Angiotensin-converting enzyme in cardiovascular function and dysfunction Liza Ljungberg
... been linked to increased risk for cardiovascular disease. This thesis aimed to explore the connection between ACE and cardiovascular function and dysfunction. The impact of nicotine and nicotine metabolites on ACE in cultured human endothelial cells was studied. Nicotine as well as nicotine metaboli ...
... been linked to increased risk for cardiovascular disease. This thesis aimed to explore the connection between ACE and cardiovascular function and dysfunction. The impact of nicotine and nicotine metabolites on ACE in cultured human endothelial cells was studied. Nicotine as well as nicotine metaboli ...
The circadian clock within the heart: potential influence - AJP
... undergo phosphorylation in a circadian-like fashion; in addition to its influence on protein stability, increasing evidence ...
... undergo phosphorylation in a circadian-like fashion; in addition to its influence on protein stability, increasing evidence ...
PRACTICE GUIDELINE 2011 ACCF/AHA/SCAI Guideline for
... evidence for or against particular tests, treatments, or procedures; and include estimates of expected outcomes where such data exist. Patient-specific modifiers, comorbidities, and issues of patient preference that may influence the choice of tests or therapies are considered. When available, infor ...
... evidence for or against particular tests, treatments, or procedures; and include estimates of expected outcomes where such data exist. Patient-specific modifiers, comorbidities, and issues of patient preference that may influence the choice of tests or therapies are considered. When available, infor ...
ACCF/ACR/AIUM/ASE/ASN/ICAVL/SCAI/SCCT/SIR/SVM/SVS 2012
... delivery, and reimbursement policy. Furthermore, recognition of uncertain clinical scenarios facilitates identification of areas that would benefit from future research. ...
... delivery, and reimbursement policy. Furthermore, recognition of uncertain clinical scenarios facilitates identification of areas that would benefit from future research. ...
Quality Improvement Guidelines for Angiography, Angioplasty
... and multiplicity; the resistance of the distal vascular bed; and the available collateral blood supply (26). Although mild stenoses are of no hemodynamic significance, most angiographers would agree that a stenosis that narrows the luminal diameter by 75% almost certainly is significant (27,28). The ...
... and multiplicity; the resistance of the distal vascular bed; and the available collateral blood supply (26). Although mild stenoses are of no hemodynamic significance, most angiographers would agree that a stenosis that narrows the luminal diameter by 75% almost certainly is significant (27,28). The ...
Myocardial infarction with Q waves
... The emergence of ischemia of the heart muscle leads to profound disturbances in the metabolism of myocardial cells and the vascular system of the heart. As a result of the termination or significant limitation of coronary blood flow develop hypoxia, which disturbs the synthesis of ATP in mitochondri ...
... The emergence of ischemia of the heart muscle leads to profound disturbances in the metabolism of myocardial cells and the vascular system of the heart. As a result of the termination or significant limitation of coronary blood flow develop hypoxia, which disturbs the synthesis of ATP in mitochondri ...
Severe paediatric pulmonary hypertension: new management strategies REVIEW A Rashid, D Ivy
... Despite appropriate surgical correction, pulmonary hypertension and pulmonary vascular disease may progress. As vasoconstriction is an important component in the development of medial hypertrophy, vasodilators are frequently used to decrease pulmonary artery pressure, improve cardiac output, and pot ...
... Despite appropriate surgical correction, pulmonary hypertension and pulmonary vascular disease may progress. As vasoconstriction is an important component in the development of medial hypertrophy, vasodilators are frequently used to decrease pulmonary artery pressure, improve cardiac output, and pot ...
Moderate Systemic Hypotension During
... The LAD artery was then occluded for 1 h when the snare was released, and reperfusion was established for 2 h. The animals were excluded from the study if the baseline mean ABP was ⬍ 75 mm Hg. Two groups were studied. In group 1 (n ⫽ 13), IV nitroglycerin was infused during the reperfusion period at ...
... The LAD artery was then occluded for 1 h when the snare was released, and reperfusion was established for 2 h. The animals were excluded from the study if the baseline mean ABP was ⬍ 75 mm Hg. Two groups were studied. In group 1 (n ⫽ 13), IV nitroglycerin was infused during the reperfusion period at ...
Coronary computed tomography angiography: a new wave of
... heart rhythm, coronary CTA in patients with markedly irregular heart rhythm, such as atrial fibrillation or frequent premature complexes, may not produce a good image quality. It is more certainly so if coronary CTA is performed using MDCT scanners that require a few rotations to ‘stitch’ up cardiac ...
... heart rhythm, coronary CTA in patients with markedly irregular heart rhythm, such as atrial fibrillation or frequent premature complexes, may not produce a good image quality. It is more certainly so if coronary CTA is performed using MDCT scanners that require a few rotations to ‘stitch’ up cardiac ...
Patient-Specific Modeling of Blood Flow and Pressure in Human
... range. However, the right coronary flow does not decrease in systole because the right ventricle operates in a lower pressure range than the left ventricle.17 Even the maximum right ventricular pressure is one-fifth of the average aortic pressure.17 To accommodate the change in the intramyorcardial pr ...
