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2014 ACC/AHA Guideline on Perioperative Cardiovascular
2014 ACC/AHA Guideline on Perioperative Cardiovascular

... Methodology Summit Report (3) and 2014 perspective article (4). This perspective (4) recounts the history of ...
Mortality Study of the Significance of Extrasystoles in an
Mortality Study of the Significance of Extrasystoles in an

... with this finding who were followed for an average period of 18 years. At the end of the study 356 persons were alive and 125 were dead. Two hundred and thirty-one persons had terminated their policies at a prior date by maturity or discontinuance and were not followed further. Although the lack of ...
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery

... and supporting text, the writing committee uses evidencebased methodologies developed by the Task Force (1). The Class of Recommendation (COR) is an estimate of the size of the treatment effect considering risks versus benefits in addition to evidence and/or agreement that a given treatment or proce ...
Role of Coronary Vasoconstriction in Ischemic Heart - J
Role of Coronary Vasoconstriction in Ischemic Heart - J

... Atherothrombosis has long been recognized as an important mechanism of cardiac events in ischemic heart disease, and large multicenter clinical studies have shown the benefit of antiplatelet agents, statins,β-blockers and angiotensin converting enzyme inhibitors in preventing these events. However, ...
Cardiovascular Responses to Exercise in Middle-aged
Cardiovascular Responses to Exercise in Middle-aged

... after bedrest. The decrease in peak oxygen uptake after bedrest was greater during upright exercise (lS.lo%,p < 0.05) than during supine exercise (6.1%, NS): from 25.8 ± 5.2 to 21.9 ± 4.5 ml/kg/min and from 24.6 ± 5.2 to 23.1 ± 4.8 ml/kg/min. The decrease in submaximal work was also greater in the u ...
Heart rate as a marker of incidence and prognosis of cardiovascular
Heart rate as a marker of incidence and prognosis of cardiovascular

... higher risk of cardiovascular outcomes not currently considered as primary endpoints in trials, such as heart failure. Finally, higher HR is strongly associated with atrial fibrillation in men, but not in women. ...
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery:
2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery:

... and supporting text, the writing committee uses evidencebased methodologies developed by the Task Force (1). The Class of Recommendation (COR) is an estimate of the size of the treatment effect considering risks versus benefits in addition to evidence and/or agreement that a given treatment or proce ...
ACC/AHA/ACP-ASIM Guidelines for the Management
ACC/AHA/ACP-ASIM Guidelines for the Management

... a major public health problem. Chronic stable angina is the initial manifestation of ischemic heart disease in approximately one half of patients (3,4). It is difficult to estimate the number of patients with chronic chest pain syndromes in the U.S. who fall within these guidelines, but clearly it i ...
Anomalous origin of the right coronary artery
Anomalous origin of the right coronary artery

... the LAD is usually benign, and does not interfere with coronary perfusion. However, if an abnormal coronary artery crosses between the PA and the aorta, myocardial ischemia and sudden death may occur [1–12, 23, 30, 37]. The clinical relevance of this coronary anomaly may be due to underlying coronar ...
Original Article
Original Article

... reduced LVEF when compared with baseline. Mice that consumed 0.12% TMAO exhibited significantly worse cardiac function in all parameters measured after TAC (Figure 2) when compared with mice fed the control diet. An accelerated progression of cardiac dilatation, as evidenced by significantly increas ...
Variations of origin of coronary artery and their importance
Variations of origin of coronary artery and their importance

... of view it would be beneficial that both coronary ostia were above the intercommissural line. This would make the coronary blood flow easier during ventricular systole and would also prevent the obstruction of the ostia when the aortic valve was opened. However Cavalcanti, Melo and Vasconcelos (2003 ...
If Inhibition, Heart Rate, and Coronary Artery Disease
If Inhibition, Heart Rate, and Coronary Artery Disease

... substrate is almost invariably atheromatous narrowing of the coronary artery, although other factors may be involved. The anginal episode lasts typically several minutes and is commonly triggered by an increase in heart rate and blood pressure occurring during exertion, eating, and/or stress and whi ...
Evaluation of Syncope
Evaluation of Syncope

