Compliance) Regulations Eligibility for Protection under the Old Regulations Timing: the Canadian filing date of the patent must precede the date of the drug submission (priority filing does not count) The patent must contain a claim for the medicine itself or its ...
The Nebraska Medical Center Guidelines for Management of
... • Itraconazole is generally reserved for mucosal candidiasis, and little data exist for IC. GI absorption differs for capsule versus solution. Acid-reducing agents decrease absorption of the capsule, while food and acidic beverages (such as carbonated drinks and cranberry juice) enhance absorption. ...
... • Itraconazole is generally reserved for mucosal candidiasis, and little data exist for IC. GI absorption differs for capsule versus solution. Acid-reducing agents decrease absorption of the capsule, while food and acidic beverages (such as carbonated drinks and cranberry juice) enhance absorption. ...
Drugs acting on the uterus
... Clinical uses to oxytocin: - Induction of labor Drug of choice given in units in an I.V infusion - Postpartum hemorrhage, I.M. Ergot alkaloids are better (ergonovine, methylergonovine, syntometrine= oxytocin+ ergometrine) - Breast engorgement, intranasally - Abortifacient, I.V infusion. ≥ 20 weeks ...
... Clinical uses to oxytocin: - Induction of labor Drug of choice given in units in an I.V infusion - Postpartum hemorrhage, I.M. Ergot alkaloids are better (ergonovine, methylergonovine, syntometrine= oxytocin+ ergometrine) - Breast engorgement, intranasally - Abortifacient, I.V infusion. ≥ 20 weeks ...
P4 - ADVANCED PHARMACY PRACTICE EXPERIENCE (APPE) PRECEPTOR MANUAL
... The goals and objectives for each experience are based on the ability statements needed to fulfill the requirements for the Doctor of Pharmacy degree. Students must demonstrate a minimum level of proficiency for each ability by the end of the experiential education program in order to receive credit ...
... The goals and objectives for each experience are based on the ability statements needed to fulfill the requirements for the Doctor of Pharmacy degree. Students must demonstrate a minimum level of proficiency for each ability by the end of the experiential education program in order to receive credit ...
Will They Turn You into a Zombie? - Center for Applied Behavioral
... • Brand names include: “Spice,” “K2,” fake weed, “Yucatan Fire,” “Skunk,” “Moon Rocks,” herbal incense, “Crazy Clown,” “Herbal Madness” • Labeled “not for human consumption” • Contain dried, shredded plant material (inert) and chemical additives ...
... • Brand names include: “Spice,” “K2,” fake weed, “Yucatan Fire,” “Skunk,” “Moon Rocks,” herbal incense, “Crazy Clown,” “Herbal Madness” • Labeled “not for human consumption” • Contain dried, shredded plant material (inert) and chemical additives ...
IFU - Beckman Coulter
... of Abuse Testing (DAT) Urine Calibrators, is intended for the qualitative determination of methaqualone in human urine at a cutoff value of 300 ng/mL. The METQ assay provides a rapid screening procedure for determining the presence of methaqualone (METQ) and its metabolites in urine. This test provi ...
... of Abuse Testing (DAT) Urine Calibrators, is intended for the qualitative determination of methaqualone in human urine at a cutoff value of 300 ng/mL. The METQ assay provides a rapid screening procedure for determining the presence of methaqualone (METQ) and its metabolites in urine. This test provi ...
Immediate hypersensitivity to penicillins with negative skin tests
... limit therapeutic options and consequently alter the pattern of microbial resistances and increase socio-economic costs (2). For these reasons, the study of all suspected cases of penicillins hypersensitivity is highly important, to avoid the unnecessary use of less efficient or more expensive alter ...
... limit therapeutic options and consequently alter the pattern of microbial resistances and increase socio-economic costs (2). For these reasons, the study of all suspected cases of penicillins hypersensitivity is highly important, to avoid the unnecessary use of less efficient or more expensive alter ...
AN IMPROVEMENT IN PHYSICOCHEMICAL PROPERTIES OF
... India) using the paddle method (USP Type II). Dissolution studies were carried out using 900 mL of 0.1 M HCl (pH 1.2) at 37 ± 0.5OC at 50 rpm according to US FDA guidelines (16, 17). Carvedilol (12.5 mg) or its equivalent amount of spherical agglomerates were added to 900 mL of 0.1 M HCl (pH 1.2). S ...
... India) using the paddle method (USP Type II). Dissolution studies were carried out using 900 mL of 0.1 M HCl (pH 1.2) at 37 ± 0.5OC at 50 rpm according to US FDA guidelines (16, 17). Carvedilol (12.5 mg) or its equivalent amount of spherical agglomerates were added to 900 mL of 0.1 M HCl (pH 1.2). S ...
Pharmacokinetics
Pharmacokinetics, sometimes abbreviated as PK (from Ancient Greek pharmakon ""drug"" and kinetikos ""moving, putting in motion""; see chemical kinetics), is a branch of pharmacology dedicated to determining the fate of substances administered externally to a living organism. The substances of interest include pharmaceutical agents, hormones, nutrients, and toxins. It attempts to discover the fate of a drug from the moment that it is administered up to the point at which it is completely eliminated from the body.Pharmacokinetics describes how the body affects a specific drug after administration through the mechanisms of absorption and distribution, as well as the chemical changes of the substance in the body (e.g. by metabolic enzymes such as cytochrome P450 or glucuronosyltransferase enzymes), and the effects and routes of excretion of the metabolites of the drug. Pharmacokinetic properties of drugs may be affected by elements such as the site of administration and the dose of administered drug. These may affect the absorption rate. Pharmacokinetics is often studied in conjunction with pharmacodynamics, the study of a drug's pharmacological effect on the body.A number of different models have been developed in order to simplify conceptualization of the many processes that take place in the interaction between an organism and a drug. One of these models, the multi-compartment model, gives the best approximation to reality; however, the complexity involved in using this type of model means that monocompartmental models and above all two compartmental models are the most-frequently used. The various compartments that the model is divided into are commonly referred to as the ADME scheme (also referred to as LADME if liberation is included as a separate step from absorption): Liberation - the process of release of a drug from the pharmaceutical formulation. See also IVIVC. Absorption - the process of a substance entering the blood circulation. Distribution - the dispersion or dissemination of substances throughout the fluids and tissues of the body. Metabolization (or biotransformation, or inactivation) – the recognition by the organism that a foreign substance is present and the irreversible transformation of parent compounds into daughter metabolites. Excretion - the removal of the substances from the body. In rare cases, some drugs irreversibly accumulate in body tissue.The two phases of metabolism and excretion can also be grouped together under the title elimination.The study of these distinct phases involves the use and manipulation of basic concepts in order to understand the process dynamics. For this reason in order to fully comprehend the kinetics of a drug it is necessary to have detailed knowledge of a number of factors such as: the properties of the substances that act as excipients, the characteristics of the appropriate biological membranes and the way that substances can cross them, or the characteristics of the enzyme reactions that inactivate the drug.All these concepts can be represented through mathematical formulas that have a corresponding graphical representation. The use of these models allows an understanding of the characteristics of a molecule, as well as how a particular drug will behave given information regarding some of its basic characteristics. Such as its acid dissociation constant (pKa), bioavailability and solubility, absorption capacity and distribution in the organism.The model outputs for a drug can be used in industry (for example, in calculating bioequivalence when designing generic drugs) or in the clinical application of pharmacokinetic concepts. Clinical pharmacokinetics provides many performance guidelines for effective and efficient use of drugs for human-health professionals and in veterinary medicine.