... range. However, the right coronary flow does not decrease in systole because the right ventricle operates in a lower pressure range than the left ventricle.17 Even the maximum right ventricular pressure is one-fifth of the average aortic pressure.17 To accommodate the change in the intramyorcardial pr ...
The Posterior Ventricular Branches of the Coronary Arteries in the
... The clinical application of the anatomical study of the ventricular branches of coronary arteries is the execution and interpretation of examination methods and the planning and performing of cardiovascular disease treatment 1-6. In 1940, Schlesinger 1 developed the anatomical concept of balance or ...
... The clinical application of the anatomical study of the ventricular branches of coronary arteries is the execution and interpretation of examination methods and the planning and performing of cardiovascular disease treatment 1-6. In 1940, Schlesinger 1 developed the anatomical concept of balance or ...
COCATS 2
... medicine. It should provide a broad exposure to acute and chronic cardiovascular diseases, emphasizing accurate ambulatory and bedside clinical diagnosis, appropriate use of diagnostic studies, and integration of all data into a wellcommunicated consultation, with sensitivity to the unique features ...
... medicine. It should provide a broad exposure to acute and chronic cardiovascular diseases, emphasizing accurate ambulatory and bedside clinical diagnosis, appropriate use of diagnostic studies, and integration of all data into a wellcommunicated consultation, with sensitivity to the unique features ...
Acute and Chronic Effects of Epicardial Radiofrequency Applications
... is available regarding the chronic effects of delivering radiofrequency in the vicinity of large coronary vessels, and the long-term impact of this approach for mapping and ablation on epicardial vessel integrity is poorly understood. Therefore, the aim of this study was to characterize the acute an ...
... is available regarding the chronic effects of delivering radiofrequency in the vicinity of large coronary vessels, and the long-term impact of this approach for mapping and ablation on epicardial vessel integrity is poorly understood. Therefore, the aim of this study was to characterize the acute an ...
Comprehensive characterisation of hypertensive heart disease left
... native T1 values (1054±41 ms) compared with those with LV remodelling (1029±45 ms), normal LV (1031±35 ms) and controls (1024±41 ms) (table 3). These findings for native T1 and ECV persisted after correction for covariates (table 4). The increased indexed LVM in concentric LVH compared with subjects ...
... native T1 values (1054±41 ms) compared with those with LV remodelling (1029±45 ms), normal LV (1031±35 ms) and controls (1024±41 ms) (table 3). These findings for native T1 and ECV persisted after correction for covariates (table 4). The increased indexed LVM in concentric LVH compared with subjects ...
Saccular Aneurysm of the Proximal Left Common Carotid Artery
... intraluminal thrombosis had occurred (fig . 1 B). No thrombus visibly protruded into the parent vessel. Five days later, surgery was done to interpose a Dacron graft between the supraclavicular segment of the left common carotid artery and the left subclavian artery, and the stump of the proximal le ...
... intraluminal thrombosis had occurred (fig . 1 B). No thrombus visibly protruded into the parent vessel. Five days later, surgery was done to interpose a Dacron graft between the supraclavicular segment of the left common carotid artery and the left subclavian artery, and the stump of the proximal le ...
Coronary CT angiography: current status and continuing challenges
... ABSTRACT. Coronary CT angiography has been increasingly used in the diagnosis of coronary artery disease owing to rapid technological developments, which are reflected in the improved spatial and temporal resolution of the images. High diagnostic accuracy has been achieved with multislice CT scanner ...
... ABSTRACT. Coronary CT angiography has been increasingly used in the diagnosis of coronary artery disease owing to rapid technological developments, which are reflected in the improved spatial and temporal resolution of the images. High diagnostic accuracy has been achieved with multislice CT scanner ...
ACCF/SCAI/STS/AATS/AHA/ASNC/HFSA/SCCT 2012 Appropriate
... In addition, since the publication of the original document, efforts to implement data collection protocols related to the AUC indications identified a gap in the clinical scenarios related to lower-risk unstable angina/non–STsegment elevation myocardial infarction (UA/NSTEMI) patients and asymptoma ...
... In addition, since the publication of the original document, efforts to implement data collection protocols related to the AUC indications identified a gap in the clinical scenarios related to lower-risk unstable angina/non–STsegment elevation myocardial infarction (UA/NSTEMI) patients and asymptoma ...
Third universal definition of myocardial infarction
... burden of CAD within and across populations, especially if standardized data are collected in a manner that dis tinguishes between incident and recurrent events. From the epidemiological point of view, the incidence of MI in a population can be used as a proxy for the prevalence of CAD in that popu ...
... burden of CAD within and across populations, especially if standardized data are collected in a manner that dis tinguishes between incident and recurrent events. From the epidemiological point of view, the incidence of MI in a population can be used as a proxy for the prevalence of CAD in that popu ...
File
... The American College of Cardiology (ACC) and the American Heart Association (AHA) are committed to the prevention and management of cardiovascular diseases through professional education and research for clinicians, providers, and patients. Since 1980, the ACC and AHA have shared a responsibility to ...