... phases: a prodrome, loss of consciousness, and a postsyncopal phase. A precipitating event or situation (e.g., emotional stress, trauma, pain, sight of blood, prolonged standing) usually is identifiable. The prodrome, characterized by diaphoresis, epigastric discomfort, extreme fatigue, weakness, ya ...
Increasing survival rate from commotio cordis
Increasing survival rate from commotio cordis

... perhaps not an entirely unexpected finding, given the known effectiveness of public access defibrillation in restoring normal rhythm following out-of-hospital cardiac arrest,15–18 as well as the increasing availability of AEDs over the last several years. Indeed, defibrillation and prompt response t ...
Pediatric Pulmonary Hypertension
Pediatric Pulmonary Hypertension

... management of pediatric PH remains challenging because treatment decisions continue to depend largely on results from evidence-based adult studies and the clinical experience of pediatric experts. (J Am Coll Cardiol 2013;62:D117–26) ª 2013 by the American College of Cardiology Foundation ...
Human coronary sinus — from Galen to modern times
Human coronary sinus — from Galen to modern times

... details still remain obscure, although most of modern procedures require deep anatomical knowledge on cardiac veins. Many of developmental remarks are still not clear, regarded to development of the vessels of the heart in association with origin of heart conductive system. Key words: coronary sinus ...
Curriculum Vitae: Rachel Lampert
Curriculum Vitae: Rachel Lampert

... Common genes contribute to depressive symptoms and heart rate variability: The Twins Heart Study. Twin Research & Human Genetics. 13(1):1-9, 2010 Feb. ...
Haemodynamics in Essential Hypertension
Haemodynamics in Essential Hypertension

... patients with more severe, but labile, hypertension) demonstrated normal heart rate and increased stroke volume (Finkielman, Worcel & Agrest, 1965). The calculated total peripheral resistance is not significantly higher than in controls. Individual variations are great, however, and a continuous spe ...
Coronary Venous Anatomy and its Relevance Suma HY‡, Hariharan
Coronary Venous Anatomy and its Relevance Suma HY‡, Hariharan

... Morique et al., 2005). In the present study, Suma, Coronary venous anatomy ...
Thrombus aspiration for treating distal coronary macroemboli during
Thrombus aspiration for treating distal coronary macroemboli during

... coronary syndromes [1, 2]. The recently published Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS), the largest randomised study of a thrombectomy device published to date, which includes 1,071 STEMI patients, has stimulated interest in this ...
PDF file - Kardiologia Polska
PDF file - Kardiologia Polska

... glycoprotein IIb/IIIa inhibitors were administered as clinically indicated during the procedure. The radial sheath was immediately removed at the end of the procedure and a radial compression device (TR Band, Terumo, Tokyo, Japan) was applied at the access site. ...
Glucocorticoid receptor alters isovolumetric contraction and restrains
Glucocorticoid receptor alters isovolumetric contraction and restrains

... exert a variety of effects on the cardiovascular system. Excessive glucocorticoid levels, whether endogenous as in Cushing’s disease, or exogenous through pharmacotherapy, are associated with increased risk of cardiovascular disease and heart failure (Souverein et al. 2004, Walker 2007). In contrast ...
- The Journal of Thoracic and Cardiovascular Surgery
- The Journal of Thoracic and Cardiovascular Surgery

... of preexisting myocytes (hypertrophy). In the embryonic and fetal stages, cardiac growth is primarily because of hyperplasia, and this process persists during the neonatal life. The mitotic activity and the potential for hyperplasia of myocytes are probably lost between 3 and 6 months of age, and th ...
Cardiac Arrhythmias (Part 2)
Cardiac Arrhythmias (Part 2)

... altered cardiac index from 3.67 to 3.72 liters/ min/m2. Further increases in atrial pacing rate caused a small decrease in flow to 3.2 liters/min/m2. Stein et al.9 reported similar results. On the other hand Samet et al.10 reported data on the effect of right atrial pacing in 33 normal subjects and ...
Eligibility and Disqualification Recommendations for Competitive
Eligibility and Disqualification Recommendations for Competitive

... implantable devices (e.g., pacemakers and cardioverterdefibrillators) has created greater numbers of physically ...
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Cardiovascular disease



Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.
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