... The American College of Cardiology (ACC) and the American Heart Association (AHA) are committed to the prevention and management of cardiovascular diseases through professional education and research for clinicians, providers, and patients. Since 1980, the ACC and AHA have shared a responsibility to ...
Surgical Treatment of Coronary Artery Disease
... three-vessel or left main artery disease, severe angina, or a positive pretreatment exercise stress test. • Most trials comparing CABG with catheter-based interventions (CBIs) in patients with multivessel disease have shown similar short-term survival benefits for both treatments, but CBIs have been ...
... three-vessel or left main artery disease, severe angina, or a positive pretreatment exercise stress test. • Most trials comparing CABG with catheter-based interventions (CBIs) in patients with multivessel disease have shown similar short-term survival benefits for both treatments, but CBIs have been ...
Improving Chronic Disease Management - Health
... “Today in the United States chronic disease is the major cause of disability, is the main reason why people seek health care, and consumes 70% of health care spending. With acute disease, the treatment aims at return to normal. With chronic disease, the patient’s life is irreversibly changed. Neithe ...
... “Today in the United States chronic disease is the major cause of disability, is the main reason why people seek health care, and consumes 70% of health care spending. With acute disease, the treatment aims at return to normal. With chronic disease, the patient’s life is irreversibly changed. Neithe ...
a guideline for healthcare professionals from the American
... troke remains a major healthcare problem. Its human and economic toll is staggering. Approximately 795 000 people in the United States have a stroke each year, of which about 610 000 are a first attack; and 6.4 million Americans are stroke survivors.1 Stroke is also estimated to result in 134 000 de ...
... troke remains a major healthcare problem. Its human and economic toll is staggering. Approximately 795 000 people in the United States have a stroke each year, of which about 610 000 are a first attack; and 6.4 million Americans are stroke survivors.1 Stroke is also estimated to result in 134 000 de ...
PATTERNS OF HUMAN MYOCARDIAL OXYGEN EXTRACTION
... coronary blood flow and oxygen extraction from the arterial blood. The myocardial oxygen extraction coefficient (1) expresses the fraction of available oxygen in arterial blood removed by the myocardium: coronary A-Vo2/Ao2 X 100 = myocardial extraction percentage. Myocardial oxygen extraction during ...
... coronary blood flow and oxygen extraction from the arterial blood. The myocardial oxygen extraction coefficient (1) expresses the fraction of available oxygen in arterial blood removed by the myocardium: coronary A-Vo2/Ao2 X 100 = myocardial extraction percentage. Myocardial oxygen extraction during ...
2014 ACC/AHA Guideline on Perioperative Cardiovascular
... Methodology Summit Report (3) and 2014 perspective article (4). This perspective (4) recounts the history of ...
... Methodology Summit Report (3) and 2014 perspective article (4). This perspective (4) recounts the history of ...
Cardiovascular disease
Cardiovascular disease (CVD) is a class of diseases that involve the heart or blood vessels. Cardiovascular disease includes coronary artery diseases (CAD) such as angina and myocardial infarction (commonly known as a heart attack). Other CVDs are stroke, hypertensive heart disease, rheumatic heart disease, cardiomyopathy, atrial fibrillation, congenital heart disease, endocarditis, aortic aneurysms, peripheral artery disease and venous thrombosis.The underlying mechanisms vary depending on the disease in question. Coronary artery disease, stroke, and peripheral artery disease involve atherosclerosis. This may be caused by high blood pressure, smoking, diabetes, lack of exercise, obesity, high blood cholesterol, poor diet, and excessive alcohol consumption, among others. High blood pressure results in 13% of CVD deaths, while tobacco results in 9%, diabetes 6%, lack of exercise 6% and obesity 5%. Rheumatic heart disease may follow untreated strep throat.It is estimated that 90% of CVD is preventable. Prevention of atherosclerosis is by decreasing risk factors through: healthy eating, exercise, avoidance of tobacco smoke and limiting alcohol intake. Treating high blood pressure and diabetes is also beneficial. Treating people who have strep throat with antibiotics can decrease the risk of rheumatic heart disease. The effect of the use of aspirin in people who are otherwise healthy is of unclear benefit. The United States Preventive Services Task Force recommends against its use for prevention in women less than 55 and men less than 45 years old; however, in those who are older it is recommends in some individuals. Treatment of those who have CVD improves outcomes.Cardiovascular diseases are the leading cause of death globally. This is true in all areas of the world except Africa. Together they resulted in 17.3 million deaths (31.5%) in 2013 up from 12.3 million (25.8%) in 1990. Deaths, at a given age, from CVD are more common and have been increasing in much of the developing world, while rates have declined in most of the developed world since the 1970s. Coronary artery disease and stroke account for 80% of CVD deaths in males and 75% of CVD deaths in females. Most cardiovascular disease affects older adults. In the United States 11% of people between 20 and 40 have CVD, while 37% between 40 and 60, 71% of people between 60 and 80, and 85% of people over 80 have CVD. The average age of death from coronary artery disease in the developed world is around 80 while it is around 68 in the developing world. Disease onset is typically seven to ten years earlier in men as compared to women.